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MicroPheno: Predicting environments and host phenotypes from 16S rRNA gene sequencing using a k-mer based representation of shallow sub-samples

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Alterations in the gut microbiome of children with severe ulcerative colitis
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Analysis of 16S rRNA Gene Amplicon Sequences Using the QIIME Software Package
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Host Phenotype Prediction from Differentially Abundant Microbes Using RoDEO
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Manipulating the soil microbiome to increase soil health and plant fertility
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Specificity in Chemical Profiles of Workers, Brood and Mutualistic Fungi in Atta, Acromyrmex, and Sericomyrmex Fungus-growing Ants
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MetaDP: a comprehensive web server for disease prediction of 16S rRNA metagenomic datasets
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The Prevalence and Geographic Distribution of Crohn’s Disease and Ulcerative Colitis in the United States
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Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome
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The Treatment-Naive Microbiome in New-Onset Crohn’s Disease
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Cutaneous Leishmaniasis Induces a Transmissible Dysbiotic Skin Microbiota that Promotes Skin Inflammation
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Targeted sequencing of clade-specific markers from skin microbiomes for forensic human identification
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A detailed analysis of 16S ribosomal RNA gene segments for the diagnosis of pathogenic bacteria
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Bacterial Community Structure in the Drinking Water Microbiome Is Governed by Filtration Processes
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Random Forests
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Fast and sensitive taxonomic classification for metagenomics with Kaiju
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QIIME allows analysis of high-throughput community sequencing data
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Accurate phylogenetic classification of variable-length DNA fragments
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A perspective on 16S rRNA operational taxonomic unit clustering using sequence similarity
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Meta-analysis of gut microbiome studies identifies disease-specific and shared responses
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Dysbiosis in chronic periodontitis: Key microbial players and interactions with the human host
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Gastrointestinal Microbiome Signatures of Pediatric Patients With Irritable Bowel Syndrome
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The Human Intestinal Microbiome in Health and Disease
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Forensic identification using skin bacterial communities
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UCHIME improves sensitivity and speed of chimera detection
inferredcites →https://doi.org/10.1093/bioinformatics/btv683openalex-snapshot
Large-scale machine learning for metagenomics sequence classification
inferredcites →https://doi.org/10.1093/nar/gks1219openalex-snapshot
The SILVA ribosomal RNA gene database project: improved data processing and web-based tools
inferredcites →https://doi.org/10.1093/nar/gkt241openalex-snapshot
Surprisingly extensive mixed phylogenetic and ecological signals among bacterial Operational Taxonomic Units
inferredcites →https://doi.org/10.1097/mcg.0000000000000046openalex-snapshot
Fecal Microbiota Transplantation for the Treatment of Clostridium difficile Infection
inferredcites →https://doi.org/10.1101/gr.085464.108openalex-snapshot
Microbial community profiling for human microbiome projects: Tools, techniques, and challenges
inferredcites →https://doi.org/10.1101/gr.096651.109openalex-snapshot
The NIH Human Microbiome Project
inferredcites →https://doi.org/10.1109/tnb.2015.2461219openalex-snapshot
Multi-Layer and Recursive Neural Networks for Metagenomic Classification
inferredcites →https://doi.org/10.1109/tpami.2013.50openalex-snapshot
Representation Learning: A Review and New Perspectives
inferredcites →https://doi.org/10.1111/j.1574-6976.2010.00251.xopenalex-snapshot
Supervised classification of human microbiota
inferredcites →https://doi.org/10.1126/science.1177486openalex-snapshot
Bacterial Community Variation in Human Body Habitats Across Space and Time
inferredcites →https://doi.org/10.1126/science.1241214openalex-snapshot
Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice
inferredcites →https://doi.org/10.1126/science.1261359openalex-snapshot
Structure and function of the global ocean microbiome
inferredcites →https://doi.org/10.1126/science.aac8455openalex-snapshot
The global ocean microbiome
inferredcites →https://doi.org/10.1126/scitranslmed.aab2271openalex-snapshot
Early infancy microbial and metabolic alterations affect risk of childhood asthma
