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Genome-wide gene-environment analyses of depression and reported lifetime traumatic experiences in UK Biobank

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Childhood Adversities and Adult Psychiatric Disorders in the National Comorbidity Survey Replication I

inferredcites →https://doi.org/10.1001/archgenpsychiatry.2010.2openalex-snapshot

Overweight, Obesity, and Depression

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The Validity of Four Definitions of Endogenous Depression

inferredcites →https://doi.org/10.1002/0471250953.bi1112s47openalex-snapshot

BEDTools: The Swiss‐Army Tool for Genome Feature Analysis

inferredcites →https://doi.org/10.1002/ajmg.1320480107openalex-snapshot

Do genes influence exposure to trauma? A twin study of combat

inferredcites →https://doi.org/10.1002/da.20704openalex-snapshot

Depression and obesity: do shared genes explain the relationship?

inferredcites →https://doi.org/10.1002/da.22484openalex-snapshot

GENOME-WIDE ASSOCIATION STUDY (GWAS) AND GENOME-WIDE BY ENVIRONMENT INTERACTION STUDY (GWEIS) OF DEPRESSIVE SYMPTOMS IN AFRICAN AMERICAN AND HISPANIC/LATINA WOMEN

inferredcites →https://doi.org/10.1002/gepi.20297openalex-snapshot

Estimation of significance thresholds for genomewide association scans

inferredcites →https://doi.org/10.1016/j.ajhg.2017.03.004openalex-snapshot

Human Demographic History Impacts Genetic Risk Prediction across Diverse Populations

inferredcites →https://doi.org/10.1016/j.biopsych.2013.09.006openalex-snapshot

Gene × Environment Interaction Studies Have Not Properly Controlled for Potential Confounders: The Problem and the (Simple) Solution

inferredcites →https://doi.org/10.1016/j.biopsych.2017.09.009openalex-snapshot

Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium

inferredcites →https://doi.org/10.1016/j.chiabu.2003.09.008openalex-snapshot

Prevalence and psychological sequelae of self-reported childhood physical and sexual abuse in a general population sample of men and women

inferredcites →https://doi.org/10.1016/j.chiabu.2007.02.004openalex-snapshot

Resilience to adult psychopathology following childhood maltreatment: Evidence from a community sample

inferredcites →https://doi.org/10.1016/j.cub.2016.09.035openalex-snapshot

Molecular Genetic Contributions to Social Deprivation and Household Income in UK Biobank

inferredcites →https://doi.org/10.1016/j.jesp.2003.10.001openalex-snapshot

Adjusting researchers’ approach to adjustment: On the use of covariates when testing interactions

inferredcites →https://doi.org/10.1016/j.psychres.2009.04.015openalex-snapshot

Depression and obesity: A meta-analysis of community-based studies

inferredcites →https://doi.org/10.1017/s0033291709992121openalex-snapshot

Childhood adversity, adult stressful life events, and risk of past-year psychiatric disorder: a test of the stress sensitization hypothesis in a population-based sample of adults

inferredcites →https://doi.org/10.1017/s0033291712002589openalex-snapshot

Estimating the heritability of reporting stressful life events captured by common genetic variants

inferredcites →https://doi.org/10.1017/s0033291715002172openalex-snapshot

Polygenic interactions with environmental adversity in the aetiology of major depressive disorder

inferredcites →https://doi.org/10.1017/s0033291797004716openalex-snapshot

Stressful life events and genetic liability to major depression: genetic control of exposure to the environment?

inferredcites →https://doi.org/10.1017/s0033291797005588openalex-snapshot

Childhood adversity and adult psychiatric disorder in the US National Comorbidity Survey

inferredcites →https://doi.org/10.1037/h0041029openalex-snapshot

Schizotaxia, schizotypy, schizophrenia.

inferredcites →https://doi.org/10.1038/mp.2016.49openalex-snapshot

Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci

inferredcites →https://doi.org/10.1038/nature13595openalex-snapshot

Biological insights from 108 schizophrenia-associated genetic loci

inferredcites →https://doi.org/10.1038/nature14177openalex-snapshot

Genetic studies of body mass index yield new insights for obesity biology

inferredcites →https://doi.org/10.1038/nature14962openalex-snapshot

The UK10K project identifies rare variants in health and disease

inferredcites →https://doi.org/10.1038/nature15394openalex-snapshot

An integrated map of structural variation in 2,504 human genomes

inferredcites →https://doi.org/10.1038/nature19057openalex-snapshot

Analysis of protein-coding genetic variation in 60,706 humans

inferredcites →https://doi.org/10.1038/ng.3211openalex-snapshot

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

inferredcites →https://doi.org/10.1038/ng.3285openalex-snapshot

Meta-analysis of the heritability of human traits based on fifty years of twin studies

