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Mesenchymal stromal cell remodeling of a gelatin hydrogel microenvironment defines an artificial hematopoietic stem cell niche

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Culture materials affectex vivo expansion of hematopoietic progenitor cells

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Microfluidic Generation of Gradient Hydrogels to Modulate Hematopoietic Stem Cell Culture Environment

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Hydration and density of collagen and gelatin

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Poly(vinyl alcohol) hydrogels. Formation by electron beam irradiation of aqueous solutions and subsequent crystallization

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Crosslinked poly(vinyl alcohol) hydrogels as swollen elastic networks

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Engineering the hematopoietic stem cell niche: Frontiers in biomaterial science

inferredcites →https://doi.org/10.1002/bip.10427openalex-snapshot

Molecular weight effects on the glass transition of gelatin/cosolute mixtures

inferredcites →https://doi.org/10.1002/bit.25848openalex-snapshot

Bioactive poly(ethylene glycol) hydrogels to recapitulate the HSC niche and facilitate HSC expansion in culture

inferredcites →https://doi.org/10.1002/cyto.a.20674openalex-snapshot

Mouse hematopoietic stem cell identification and analysis

inferredcites →https://doi.org/10.1002/cyto.a.22093openalex-snapshot

Flow cytometry analysis of murine hematopoietic stem cells

inferredcites →https://doi.org/10.1002/cyto.b.21066openalex-snapshot

The hematopoietic stem cell niche—home for friend and foe?

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Correlation between mesh size and equilibrium degree of swelling of polymeric networks

inferredcites →https://doi.org/10.1002/jbm.a.30916openalex-snapshot

Biomaterial‐based notch signaling for the differentiation of hematopoietic stem cells into T cells

inferredcites →https://doi.org/10.1002/jbm.a.34637openalex-snapshot

Impact of the biophysical features of a 3D gelatin microenvironment on glioblastoma malignancy

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The Combined Influence of Hydrogel Stiffness and Matrix‐Bound Hyaluronic Acid Content on Glioblastoma Invasion

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Physical Techniques for the Study of Food Biopolymers

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From Interatomic Interactions to Protein Structure

inferredcites →https://doi.org/10.1007/s00277-016-2608-zopenalex-snapshot

Purification of hematopoietic stem cells from bone marrow

inferredcites →https://doi.org/10.1016/0032-3861(91)90143-7openalex-snapshot

Conformation of gelatin chains in aqueous solutions: 1. A light and small-angle neutron scattering study

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A note on levene's tests for equality of variances

inferredcites →https://doi.org/10.1016/0198-9715(90)90050-4openalex-snapshot

Statistical power analysis for the behavioral sciences

inferredcites →https://doi.org/10.1016/j.actbio.2013.08.012openalex-snapshot

Covalent immobilization of stem cell factor and stromal derived factor 1α for in vitro culture of hematopoietic progenitor cells

inferredcites →https://doi.org/10.1016/j.biomaterials.2012.01.002openalex-snapshot

The significance of integrin ligand nanopatterning on lipid raft clustering in hematopoietic stem cells

inferredcites →https://doi.org/10.1016/j.biomaterials.2013.06.024openalex-snapshot

Regulation of glioma cell phenotype in 3D matrices by hyaluronic acid

inferredcites →https://doi.org/10.1016/j.biomaterials.2015.07.042openalex-snapshot

The use of covalently immobilized stem cell factor to selectively affect hematopoietic stem cell activity within a gelatin hydrogel

inferredcites →https://doi.org/10.1016/j.biomaterials.2016.01.050openalex-snapshot

Enzyme responsive GAG-based natural-synthetic hybrid hydrogel for tunable growth factor delivery and stem cell differentiation

inferredcites →https://doi.org/10.1016/j.biomaterials.2017.02.013openalex-snapshot

Regulating dynamic signaling between hematopoietic stem cells and niche cells via a hydrogel matrix

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Diffusion of Particles in the Extracellular Matrix: The Effect of Repulsive Electrostatic Interactions

