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Widespread and targeted gene expression by systemic AAV vectors: Production, purification, and administration
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/0471142301.ns0417s57openalex-snapshot
Production of Recombinant Adeno‐Associated Viral Vectors and Use in In Vitro and In Vivo Administration
inferredcites →https://doi.org/10.1002/biot.201400046openalex-snapshot
CRISPR/Cas9‐mediated genome engineering: An adeno‐associated viral (AAV) vector toolbox
inferredcites →https://doi.org/10.1002/j.1460-2075.1991.tb04979.xopenalex-snapshot
A CAAX or a CAAL motif and a second signal are sufficient for plasma membrane targeting of ras proteins.
inferredcites →https://doi.org/10.1016/j.cell.2014.07.017openalex-snapshot
Single-Cell Phenotyping within Transparent Intact Tissue through Whole-Body Clearing
inferredcites →https://doi.org/10.1016/j.cell.2015.03.022openalex-snapshot
Vagal Sensory Neuron Subtypes that Differentially Control Breathing
inferredcites →https://doi.org/10.1016/j.cell.2015.06.067openalex-snapshot
Clarifying Tissue Clearing
inferredcites →https://doi.org/10.1016/j.cell.2015.07.014openalex-snapshot
Intact-Brain Analyses Reveal Distinct Information Carried by SNc Dopamine Subcircuits
inferredcites →https://doi.org/10.1016/j.cell.2016.05.011openalex-snapshot
Sensory Neurons that Detect Stretch and Nutrients in the Digestive System
inferredcites →https://doi.org/10.1016/j.jviromet.2006.07.024openalex-snapshot
Transfection of mammalian cells using linear polyethylenimine is a simple and effective means of producing recombinant adeno-associated virus vectors
inferredcites →https://doi.org/10.1016/j.neuron.2016.09.021openalex-snapshot
A Designer AAV Variant Permits Efficient Retrograde Access to Projection Neurons
inferredcites →https://doi.org/10.1016/j.neuron.2017.04.017openalex-snapshot
Global Representations of Goal-Directed Behavior in Distinct Cell Types of Mouse Neocortex
inferredcites →https://doi.org/10.1016/j.ymthe.2017.08.004openalex-snapshot
AAV-PHP.B-Mediated Global-Scale Expression in the Mouse Nervous System Enables GBA1 Gene Therapy for Wide Protection from Synucleinopathy
inferredcites →https://doi.org/10.1038/gt.2009.148openalex-snapshot
Progress and prospects: immune responses to viral vectors
inferredcites →https://doi.org/10.1038/gt.2009.157openalex-snapshot
High AAV vector purity results in serotype- and tissue-independent enhancement of transduction efficiency
inferredcites →https://doi.org/10.1038/gt.2011.207openalex-snapshot
AAV-based shRNA silencing of NF-κB ameliorates muscle pathologies in mdx mice
inferredcites →https://doi.org/10.1038/laban0511-155openalex-snapshot
Retro-orbital injections in mice
inferredcites →https://doi.org/10.1038/mt.2010.279openalex-snapshot
MicroRNA-regulated, Systemically Delivered rAAV9: A Step Closer to CNS-restricted Transgene Expression
inferredcites →https://doi.org/10.1038/mt.2011.72openalex-snapshot
Preclinical Differences of Intravascular AAV9 Delivery to Neurons and Glia: A Comparative Study of Adult Mice and Nonhuman Primates
inferredcites →https://doi.org/10.1038/mt.2013.95openalex-snapshot
Mouse Gender Influences Brain Transduction by Intravascularly Administered AAV9
inferredcites →https://doi.org/10.1038/mtm.2013.9openalex-snapshot
Empty virions in AAV8 vector preparations reduce transduction efficiency and may cause total viral particle dose-limiting side effects
inferredcites →https://doi.org/10.1038/nature14299openalex-snapshot
In vivo genome editing using Staphylococcus aureus Cas9
inferredcites →https://doi.org/10.1038/nbt.3440openalex-snapshot
Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain
inferredcites →https://doi.org/10.1038/nbt.3469openalex-snapshot
A dual AAV system enables the Cas9-mediated correction of a metabolic liver disease in newborn mice
inferredcites →https://doi.org/10.1038/nm.2025openalex-snapshot
Molecular signatures of disease brain endothelia provide new sites for CNS-directed enzyme therapy
inferredcites →https://doi.org/10.1038/nmeth.1512openalex-snapshot
