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Penetrance of polygenic obesity susceptibility loci across the body mass index distribution: an update on scaling effects
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Association of a Genetic Risk Score With Body Mass Index Across Different Birth Cohorts
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The Disease Burden Associated With Overweight and Obesity
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Analysis of Gene‐Gene Interactions
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An Empirical Comparison of Meta‐analysis and Mega‐analysis of Individual Participant Data for Identifying Gene‐Environment Interactions
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HIGHLIGHTING DIFFERENCES BETWEEN CONDITIONAL AND UNCONDITIONAL QUANTILE REGRESSION APPROACHES THROUGH AN APPLICATION TO ASSESS MEDICATION ADHERENCE
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Obesity-susceptibility loci and the tails of the pediatric BMI distribution
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How should meta‐regression analyses be undertaken and interpreted?
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Quality Control for Genome-Wide Association Studies
inferredcites →https://doi.org/10.1007/s10519-009-9281-0openalex-snapshot
Rank-Based Inverse Normal Transformations are Increasingly Used, But are They Merited?
inferredcites →https://doi.org/10.1016/j.ajhg.2010.11.007openalex-snapshot
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height
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GCTA: A Tool for Genome-wide Complex Trait Analysis
inferredcites →https://doi.org/10.1016/j.ajhg.2011.12.022openalex-snapshot
Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci
inferredcites →https://doi.org/10.1016/j.ajhg.2013.10.005openalex-snapshot
Inference of the Genetic Architecture Underlying BMI and Height with the Use of 20,240 Sibling Pairs
inferredcites →https://doi.org/10.1016/s0140-6736(11)60814-3openalex-snapshot
Health and economic burden of the projected obesity trends in the USA and the UK
inferredcites →https://doi.org/10.1017/s0007114511007410openalex-snapshot
Association of the fat mass and obesity-associated (FTO) gene variant (rs9939609) with dietary intake in the Finnish Diabetes Prevention Study
inferredcites →https://doi.org/10.1038/mp.2011.45openalex-snapshot
Depressive disorder moderates the effect of the FTO gene on body mass index
inferredcites →https://doi.org/10.1038/nature05616openalex-snapshot
A genome-wide association study identifies novel risk loci for type 2 diabetes
inferredcites →https://doi.org/10.1038/nature11401openalex-snapshot
FTO genotype is associated with phenotypic variability of body mass index
inferredcites →https://doi.org/10.1038/nature14177openalex-snapshot
Genetic studies of body mass index yield new insights for obesity biology
inferredcites →https://doi.org/10.1038/nature15393openalex-snapshot
A global reference for human genetic variation
inferredcites →https://doi.org/10.1038/ncomms12724openalex-snapshot
Multiple novel gene-by-environment interactions modify the effect of FTO variants on body mass index
inferredcites →https://doi.org/10.1038/ng.177openalex-snapshot
Common nonsynonymous variants in PCSK1 confer risk of obesity
inferredcites →https://doi.org/10.1038/ng.2213openalex-snapshot
Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits
inferredcites →https://doi.org/10.1038/ng.2606openalex-snapshot
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
inferredcites →https://doi.org/10.1038/ng.269openalex-snapshot
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
inferredcites →https://doi.org/10.1038/ng.274openalex-snapshot
Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity
inferredcites →https://doi.org/10.1038/ng.3097openalex-snapshot
Defining the role of common variation in the genomic and biological architecture of adult human height
inferredcites →https://doi.org/10.1038/ng.3390openalex-snapshot
Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index
inferredcites →https://doi.org/10.1038/ng.3401openalex-snapshot
Population genetic differentiation of height and body mass index across Europe
inferredcites →https://doi.org/10.1038/ng.686openalex-snapshot
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
inferredcites →https://doi.org/10.1038/nprot.2010.116openalex-snapshot
Data quality control in genetic case-control association studies
