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A transcription-driven microgel network poised near the sol-gel transition
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/ajmg.a.38388openalex-snapshot
Clinical and molecular characterization of de novo loss of function variants in HNRNPU
inferredcites →https://doi.org/10.1002/ajmg.a.38492openalex-snapshot
De novo mutations in HNRNPU result in a neurodevelopmental syndrome
inferredcites →https://doi.org/10.1002/anie.202204311openalex-snapshot
Phase Separation of Heterogeneous Nuclear Ribonucleoprotein A1 upon Specific RNA‐Binding Observed by Magnetic Resonance**
inferredcites →https://doi.org/10.1002/j.1460-2075.1992.tb05331.xopenalex-snapshot
Primary structure and binding activity of the hnRNP U protein: binding RNA through RGG box.
inferredcites →https://doi.org/10.1002/j.1460-2075.1992.tb05422.xopenalex-snapshot
Characterization of SAF‐A, a novel nuclear DNA binding protein from HeLa cells with high affinity for nuclear matrix/scaffold attachment DNA elements.
inferredcites →https://doi.org/10.1002/pro.4582openalex-snapshot
Using evolutionary data to make sense of macromolecules with a “face‐lifted” ConSurf
inferredcites →https://doi.org/10.1006/jcph.1995.1039openalex-snapshot
Fast Parallel Algorithms for Short-Range Molecular Dynamics
inferredcites →https://doi.org/10.1007/978-1-0716-1036-7_13openalex-snapshot
Alignment of Biological Sequences with Jalview
inferredcites →https://doi.org/10.1007/978-1-4939-9546-2_15openalex-snapshot
BioID as a Tool for Protein-Proximity Labeling in Living Cells
inferredcites →https://doi.org/10.1007/s00412-003-0258-0openalex-snapshot
Scaffold attachment factor A (SAF-A) is concentrated in inactive X�chromosome territories through its RGG domain
inferredcites →https://doi.org/10.1007/s00439-016-1683-5openalex-snapshot
The hnRNP family: insights into their role in health and disease
inferredcites →https://doi.org/10.1007/s00439-017-1795-6openalex-snapshot
Heterozygous HNRNPU variants cause early onset epilepsy and severe intellectual disability
inferredcites →https://doi.org/10.1007/s11248-004-8147-8openalex-snapshot
Hypomorphic mutation in hnRNP U results in post-implantation lethality
inferredcites →https://doi.org/10.1016/0092-8674(93)90235-iopenalex-snapshot
Visualization of replication factories attached to a nucleoskeleton
inferredcites →https://doi.org/10.1016/b978-0-12-420120-0.00008-6openalex-snapshot
PAR-CLIP (Photoactivatable Ribonucleoside-Enhanced Crosslinking and Immunoprecipitation)
inferredcites →https://doi.org/10.1016/j.ajpath.2017.09.017openalex-snapshot
Haploinsufficiency of hnRNP U Changes Activity Pattern and Metabolic Rhythms
inferredcites →https://doi.org/10.1016/j.bpj.2017.01.025openalex-snapshot
Ephemeral Protein Binding to DNA Shapes Stable Nuclear Bodies and Chromatin Domains
inferredcites →https://doi.org/10.1016/j.ceb.2019.03.007openalex-snapshot
Role of nuclear RNA in regulating chromatin structure and transcription
inferredcites →https://doi.org/10.1016/j.cell.2004.08.011openalex-snapshot
Chromatin Architecture of the Human Genome
inferredcites →https://doi.org/10.1016/j.cell.2014.01.042openalex-snapshot
Stable C0T-1 Repeat RNA Is Abundant and Is Associated with Euchromatic Interphase Chromosomes
inferredcites →https://doi.org/10.1016/j.cell.2015.09.015openalex-snapshot
Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
inferredcites →https://doi.org/10.1016/j.cell.2017.05.029openalex-snapshot
SAF-A Regulates Interphase Chromosome Structure through Oligomerization with Chromatin-Associated RNAs
inferredcites →https://doi.org/10.1016/j.cell.2019.08.037openalex-snapshot
Organization of Chromatin by Intrinsic and Regulated Phase Separation
inferredcites →https://doi.org/10.1016/j.cell.2020.11.027openalex-snapshot
Condensed Chromatin Behaves like a Solid on the Mesoscale In Vitro and in Living Cells
inferredcites →https://doi.org/10.1016/j.cell.2020.11.044openalex-snapshot
Chromatin: Liquid or Solid?