Optogenetic control of heart muscle in vitro and in vivo
inferredcites →https://doi.org/10.1038/nmeth.1784openalex-snapshot
mGRASP enables mapping mammalian synaptic connectivity with light microscopy
inferredcites →https://doi.org/10.1038/nmeth.2450openalex-snapshot
Improved tools for the Brainbow toolbox
inferredcites →https://doi.org/10.1038/nn.4107openalex-snapshot
ScaleS: an optical clearing palette for biological imaging
inferredcites →https://doi.org/10.1038/nn.4566openalex-snapshot
Causal evidence for retina-dependent and -independent visual motion computations in mouse cortex
inferredcites →https://doi.org/10.1038/nn.4593openalex-snapshot
Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems
inferredcites →https://doi.org/10.1038/nprot.2006.207openalex-snapshot
Production and characterization of adeno-associated viral vectors
inferredcites →https://doi.org/10.1038/nprot.2007.319openalex-snapshot
Changing medium and passaging cell lines
inferredcites →https://doi.org/10.1038/nprot.2015.122openalex-snapshot
Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping
inferredcites →https://doi.org/10.1038/nprot.2016.021openalex-snapshot
Visualization of cortical, subcortical and deep brain neural circuit dynamics during naturalistic mammalian behavior with head-mounted microscopes and chronically implanted lenses
inferredcites →https://doi.org/10.1038/sj.gt.3300938openalex-snapshot
Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield
inferredcites →https://doi.org/10.1038/sj.gt.3301221openalex-snapshot
Influence of promoter and WHV post-transcriptional regulatory element on AAV-mediated transgene expression in the rat brain
inferredcites →https://doi.org/10.1038/sj.gt.3301529openalex-snapshot
Quantitative comparison of expression with adeno-associated virus (AAV-2) brain-specific gene cassettes
inferredcites →https://doi.org/10.1039/b901966aopenalex-snapshot
The fluorescent protein palette: tools for cellular imaging
inferredcites →https://doi.org/10.1073/pnas.0906593106openalex-snapshot
A chemical-genetic approach to study G protein regulation of β cell function in vivo
inferredcites →https://doi.org/10.1089/hgtb.2015.051openalex-snapshot
Comparative Analysis of Cesium Chloride- and Iodixanol-Based Purification of Recombinant Adeno-Associated Viral Vectors for Preclinical Applications
inferredcites →https://doi.org/10.1089/hgtb.2015.140openalex-snapshot
Expressing Transgenes That Exceed the Packaging Capacity of Adeno-Associated Virus Capsids
inferredcites →https://doi.org/10.1089/hum.2009.064openalex-snapshot
Transient Transfection Methods for Clinical Adeno-Associated Viral Vector Production
inferredcites →https://doi.org/10.1089/hum.2010.055openalex-snapshot
Rapid, Simple, and Versatile Manufacturing of Recombinant Adeno-Associated Viral Vectors at Scale
inferredcites →https://doi.org/10.1089/hum.2010.245openalex-snapshot
Optimizing Promoters for Recombinant Adeno-Associated Virus-Mediated Gene Expression in the Peripheral and Central Nervous System Using Self-Complementary Vectors
inferredcites →https://doi.org/10.1126/sageke.2005.5.re1openalex-snapshot
Lipofuscin and Aging: A Matter of Toxic Waste
inferredcites →https://doi.org/10.1128/jvi.72.3.2224-2232.1998openalex-snapshot
Production of High-Titer Recombinant Adeno-Associated Virus Vectors in the Absence of Helper Adenovirus
inferredcites →https://doi.org/10.1146/annurev-virology-031413-085355openalex-snapshot
AAV-Mediated Gene Therapy for Research and Therapeutic Purposes
inferredcites →https://doi.org/10.1172/jci66432openalex-snapshot
Chronic activation of a designer Gq-coupled receptor improves β cell function
inferredcites →https://doi.org/10.1182/blood-2013-01-306647openalex-snapshot
Immune responses to AAV vectors: overcoming barriers to successful gene therapy
inferredcites →https://doi.org/10.1186/1756-6606-7-17openalex-snapshot
Optimization of AAV expression cassettes to improve packaging capacity and transgene expression in neurons
inferredcites →https://doi.org/10.1186/s13041-016-0232-4openalex-snapshot
