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MDM4 is an essential disease driver targeted by 1q gain in Burkitt lymphoma
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/gcc.10155openalex-snapshot
DNA microarrays for comparative genomic hybridization based on DOP‐PCR amplification of BAC and PAC clones
inferredcites →https://doi.org/10.1002/ijc.27675openalex-snapshot
High‐throughput SNP‐based authentication of human cell lines
inferredcites →https://doi.org/10.1002/j.1460-2075.1991.tb07837.xopenalex-snapshot
p53 is frequently mutated in Burkitt's lymphoma cell lines.
inferredcites →https://doi.org/10.1006/geno.1997.4775openalex-snapshot
Isolation and Identification of the Human Homolog of a New p53-Binding Protein, Mdmx
inferredcites →https://doi.org/10.1007/978-1-61779-400-1_26openalex-snapshot
BiNGS!SL-seq: A Bioinformatics Pipeline for the Analysis and Interpretation of Deep Sequencing Genome-Wide Synthetic Lethal Screen
inferredcites →https://doi.org/10.1016/0092-8674(92)90123-topenalex-snapshot
Induction of apoptosis in fibroblasts by c-myc protein
inferredcites →https://doi.org/10.1016/j.ccell.2016.10.002openalex-snapshot
A Druggable TCF4- and BRD4-Dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm
inferredcites →https://doi.org/10.1016/j.ccr.2012.07.014openalex-snapshot
Integrative Analysis Reveals an Outcome-Associated and Targetable Pattern of p53 and Cell Cycle Deregulation in Diffuse Large B Cell Lymphoma
inferredcites →https://doi.org/10.1016/j.cell.2015.11.062openalex-snapshot
Functional Genomic Landscape of Human Breast Cancer Drivers, Vulnerabilities, and Resistance
inferredcites →https://doi.org/10.1016/j.cell.2017.06.010openalex-snapshot
Defining a Cancer Dependency Map
inferredcites →https://doi.org/10.1016/j.semcancer.2006.07.011openalex-snapshot
The Oscar-worthy role of Myc in apoptosis
inferredcites →https://doi.org/10.1038/cddis.2015.173openalex-snapshot
Targeting Mdmx to treat breast cancers with wild-type p53
inferredcites →https://doi.org/10.1038/cgt.2010.63openalex-snapshot
Understanding wild-type and mutant p53 activities in human cancer: new landmarks on the way to targeted therapies
inferredcites →https://doi.org/10.1038/leu.2016.230openalex-snapshot
Dissection of CD20 regulation in lymphoma using RNAi
inferredcites →https://doi.org/10.1038/nature03845openalex-snapshot
Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants
inferredcites →https://doi.org/10.1038/nature08822openalex-snapshot
The landscape of somatic copy-number alteration across human cancers
inferredcites →https://doi.org/10.1038/nature09504openalex-snapshot
Selective inhibition of BET bromodomains
inferredcites →https://doi.org/10.1038/nature09671openalex-snapshot
Oncogenically active MYD88 mutations in human lymphoma
inferredcites →https://doi.org/10.1038/nature11003openalex-snapshot
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
inferredcites →https://doi.org/10.1038/nature11378openalex-snapshot
Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics
inferredcites →https://doi.org/10.1038/nature21076openalex-snapshot
Metabolic gatekeeper function of B-lymphoid transcription factors
inferredcites →https://doi.org/10.1038/ncb3380openalex-snapshot
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer
inferredcites →https://doi.org/10.1038/ng.2468openalex-snapshot
The genetic landscape of mutations in Burkitt lymphoma