inferredcites →https://doi.org/10.1016/j.celrep.2012.02.001openalex-snapshot
Integrative Genome-wide Analysis Reveals Cooperative Regulation of Alternative Splicing by hnRNP Proteins
inferredcites →https://doi.org/10.1016/j.celrep.2012.11.008openalex-snapshot
Local Nucleosome Dynamics Facilitate Chromatin Accessibility in Living Mammalian Cells
inferredcites →https://doi.org/10.1016/j.celrep.2020.108177openalex-snapshot
Common Fragile Sites Are Characterized by Faulty Condensin Loading after Replication Stress
inferredcites →https://doi.org/10.1016/j.cossms.2011.07.003openalex-snapshot
Reversible gels of patchy particles
inferredcites →https://doi.org/10.1016/j.devcel.2010.08.006openalex-snapshot
The Matrix Protein hnRNP U Is Required for Chromosomal Localization of Xist RNA
inferredcites →https://doi.org/10.1016/j.devcel.2022.11.014openalex-snapshot
RNA degradation eliminates developmental transcripts during murine embryonic stem cell differentiation via CAPRIN1-XRN2
inferredcites →https://doi.org/10.1016/j.gde.2021.10.008openalex-snapshot
The role of SAF-A/hnRNP U in regulating chromatin structure
inferredcites →https://doi.org/10.1016/j.gde.2022.101940openalex-snapshot
The ribonucleoprotein network of the nucleus: a historical perspective
inferredcites →https://doi.org/10.1016/j.isci.2022.105797openalex-snapshot
Evidence of shared transcriptomic dysregulation of HNRNPU-related disorder between human organoids and embryonic mice
inferredcites →https://doi.org/10.1016/j.jmb.2022.167529openalex-snapshot
Missense Variants Reveal Functional Insights Into the Human ARID Family of Gene Regulators
inferredcites →https://doi.org/10.1016/j.molcel.2010.10.013openalex-snapshot
Analysis of Active and Inactive X Chromosome Architecture Reveals the Independent Organization of 30 nm and Large-Scale Chromatin Structures
inferredcites →https://doi.org/10.1016/j.molcel.2012.01.009openalex-snapshot
Nuclear Matrix Factor hnRNP U/SAF-A Exerts a Global Control of Alternative Splicing by Regulating U2 snRNP Maturation
inferredcites →https://doi.org/10.1016/j.molcel.2013.05.021openalex-snapshot
Defining the RGG/RG Motif
inferredcites →https://doi.org/10.1016/j.molcel.2015.08.018openalex-snapshot
Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins
inferredcites →https://doi.org/10.1016/j.molcel.2015.09.026openalex-snapshot
Effects of Transcription Elongation Rate and Xrn2 Exonuclease Activity on RNA Polymerase II Termination Suggest Widespread Kinetic Competition
inferredcites →https://doi.org/10.1016/j.molcel.2017.06.018openalex-snapshot
Dynamic Organization of Chromatin Domains Revealed by Super-Resolution Live-Cell Imaging
inferredcites →https://doi.org/10.1016/j.molcel.2021.07.004openalex-snapshot
Nascent RNA scaffolds contribute to chromosome territory architecture and counter chromatin compaction
inferredcites →https://doi.org/10.1016/j.tcb.2018.12.003openalex-snapshot
RNA: Nuclear Glue for Folding the Genome
inferredcites →https://doi.org/10.1016/j.tig.2021.11.001openalex-snapshot
Predicting genome organisation and function with mechanistic modelling.