inferredcites →https://doi.org/10.1038/nrg2579openalex-snapshot
Detecting gene–gene interactions that underlie human diseases
inferredcites →https://doi.org/10.1038/srep18672openalex-snapshot
Physical activity and genetic predisposition to obesity in a multiethnic longitudinal study
inferredcites →https://doi.org/10.1042/cs20160136openalex-snapshot
Recent progress in genetics, epigenetics and metagenomics unveils the pathophysiology of human obesity
inferredcites →https://doi.org/10.1042/cs20160221openalex-snapshot
The importance of gene–environment interactions in human obesity
inferredcites →https://doi.org/10.1056/nejm199005243222102openalex-snapshot
The Body-Mass Index of Twins Who Have Been Reared Apart
inferredcites →https://doi.org/10.1080/01621459.1999.10473882openalex-snapshot
Goodness of Fit and Related Inference Processes for Quantile Regression
inferredcites →https://doi.org/10.1080/01621459.2015.1008101openalex-snapshot
Quantile Regression in the Secondary Analysis of Case–Control Data
inferredcites →https://doi.org/10.1086/429864openalex-snapshot
A Note on Exact Tests of Hardy-Weinberg Equilibrium
inferredcites →https://doi.org/10.1086/519795openalex-snapshot
PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses
inferredcites →https://doi.org/10.1093/ajcn/87.2.398openalex-snapshot
Evidence for a strong genetic influence on childhood adiposity despite the force of the obesogenic environment
inferredcites →https://doi.org/10.1093/aje/kwr008openalex-snapshot
Influence of Physical Inactivity on Associations Between Single Nucleotide Polymorphisms and Genetic Predisposition to Childhood Obesity
inferredcites →https://doi.org/10.1093/bioinformatics/btm108openalex-snapshot
GenABEL: an R library for genome-wide association analysis
inferredcites →https://doi.org/10.1093/hmg/dds396openalex-snapshot
Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals
inferredcites →https://doi.org/10.1093/hmg/ddu411openalex-snapshot
FTO genetic variants, dietary intake and body mass index: insights from 177 330 individuals
inferredcites →https://doi.org/10.1093/hmg/ddw433openalex-snapshot
Quantifying the extent to which index event biases influence large genetic association studies
inferredcites →https://doi.org/10.1093/hmg/ddx062openalex-snapshot
Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels
inferredcites →https://doi.org/10.1093/ije/dyw337openalex-snapshot
Gene–obesogenic environment interactions in the UK Biobank study
inferredcites →https://doi.org/10.1093/nar/gkw1133openalex-snapshot
The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog)
inferredcites →https://doi.org/10.1097/gim.0b013e31812eece0openalex-snapshot
The impact of genotype frequencies on the clinical validity of genomic profiling for predicting common chronic diseases
inferredcites →https://doi.org/10.1126/science.1142358openalex-snapshot
Genome-Wide Association Analysis Identifies Loci for Type 2 Diabetes and Triglyceride Levels
inferredcites →https://doi.org/10.1126/science.280.5368.1371openalex-snapshot
Environmental Contributions to the Obesity Epidemic
inferredcites →https://doi.org/10.1136/bmj.c221openalex-snapshot
Meta-analysis of individual participant data: rationale, conduct, and reporting
inferredcites →https://doi.org/10.1159/000351742openalex-snapshot
The Positive Association of Obesity Variants with Adulthood Adiposity Strengthens over an 80-Year Period: A Gene-by-Birth Year Interaction
inferredcites →https://doi.org/10.1161/circgenetics.109.882696openalex-snapshot
Candidate Gene Association Resource (CARe)
inferredcites →https://doi.org/10.1164/rccm.200611-1723ocopenalex-snapshot
The SERPINE2 Gene is Associated with Chronic Obstructive Pulmonary Disease in Two Large Populations
inferredcites →https://doi.org/10.1177/1741826711409327openalex-snapshot
Glucose levels are associated with cardiovascular disease and death in an international cohort of normal glycaemic and dysglycaemic men and women: the EpiDREAM cohort study
inferredcites →https://doi.org/10.1186/1471-2105-15-10openalex-snapshot
Efficient haplotype block recognition of very long and dense genetic sequences
inferredcites →https://doi.org/10.1186/1471-2105-8-428openalex-snapshot
Cubic exact solutions for the estimation of pairwise haplotype frequencies: implications for linkage disequilibrium analyses and a web tool 'CubeX'
inferredcites →https://doi.org/10.1186/1471-2288-2-8openalex-snapshot
Do multiple outcome measures require p-value adjustment?