inferredcites →https://doi.org/10.1038/ng.3406openalex-snapshot

An atlas of genetic correlations across human diseases and traits

inferredcites →https://doi.org/10.1038/ng.3552openalex-snapshot

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

inferredcites →https://doi.org/10.1038/ng.3623openalex-snapshot

Identification of 15 genetic loci associated with risk of major depression in individuals of European descent

inferredcites →https://doi.org/10.1038/ng.3643openalex-snapshot

A reference panel of 64,976 haplotypes for genotype imputation

inferredcites →https://doi.org/10.1038/ng.3768openalex-snapshot

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

inferredcites →https://doi.org/10.1038/ng.3941openalex-snapshot

Concepts, estimation and interpretation of SNP-based heritability

inferredcites →https://doi.org/10.1038/ng.3949openalex-snapshot

Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis

inferredcites →https://doi.org/10.1038/ng.943openalex-snapshot

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

inferredcites →https://doi.org/10.1038/s41398-018-0150-6openalex-snapshot

GWAS on family history of Alzheimer’s disease

inferredcites →https://doi.org/10.1038/s41588-017-0013-8openalex-snapshot

Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism

inferredcites →https://doi.org/10.1038/s41588-018-0090-3openalex-snapshot

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

inferredcites →https://doi.org/10.1038/s41588-018-0144-6openalex-snapshot

Mixed-model association for biobank-scale datasets

inferredcites →https://doi.org/10.1038/s41588-018-0151-7openalex-snapshot

Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways

inferredcites →https://doi.org/10.1038/s41588-019-0469-9openalex-snapshot

Author Correction: Multi-trait analysis of genome-wide association summary statistics using MTAG

inferredcites →https://doi.org/10.1046/j.1360-0443.2001.969130710.xopenalex-snapshot

Intra‐ and extra‐familial influences on alcohol and drug misuse: a twin study of gene–environment correlation

inferredcites →https://doi.org/10.1093/bioinformatics/btq559openalex-snapshot

Robust relationship inference in genome-wide association studies

inferredcites →https://doi.org/10.1093/bioinformatics/btu848openalex-snapshot

PRSice: Polygenic Risk Score software

inferredcites →https://doi.org/10.1093/bioinformatics/btw613openalex-snapshot

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

inferredcites →https://doi.org/10.1093/bioinformatics/btx299openalex-snapshot

FlashPCA2: principal component analysis of Biobank-scale genotype datasets

inferredcites →https://doi.org/10.1093/schbul/sbl053openalex-snapshot

Environment and Schizophrenia: Environmental Factors in Schizophrenia: Childhood Trauma--A Critical Review

inferredcites →https://doi.org/10.1097/hrp.0000000000000054openalex-snapshot

Genetic Determinants of Depression

inferredcites →https://doi.org/10.1101/166298openalex-snapshot

Genome-wide genetic data on ~500,000 UK Biobank participants

inferredcites →https://doi.org/10.1111/1467-9884.00122openalex-snapshot

Comparing measures of sample skewness and kurtosis

inferredcites →https://doi.org/10.1111/j.2047-6310.2013.00196.xopenalex-snapshot

The association between childhood sexual and physical abuse with incident adult severe obesity across 13 years of the N ational L ongitudinal S tudy of A dolescent H ealth

inferredcites →https://doi.org/10.1111/jcpp.12621openalex-snapshot

Lest we forget: comparing retrospective and prospective assessments of adverse childhood experiences in the prediction of adult health

inferredcites →https://doi.org/10.1126/scitranslmed.3008601openalex-snapshot

UK Biobank Data: Come and Get It

inferredcites →https://doi.org/10.1136/bmj.i582openalex-snapshot

Height, body mass index, and socioeconomic status: mendelian randomisation study in UK Biobank

inferredcites →https://doi.org/10.1136/jech-2016-208064.41openalex-snapshot

OP41 The representativeness of the UK Biobank cohort on a range of sociodemographic, physical, lifestyle and health-related characteristics

inferredcites →https://doi.org/10.1146/annurev.psych.48.1.191openalex-snapshot

THE EFFECTS OF STRESSFUL LIFE EVENTS ON DEPRESSION

inferredcites →https://doi.org/10.1176/ajp.151.8.1132openalex-snapshot

Initial reliability and validity of a new retrospective measure of child abuse and neglect

