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Assessing the Gene Regulatory Landscape in 1,188 Human Tumors
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Statistical Testing of Shared Genetic Control for Potentially Related Traits
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Smoking and cancer‐related gene expression in bronchial epithelium and non‐small‐cell lung cancers
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Inference of Allele-Specific Expression from RNA-seq Data
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Somatic alterations in the human cancer genome
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Lessons from the Cancer Genome
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Cancer/testis antigens: an expanding family of targets for cancer immunotherapy
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The moderator-mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations.
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Gene Ontology: tool for the unification of biology
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Immune targets and neoantigens for cancer immunotherapy and precision medicine
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Melanocytes as Instigators and Victims of Oxidative Stress
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Highly recurrent mutations of SGK1, DUSP2 and JUNB in nodular lymphocyte predominant Hodgkin lymphoma
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A comprehensive catalogue of somatic mutations from a human cancer genome
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Integrated genomic characterization of endometrial carcinoma
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Signatures of mutational processes in human cancer
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Putative cis-regulatory drivers in colorectal cancer
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Integrative analysis of 111 reference human epigenomes
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Common genetic variation drives molecular heterogeneity in human iPSCs
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Genetic effects on gene expression across human tissues
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Integrated analysis of germline and somatic variants in ovarian cancer
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Systematic analysis of somatic mutations impacting gene expression in 12 tumour types
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The Cancer Genome Atlas Pan-Cancer analysis project
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A general framework for estimating the relative pathogenicity of human genetic variants
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Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer
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Genome-wide analysis of noncoding regulatory mutations in cancer
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Systematic analysis of noncoding somatic mutations and gene expression alterations across 14 tumor types
inferredcites →https://doi.org/10.1038/ng.3664openalex-snapshot
The rules and impact of nonsense-mediated mRNA decay in human cancers
inferredcites →https://doi.org/10.1038/ng.3670openalex-snapshot
Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBEC-signature mutations in tumors
inferredcites →https://doi.org/10.1038/nprot.2009.86openalex-snapshot
Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm
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Cancer/testis antigens, gametogenesis and cancer
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p21 in cancer: intricate networks and multiple activities
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The ID proteins: master regulators of cancer stem cells and tumour aggressiveness
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Framework for quality assessment of whole genome cancer sequences
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Pan-cancer analysis of whole genomes
inferredcites →https://doi.org/10.1038/sj.onc.1203426openalex-snapshot
Prostate stem cell antigen (PSCA) expression increases with high gleason score, advanced stage and bone metastasis in prostate cancer
inferredcites →https://doi.org/10.1038/srep37393openalex-snapshot
Changes of bivalent chromatin coincide with increased expression of developmental genes in cancer
inferredcites →https://doi.org/10.1038/srep44997openalex-snapshot
Gene expression-based biomarkers for discriminating early and late stage of clear cell renal cancer
inferredcites →https://doi.org/10.1046/j.1365-2133.2001.03952.xopenalex-snapshot
Increased sensitivity of melanocytes to oxidative stress and abnormal expression of tyrosinase-related protein in vitiligo
inferredcites →https://doi.org/10.1046/j.1523-1747.1999.00653.xopenalex-snapshot
The Role of Melanin in the Induction of Oxidative DNA Base Damage by Ultraviolet A Irradiation of DNA or Melanoma Cells
inferredcites →https://doi.org/10.1053/j.gastro.2013.07.040openalex-snapshot
A Gene Expression Signature of Epithelial Tubulogenesis and a Role for ASPM in Pancreatic Tumor Progression
inferredcites →https://doi.org/10.1073/pnas.0506580102openalex-snapshot
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
inferredcites →https://doi.org/10.1073/pnas.1308512110openalex-snapshot