inferredcites →https://doi.org/10.1016/s0968-0004(97)01049-9openalex-snapshot
SPRY domains in ryanodine receptors (Ca2+-release channels)
inferredcites →https://doi.org/10.1021/acs.accounts.6b00544openalex-snapshot
Functional Microgels and Microgel Systems
inferredcites →https://doi.org/10.1021/acs.biochem.3c00510openalex-snapshot
The RNA-Binding Domain of hnRNP U Extends beyond the RGG/RG Motifs
inferredcites →https://doi.org/10.1021/acs.macromol.7b01600openalex-snapshot
In Silico Synthesis of Microgel Particles
inferredcites →https://doi.org/10.1021/bi00200a024openalex-snapshot
Purification of Two Isoforms of hnRNP-U and Characterization of Their Nucleic Acid Binding Activity
inferredcites →https://doi.org/10.1021/cr300513popenalex-snapshot
Transcription Factories: Genome Organization and Gene Regulation
inferredcites →https://doi.org/10.1038/emboj.2012.101openalex-snapshot
Co‐transcriptional degradation of aberrant pre‐mRNA by Xrn2
inferredcites →https://doi.org/10.1038/nature14443openalex-snapshot
The Xist lncRNA interacts with SHARP to silence transcription through HDAC3
inferredcites →https://doi.org/10.1038/ncomms5494openalex-snapshot
Retrieving the intracellular topology from multi-scale protein mobility mapping in living cells
inferredcites →https://doi.org/10.1038/nsmb.2509openalex-snapshot
Transcription forms and remodels supercoiling domains unfolding large-scale chromatin structures
inferredcites →https://doi.org/10.1038/s41467-022-31752-zopenalex-snapshot
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) safeguards the developing mouse cortex
inferredcites →https://doi.org/10.1038/s41556-022-00847-6openalex-snapshot
Spatial organization of transcribed eukaryotic genes
inferredcites →https://doi.org/10.1038/s41586-020-2077-3openalex-snapshot
A large-scale binding and functional map of human RNA-binding proteins
inferredcites →https://doi.org/10.1038/s41586-020-2308-7openalex-snapshot
The mutational constraint spectrum quantified from variation in 141,456 humans
inferredcites →https://doi.org/10.1038/s41586-021-04081-2openalex-snapshot
Cell-type specialization is encoded by specific chromatin topologies
inferredcites →https://doi.org/10.1073/pnas.1302950110openalex-snapshot
Nonspecific bridging-induced attraction drives clustering of DNA-binding proteins and genome organization
inferredcites →https://doi.org/10.1073/pnas.1414004111openalex-snapshot
Self-assembled FUS binds active chromatin and regulates gene transcription
inferredcites →https://doi.org/10.1073/pnas.1508461112openalex-snapshot
hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function
inferredcites →https://doi.org/10.1073/pnas.181342398openalex-snapshot
Electrostatics of nanosystems: Application to microtubules and the ribosome
inferredcites →https://doi.org/10.1073/pnas.2218085120openalex-snapshot
In diverse conditions, intrinsic chromatin condensates have liquid-like material properties
inferredcites →https://doi.org/10.1073/pnas.88.22.10312openalex-snapshot
Nuclear matrins: identification of the major nuclear matrix proteins.
inferredcites →https://doi.org/10.1073/pnas.94.9.4446openalex-snapshot
The nuclear matrix revealed by eluting chromatin from a cross-linked nucleus
inferredcites →https://doi.org/10.1074/mcp.m113.031591openalex-snapshot
Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ
inferredcites →https://doi.org/10.1083/jcb.200207115openalex-snapshot
Gene density and transcription influence the localization of chromatin outside of chromosome territories detectable by FISH
inferredcites →https://doi.org/10.1083/jcb.200303131openalex-snapshot
Clustering of multiple specific genes and gene-rich R-bands around SC-35 domains
inferredcites →https://doi.org/10.1083/jcb.201910148openalex-snapshot
Cell division requires RNA eviction from condensing chromosomes
inferredcites →https://doi.org/10.1083/jcb.202010003openalex-snapshot
Parameter-free molecular super-structures quantification in single-molecule localization microscopy
inferredcites →https://doi.org/10.1091/mbc.11.3.799openalex-snapshot
Half a Century of “The Nuclear Matrix”
inferredcites →https://doi.org/10.1091/mbc.e23-01-0004openalex-snapshot
Differential nuclear import regulates nuclear RNA inheritance following mitosis
inferredcites →https://doi.org/10.1093/bfgp/elz032openalex-snapshot
Bridging-induced microphase separation: photobleaching experiments, chromatin domains and the need for active reactions