inferredcites →https://doi.org/10.1186/s13040-015-0074-0openalex-snapshot
Identifying gene-gene interactions that are highly associated with Body Mass Index using Quantitative Multifactor Dimensionality Reduction (QMDR)
inferredcites →https://doi.org/10.1186/s13742-015-0047-8openalex-snapshot
Second-generation PLINK: rising to the challenge of larger and richer datasets
inferredcites →https://doi.org/10.1198/016214502388618591openalex-snapshot
Markov Chain Marginal Bootstrap
inferredcites →https://doi.org/10.1198/106186005x27563openalex-snapshot
Practical Confidence Intervals for Regression Quantiles
inferredcites →https://doi.org/10.1210/en.2015-1068openalex-snapshot
Revisiting PC1/3 Mutants: Dominant-Negative Effect of Endoplasmic Reticulum-Retained Mutants
inferredcites →https://doi.org/10.1210/jc.2008-1595openalex-snapshot
Obesity and the Metabolic Syndrome in Developing Countries
inferredcites →https://doi.org/10.1371/journal.pgen.1000421openalex-snapshot
A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci
inferredcites →https://doi.org/10.1371/journal.pgen.1000981openalex-snapshot
On the Use of Variance per Genotype as a Tool to Identify Quantitative Trait Interaction Effects: A Report from the Women's Genome Health Study
inferredcites →https://doi.org/10.1371/journal.pgen.1003348openalex-snapshot
Power and Predictive Accuracy of Polygenic Risk Scores
inferredcites →https://doi.org/10.1371/journal.pgen.1003607openalex-snapshot
Gene × Physical Activity Interactions in Obesity: Combined Analysis of 111,421 Individuals of European Ancestry
inferredcites →https://doi.org/10.1371/journal.pgen.1004517openalex-snapshot
Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes
inferredcites →https://doi.org/10.1371/journal.pmed.1001116openalex-snapshot
Physical Activity Attenuates the Influence of FTO Variants on Obesity Risk: A Meta-Analysis of 218,166 Adults and 19,268 Children
inferredcites →https://doi.org/10.1371/journal.pone.0003583openalex-snapshot
Concept, Design and Implementation of a Cardiovascular Gene-Centric 50 K SNP Array for Large-Scale Genomic Association Studies
inferredcites →https://doi.org/10.1371/journal.pone.0019057openalex-snapshot
Genetic Markers of Obesity Risk: Stronger Associations with Body Composition in Overweight Compared to Normal-Weight Children
inferredcites →https://doi.org/10.1371/journal.pone.0020816openalex-snapshot
Increased Genetic Variance of BMI with a Higher Prevalence of Obesity
inferredcites →https://doi.org/10.1371/journal.pone.0027135openalex-snapshot
Increasing Genetic Variance of Body Mass Index during the Swedish Obesity Epidemic
inferredcites →https://doi.org/10.1371/journal.pone.0028764openalex-snapshot
Quantile-Specific Penetrance of Genes Affecting Lipoproteins, Adiposity and Height
inferredcites →https://doi.org/10.1371/journal.pone.0056976openalex-snapshot
Linear Regression in Genetic Association Studies
inferredcites →https://doi.org/10.1375/136905203770326402openalex-snapshot
Heritability of Adult Body Height: A Comparative Study of Twin Cohorts in Eight Countries
inferredcites →https://doi.org/10.1515/sagmb-2012-0039openalex-snapshot
The mid p-value in exact tests for Hardy-Weinberg equilibrium
inferredcites →https://doi.org/10.18637/jss.v036.i03openalex-snapshot
Conducting Meta-Analyses in R with the metafor Package
inferredcites →https://doi.org/10.18637/jss.v036.i11openalex-snapshot
Feature Selection with the Boruta Package
inferredcites →https://doi.org/10.2307/1912528openalex-snapshot
Robust Tests for Heteroscedasticity Based on Regression Quantiles
inferredcites →https://doi.org/10.2337/db07-0910openalex-snapshot
Low Physical Activity Accentuates the Effect of the FTO rs9939609 Polymorphism on Body Fat Accumulation
inferredcites →https://doi.org/10.2337/db11-0415openalex-snapshot
Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes
inferredcites →https://doi.org/10.2337/db14-0563openalex-snapshot
Genome-Wide Association Meta-analysis Identifies Novel Variants Associated With Fasting Plasma Glucose in East Asians
inferredcites →https://doi.org/10.2337/dc10-0948openalex-snapshot
Lifestyle Interaction With Fat Mass and Obesity-Associated (FTO) Genotype and Risk of Obesity in Apparently Healthy U.S. Women
inferredcites →https://doi.org/10.2337/dc10-s062openalex-snapshot
Diagnosis and Classification of Diabetes Mellitus
inferredcites →https://doi.org/10.2337/dc11-s062openalex-snapshot
Diagnosis and Classification of Diabetes Mellitus
inferredcites →https://doi.org/10.2337/diabetes.52.12.2984openalex-snapshot
Autosomal-Dominant Mode of Inheritance of a Melanocortin-4 Receptor Mutation in a Patient with Severe Early-Onset Obesity Is Due to a Dominant-Negative Effect Caused by Receptor Dimerization
inferredcites →https://doi.org/10.32614/r.manualsopenalex-snapshot
R: A Language and Environment for Statistical Computing
inferredcites →https://doi.org/10.3389/fgene.2014.00370openalex-snapshot
Imputation and quality control steps for combining multiple genome-wide datasets
inferredcites →https://doi.org/10.3945/ajcn.112.038125openalex-snapshot
TCF7L2 genetic variants modulate the effect of dietary fat intake on changes in body composition during a weight-loss intervention
inferredcites →https://doi.org/10.3945/jn.111.143826openalex-snapshot
A High Intake of Saturated Fatty Acids Strengthens the Association between the Fat Mass and Obesity-Associated Gene and BMI
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1002/osp4.293openalex-snapshot
Provider bias as a function of patient genotype: polygenic score analysis among diabetics from the Health and Retirement Study
inferred← citeshttps://doi.org/10.1016/j.ajhg.2017.10.007openalex-snapshot
Penetrance of Polygenic Obesity Susceptibility Loci across the Body Mass Index Distribution
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