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Characterisation of palytoxin from an undescribed Palythoa (Anthozoa: Zoantharia: Sphenopidae) with significant in vitro cytotoxic effects on cancer cells at picomolar doses

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1001/archophthalmol.2010.206openalex-snapshot

Aquarium Coral Keratoconjunctivitis

inferredcites →https://doi.org/10.1002/cncr.10710openalex-snapshot

Evaluation of the efficiency of chemotherapy in in vivo orthotopic models of human glioma cells with and without 1p19q deletions and in C6 rat orthotopic allografts serving for the evaluation of surgery combined with chemotherapy

inferredcites →https://doi.org/10.1002/jps.2600630217openalex-snapshot

Anticancer Activity of Zoanthids and the Associated Toxin, Palytoxin, against Ehrlich Ascites Tumor and P-388 Lymphocytic Leukemia in Mice

inferredcites →https://doi.org/10.1002/path.2172openalex-snapshot

The α1 subunit of the sodium pump could represent a novel target to combat non‐small cell lung cancers

inferredcites →https://doi.org/10.1002/rcm.5264openalex-snapshot

Preliminary study for rapid determination of phycotoxins in microalgae whole cells using matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry

inferredcites →https://doi.org/10.1007/978-94-009-6735-9_32openalex-snapshot

Immunological and Molecular Heterogeneity of Heat-Labile Enterotoxins from Human and Porcine Enterotoxigenic Escherichia Coli

inferredcites →https://doi.org/10.1007/bf00503920openalex-snapshot

Ouabain inhibits the increase due to palytoxin of cation permeability of erythrocytes

inferredcites →https://doi.org/10.1007/bf02759164openalex-snapshot

Point amino acid substitutions in the Ca2+-binding sites of recoverin: III. A mutant with the fourth reconstructed Ca2+-binding site

inferredcites →https://doi.org/10.1007/bf02759168openalex-snapshot

An enzyme linked immunosorbent assay for detecting palytoxin-producing bacteria

inferredcites →https://doi.org/10.1007/s003380050060openalex-snapshot

Zoanthids (Anthozoa, Hexacorallia) from the Great Barrier Reef and Torres Strait, Australia: systematics, evolution and a key to species

inferredcites →https://doi.org/10.1007/s10482-009-9353-4openalex-snapshot

Detection of hemolytic bacteria from Palythoa caribaeorum (Cnidaria, Zoantharia) using a novel palytoxin-screening assay

inferredcites →https://doi.org/10.1016/0041-0101(74)90011-7openalex-snapshot

Toxicological evaluation of palytoxin in several animal species

inferredcites →https://doi.org/10.1016/0041-0101(83)90013-2openalex-snapshot

A method for the isolation of the caribbean palytoxin (C-PTX) from the coelenterate (zooanthid) Palythoa caribaeorum

inferredcites →https://doi.org/10.1016/0041-0101(93)90172-fopenalex-snapshot

Isolation of zooxanthellatoxins, novel vasoconstrictive substances from the zooxanthella Symbiodinium sp

inferredcites →https://doi.org/10.1016/0041-0101(95)00010-jopenalex-snapshot

Interaction of palytoxin with red cells: Structure-function studies

inferredcites →https://doi.org/10.1016/0041-0101(95)00079-2openalex-snapshot

Studies on the origin and distribution of palytoxin in a Caribbean coral reef

inferredcites →https://doi.org/10.1016/j.bbcan.2007.06.002openalex-snapshot

Cardiotonic steroids on the road to anti-cancer therapy

inferredcites →https://doi.org/10.1016/j.jasms.2007.11.001openalex-snapshot

Putative palytoxin and its new analogue, ovatoxin-a, in Ostreopsis ovata collected along the ligurian coasts during the 2006 toxic outbreak

inferredcites →https://doi.org/10.1016/j.jemermed.2009.05.004openalex-snapshot

Palytoxin Poisoning After Dermal Contact with Zoanthid Coral

inferredcites →https://doi.org/10.1016/j.tiv.2008.04.012openalex-snapshot

Characteristics of palytoxin-induced cytotoxicity in neuroblastoma cells

inferredcites →https://doi.org/10.1016/j.toxicon.2003.10.012openalex-snapshot

Identification of palytoxin as a principle which causes morphological changes in rat 3Y1 cells in the zoanthid Palythoa aff. margaritae

