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The alkyl side chain of PACA nanoparticles dictates the impact on cellular stress responses and the mode of particle-induced cell death

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/adma.201704007openalex-snapshot

Emerging Strategies of Cancer Therapy Based on Ferroptosis

inferredcites →https://doi.org/10.1002/adma.201870084openalex-snapshot

Cancer Therapy: Emerging Strategies of Cancer Therapy Based on Ferroptosis (Adv. Mater. 12/2018)

inferredcites →https://doi.org/10.1002/anie.201800272openalex-snapshot

Hydrophilicity Regulates the Stealth Properties of Polyphosphoester‐Coated Nanocarriers

inferredcites →https://doi.org/10.1002/cmmi.1639openalex-snapshot

Nanoparticle‐stabilized microbubbles for multimodal imaging and drug delivery

inferredcites →https://doi.org/10.1002/ejlt.201100050openalex-snapshot

Lipids, curvature, and nano‐medicine

inferredcites →https://doi.org/10.1002/jbm.820140202openalex-snapshot

In vitro heterogeneous degradation of poly(n‐alkyl α‐cyanoacrylates)

inferredcites →https://doi.org/10.1002/jcb.240590805openalex-snapshot

N-Acetylcysteine (NAC) and glutathione (GSH): Antioxidant and chemopreventive properties, with special reference to lung cancer

inferredcites →https://doi.org/10.1002/jcp.21366openalex-snapshot

The x cystine/glutamate antiporter: A potential target for therapy of cancer and other diseases

inferredcites →https://doi.org/10.1006/abio.2000.4498openalex-snapshot

Determining Glutathione and Glutathione Disulfide Using the Fluorescence Probe o-Phthalaldehyde

inferredcites →https://doi.org/10.1006/bbrc.1997.6943openalex-snapshot

An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements

inferredcites →https://doi.org/10.1007/s00018-016-2309-8openalex-snapshot

PIKfyve inhibition increases exosome release and induces secretory autophagy

inferredcites →https://doi.org/10.1016/j.actbio.2018.02.036openalex-snapshot

Beyond the protein corona – lipids matter for biological response of nanocarriers

inferredcites →https://doi.org/10.1016/j.addr.2013.08.008openalex-snapshot

Drug delivery to the central nervous system by polymeric nanoparticles: What do we know?

inferredcites →https://doi.org/10.1016/j.bbamcr.2014.04.006openalex-snapshot

Keeping the eIF2 alpha kinase Gcn2 in check

inferredcites →https://doi.org/10.1016/j.bbamcr.2018.02.010openalex-snapshot

Nrf2-Keap1 signaling in oxidative and reductive stress

inferredcites →https://doi.org/10.1016/j.ccr.2013.08.020openalex-snapshot

Glutamine Sensitivity Analysis Identifies the xCT Antiporter as a Common Triple-Negative Breast Tumor Therapeutic Target

inferredcites →https://doi.org/10.1016/j.cell.2017.09.021openalex-snapshot

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

inferredcites →https://doi.org/10.1016/j.cmet.2017.07.001openalex-snapshot

The Dawn of the Age of Amino Acid Sensors for the mTORC1 Pathway

inferredcites →https://doi.org/10.1016/j.lfs.2017.08.003openalex-snapshot

A review of endoplasmic reticulum (ER) stress and nanoparticle (NP) exposure

inferredcites →https://doi.org/10.1016/j.smim.2017.10.001openalex-snapshot

Formation of the Protein Corona: The Interface between Nanoparticles and the Immune System

inferredcites →https://doi.org/10.1016/j.ultrasmedbio.2017.06.029openalex-snapshot

Ultrasound Improves the Delivery and Therapeutic Effect of Nanoparticle-Stabilized Microbubbles in Breast Cancer Xenografts

inferredcites →https://doi.org/10.1016/s0169-409x(03)00041-3openalex-snapshot

Poly(alkylcyanoacrylates) as biodegradable materials for biomedical applications

inferredcites →https://doi.org/10.1021/acscentsci.7b00028openalex-snapshot

On the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death

inferredcites →https://doi.org/10.1038/bcj.2016.56openalex-snapshot

Intracellular glutathione determines bortezomib cytotoxicity in multiple myeloma cells

inferredcites →https://doi.org/10.1038/nature23007openalex-snapshot

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

inferredcites →https://doi.org/10.1038/nature24297openalex-snapshot

Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

inferredcites →https://doi.org/10.1038/nmat2442openalex-snapshot

Understanding biophysicochemical interactions at the nano–bio interface

inferredcites →https://doi.org/10.1038/nnano.2016.164openalex-snapshot

Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth

inferredcites →https://doi.org/10.1038/nrd.2015.6openalex-snapshot

Regulated necrosis: disease relevance and therapeutic opportunities

inferredcites →https://doi.org/10.1038/nrm3270openalex-snapshot

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

inferredcites →https://doi.org/10.1038/s41419-017-0057-9openalex-snapshot

Immunological consequences of kidney cell death

inferredcites →https://doi.org/10.1038/s41598-018-19213-4openalex-snapshot

The ferroptosis inducer erastin irreversibly inhibits system xc− and synergizes with cisplatin to increase cisplatin’s cytotoxicity in cancer cells