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Stromal dynamic reciprocity in cancer: intricacies of fibroblastic-ECM interactions

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Quiescence regulators for hematopoietic stem cell

inferredcites →https://doi.org/10.1016/j.exphem.2013.11.013openalex-snapshot

Flk2/Flt3 promotes both myeloid and lymphoid development by expanding non–self-renewing multipotent hematopoietic progenitor cells

inferredcites →https://doi.org/10.1016/j.immuni.2006.10.016openalex-snapshot

Maintenance of the Hematopoietic Stem Cell Pool by CXCL12-CXCR4 Chemokine Signaling in Bone Marrow Stromal Cell Niches

inferredcites →https://doi.org/10.1016/j.it.2013.10.002openalex-snapshot

Regulation of hematopoietic stem cells by bone marrow stromal cells

inferredcites →https://doi.org/10.1016/j.jmbbm.2015.06.023openalex-snapshot

Mechanics of intact bone marrow

inferredcites →https://doi.org/10.1016/j.stem.2012.01.003openalex-snapshot

Rapid Expansion of Human Hematopoietic Stem Cells by Automated Control of Inhibitory Feedback Signaling

inferredcites →https://doi.org/10.1016/j.stem.2012.01.006openalex-snapshot

Hematopoiesis: A Human Perspective

inferredcites →https://doi.org/10.1016/j.talanta.2004.06.029openalex-snapshot

Density measurements of potassium phosphate buffer from 4 to 45�C

inferredcites →https://doi.org/10.1016/j.yexcr.2006.12.019openalex-snapshot

Phagocytosis and remodeling of collagen matrices

inferredcites →https://doi.org/10.1016/j.yexcr.2014.03.003openalex-snapshot

Defining the role of mesenchymal stromal cells on the regulation of matrix metalloproteinases in skeletal muscle cells

inferredcites →https://doi.org/10.1016/j.yexcr.2014.08.017openalex-snapshot

Pro-inflammatory cytokines: Emerging players regulating HSC function in normal and diseased hematopoiesis

inferredcites →https://doi.org/10.1016/s0006-3495(99)76911-0openalex-snapshot

Diffusion of Macromolecules in Agarose Gels: Comparison of Linear and Globular Configurations

inferredcites →https://doi.org/10.1016/s0022-2836(62)80034-5openalex-snapshot

Ultracentrifugal observation of phase transitions in density gradients

inferredcites →https://doi.org/10.1021/ac60052a025openalex-snapshot

Simplified Statistics for Small Numbers of Observations

inferredcites →https://doi.org/10.1021/acs.analchem.5b02537openalex-snapshot

Identifying States along the Hematopoietic Stem Cell Differentiation Hierarchy with Single Cell Specificity via Raman Spectroscopy

inferredcites →https://doi.org/10.1021/acs.biomac.7b00118openalex-snapshot

Patterning Three-Dimensional Hydrogel Microenvironments Using Hyperbranched Polyglycerols for Independent Control of Mesh Size and Stiffness

inferredcites →https://doi.org/10.1021/bm0492430openalex-snapshot

Flory Temperature and Upper Critical Solution Temperature of Gelatin Solutions

inferredcites →https://doi.org/10.1023/a:1016029023910openalex-snapshot

Chemical and Swelling Evaluations of Amino Group Crosslinking in Gelatin and Modified Gelatin Matrices

inferredcites →https://doi.org/10.1037/0033-2909.112.1.155openalex-snapshot

A power primer.