inferredcites →https://doi.org/10.1016/j.toxicon.2008.12.005openalex-snapshot

Suitability of the Neuro-2a cell line for the detection of palytoxin and analogues (neurotoxic phycotoxins)

inferredcites →https://doi.org/10.1016/j.toxicon.2010.08.003openalex-snapshot

New palytoxin-like molecules in Mediterranean Ostreopsis cf. ovata (dinoflagellates) and in Palythoa tuberculosa detected by liquid chromatography-electrospray ionization time-of-flight mass spectrometry

inferredcites →https://doi.org/10.1016/j.toxicon.2010.09.011openalex-snapshot

Palytoxin action on the Na+,K+-ATPase and the disruption of ion equilibria in biological systems

inferredcites →https://doi.org/10.1016/j.toxicon.2010.09.017openalex-snapshot

Palytoxins and cytoskeleton: An overview

inferredcites →https://doi.org/10.1016/j.toxicon.2010.11.003openalex-snapshot

Modulation of protein kinase signaling cascades by palytoxin

inferredcites →https://doi.org/10.1016/j.toxicon.2015.09.001openalex-snapshot

Dangerous reef aquaristics: Palytoxin of a brown encrusting anemone causes toxic corneal reactions

inferredcites →https://doi.org/10.1016/j.toxicon.2015.12.004openalex-snapshot

Distribution of palytoxin in coral reef organisms living in close proximity to an aggregation of Palythoa tuberculosa

inferredcites →https://doi.org/10.1016/j.toxicon.2016.08.012openalex-snapshot

An aquarium hobbyist poisoning: Identification of new palytoxins in Palythoa cf. toxica and complete detoxification of the aquarium water by activated carbon

inferredcites →https://doi.org/10.1016/j.toxlet.2013.12.020openalex-snapshot

In vivo and in vitro effects of 42-hydroxy-palytoxin on mouse skeletal muscle: Structural and functional impairment

inferredcites →https://doi.org/10.1016/j.yexcr.2008.06.010openalex-snapshot

Videomicroscopic extraction of specific information on cell proliferation and migration in vitro

inferredcites →https://doi.org/10.1016/s0014-2999(03)01459-6openalex-snapshot

Palytoxin-induced increase in cytosolic-free Ca2+ in mouse spleen cells

inferredcites →https://doi.org/10.1016/s0022-5347(05)68629-6openalex-snapshot

REDUCED EXPRESSION OF beta-SUBUNIT OF NA,K-ATPASE IN HUMAN CLEAR-CELL RENAL CELL CARCINOMA

inferredcites →https://doi.org/10.1016/s0040-4020(01)96468-3openalex-snapshot

Studies on palytoxins

inferredcites →https://doi.org/10.1017/s0025315414000654openalex-snapshot

Ascension Island shallow-water Zoantharia (Hexacorallia: Cnidaria) and their zooxanthellae (Symbiodinium)

inferredcites →https://doi.org/10.1021/bk-1990-0418openalex-snapshot

Marine Toxins

inferredcites →https://doi.org/10.1021/bk-1990-0418.ch008openalex-snapshot

Polyether Toxins Involved in Seafood Poisoning

inferredcites →https://doi.org/10.1021/jm8013585openalex-snapshot

Structure−Activity Relationship Analysis of Novel Derivatives of Narciclasine (an Amaryllidaceae Isocarbostyril Derivative) as Potential Anticancer Agents

inferredcites →https://doi.org/10.1021/np4009514openalex-snapshot

Stereoisomers of 42-Hydroxy Palytoxin from Hawaiian Palythoa toxica and P. tuberculosa: Stereostructure Elucidation, Detection, and Biological Activities

inferredcites →https://doi.org/10.1021/tx300203xopenalex-snapshot

The Stretch-Activated Channel Blocker Gd3+Reduces Palytoxin Toxicity in Primary Cultures of Skeletal Muscle Cells

inferredcites →https://doi.org/10.1021/tx900259vopenalex-snapshot

Stereostructure and Biological Activity of 42-Hydroxy-palytoxin: A New Palytoxin Analogue from HawaiianPalythoaSubspecies

inferredcites →https://doi.org/10.1038/ncomms12336openalex-snapshot

Synergistic effects of ion transporter and MAP kinase pathway inhibitors in melanoma

inferredcites →https://doi.org/10.1038/nrclinonc.2016.60openalex-snapshot

Cancer metabolism: a therapeutic perspective

inferredcites →https://doi.org/10.1073/pnas.90.19.8881openalex-snapshot

The amino-terminal 200 amino acids of the plasma membrane Na+,K+-ATPase alpha subunit confer ouabain sensitivity on the sarcoplasmic reticulum Ca(2+)-ATPase.