inferredcites →https://doi.org/10.1038/sj.bjc.6604485openalex-snapshot

The xc− cystine/glutamate antiporter: a mediator of pancreatic cancer growth with a role in drug resistance

inferredcites →https://doi.org/10.1038/srep30033openalex-snapshot

Crosstalk between cystine and glutathione is critical for the regulation of amino acid signaling pathways and ferroptosis

inferredcites →https://doi.org/10.1038/srep32886openalex-snapshot

Integrated stress response of vertebrates is regulated by four eIF2α kinases

inferredcites →https://doi.org/10.1073/pnas.012485299openalex-snapshot

Regulation of starvation- and virus-induced autophagy by the eIF2α kinase signaling pathway

inferredcites →https://doi.org/10.1073/pnas.87.7.2466openalex-snapshot

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.

inferredcites →https://doi.org/10.1080/10937404.2017.1305924openalex-snapshot

Engineered nanomaterial-induced lysosomal membrane permeabilization and anti-cathepsin agents

inferredcites →https://doi.org/10.1080/15548627.2015.1063871openalex-snapshot

Sensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay

inferredcites →https://doi.org/10.1091/mbc.e05-03-0268openalex-snapshot

PERK and GCN2 Contribute to eIF2α Phosphorylation and Cell Cycle Arrest after Activation of the Unfolded Protein Response Pathway

inferredcites →https://doi.org/10.1111/febs.13598openalex-snapshot

Cell death induced by endoplasmic reticulum stress

inferredcites →https://doi.org/10.1111/j.1530-0277.2005.00061.xopenalex-snapshot

Structural Constraints for Alcohol‐Stimulated Ca2+Release in Neural Crest, and Dual Agonist/Antagonist Properties ofn‐Octanol

inferredcites →https://doi.org/10.1111/jcmm.13008openalex-snapshot

Ferroptosis, a new form of cell death, and its relationships with tumourous diseases

inferredcites →https://doi.org/10.1146/annurev-biochem-061516-045037openalex-snapshot

Oxidative Stress

inferredcites →https://doi.org/10.1155/2014/686984openalex-snapshot

mTOR Signaling in Protein Translation Regulation: Implications in Cancer Genesis and Therapeutic Interventions

inferredcites →https://doi.org/10.1159/000100812openalex-snapshot

Sulfasalazine-Induced Reduction of Glutathione Levels in Breast Cancer Cells: Enhancement of Growth-Inhibitory Activity of Doxorubicin

inferredcites →https://doi.org/10.1161/atvbaha.110.204354openalex-snapshot

Oxidized Phospholipids Regulate Expression of ATF4 and VEGF in Endothelial Cells via NRF2-Dependent Mechanism: Novel Point of Convergence Between Electrophilic and Unfolded Protein Stress Pathways

inferredcites →https://doi.org/10.1167/iovs.10-5775openalex-snapshot

Transcriptional Regulation of Activating Transcription Factor 4 under Oxidative Stress in Retinal Pigment Epithelial ARPE-19/HPV-16 Cells

inferredcites →https://doi.org/10.1186/s11671-018-2457-xopenalex-snapshot

Dependence of Nanoparticle Toxicity on Their Physical and Chemical Properties

inferredcites →https://doi.org/10.1186/s12951-015-0156-7openalex-snapshot

Cellular uptake and intracellular degradation of poly(alkyl cyanoacrylate) nanoparticles

inferredcites →https://doi.org/10.1248/bpb.b16-00854openalex-snapshot

Nano-safety Research: Examining the Associations among the Biological Effects of Nanoparticles and Their Physicochemical Properties and Kinetics

inferredcites →https://doi.org/10.15252/embr.201642195openalex-snapshot

The integrated stress response

inferredcites →https://doi.org/10.3389/fimmu.2017.01719openalex-snapshot

Amino Acid Sensing via General Control Nonderepressible-2 Kinase and Immunological Programming

inferredcites →https://doi.org/10.3389/fphar.2017.00992openalex-snapshot

The Role of Ferroptosis in Cancer Development and Treatment Response

inferredcites →https://doi.org/10.3390/ijms18010120openalex-snapshot

The Role of Reactive Oxygen Species (ROS) in the Biological Activities of Metallic Nanoparticles

inferredcites →https://doi.org/10.3390/ijms18112454openalex-snapshot

Cytotoxicity of Poly(Alkyl Cyanoacrylate) Nanoparticles

inferredcites →https://doi.org/10.7554/elife.00498openalex-snapshot

Pharmacological brake-release of mRNA translation enhances cognitive memory

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.3390/app11094305openalex-snapshot

Surface Functionalization of PLGA Nanoparticles to Increase Transport across the BBB for Alzheimer’s Disease

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