inferredcites →https://doi.org/10.1038/ng.2469openalex-snapshot
Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing
inferredcites →https://doi.org/10.1038/ng.3413openalex-snapshot
DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control
inferredcites →https://doi.org/10.1038/ng1180openalex-snapshot
PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
inferredcites →https://doi.org/10.1038/nm.2863openalex-snapshot
MDM4 is a key therapeutic target in cutaneous melanoma
inferredcites →https://doi.org/10.1038/nm.3480openalex-snapshot
ARID1B is a specific vulnerability in ARID1A-mutant cancers
inferredcites →https://doi.org/10.1038/nm.4204openalex-snapshot
Recurrent MET fusion genes represent a drug target in pediatric glioblastoma
inferredcites →https://doi.org/10.1038/nmeth.3047openalex-snapshot
Improved vectors and genome-wide libraries for CRISPR screening
inferredcites →https://doi.org/10.1038/nrc1947openalex-snapshot
Lineage dependency and lineage-survival oncogenes in human cancer
inferredcites →https://doi.org/10.1038/nrm3860openalex-snapshot
RNAi screening comes of age: improved techniques and complementary approaches
inferredcites →https://doi.org/10.1038/sdata.2014.35openalex-snapshot
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies
inferredcites →https://doi.org/10.1038/sj.onc.1203590openalex-snapshot
Epo regulates erythroid proliferation and differentiation through distinct signaling pathways: implication for erythropoiesis and Friend virus-induced erythroleukemia
inferredcites →https://doi.org/10.1038/sj.onc.1204303openalex-snapshot
p14ARF homozygous deletion or MDM2 overexpression in Burkitt lymphoma lines carrying wild type p53
inferredcites →https://doi.org/10.1038/sj.onc.1211010openalex-snapshot
Chaperone-dependent stabilization and degradation of p53 mutants
inferredcites →https://doi.org/10.1056/nejmc1012718openalex-snapshot
p53 Lesions in Leukemic Transformation
inferredcites →https://doi.org/10.1056/nejmoa055351openalex-snapshot
A Biologic Definition of Burkitt's Lymphoma from Transcriptional and Genomic Profiling
inferredcites →https://doi.org/10.1073/pnas.0304717101openalex-snapshot
Automated array-based genomic profiling in chronic lymphocytic leukemia: Development of a clinical tool and discovery of recurrent genomic alterations
inferredcites →https://doi.org/10.1073/pnas.0506580102openalex-snapshot
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
inferredcites →https://doi.org/10.1073/pnas.1109363108openalex-snapshot
Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer
inferredcites →https://doi.org/10.1073/pnas.1203789109openalex-snapshot
Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization
inferredcites →https://doi.org/10.1073/pnas.2030930100openalex-snapshot
HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53
inferredcites →https://doi.org/10.1073/pnas.79.24.7824openalex-snapshot
Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells.
inferredcites →https://doi.org/10.1073/pnas.79.24.7837openalex-snapshot
Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells.
inferredcites →https://doi.org/10.1073/pnas.88.12.5413openalex-snapshot
p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia.
inferredcites →https://doi.org/10.1073/pnas.93.16.8379openalex-snapshot
Mutant conformation of p53 translated in vitro or in vivo requires functional HSP90.
