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Identification of a broad and potent V3 glycan site bNAb targeting an N332 gp120 glycan-independent epitope

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Effect of Breastfeeding and Formula Feeding on Transmission of HIV-1
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Evaluating Neutralizing Antibodies Against HIV, SIV, and SHIV in Luciferase Reporter Gene Assays
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By‐products of immunoglobulin somatic hypermutation
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UCSF ChimeraX : Structure visualization for researchers, educators, and developers
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UCSF ChimeraX : Tools for structure building and analysis
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Measuring HIV Neutralization in a Luciferase Reporter Gene Assay
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Evaluation of susceptibility of HIV-1 CRF01_AE variants to neutralization by a panel of broadly neutralizing antibodies
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Antibody responses to the HIV-1 envelope high mannose patch
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Next-generation bNAbs for HIV-1 cure strategies
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Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies
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Sequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice
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Identification of Near-Pan-neutralizing Antibodies against HIV-1 by Deconvolution of Plasma Humoral Responses
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Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody
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Longitudinal Isolation of Potent Near-Germline SARS-CoV-2-Neutralizing Antibodies from COVID-19 Patients
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A pseudovirus system enables deep mutational scanning of the full SARS-CoV-2 spike
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Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates
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Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies
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Bivalent intra-spike binding provides durability against emergent Omicron lineages: Results from a global consortium
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Harnessing Avidity: Quantifying the Entropic and Energetic Effects of Linker Length and Rigidity for Multivalent Binding of Antibodies to HIV-1
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Mapping the neutralizing specificity of human anti-HIV serum by deep mutational scanning
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Anti-V1/V3-glycan broadly HIV-1 neutralizing antibodies in a post-treatment controller
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The potential of engineered antibodies for HIV-1 therapy and cure
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Broadly neutralizing antibodies against HIV-1 and concepts for application
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HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies
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Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth
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A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope
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HIV-1 Vaccines Based on Antibody Identification, B Cell Ontogeny, and Epitope Structure
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Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope
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Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes
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Glycan Positioning Impacts HIV-1 Env Glycan-Shield Density, Function, and Recognition by Antibodies
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Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning
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Optimization and validation of the TZM-bl assay for standardized assessments of neutralizing antibodies against HIV-1
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openPrimeR for multiplex amplification of highly diverse templates
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Automated electron microscope tomography using robust prediction of specimen movements
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RELION: Implementation of a Bayesian approach to cryo-EM structure determination
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Model Building and Refinement of a Natively Glycosylated HIV-1 Env Protein by High-Resolution Cryoelectron Microscopy
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A robust heterodimeric Fc platform engineered for efficient development of bispecific antibodies of multiple formats
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Contrasting IgG Structures Reveal Extreme Asymmetry and Flexibility
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Location and length distribution of somatic hypermutation-associated DNA insertions and deletions reveals regions of antibody structural plasticity
inferredcites →https://doi.org/10.1038/nature09385openalex-snapshot
Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation
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Broad neutralization coverage of HIV by multiple highly potent antibodies
inferredcites →https://doi.org/10.1038/nature11604openalex-snapshot
HIV therapy by a combination of broadly neutralizing antibodies in humanized mice
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Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia
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Structure and immune recognition of trimeric pre-fusion HIV-1 Env
inferredcites →https://doi.org/10.1038/nature14411openalex-snapshot
Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117
inferredcites →https://doi.org/10.1038/nature18929openalex-snapshot
HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption
