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Cerebral Microvascular Density, Permeability of the Blood-Brain Barrier, and Neuroinflammatory Responses Indicate Early Aging Characteristics in a Marfan Syndrome Mouse Model
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Transforming growth factor‐β stimulates β amyloid uptake by microglia through Smad3‐dependent mechanisms
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Measurements of cerebral microvascular blood flow, oxygenation, and morphology in a mouse model of whole-brain irradiation-induced cognitive impairment by two-photon microscopy and optical coherence tomography: evidence for microvascular injury in the cerebral white matter
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MMP-2 Is Mainly Expressed in Arterioles and Contributes to Cerebral Vascular Remodeling Associated with TGF-β1 Signaling
inferredcites →https://doi.org/10.1016/j.ajpath.2017.11.006openalex-snapshot
Inhibition of Marfan Syndrome Aortic Root Dilation by Losartan
inferredcites →https://doi.org/10.1016/j.arr.2024.102224openalex-snapshot
Unveiling the impact of aging on BBB and Alzheimer's disease: Factors and therapeutic implications
inferredcites →https://doi.org/10.1016/j.bbi.2013.12.018openalex-snapshot
Age-dependent changes on TGFβ1 Smad3 pathway modify the pattern of microglial cell activation
inferredcites →https://doi.org/10.1016/j.brainresbull.2023.110810openalex-snapshot
Inhibition of MMP-2 and MMP-9 attenuates surgery-induced cognitive impairment in aged mice
inferredcites →https://doi.org/10.1016/j.cccb.2024.100216openalex-snapshot
Fluid biomarkers of the neurovascular unit in cerebrovascular disease and vascular cognitive disorders: A systematic review and meta-analysis
inferredcites →https://doi.org/10.1016/j.expneurol.2020.113257openalex-snapshot
Brain injury-induced dysfunction of the blood brain barrier as a risk for dementia
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2018.02.023openalex-snapshot
Redox stress in Marfan syndrome: Dissecting the role of the NADPH oxidase NOX4 in aortic aneurysm
inferredcites →https://doi.org/10.1016/j.ijdevneu.2005.04.001openalex-snapshot
Emerging roles for TGF‐β1 in nervous system development
inferredcites →https://doi.org/10.1016/j.jpeds.2018.08.061openalex-snapshot
Health-Related Quality of Life in Children and Young Adults with Marfan Syndrome
inferredcites →https://doi.org/10.1016/j.jsb.2014.07.003openalex-snapshot
Quantification of aortic and cutaneous elastin and collagen morphology in Marfan syndrome by multiphoton microscopy
inferredcites →https://doi.org/10.1016/j.matbio.2015.05.002openalex-snapshot
The fibrillin microfibril scaffold: A niche for growth factors and mechanosensation?
inferredcites →https://doi.org/10.1016/j.mric.2024.01.003openalex-snapshot
Basic Science of Neuroinflammation and Involvement of the Inflammatory Response in Disorders of the Nervous System
inferredcites →https://doi.org/10.1016/j.neuint.2021.104982openalex-snapshot
The effect of aged microglia on synaptic impairment and its relevance in neurodegenerative diseases
inferredcites →https://doi.org/10.1016/j.neuroscience.2015.03.023openalex-snapshot
Fibrillin-1 impairment enhances blood–brain barrier permeability and xanthoma formation in brains of apolipoprotein E-deficient mice
inferredcites →https://doi.org/10.1023/a:1007034003114openalex-snapshot
Immunogold study of regional differences in the distribution of glucose transporter (GLUT-1) in mouse brain associated with physiological and accelerated aging and scrapie infection
inferredcites →https://doi.org/10.1023/a:1011995308851openalex-snapshot
Effect of a single embryonic exposure to alcohol on glucose transporter (GLUT-1) distribution in brain vessels of aged mouse
inferredcites →https://doi.org/10.1038/labinvest.2011.124openalex-snapshot
TGF-β signaling in endothelial cells, but not neuroepithelial cells, is essential for cerebral vascular development
inferredcites →https://doi.org/10.1038/nrcardio.2010.30openalex-snapshot
Marfan syndrome. Part 1: pathophysiology and diagnosis
inferredcites →https://doi.org/10.1038/nrcardio.2010.31openalex-snapshot
Marfan syndrome. Part 2: treatment and management of patients
inferredcites →https://doi.org/10.1038/s41419-021-04004-zopenalex-snapshot
TGF-β1-mediated exosomal lnc-MMP2-2 increases blood–brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis
inferredcites →https://doi.org/10.1038/s41598-020-64071-8openalex-snapshot
Characterization of doxycycline-mediated inhibition of Marfan syndrome-associated aortic dilation by multiphoton microscopy
inferredcites →https://doi.org/10.1038/s41598-024-56438-yopenalex-snapshot
In vivo phenotypic vascular dysfunction extends beyond the aorta in a mouse model for fibrillin-1 (Fbn1) mutation
inferredcites →https://doi.org/10.1038/sj.bjp.0707181openalex-snapshot
Endothelial dysfunction and compromised eNOS/Akt signaling in the thoracic aorta during the progression of Marfan syndrome
inferredcites →https://doi.org/10.1097/wco.0000000000000248openalex-snapshot
Blood−brain barrier breakdown and neovascularization processes after stroke and traumatic brain injury
inferredcites →https://doi.org/10.1111/j.1365-2990.2010.01139.xopenalex-snapshot
Review: Cerebral microvascular pathology in ageing and neurodegeneration
inferredcites →https://doi.org/10.1111/j.1476-5381.2009.00439.xopenalex-snapshot
Dysfunction of endothelial and smooth muscle cells in small arteries of a mouse model of Marfan syndrome
inferredcites →https://doi.org/10.1111/j.1749-6632.2010.05786.xopenalex-snapshot
Aging and cerebrovascular dysfunction: contribution of hypertension, cerebral amyloid angiopathy, and immunotherapy
inferredcites →https://doi.org/10.1111/jnc.14860openalex-snapshot
Microglia and the aging brain: are senescent microglia the key to neurodegeneration?