inferredcites →https://doi.org/10.1093/bioinformatics/btu202openalex-snapshot
ThunderSTORM: a comprehensive ImageJ plug-in for PALM and STORM data analysis and super-resolution imaging
inferredcites →https://doi.org/10.1093/molbev/mst010openalex-snapshot
MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability
inferredcites →https://doi.org/10.1093/nar/gkaa1007openalex-snapshot
OMA orthology in 2021: website overhaul, conserved isoforms, ancestral gene order and more
inferredcites →https://doi.org/10.1093/nar/gkq712openalex-snapshot
Mapping of the nuclear matrix-bound chromatin hubs by a new M3C experimental procedure
inferredcites →https://doi.org/10.1093/nar/gks1441openalex-snapshot
Space exploration by the promoter of a long human gene during one transcription cycle
inferredcites →https://doi.org/10.1093/nar/gku698openalex-snapshot
Modeling epigenome folding: formation and dynamics of topologically associated chromatin domains
inferredcites →https://doi.org/10.1093/nar/gkv390openalex-snapshot
Dissecting the nascent human transcriptome by analysing the RNA content of transcription factories
inferredcites →https://doi.org/10.1093/nar/gkw135openalex-snapshot
Simulated binding of transcription factors to active and inactive regions folds human chromosomes into loops, rosettes and topological domains
inferredcites →https://doi.org/10.1093/nar/gkx460openalex-snapshot
Intrinsically disordered RGG/RG domains mediate degenerate specificity in RNA binding
inferredcites →https://doi.org/10.1093/nar/gky763openalex-snapshot
Transcription-driven genome organization: a model for chromosome structure and the regulation of gene expression tested through simulations
inferredcites →https://doi.org/10.1101/2022.06.09.495447openalex-snapshot
Gene structure heterogeneity drives transcription noise within human chromosomes
inferredcites →https://doi.org/10.1101/2023.07.22.550030openalex-snapshot
hnRNPUL1 ensures efficient Integrator-mediated cleavage of snRNAs and is mutated in amyotrophic lateral sclerosis
inferredcites →https://doi.org/10.1101/gad.292104openalex-snapshot
Chromatin decondensation and nuclear reorganization of the HoxB locus upon induction of transcription
inferredcites →https://doi.org/10.1101/gad.308528.117openalex-snapshot
Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity
inferredcites →https://doi.org/10.1101/gr.224576.117openalex-snapshot
The nuclear matrix protein HNRNPU maintains 3D genome architecture globally in mouse hepatocytes
inferredcites →https://doi.org/10.1103/physrevlett.126.228101openalex-snapshot
Interphase Chromatin Undergoes a Local Sol-Gel Transition upon Cell Differentiation
inferredcites →https://doi.org/10.1103/physrevx.6.041047openalex-snapshot
Polymer model with Epigenetic Recoloring Reveals a Pathway for the de novo Establishment and 3D Organization of Chromatin Domains
inferredcites →https://doi.org/10.1109/83.650848openalex-snapshot
A pyramid approach to subpixel registration based on intensity
inferredcites →https://doi.org/10.1126/sciadv.adf1488openalex-snapshot
Condensed but liquid-like domain organization of active chromatin regions in living human cells
inferredcites →https://doi.org/10.1126/science.1078694openalex-snapshot
Modulation of Heterochromatin Protein 1 Dynamics in Primary Mammalian Cells
inferredcites →https://doi.org/10.1126/science.1153529openalex-snapshot
Three-Dimensional Super-Resolution Imaging by Stochastic Optical Reconstruction Microscopy
inferredcites →https://doi.org/10.1126/science.1239053openalex-snapshot
Real-Time Dynamics of RNA Polymerase II Clustering in Live Human Cells
inferredcites →https://doi.org/10.1126/science.abi9810openalex-snapshot
Live-cell micromanipulation of a genomic locus reveals interphase chromatin mechanics
inferredcites →https://doi.org/10.1128/mcb.01312-14openalex-snapshot
Phosphorylation of SAF-A/hnRNP-U Serine 59 by Polo-Like Kinase 1 Is Required for Mitosis
inferredcites →https://doi.org/10.1128/mcb.24.14.6393-6402.2004openalex-snapshot
Global Nature of Dynamic Protein-Chromatin Interactions In Vivo: Three-Dimensional Genome Scanning and Dynamic Interaction Networks of Chromatin Proteins
inferredcites →https://doi.org/10.1134/s0006297911050014openalex-snapshot
Fluorescence correlation spectroscopy in biology, chemistry, and medicine
inferredcites →https://doi.org/10.1186/2043-9113-3-14openalex-snapshot