inferredcites →https://doi.org/10.1038/nature23010openalex-snapshot
Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike
inferredcites →https://doi.org/10.1038/nbt.1601openalex-snapshot
Enhanced antibody half-life improves in vivo activity
inferredcites →https://doi.org/10.1038/nm.3565openalex-snapshot
Early development of broadly neutralizing antibodies in HIV-1–infected infants
inferredcites →https://doi.org/10.1038/nm.4268openalex-snapshot
Antibody 10-1074 suppresses viremia in HIV-1-infected individuals
inferredcites →https://doi.org/10.1038/nmeth.4169openalex-snapshot
cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination
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Sequencing and cloning of antigen-specific antibodies from mouse memory B cells
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Passive immunotherapy of viral infections: 'super-antibodies' enter the fray
inferredcites →https://doi.org/10.1038/nsmb.2594openalex-snapshot
Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120
inferredcites →https://doi.org/10.1038/nsmb.3051openalex-snapshot
Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env
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Privateer: software for the conformational validation of carbohydrate structures
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Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site
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Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies
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Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope
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Kappa chain maturation helps drive rapid development of an infant HIV-1 broadly neutralizing antibody lineage
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Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer
inferredcites →https://doi.org/10.1038/s41467-023-42906-yopenalex-snapshot
Probabilities of developing HIV-1 bNAb sequence features in uninfected and chronically infected individuals
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Exploring distinct modes of inter-spike cross-linking for enhanced neutralization by SARS-CoV-2 antibodies
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Cryo-ET of IgG bivalent binding on SARS-CoV-2 provides structural basis for antibody avidity
inferredcites →https://doi.org/10.1038/s41541-024-01038-0openalex-snapshot
Neutralizing antibodies elicited in macaques recognize V3 residues on altered conformations of HIV-1 Env trimer
inferredcites →https://doi.org/10.1038/s41577-022-00753-wopenalex-snapshot
Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies
inferredcites →https://doi.org/10.1038/s41586-018-0531-2openalex-snapshot
Combination therapy with anti-HIV-1 antibodies maintains viral suppression
inferredcites →https://doi.org/10.1038/s41586-019-1250-zopenalex-snapshot
Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques
inferredcites →https://doi.org/10.1038/s41586-020-2852-1openalex-snapshot
SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies
inferredcites →https://doi.org/10.1038/s41590-018-0235-7openalex-snapshot
Recent progress in broadly neutralizing antibodies to HIV
inferredcites →https://doi.org/10.1038/s41591-018-0186-4openalex-snapshot
Safety and antiviral activity of combination HIV-1 broadly neutralizing antibodies in viremic individuals
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Broadly neutralizing anti-HIV-1 monoclonal antibodies in the clinic
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Safety and antiviral activity of triple combination broadly neutralizing monoclonal antibody therapy against HIV-1: a phase 1 clinical trial
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Neutralization titer biomarker for antibody-mediated prevention of HIV-1 acquisition
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Dynamics and durability of HIV-1 neutralization are determined by viral replication
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Safety and antiviral effect of a triple combination of HIV-1 broadly neutralizing antibodies: a phase 1/2a trial
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Non-uniform refinement: adaptive regularization improves single-particle cryo-EM reconstruction
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Effective high-throughput isolation of fully human antibodies targeting infectious pathogens
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New tools for automated cryo-EM single-particle analysis in RELION-4.0
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Two Randomized Trials of Neutralizing Antibodies to Prevent HIV-1 Acquisition
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Crystal structure of the human T cell receptor CD3εγ heterodimer complexed to the therapeutic mAb OKT3
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Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies
inferredcites →https://doi.org/10.1073/pnas.1208984109openalex-snapshot
Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120
inferredcites →https://doi.org/10.1073/pnas.1217207109openalex-snapshot
Complex-type N -glycan recognition by potent broadly neutralizing HIV antibodies
inferredcites →https://doi.org/10.1073/pnas.1309215110openalex-snapshot
Computational analysis of anti–HIV-1 antibody neutralization panel data to identify potential functional epitope residues
inferredcites →https://doi.org/10.1073/pnas.1315295110openalex-snapshot
HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice
inferredcites →https://doi.org/10.1073/pnas.1415789111openalex-snapshot
Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex
inferredcites →https://doi.org/10.1080/14728222.2020.1752183openalex-snapshot
Targeting the N332-supersite of the HIV-1 envelope for vaccine design
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Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies
inferredcites →https://doi.org/10.1084/jem.20130221openalex-snapshot
Restricting HIV-1 pathways for escape using rationally designed anti–HIV-1 antibodies
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ARMADiLLO: a web server for analyzing antibody mutation probabilities
