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Leveraging heterogeneity across multiple data sets increases accuracy of cell-mixture deconvolution and reduces biological and technical biases
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1016/j.coi.2013.09.015openalex-snapshot
Computational deconvolution: extracting cell type-specific information from heterogeneous samples
inferredcites →https://doi.org/10.1016/j.immuni.2015.11.003openalex-snapshot
Integrated, Multi-cohort Analysis Identifies Conserved Transcriptional Signatures across Multiple Respiratory Viruses
inferredcites →https://doi.org/10.1016/j.jesp.2013.03.013openalex-snapshot
Detecting outliers: Do not use standard deviation around the mean, use absolute deviation around the median
inferredcites →https://doi.org/10.1016/s2213-2600(16)00048-5openalex-snapshot
Genome-wide expression for diagnosis of pulmonary tuberculosis: a multicohort analysis
inferredcites →https://doi.org/10.1038/nature13320openalex-snapshot
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer
inferredcites →https://doi.org/10.1038/nbt0410-322openalex-snapshot
A global map of human gene expression
inferredcites →https://doi.org/10.1038/nm.3909openalex-snapshot
The prognostic landscape of genes and infiltrating immune cells across human cancers
inferredcites →https://doi.org/10.1038/nm.4267openalex-snapshot
Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states
inferredcites →https://doi.org/10.1038/nmeth.1439openalex-snapshot
Cell type–specific gene expression differences in complex tissues
inferredcites →https://doi.org/10.1038/nmeth.1710openalex-snapshot
Population-specific expression analysis (PSEA) reveals molecular changes in diseased brain
inferredcites →https://doi.org/10.1038/nmeth.3337openalex-snapshot
Robust enumeration of cell subsets from tissue expression profiles
inferredcites →https://doi.org/10.1038/sj.gene.6364173openalex-snapshot
Immune response in silico (IRIS): immune-specific genes identified from a compendium of microarray expression data
inferredcites →https://doi.org/10.1084/jem.20122709openalex-snapshot
A common rejection module (CRM) for acute rejection across multiple organs identifies novel therapeutics for organ transplantation
inferredcites →https://doi.org/10.1093/bioinformatics/17.suppl_1.s279openalex-snapshot
Separation of samples into their constituents using gene expression data
inferredcites →https://doi.org/10.1093/bioinformatics/btt351openalex-snapshot
CellMix: a comprehensive toolbox for gene expression deconvolution
inferredcites →https://doi.org/10.1093/nar/gkw797openalex-snapshot
Methods to increase reproducibility in differential gene expression via meta-analysis
inferredcites →https://doi.org/10.1126/scitranslmed.aaa5993openalex-snapshot
A comprehensive time-course–based multicohort analysis of sepsis and sterile inflammation reveals a robust diagnostic gene set
inferredcites →https://doi.org/10.1126/scitranslmed.aaf7165openalex-snapshot
Robust classification of bacterial and viral infections via integrated host gene expression diagnostics
inferredcites →https://doi.org/10.1142/9789813207813_0015openalex-snapshot
EMPOWERING MULTI-COHORT GENE EXPRESSION ANALYSIS TO INCREASE REPRODUCIBILITY
inferredcites →https://doi.org/10.1158/0008-5472.can-13-2775openalex-snapshot
A Meta-analysis of Lung Cancer Gene Expression Identifies PTK7 as a Survival Gene in Lung Adenocarcinoma
inferredcites →https://doi.org/10.1172/jci.insight.89073openalex-snapshot
Integrated, multicohort analysis of systemic sclerosis identifies robust transcriptional signature of disease severity
inferredcites →https://doi.org/10.1186/s40478-014-0093-yopenalex-snapshot
Integrated multi-cohort transcriptional meta-analysis of neurodegenerative diseases
inferredcites →https://doi.org/10.1371/journal.pone.0006098openalex-snapshot
Deconvolution of Blood Microarray Data Identifies Cellular Activation Patterns in Systemic Lupus Erythematosus
inferredcites →https://doi.org/10.1371/journal.pone.0027156openalex-snapshot
Optimal Deconvolution of Transcriptional Profiling Data Using Quadratic Programming with Application to Complex Clinical Blood Samples
inferredcites →https://doi.org/10.18632/aging.100720openalex-snapshot
Aging-dependent alterations in gene expression and a mitochondrial signature of responsiveness to human influenza vaccination
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1016/j.celrep.2019.01.041openalex-snapshot
RNA-Seq Signatures Normalized by mRNA Abundance Allow Absolute Deconvolution of Human Immune Cell Types
inferred← citeshttps://doi.org/10.1038/s41467-019-10387-7openalex-snapshot
Mass cytometry reveals systemic and local immune signatures that distinguish inflammatory bowel diseases
inferred← citeshttps://doi.org/10.1038/s41586-018-0439-xopenalex-snapshot
A multi-cohort study of the immune factors associated with M. tuberculosis infection outcomes
inferred← citeshttps://doi.org/10.1101/834093openalex-snapshot
A Unified Molecular Signature of Systemic Lupus Erythematosus Revealed by Integrated, Multi-Cohort Transcriptomic Analysis
inferred← citeshttps://doi.org/10.1109/bibm.2017.8217875openalex-snapshot
Complementing single-cell RNA-seq using bulk transcriptional profiles
inferred← citeshttps://doi.org/10.1126/scitranslmed.aaw4974openalex-snapshot
Cellular senescence impairs the reversibility of pulmonary arterial hypertension
inferred← citeshttps://doi.org/10.1172/jci.insight.122312openalex-snapshot
Integrated, multicohort analysis reveals unified signature of systemic lupus erythematosus
inferred← citeshttps://doi.org/10.1186/s13073-018-0554-1openalex-snapshot
KLRD1-expressing natural killer cells predict influenza susceptibility
inferred← citeshttps://doi.org/10.3410/f.733846436.793565366openalex-snapshot
Faculty Opinions recommendation of A multi-cohort study of the immune factors associated with M. tuberculosis infection outcomes.
inferred← citeshttps://doi.org/10.3410/f.735001574.793559769openalex-snapshot
Faculty Opinions recommendation of RNA-Seq Signatures Normalized by mRNA Abundance Allow Absolute Deconvolution of Human Immune Cell Types.
inferred← citeshttps://doi.org/10.3410/f.736010848.793561991openalex-snapshot
Faculty Opinions recommendation of Mass cytometry reveals systemic and local immune signatures that distinguish inflammatory bowel diseases.
inferred← citeshttps://doi.org/10.70675/ba480b3dze0c8z442dz9b9czc363d3107e66openalex-snapshot
Unsupervised deconvolution of bulk omics profiles : methodology and application to characterize the immune landscape in tumors
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