inferredcites →https://doi.org/10.1128/aem.01541-09openalex-snapshot
Introducing mothur: Open-Source, Platform-Independent, Community-Supported Software for Describing and Comparing Microbial Communities
inferredcites →https://doi.org/10.1128/jcm.00162-17openalex-snapshot
Robust Microbiota-Based Diagnostics for Inflammatory Bowel Disease
inferredcites →https://doi.org/10.1128/jcm.01228-07openalex-snapshot
16S rRNA Gene Sequencing for Bacterial Identification in the Diagnostic Laboratory: Pluses, Perils, and Pitfalls
inferredcites →https://doi.org/10.1128/mbio.01012-14openalex-snapshot
Metatranscriptomics of the Human Oral Microbiome during Health and Disease
inferredcites →https://doi.org/10.1128/microbe.4.393.1openalex-snapshot
NIH Human Microbiome Project
inferredcites →https://doi.org/10.1136/gutjnl-2016-313235openalex-snapshot
A microbial signature for Crohn's disease
inferredcites →https://doi.org/10.1142/9789813235533_0018openalex-snapshot
Data-driven advice for applying machine learning to bioinformatics problems
inferredcites →https://doi.org/10.1186/1471-2164-14-641openalex-snapshot
Alignment-free supervised classification of metagenomes by recursive SVM
inferredcites →https://doi.org/10.1186/2049-2618-1-11openalex-snapshot
A comprehensive evaluation of multicategory classification methods for microbiomic data
inferredcites →https://doi.org/10.1186/gb-2014-15-3-r46openalex-snapshot
Kraken: ultrafast metagenomic sequence classification using exact alignments
inferredcites →https://doi.org/10.1186/s40168-015-0098-1openalex-snapshot
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inferredcites →https://doi.org/10.1371/journal.pbio.1002020openalex-snapshot
Life in a World without Microbes
inferredcites →https://doi.org/10.1371/journal.pcbi.1004977openalex-snapshot
Machine Learning Meta-analysis of Large Metagenomic Datasets: Tools and Biological Insights
inferredcites →https://doi.org/10.1371/journal.pcbi.1005518openalex-snapshot
ESPRIT-Forest: Parallel clustering of massive amplicon sequence data in subquadratic time
inferredcites →https://doi.org/10.1371/journal.pone.0073056openalex-snapshot
Metagenomic Predictions: From Microbiome to Complex Health and Environmental Phenotypes in Humans and Cattle
inferredcites →https://doi.org/10.1371/journal.pone.0087126openalex-snapshot
MetaMetaDB: A Database and Analytic System for Investigating Microbial Habitability
inferredcites →https://doi.org/10.1371/journal.pone.0121453openalex-snapshot
CoMeta: Classification of Metagenomes Using k-mers
inferredcites →https://doi.org/10.1371/journal.pone.0141287openalex-snapshot
Continuous Distributed Representation of Biological Sequences for Deep Proteomics and Genomics
inferredcites →https://doi.org/10.1371/journal.pone.0178338openalex-snapshot
Correction: Natalizumab stabilizes physical, cognitive, MRI, and OCT markers of disease activity: A prospective, non-randomized pilot study
inferredcites →https://doi.org/10.1378/chest.12-2854openalex-snapshot
The Airway Microbiome and Disease
inferredcites →https://doi.org/10.1681/asn.2013080905openalex-snapshot
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Principal Component Analysis
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Principal Component Analysis.
inferredcites →https://doi.org/10.4230/oasics.dx.2026.15openalex-snapshot
AutoResearch Lite: a reproducible paper-inspired experiment runner (Adam mechanism reproduction and convergence-speed comparison)
inferredcites →https://doi.org/10.48550/arxiv.1201.0490openalex-snapshot
Scikit-learn: Machine Learning in Python
inferredcites →https://doi.org/10.48550/arxiv.1412.6980openalex-snapshot
Adam: A Method for Stochastic Optimization
inferredcites →https://doi.org/10.7717/peerj.545openalex-snapshot
Subsampled open-reference clustering creates consistent, comprehensive OTU definitions and scales to billions of sequences

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1016/j.ymeth.2019.03.003openalex-snapshot
MetaPheno: A critical evaluation of deep learning and machine learning in metagenome-based disease prediction
inferred← citeshttps://doi.org/10.1038/s41598-022-04773-3openalex-snapshot
Multimodal deep learning applied to classify healthy and disease states of human microbiome
inferred← citeshttps://doi.org/10.1093/bioinformatics/bty954openalex-snapshot
DiTaxa: nucleotide-pair encoding of 16S rRNA for host phenotype and biomarker detection
inferred← citeshttps://doi.org/10.1101/419846openalex-snapshot
SpeciesMLP: Sequence based Multi-layer Perceptron for Amplicon Read Classification Using Real-time Data Augmentation
inferred← citeshttps://doi.org/10.1109/bibm.2018.8621287openalex-snapshot
AmpliconNet: Sequence Based Multi-layer Perceptron for Amplicon Read Classification Using Real-time Data Augmentation
inferred← citeshttps://doi.org/10.1109/cibec.2018.8641805openalex-snapshot
A Hybrid Machine Learning Approach for the Phenotypic Classification of Metagenomic Colon Cancer Reads Based on Kmer Frequency and Biomarker Profiling
inferred← citeshttps://doi.org/10.1371/journal.pcbi.1006721openalex-snapshot
16S rRNA sequence embeddings: Meaningful numeric feature representations of nucleotide sequences that are convenient for downstream analyses
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