inferredcites →https://doi.org/10.1074/jbc.m111357200openalex-snapshot

Src-mediated Inter-receptor Cross-talk between the Na+/K+-ATPase and the Epidermal Growth Factor Receptor Relays the Signal from Ouabain to Mitogen-activated Protein Kinases

inferredcites →https://doi.org/10.1085/jgp.200308964openalex-snapshot

Large Diameter of Palytoxin-induced Na/K Pump Channels and Modulation of Palytoxin Interaction by Na/K Pump Ligands

inferredcites →https://doi.org/10.1093/bioinformatics/14.9.817openalex-snapshot

MODELTEST: testing the model of DNA substitution.

inferredcites →https://doi.org/10.1093/bioinformatics/btg180openalex-snapshot

MrBayes 3: Bayesian phylogenetic inference under mixed models

inferredcites →https://doi.org/10.1093/carcin/7.5.707openalex-snapshot

Palytoxin is a non-12-O-tetradecanoylphorbol-13-acetate type tumor promoter in two-stage mouse skin carcinogenesis

inferredcites →https://doi.org/10.1093/molbev/mst197openalex-snapshot

MEGA6: Molecular Evolutionary Genetics Analysis Version 6.0

inferredcites →https://doi.org/10.1093/nar/gkh340openalex-snapshot

MUSCLE: multiple sequence alignment with high accuracy and high throughput

inferredcites →https://doi.org/10.1096/fj.10-162263openalex-snapshot

Targeting of eEF1A with Amaryllidaceae isocarbostyrils as a strategy to combat melanomas

inferredcites →https://doi.org/10.1111/j.1365-3040.2006.001587.xopenalex-snapshot

The impact of coral bleaching on the pigment profile of the symbiotic alga, Symbiodinium

inferredcites →https://doi.org/10.1111/j.1476-5381.1980.tb10975.xopenalex-snapshot

THE POTENT DEPOLARIZING ACTION OF PALYTOXIN ISOLATED FROM Palythoa Tubercurosa ON THE ISOLATED SPINAL CORD OF THE FROG

inferredcites →https://doi.org/10.1111/j.1529-8817.2004.04016.xopenalex-snapshot

FIRST EVIDENCE OF PALYTOXIN ANALOGUES FROM ANOSTREOPSIS MASCARENENSIS(DINOPHYCEAE) BENTHIC BLOOM IN SOUTHWESTERN INDIAN OCEAN1

inferredcites →https://doi.org/10.1111/j.1742-4658.2008.06712.xopenalex-snapshot

Marine toxins and the cytoskeleton: a new view of palytoxin toxicity

inferredcites →https://doi.org/10.1126/science.172.3982.495openalex-snapshot

Palytoxin: A New Marine Toxin from a Coelenterate

inferredcites →https://doi.org/10.1152/ajpcell.00254.2006openalex-snapshot

Palytoxin: exploiting a novel skin tumor promoter to explore signal transduction and carcinogenesis

inferredcites →https://doi.org/10.1152/ajpcell.2001.281.4.c1336openalex-snapshot

All human Na+-K+-ATPase α-subunit isoforms have a similar affinity for cardiac glycosides

inferredcites →https://doi.org/10.1155/2012/856079openalex-snapshot

Species Diversity of Shallow Water Zoanthids (Cnidaria: Anthozoa: Hexacorallia) in Florida

inferredcites →https://doi.org/10.1155/2015/621815openalex-snapshot

A Case of Palytoxin Poisoning in a Home Aquarium Enthusiast and His Family

inferredcites →https://doi.org/10.1163/18759866-07904002openalex-snapshot

Zoanthids of the Cape Verde Islands and their symbionts: previously unexamined diversity in the Northeastern Atlantic

inferredcites →https://doi.org/10.1186/1476-4598-12-1openalex-snapshot

Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion

inferredcites →https://doi.org/10.1186/1476-4598-12-12openalex-snapshot

Head and neck cancer cells and xenografts are very sensitive to palytoxin: decrease of c-jun n-terminale kinase-3 expression enhances palytoxin toxicity

inferredcites →https://doi.org/10.1227/01.neu.0000311080.43024.0eopenalex-snapshot