inferredcites →https://doi.org/10.1139/y92-252openalex-snapshot
Changes in the glucose transporter of brain capillaries
inferredcites →https://doi.org/10.1152/japplphysiol.00132.2017openalex-snapshot
Mild aerobic exercise blocks elastin fiber fragmentation and aortic dilatation in a mouse model of Marfan syndrome associated aortic aneurysm
inferredcites →https://doi.org/10.1159/000096351openalex-snapshot
Matrix Metalloproteinases and Atherogenesis in Dependence of Age
inferredcites →https://doi.org/10.1161/circresaha.107.157776openalex-snapshot
Loss of Elastic Fiber Integrity and Reduction of Vascular Smooth Muscle Contraction Resulting From the Upregulated Activities of Matrix Metalloproteinase-2 and -9 in the Thoracic Aortic Aneurysm in Marfan Syndrome
inferredcites →https://doi.org/10.1161/res.90.3.251openalex-snapshot
Matrix Metalloproteinases in Vascular Remodeling and Atherogenesis
inferredcites →https://doi.org/10.1161/strokeaha.122.036946openalex-snapshot
Neuroinflammation, Stroke, Blood-Brain Barrier Dysfunction, and Imaging Modalities
inferredcites →https://doi.org/10.1177/002215549904700806openalex-snapshot
Quantitative Immunocytochemical Study of Blood-Brain Barrier Glucose Transporter (GLUT-1) in Four Regions of Mouse Brain
inferredcites →https://doi.org/10.1177/0271678x16655551openalex-snapshot
Matrix metalloproteinases in the brain and blood–brain barrier: Versatile breakers and makers
inferredcites →https://doi.org/10.1177/0271678x221076557openalex-snapshot
Assessment of microvascular rarefaction in human brain disorders using physiological magnetic resonance imaging
inferredcites →https://doi.org/10.1186/1479-5876-10-183openalex-snapshot
TGF-β – an excellent servant but a bad master
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Elevated circulating TGFβ1 during acute liver failure activates TGFβR2 on cortical neurons and exacerbates neuroinflammation and hepatic encephalopathy in mice
inferredcites →https://doi.org/10.1186/s12987-020-00197-1openalex-snapshot
Inhibition of transforming growth factor beta signaling pathway promotes differentiation of human induced pluripotent stem cell-derived brain microvascular endothelial-like cells
inferredcites →https://doi.org/10.14336/ad.2023.1225openalex-snapshot
Aging Increases Hypoxia-Induced Endothelial Permeability and Blood-Brain Barrier Dysfunction by Upregulating Arginase-II
inferredcites →https://doi.org/10.1517/14728222.2014.957672openalex-snapshot
MMPs: a novel drug target for schizophrenia
inferredcites →https://doi.org/10.21037/cdt-20-692openalex-snapshot
Quality of life in patients with Marfan syndrome: a cross-sectional study of 102 adult patients
inferredcites →https://doi.org/10.3233/jad-230792openalex-snapshot
Effect of Vascular Risk Factors on Blood-Brain Barrier and Cerebrospinal Fluid Biomarkers Along the Alzheimer’s Disease Continuum: A Retrospective Observational Study
inferredcites →https://doi.org/10.3389/fneur.2020.00946openalex-snapshot
Sex-Dependent Pathology in the HPA Axis at a Sub-acute Period After Experimental Traumatic Brain Injury
inferredcites →https://doi.org/10.3389/fnins.2019.01434openalex-snapshot
Experimental Traumatic Brain Injury Induces Chronic Glutamatergic Dysfunction in Amygdala Circuitry Known to Regulate Anxiety-Like Behavior
inferredcites →https://doi.org/10.3389/fphys.2017.00933openalex-snapshot
Differences in the Thoracic Aorta by Region and Sex in a Murine Model of Marfan Syndrome
inferredcites →https://doi.org/10.3389/fphys.2020.584891openalex-snapshot
Cerebrovascular Blood Flow Design and Regulation; Vulnerability in Aging Brain
inferredcites →https://doi.org/10.3390/ijms23010438openalex-snapshot
Multi-Omics Profiling in Marfan Syndrome: Further Insights into the Molecular Mechanisms Involved in Aortic Disease
inferredcites →https://doi.org/10.5603/cj.2013.0066openalex-snapshot
The role of transforming growth factor-beta in Marfan syndrome
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1101/2024.10.14.618278openalex-snapshot
Apoptosis is Increased in Cortical Neurons of Female Marfan Syndrome Mice
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