inferredcites →https://doi.org/10.1038/nature09262openalex-snapshot

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

inferredcites →https://doi.org/10.1038/nature12984openalex-snapshot

The bone marrow niche for haematopoietic stem cells

inferredcites →https://doi.org/10.1038/nbt.1687openalex-snapshot

Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells

inferredcites →https://doi.org/10.1038/ncb2730openalex-snapshot

Quantitative imaging of haematopoietic stem and progenitor cell localization and hypoxic status in the bone marrow microenvironment

inferredcites →https://doi.org/10.1038/ni1331openalex-snapshot

The hematopoietic stem cell in its place

inferredcites →https://doi.org/10.1038/nm.3647openalex-snapshot

Hematopoietic stem cell niche maintenance during homeostasis and regeneration

inferredcites →https://doi.org/10.1038/nri1779openalex-snapshot

Bone-marrow haematopoietic-stem-cell niches

inferredcites →https://doi.org/10.1038/nrm2125openalex-snapshot

Matrix metalloproteinases and the regulation of tissue remodelling

inferredcites →https://doi.org/10.1038/s41598-017-02352-5openalex-snapshot

Bone marrow niche-mimetics modulate HSPC function via integrin signaling

inferredcites →https://doi.org/10.1038/sj.thj.6200232openalex-snapshot

Mesenchymal stem cell: use and perspectives

inferredcites →https://doi.org/10.1038/srep31951openalex-snapshot

Distinguishing autocrine and paracrine signals in hematopoietic stem cell culture using a biofunctional microcavity platform

inferredcites →https://doi.org/10.1039/c2sm06825gopenalex-snapshot

From macro- to microscale poroelastic characterization of polymeric hydrogels via indentation

inferredcites →https://doi.org/10.1039/c6sm02341jopenalex-snapshot

Unified solution for poroelastic oscillation indentation on gels for spherical, conical and cylindrical indenters

inferredcites →https://doi.org/10.1056/nejmra052638openalex-snapshot

Hematopoietic Stem-Cell Transplantation

inferredcites →https://doi.org/10.1063/1.1723792openalex-snapshot

Statistical Mechanics of Cross-Linked Polymer Networks II. Swelling

inferredcites →https://doi.org/10.1063/1.3370354openalex-snapshot

Using indentation to characterize the poroelasticity of gels

inferredcites →https://doi.org/10.1073/pnas.1511304112openalex-snapshot

Measuring dynamic cell–material interactions and remodeling during 3D human mesenchymal stem cell migration in hydrogels

inferredcites →https://doi.org/10.1074/jbc.r700043200openalex-snapshot

Stem Cell Niche: Microenvironment and Beyond

inferredcites →https://doi.org/10.1080/10255842.2011.554409openalex-snapshot

A reaction–diffusion model to predict the influence of neo-matrix on the subsequent development of tissue-engineered cartilage

inferredcites →https://doi.org/10.1083/jcb.201102131openalex-snapshot

Cell cycle regulation in hematopoietic stem cells

inferredcites →https://doi.org/10.1084/jem.20110132openalex-snapshot

The bone marrow stem cell niche grows up: mesenchymal stem cells and macrophages move in

inferredcites →https://doi.org/10.1089/ten.tea.2008.0545openalex-snapshot

Photocrosslinking of Gelatin Macromers to Synthesize Porous Hydrogels That Promote Valvular Interstitial Cell Function

inferredcites →https://doi.org/10.1093/nar/gkp1005openalex-snapshot

PrimerBank: a resource of human and mouse PCR primer pairs for gene expression detection and quantification

inferredcites →https://doi.org/10.1093/nar/gng154openalex-snapshot

A PCR primer bank for quantitative gene expression analysis

inferredcites →https://doi.org/10.1111/j.1524-475x.2011.00673.xopenalex-snapshot

Dynamic reciprocity in the wound microenvironment

inferredcites →https://doi.org/10.1126/sciadv.1600455openalex-snapshot

Marrow-inspired matrix cues rapidly affect early fate decisions of hematopoietic stem and progenitor cells

inferredcites →https://doi.org/10.1126/science.2898810openalex-snapshot

Purification and Characterization of Mouse Hematopoietic Stem Cells

inferredcites →https://doi.org/10.1155/2011/353878openalex-snapshot

Paracrine Molecules of Mesenchymal Stem Cells for Hematopoietic Stem Cell Niche

inferredcites →https://doi.org/10.1177/002215549804600311openalex-snapshot

Immunofluorescence Characterization of Key Extracellular Matrix Proteins in Murine Bone Marrow In Situ