inferredcites →https://doi.org/10.1074/jbc.c600147200openalex-snapshot
MDMX Overexpression Prevents p53 Activation by the MDM2 Inhibitor Nutlin
inferredcites →https://doi.org/10.1093/nar/gkp581openalex-snapshot
High-throughput detection and multiplex identification of cell contaminations
inferredcites →https://doi.org/10.1126/science.1092472openalex-snapshot
In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2
inferredcites →https://doi.org/10.1126/science.aac7041openalex-snapshot
Identification and characterization of essential genes in the human genome
inferredcites →https://doi.org/10.1128/jvi.02408-08openalex-snapshot
Epstein-Barr Virus Nuclear Antigen 3C Augments Mdm2-Mediated p53 Ubiquitination and Degradation by Deubiquitinating Mdm2
inferredcites →https://doi.org/10.1158/0008-5472.can-05-3832openalex-snapshot
Levels of HdmX Expression Dictate the Sensitivity of Normal and Transformed Cells to Nutlin-3
inferredcites →https://doi.org/10.1158/1078-0432.ccr-07-4129openalex-snapshot
High-Resolution Array-Based Comparative Genomic Hybridization of Bladder Cancers Identifies Mouse Double Minute 4 ( MDM4 ) as an Amplification Target Exclusive of MDM2 and TP53
inferredcites →https://doi.org/10.1158/1541-7786.mcr-10-0534openalex-snapshot
Functional Inactivation of Endogenous MDM2 and CHIP by HSP90 Causes Aberrant Stabilization of Mutant p53 in Human Cancer Cells
inferredcites →https://doi.org/10.1172/jci30842openalex-snapshot
B cell activator PAX5 promotes lymphomagenesis through stimulation of B cell receptor signaling
inferredcites →https://doi.org/10.1172/jci93801openalex-snapshot
Drug-perturbation-based stratification of blood cancer
inferredcites →https://doi.org/10.1182/blood-2017-07-796821openalex-snapshot
EBV latent membrane protein 2A orchestrates p27kip1 degradation via Cks1 to accelerate MYC-driven lymphoma in mice
inferredcites →https://doi.org/10.1200/jco.2009.27.8762openalex-snapshot
TP53 Mutation and Survival in Chronic Lymphocytic Leukemia
inferredcites →https://doi.org/10.12688/f1000research.3928.1openalex-snapshot
shRNA-seq data analysis with edgeR
inferredcites →https://doi.org/10.1371/journal.pone.0007089openalex-snapshot
High Resolution Genome-Wide Analysis of Chromosomal Alterations in Burkitt's Lymphoma
inferredcites →https://doi.org/10.1371/journal.pone.0023569openalex-snapshot
Apoptosis Induced by Piroxicam plus Cisplatin Combined Treatment Is Triggered by p21 in Mesothelioma
inferredcites →https://doi.org/10.15252/msb.20145216openalex-snapshot
Measuring error rates in genomic perturbation screens: gold standards for human functional genomics
inferredcites →https://doi.org/10.17863/cam.20903openalex-snapshot
Drug-perturbation-based stratification of blood cancer
inferredcites →https://doi.org/10.18632/aging.100008openalex-snapshot
Alterations in gene expression and sensitivity to genotoxic stress following HdmX or Hdm2 knockdown in human tumor cells harboring wild-type p53
inferredcites →https://doi.org/10.2174/187152809787582525openalex-snapshot
Role of Fc Receptors as a Therapeutic Target
inferredcites →https://doi.org/10.3109/10428194.2013.796053openalex-snapshot
Next-generation sequencing of cancer consensus genes in lymphoma
inferredcites →https://doi.org/10.3324/haematol.13071openalex-snapshot
Chromosomal alterations detected by comparative genomic hybridization in subgroups of gene expression-defined Burkitt's lymphoma
inferredcites →https://doi.org/10.3324/haematol.2010.026831openalex-snapshot
Detection of genomic aberrations in molecularly defined Burkitt's lymphoma by array-based, high resolution, single nucleotide polymorphism analysis
inferredcites →https://doi.org/10.3324/haematol.2016.142976openalex-snapshot
Targeted positron emission tomography imaging of CXCR4 expression in patients with acute myeloid leukemia
inferredcites →https://doi.org/10.3389/fonc.2015.00284openalex-snapshot
Regulation of Mutant p53 Protein Expression
inferredcites →https://doi.org/10.3389/fonc.2016.00007openalex-snapshot
Clinical Overview of MDM2/X-Targeted Therapies
inferredcites →https://doi.org/10.4049/jimmunol.181.3.1644openalex-snapshot
The Transcription Factor Fli-1 Modulates Marginal Zone and Follicular B Cell Development in Mice
inferredcites →https://doi.org/10.4161/15384101.2014.950132openalex-snapshot
Proteasome inhibitors suppress the protein expression of mutant p53
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.15252/emmm.201809889openalex-snapshot
Requirement for YAP1 signaling in myxoid liposarcoma
inferred← citeshttps://doi.org/10.53846/goediss-9752openalex-snapshot
Vergleichende immunhistochemische Analyse onkogener Signalwegssignaturen in Lymphomen
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