inferredcites →https://doi.org/10.1176/ajp.156.6.837openalex-snapshot

Causal Relationship Between Stressful Life Events and the Onset of Major Depression

inferredcites →https://doi.org/10.1176/appi.ajp.159.10.1675openalex-snapshot

Genetic and Environmental Influences on Trauma Exposure and Posttraumatic Stress Disorder Symptoms: A Twin Study

inferredcites →https://doi.org/10.1176/appi.ajp.2011.11020335openalex-snapshot

Childhood Maltreatment Predicts Unfavorable Course of Illness and Treatment Outcome in Depression: A Meta-Analysis

inferredcites →https://doi.org/10.1176/appi.ajp.2017.17060621openalex-snapshot

Molecular Genetic Analysis Subdivided by Adversity Exposure Suggests Etiologic Heterogeneity in Major Depression

inferredcites →https://doi.org/10.1177/1077559511403920openalex-snapshot

A Global Perspective on Child Sexual Abuse: Meta-Analysis of Prevalence Around the World

inferredcites →https://doi.org/10.1186/1741-7015-12-72openalex-snapshot

National household survey of adverse childhood experiences and their relationship with resilience to health-harming behaviors in England

inferredcites →https://doi.org/10.1186/s13742-015-0047-8openalex-snapshot

Second-generation PLINK: rising to the challenge of larger and richer datasets

inferredcites →https://doi.org/10.1192/bjp.154.4.564openalex-snapshot

The Camberwell Collaborative Depression Study

inferredcites →https://doi.org/10.1192/bjp.bp.113.143081openalex-snapshot

Effect of polygenic risk scores on depression in childhood trauma

inferredcites →https://doi.org/10.1371/journal.pone.0075362openalex-snapshot

Prevalence and Characteristics of Probable Major Depression and Bipolar Disorder within UK Biobank: Cross-Sectional Study of 172,751 Participants

inferredcites →https://doi.org/10.1534/genetics.117.300360openalex-snapshot

Transformation of Summary Statistics from Linear Mixed Model Association on All-or-None Traits to Odds Ratio

inferredcites →https://doi.org/10.2105/ajph.91.5.753openalex-snapshot

Child sexual abuse and subsequent psychopathology: results from the National Comorbidity Survey

inferredcites →https://doi.org/10.2307/3090206openalex-snapshot

Stability of Retrospective Reports in Depression: Traumatic Events, Past Depressive Episodes, and Parental Psychopathology

inferredcites →https://doi.org/10.2337/db10-0502openalex-snapshot

Common Variants at 10 Genomic Loci Influence Hemoglobin A1C Levels via Glycemic and Nonglycemic Pathways

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1007/978-3-030-14792-1_15openalex-snapshot

m6A mRNA Methylation in the Mammalian Brain: Distribution, Function and Implications for Brain Functions

inferred← citeshttps://doi.org/10.1016/b978-0-12-813176-3.00016-xopenalex-snapshot

Genomics of major depressive disorder

inferred← citeshttps://doi.org/10.1016/j.biopsych.2019.10.015openalex-snapshot

The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls

inferred← citeshttps://doi.org/10.1017/s0033291721000945openalex-snapshot

Associations and limited shared genetic aetiology between bipolar disorder and cardiometabolic traits in the UK Biobank

inferred← citeshttps://doi.org/10.1038/s41380-019-0457-6openalex-snapshot

Genomics and psychological resilience: a research agenda

inferred← citeshttps://doi.org/10.1038/s41398-018-0356-7openalex-snapshot

A validation of the diathesis-stress model for depression in Generation Scotland

inferred← citeshttps://doi.org/10.1038/s41398-018-0360-yopenalex-snapshot

Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland

inferred← citeshttps://doi.org/10.1038/s41398-020-01009-8openalex-snapshot

The effects of polygenic risk for psychiatric disorders and smoking behaviour on psychotic experiences in UK Biobank

inferred← citeshttps://doi.org/10.1038/s41398-020-0706-0openalex-snapshot

Genomic influences on self-reported childhood maltreatment

inferred← citeshttps://doi.org/10.1038/s42003-021-02469-4openalex-snapshot

Association between polygenic propensity for psychiatric disorders and nutrient intake

inferred← citeshttps://doi.org/10.1101/645077openalex-snapshot

Genetic comorbidity between major depression and cardio-metabolic disease, stratified by age at onset of major depression

inferred← citeshttps://doi.org/10.1176/appi.ajp.2019.18091014openalex-snapshot

Polygenic Risk: Predicting Depression Outcomes in Clinical and Epidemiological Cohorts of Youths

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