Mammalian Exo1 encodes both structural and catalytic functions that play distinct roles in essential biological processes
inferredcites →https://doi.org/10.1080/23723556.2015.1033588openalex-snapshot
Unanticipated role of melanin in causing carcinogenic cyclobutane pyrimidine dimers
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International Cancer Genome Consortium Data Portal--a one-stop shop for cancer genomics data
inferredcites →https://doi.org/10.1093/nar/gku1179openalex-snapshot
Gene Ontology Consortium: going forward
inferredcites →https://doi.org/10.1093/nar/gkv101openalex-snapshot
Ovarian carcinoma CDK12 mutations misregulate expression of DNA repair genes via deficient formation and function of the Cdk12/CycK complex
inferredcites →https://doi.org/10.1093/nar/gkv1351openalex-snapshot
The Reactome pathway Knowledgebase
inferredcites →https://doi.org/10.1093/nar/gkv419openalex-snapshot
Signatures of accelerated somatic evolution in gene promoters in multiple cancer types
inferredcites →https://doi.org/10.1093/nar/gkw1121openalex-snapshot
COSMIC: somatic cancer genetics at high-resolution
inferredcites →https://doi.org/10.1093/nar/gkx247openalex-snapshot
GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses
inferredcites →https://doi.org/10.1101/161562openalex-snapshot
The evolutionary history of 2,658 cancers
inferredcites →https://doi.org/10.1101/161638openalex-snapshot
Large-Scale Uniform Analysis of Cancer Whole Genomes in Multiple Computing Environments
inferredcites →https://doi.org/10.1101/183889openalex-snapshot
Genomic basis for RNA alterations revealed by whole-genome analyses of 27 cancer types
inferredcites →https://doi.org/10.1101/cshperspect.a001008openalex-snapshot
TP53 Mutations in Human Cancers: Origins, Consequences, and Clinical Use
inferredcites →https://doi.org/10.1101/gr.135350.111openalex-snapshot
GENCODE: The reference human genome annotation for The ENCODE Project
inferredcites →https://doi.org/10.1101/gr.137570.112openalex-snapshot
Integrative analysis of genome-wide loss of heterozygosity and monoallelic expression at nucleotide resolution reveals disrupted pathways in triple-negative breast cancer
inferredcites →https://doi.org/10.1111/bjh.13995openalex-snapshot
A high rate of telomeric sister chromatid exchange occurs in chronic lymphocytic leukaemia B‐cells
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Oncogenic role of kinesin proteins and targeting kinesin therapy
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Genome-wide Profiling of Genetic Synthetic Lethality Identifies CDK12 as a Novel Determinant of PARP1/2 Inhibitor Sensitivity
inferredcites →https://doi.org/10.1158/1538-7445.am2018-218openalex-snapshot
Abstract 218: The evolutionary history of 2,658 cancers
inferredcites →https://doi.org/10.1172/jci81522openalex-snapshot
Involvement of activation-induced cytidine deaminase in skin cancer development
inferredcites →https://doi.org/10.1182/blood-2011-04-350579openalex-snapshot
IRF4 mutations in chronic lymphocytic leukemia
inferredcites →https://doi.org/10.1186/1471-2407-12-520openalex-snapshot
Serological identification of Tektin5 as a cancer/testis antigen and its immunogenicity
inferredcites →https://doi.org/10.1186/1471-2407-14-7openalex-snapshot
Overexpression of phosphatidylinositol 4-kinase type IIIα is associated with undifferentiated status and poor prognosis of human hepatocellular carcinoma
inferredcites →https://doi.org/10.1186/1755-8794-7-11openalex-snapshot
Patterns and processes of somatic mutations in nine major cancers
inferredcites →https://doi.org/10.1186/2162-3619-2-26openalex-snapshot
ABC transporter activity linked to radiation resistance and molecular subtype in pediatric medulloblastoma
inferredcites →https://doi.org/10.1186/s13059-015-0762-6openalex-snapshot
Tools and best practices for data processing in allelic expression analysis
inferredcites →https://doi.org/10.1242/dev.113027openalex-snapshot
Poised chromatin in the mammalian germ line
inferredcites →https://doi.org/10.1371/journal.pgen.1002888openalex-snapshot
SLX-1 Is Required for Maintaining Genomic Integrity and Promoting Meiotic Noncrossovers in the Caenorhabditis elegans Germline
inferredcites →https://doi.org/10.1371/journal.pgen.1004461openalex-snapshot
Cis and Trans Effects of Human Genomic Variants on Gene Expression
inferredcites →https://doi.org/10.1371/journal.pgen.1006385openalex-snapshot
The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts
inferredcites →https://doi.org/10.1593/neo.12942openalex-snapshot
Tight Junction Proteins Claudin-3 and Claudin-4 Control Tumor Growth and Metastases
inferredcites →https://doi.org/10.3390/cancers4041180openalex-snapshot
Annotating Cancer Variants and Anti-Cancer Therapeutics in Reactome
inferredcites →https://doi.org/10.3758/bf03206553openalex-snapshot
SPSS and SAS procedures for estimating indirect effects in simple mediation models
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1093/nar/gkab031openalex-snapshot
DeCompress: tissue compartment deconvolution of targeted mRNA expression panels using compressed sensing
inferred← citeshttps://doi.org/10.1101/631150openalex-snapshot
Allelic imbalance reveals widespread germline-somatic regulatory differences and prioritizes risk loci in Renal Cell Carcinoma
inferred← citeshttps://doi.org/10.1186/s13059-020-1942-6openalex-snapshot
A framework for transcriptome-wide association studies in breast cancer in diverse study populations
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