TARGETING THE α 1 SUBUNIT OF THE SODIUM PUMP TO COMBAT GLIOBLASTOMA CELLS

inferredcites →https://doi.org/10.1242/jeb.02309openalex-snapshot

Nitric oxide and cnidarian bleaching: an eviction notice mediates breakdown of a symbiosis

inferredcites →https://doi.org/10.1271/bbb.65.2585openalex-snapshot

Structure Elucidation of Ostreocin D, a Palytoxin Analog Isolated from the Dinoflagellate Ostreopsis siamensis

inferredcites →https://doi.org/10.1271/bbb.68.955openalex-snapshot

Zooxanthellamide B, a Novel Large Polyhydroxy Metabolite from a Marine Dinoflagellate ofSymbiodiniumsp.

inferredcites →https://doi.org/10.1371/journal.pone.0016163openalex-snapshot

E2F1 Regulates Cellular Growth by mTORC1 Signaling

inferredcites →https://doi.org/10.1371/journal.pone.0018235openalex-snapshot

Palytoxin Found in Palythoa sp. Zoanthids (Anthozoa, Hexacorallia) Sold in the Home Aquarium Trade

inferredcites →https://doi.org/10.1593/neo.05850openalex-snapshot

Cardenolide-Induced Lysosomal Membrane Permeabilization Demonstrates Therapeutic Benefits in Experimental Human Non-Small Cell Lung Cancers

inferredcites →https://doi.org/10.2108/zsj.21.517openalex-snapshot

Reconsidering Zoanthus spp. Diversity: Molecular Evidence of Conspecifity Within Four Previously Presumed Species

inferredcites →https://doi.org/10.23860/diss-1950openalex-snapshot

Isolation of marine metabolites from Symbiodinium species of dinoflagellates

inferredcites →https://doi.org/10.3354/meps195029openalex-snapshot

Separation of chlorophylls and carotenoids from marine phytoplankton:a new HPLC method using a reversed phase C8 column and pyridine-containing mobile phases

inferredcites →https://doi.org/10.3390/md11030584openalex-snapshot

Characterization of Palytoxin Binding to HaCaT Cells Using a Monoclonal Anti-Palytoxin Antibody

inferredcites →https://doi.org/10.3390/md9040543openalex-snapshot

First Evidence of Palytoxin and 42-Hydroxy-palytoxin in the Marine Cyanobacterium Trichodesmium

inferredcites →https://doi.org/10.4415/ann_12_04_08openalex-snapshot

Sanitary problems related to the presence of Ostreopsis spp. in the Mediterranean Sea: a multidisciplinary scientific approach

inferredcites →https://doi.org/10.5134/175748openalex-snapshot

PURIFICATION OF THE TOXIN IN A ZOANTHID PALYTHOA TUBERCULOSA

inferredcites →https://doi.org/10.5487/tr.2016.32.3.177openalex-snapshot

Targeting Cancer Metabolism - Revisiting the Warburg Effects

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1002/aqc.3487openalex-snapshot

Effects of low pH and high temperature on two Palythoa spp. and predator–prey interactions in the subtropical eastern Atlantic

inferred← citeshttps://doi.org/10.1007/s12601-024-00175-wopenalex-snapshot

Enhanced Chromatographic Separation for Quantitative Accuracy of Palytoxin

inferred← citeshttps://doi.org/10.3390/md17040216openalex-snapshot

Soritesidine, a Novel Proteinous Toxin from the Okinawan Marine Sponge Spongosorites sp.

inferred← citeshttps://doi.org/10.3390/s21175784openalex-snapshot

Emerging Optical Materials in Sensing and Discovery of Bioactive Compounds

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