inferredcites →https://doi.org/10.1182/blood-2004-06-2159openalex-snapshot

Identification of Lin–Sca1+kit+CD34+Flt3– short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients

inferredcites →https://doi.org/10.1182/blood-2012-02-412379openalex-snapshot

Stress hematopoiesis reveals abnormal control of self-renewal, lineage bias, and myeloid differentiation in Mll partial tandem duplication (Mll-PTD) hematopoietic stem/progenitor cells

inferredcites →https://doi.org/10.1182/blood.v80.12.3044.3044openalex-snapshot

In vivo and in vitro stem cell function of c-kit- and Sca-1-positive murine hematopoietic cells

inferredcites →https://doi.org/10.1182/blood.v81.11.2844.2844openalex-snapshot

Differentiation and proliferation of hematopoietic stem cells

inferredcites →https://doi.org/10.1182/blood.v97.10.3075openalex-snapshot

Numerous growth factors, cytokines, and chemokines are secreted by human CD34+ cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner

inferredcites →https://doi.org/10.1186/1471-2105-13-134openalex-snapshot

Primer-BLAST: A tool to design target-specific primers for polymerase chain reaction

inferredcites →https://doi.org/10.1186/1471-2164-9-633openalex-snapshot

A comprehensive collection of experimentally validated primers for Polymerase Chain Reaction quantitation of murine transcript abundance

inferredcites →https://doi.org/10.1242/dev.106575openalex-snapshot

The analysis, roles and regulation of quiescence in hematopoietic stem cells

inferredcites →https://doi.org/10.1242/jcs.006064openalex-snapshot

Extracellular matrix dynamics in development and regenerative medicine

inferredcites →https://doi.org/10.1242/jcs.095596openalex-snapshot

Impact of substrate elasticity on human hematopoietic stem and progenitor cell adhesion and motility

inferredcites →https://doi.org/10.1557/jmr.2010.35openalex-snapshot

Indentation of polydimethylsiloxane submerged in organic solvents

inferredcites →https://doi.org/10.1634/stemcells.19-2-99openalex-snapshot

Autocrine/Paracrine Mechanisms in Human Hematopoiesis

inferredcites →https://doi.org/10.1634/stemcells.2007-0280openalex-snapshot

Molecular and Secretory Profiles of Human Mesenchymal Stromal Cells and Their Abilities to Maintain Primitive Hematopoietic Progenitors

inferredcites →https://doi.org/10.2174/156652412798376125openalex-snapshot

Hematopoietic Stem Cells: Transcriptional Regulation, Ex Vivo Expansion and Clinical Application

inferredcites →https://doi.org/10.4172/2157-7633.1000225openalex-snapshot

Mesenchymal Stem Cells: Pivotal Players in Hematopoietic Stem Cell Microenvironment

inferredcites →https://doi.org/10.5812/ijem.3505openalex-snapshot

Normality Tests for Statistical Analysis: A Guide for Non-Statisticians

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.3390/biomedicines9050574openalex-snapshot

Deciphering the Molecular Mechanism of Water Interaction with Gelatin Methacryloyl Hydrogels: Role of Ionic Strength, pH, Drug Loading and Hydrogel Network Characteristics

inferred← citeshttps://doi.org/10.3390/ijms24054957openalex-snapshot

In Situ Formation of Injectable Gelatin Methacryloyl (GelMA) Hydrogels for Effective Intraocular Delivery of Triamcinolone Acetonide

inferred← citeshttps://doi.org/10.3390/polym13223960openalex-snapshot

Gelatin Methacryloyl Hydrogels for the Localized Delivery of Cefazolin

inferred← citeshttps://doi.org/10.5204/thesis.eprints.212857openalex-snapshot

Photocrosslinkable hydrogels for controlled local drug delivery

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