Plot protein: visualization of mutations
inferredcites →https://doi.org/10.1186/s13059-016-0909-0openalex-snapshot
Predicting the three-dimensional folding of cis-regulatory regions in mammalian genomes using bioinformatic data and polymer models
inferredcites →https://doi.org/10.1186/s13059-021-02350-xopenalex-snapshot
Intergenic RNA mainly derives from nascent transcripts of known genes
inferredcites →https://doi.org/10.1186/s13073-021-00870-6openalex-snapshot
Rare deleterious mutations of HNRNP genes result in shared neurodevelopmental disorders
inferredcites →https://doi.org/10.1242/bio.060113openalex-snapshot
Deficiency of the Heterogeneous Nuclear Ribonucleoprotein U locus leads to delayed hindbrain neurogenesis
inferredcites →https://doi.org/10.1242/jcs.114.3.463openalex-snapshot
Experimental observations of a nuclear matrix
inferredcites →https://doi.org/10.1242/jcs.258991openalex-snapshot
SAF-A promotes origin licensing and replication fork progression to ensure robust DNA replication
inferredcites →https://doi.org/10.1371/journal.pgen.1010952openalex-snapshot
Neurodevelopmental deficits and cell-type-specific transcriptomic perturbations in a mouse model of HNRNPU haploinsufficiency
inferredcites →https://doi.org/10.1371/journal.pone.0231450openalex-snapshot
Analysis of the nucleocytoplasmic shuttling RNA-binding protein HNRNPU using optimized HITS-CLIP method
inferredcites →https://doi.org/10.3390/biology3020320openalex-snapshot
On-Beads Digestion in Conjunction with Data-Dependent Mass Spectrometry: A Shortcut to Quantitative and Dynamic Interaction Proteomics
inferredcites →https://doi.org/10.3390/cells12151958openalex-snapshot
The Material Properties of the Cell Nucleus: A Matter of Scale
inferredcites →https://doi.org/10.7554/elife.47098openalex-snapshot
Evidence for DNA-mediated nuclear compartmentalization distinct from phase separation
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1002/ajmg.a.64013openalex-snapshot
Expanding the Phenotypic Spectrum of HNRNPU ‐Related Disorder, Documenting the First Familial Presentation and Comprehensive Review
inferred← citeshttps://doi.org/10.1016/j.ceb.2025.102561openalex-snapshot
Nuclear biophysics: Spatial coordination of transcriptional dynamics?
inferred← citeshttps://doi.org/10.1016/j.chembiol.2024.08.009openalex-snapshot
RNA and condensates: Disease implications and therapeutic opportunities
inferred← citeshttps://doi.org/10.1016/j.gde.2024.102304openalex-snapshot
Beyond equilibrium: roles of RNAs in condensate control
inferred← citeshttps://doi.org/10.1016/j.molcel.2024.08.021openalex-snapshot
An RNA-centric view of transcription and genome organization
inferred← citeshttps://doi.org/10.1016/j.sbi.2025.103136openalex-snapshot
Role of RNA in genome folding: It's all about affinity
inferred← citeshttps://doi.org/10.1016/j.xgen.2024.100698openalex-snapshot
Genome-wide chromosome architecture prediction reveals biophysical principles underlying gene structure
inferred← citeshttps://doi.org/10.1038/s44321-026-00440-6openalex-snapshot
HNRNPU and architectural lncRNAs as nuclear tethers of epithelial state stability
inferred← citeshttps://doi.org/10.1073/pnas.2603593123openalex-snapshot
How do RNA molecules distinguish self from non-self?
inferred← citeshttps://doi.org/10.1101/2024.09.09.612041openalex-snapshot
Role of the SAF-A SAP domain in X inactivation, transcription, splicing, and cell proliferation
inferred← citeshttps://doi.org/10.1101/2024.09.30.615666openalex-snapshot
Nucleoporin Nup153 docks the splicing machinery to the nuclear pore for efficient mRNA processing
inferred← citeshttps://doi.org/10.1111/nyas.15415openalex-snapshot
Chromatin‐associated condensates as an inspiration for the system architecture of future DNA computers
inferred← citeshttps://doi.org/10.1371/journal.pgen.1011719openalex-snapshot
Role of the SAF-A/HNRNPU SAP domain in X chromosome inactivation, nuclear dynamics, transcription, splicing, and cell proliferation
inferred← citeshttps://doi.org/10.64898/2025.12.15.694381openalex-snapshot
Role of the SAF-A/HNRNPU ATPase and RGG domains in X chromosome inactivation, nuclear dynamics, transcription, splicing, and cell proliferation
inferred← citeshttps://doi.org/10.64898/2026.06.09.731076openalex-snapshot
NANOG assembles into self-limiting aging micelles that drive a sol-gel transition and modulate DNA dynamics
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