rAAV-compatible MiniPromoters for restricted expression in the brain and eye
inferredcites →https://doi.org/10.1210/en.2012-2127openalex-snapshot
A Novel Experimental Strategy to Assess the Metabolic Effects of Selective Activation of a Gq-Coupled Receptor in Hepatocytes In Vivo
inferredcites →https://doi.org/10.1371/journal.pone.0067680openalex-snapshot
Capsid Serotype and Timing of Injection Determines AAV Transduction in the Neonatal Mice Brain
inferredcites →https://doi.org/10.17615/2x9m-k248openalex-snapshot
Viral Expression Cassette Elements to Enhance Transgene Target Specificity and Expression in Gene Therapy
inferredcites →https://doi.org/10.2144/000114170openalex-snapshot
Comparative Next-Generation Sequencing of Adeno-Associated Virus Inverted Terminal Repeats
inferredcites →https://doi.org/10.3389/fnmol.2016.00116openalex-snapshot
Better Targeting, Better Efficiency for Wide-Scale Neuronal Transduction with the Synapsin Promoter and AAV-PHP.B
inferredcites →https://doi.org/10.3389/fnmol.2016.00154openalex-snapshot
Corrigendum: Better Targeting, Better Efficiency for Wide-Scale Neuronal Transduction with the Synapsin Promoter and AAV-PHP.B
inferredcites →https://doi.org/10.7554/elife.12727openalex-snapshot
Sensitive red protein calcium indicators for imaging neural activity
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1007/978-1-0716-0830-2_16openalex-snapshot
Application of Targeting-Optimized Chronos for Stimulation of the Auditory Pathway
inferred← citeshttps://doi.org/10.1016/j.cell.2021.08.028openalex-snapshot
Directed evolution of a family of AAV capsid variants enabling potent muscle-directed gene delivery across species
inferred← citeshttps://doi.org/10.1016/j.celrep.2023.113465openalex-snapshot
MCUb is an inducible regulator of calcium-dependent mitochondrial metabolism and substrate utilization in muscle
inferred← citeshttps://doi.org/10.1016/j.expneurol.2024.114810openalex-snapshot
Retrograde AAV-mediated gene modulation reveals chloride intracellular channel proteins as potent regulators of retinal ganglion cell death
inferred← citeshttps://doi.org/10.1038/d41586-018-07197-0openalex-snapshot
Tapping into the brain’s star power
inferred← citeshttps://doi.org/10.1038/s41467-019-09770-1openalex-snapshot
Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies
inferred← citeshttps://doi.org/10.1038/s41467-024-55470-wopenalex-snapshot
Synaptic signatures and disease vulnerabilities of layer 5 pyramidal neurons
inferred← citeshttps://doi.org/10.1038/s41586-019-1484-9openalex-snapshot
Niche stiffness underlies the ageing of central nervous system progenitor cells
inferred← citeshttps://doi.org/10.1101/2023.07.26.550187openalex-snapshot
Ribosomal Protein SA (RPSA) is required for localized translation and sarcomere maintenance in mice
inferred← citeshttps://doi.org/10.1101/2024.08.02.605568openalex-snapshot
Refining gene delivery to skeletal muscle with a dual-strategy approach of muscle-tropic AAV capsids and muscle-specific promoters
inferred← citeshttps://doi.org/10.1101/2024.09.09.612044openalex-snapshot
Virally encoded single-chain antibody fragments targeting alpha-synuclein protect against motor impairments and neuropathology in a mouse model of synucleinopathy
inferred← citeshttps://doi.org/10.1126/science.abg6155openalex-snapshot
Mammalian retrovirus-like protein PEG10 packages its own mRNA and can be pseudotyped for mRNA delivery
inferred← citeshttps://doi.org/10.1126/science.adk2539openalex-snapshot
Creation of de novo cryptic splicing for ALS and FTD precision medicine
inferred← citeshttps://doi.org/10.1172/jci174527openalex-snapshot
Localized translation and sarcomere maintenance requires ribosomal protein SA in mice
inferred← citeshttps://doi.org/10.1186/s11658-023-00472-7openalex-snapshot
Genetically encoded phosphatidylserine biosensor for in vitro, ex vivo and in vivo labelling
inferred← citeshttps://doi.org/10.1523/jneurosci.1677-18.2018openalex-snapshot
Whole-Brain Analysis of Cells and Circuits by Tissue Clearing and Light-Sheet Microscopy
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