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IgBLAST: an immunoglobulin variable domain sequence analysis tool
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CATNAP: a tool to compile, analyze and tally neutralizing antibody panels
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A biophysical model of viral escape from polyclonal antibodies
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HIV broadly neutralizing antibody targets
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Divide and conquer: broadly neutralizing antibody combinations for improved HIV-1 viral coverage
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Features and development of Coot
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X-ray and EM structures of a natively glycosylated HIV-1 envelope trimer
inferredcites →https://doi.org/10.1107/s2059798318005119openalex-snapshot
Structural analysis of glycoproteins: building N-linked glycans withCoot
inferredcites →https://doi.org/10.1107/s2059798318006551openalex-snapshot
Real-space refinement in PHENIX for cryo-EM and crystallography
inferredcites →https://doi.org/10.1111/imr.12507openalex-snapshot
The HIV ‐1 envelope glycoprotein structure: nailing down a moving target
inferredcites →https://doi.org/10.1126/science.1093933openalex-snapshot
Development of a Human Adaptive Immune System in Cord Blood Cell-Transplanted Mice
inferredcites →https://doi.org/10.1126/science.1111781openalex-snapshot
Cardiolipin Polyspecific Autoreactivity in Two Broadly Neutralizing HIV-1 Antibodies
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Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1
inferredcites →https://doi.org/10.1126/science.1207227openalex-snapshot
Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding
inferredcites →https://doi.org/10.1126/science.1213256openalex-snapshot
A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield
inferredcites →https://doi.org/10.1126/science.aax4380openalex-snapshot
A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses
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Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates
inferredcites →https://doi.org/10.1126/scitranslmed.aad5752openalex-snapshot
Virologic effects of broadly neutralizing antibody VRC01 administration during chronic HIV-1 infection
inferredcites →https://doi.org/10.1126/scitranslmed.aai7514openalex-snapshot
Staged induction of HIV-1 glycan–dependent broadly neutralizing antibodies
inferredcites →https://doi.org/10.1126/scitranslmed.aal2144openalex-snapshot
Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller
inferredcites →https://doi.org/10.1126/scitranslmed.abk1533openalex-snapshot
Sequential immunization of macaques elicits heterologous neutralizing antibodies targeting the V3-glycan patch of HIV-1 Env
inferredcites →https://doi.org/10.1128/jvi.00195-25openalex-snapshot
Comprehensive maps of escape mutations from antibodies 10-1074 and 3BNC117 for Envs from two divergent HIV strains
inferredcites →https://doi.org/10.1128/jvi.02108-09openalex-snapshot
Tiered Categorization of a Diverse Panel of HIV-1 Env Pseudoviruses for Assessment of Neutralizing Antibodies
inferredcites →https://doi.org/10.1128/jvi.02652-15openalex-snapshot
Structure-Guided Redesign Increases the Propensity of HIV Env To Generate Highly Stable Soluble Trimers
inferredcites →https://doi.org/10.1128/jvi.02660-07openalex-snapshot
Deciphering Human Immunodeficiency Virus Type 1 Transmission and Early Envelope Diversification by Single-Genome Amplification and Sequencing
inferredcites →https://doi.org/10.1128/jvi.02853-13openalex-snapshot
Global Panel of HIV-1 Env Reference Strains for Standardized Assessments of Vaccine-Elicited Neutralizing Antibodies
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Human Immunodeficiency Virus Type 1 env Clones from Acute and Early Subtype B Infections for Standardized Assessments of Vaccine-Elicited Neutralizing Antibodies
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Broadly Neutralizing Antibodies to HIV and Their Role in Vaccine Design
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New-Generation High-Potency and Designer Antibodies: Role in HIV-1 Treatment
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Mechanisms of escape from the PGT128 family of anti-HIV broadly neutralizing antibodies
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Few and Far Between: How HIV May Be Evading Antibody Avidity
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A Limited Number of Antibody Specificities Mediate Broad and Potent Serum Neutralization in Selected HIV-1 Infected Individuals
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A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies
inferredcites →https://doi.org/10.1371/journal.ppat.1005369openalex-snapshot
Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort
inferredcites →https://doi.org/10.1371/journal.ppat.1005520openalex-snapshot
Optimal Combinations of Broadly Neutralizing Antibodies for Prevention and Treatment of HIV-1 Clade C Infection
inferredcites →https://doi.org/10.1371/journal.ppat.1006148openalex-snapshot
Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting
inferredcites →https://doi.org/10.1371/journal.ppat.1007920openalex-snapshot
Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics
inferredcites →https://doi.org/10.3389/fimmu.2021.712122openalex-snapshot
Broadly Neutralizing Antibodies for HIV-1 Prevention
inferredcites →https://doi.org/10.3390/biom5042919openalex-snapshot
Engineering and Characterization of a Fluorescent Native-Like HIV-1 Envelope Glycoprotein Trimer
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AbRAT: The Antibody Repertoire Analysis Toolkit

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Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1101/2025.10.06.680687openalex-snapshot
Consistent Induction of Broadly Neutralizing HIV Antibodies by a Novel Two-Step Mechanism Informs Immunogen Design
inferred← citeshttps://doi.org/10.1101/2025.10.29.685411openalex-snapshot
VRC01 Selects Rare HIV Escape Mutations After Acquisition in Antibody-Mediated Prevention Trials
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