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Identification of novel and structurally diverse N-Methyl-D-Aspartate Receptor Antagonists: Successful Application of Pharmacophore Modeling, Virtual Screening and Molecular Docking
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Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1016/j.bbadis.2012.11.013openalex-snapshot
Role of the N-methyl-d-aspartate receptors complex in amyotrophic lateral sclerosis
inferredcites →https://doi.org/10.1016/j.bmcl.2010.06.103openalex-snapshot
Discovery of novel α7 nicotinic receptor antagonists
inferredcites →https://doi.org/10.1016/j.coph.2005.09.007openalex-snapshot
Mechanism of action of memantine
inferredcites →https://doi.org/10.1016/j.phrs.2004.05.005openalex-snapshot
Dementia of Alzheimer’s disease and other neurodegenerative disorders—memantine, a new hope
inferredcites →https://doi.org/10.1016/j.phrs.2005.02.007openalex-snapshot
PARP-1 inhibition to treat cancer, ischemia, inflammation
inferredcites →https://doi.org/10.1016/s0028-3908(99)00019-2openalex-snapshot
Memantine is a clinically well tolerated N-methyl-d-aspartate (NMDA) receptor antagonist—a review of preclinical data
inferredcites →https://doi.org/10.1016/s1056-8719(00)00107-6openalex-snapshot
Drug-like properties and the causes of poor solubility and poor permeability
inferredcites →https://doi.org/10.1021/ci6004299openalex-snapshot
Validation Studies of the Site-Directed Docking Program LibDock
inferredcites →https://doi.org/10.1021/jm00018a018openalex-snapshot
Novel Benzo[b]quinolizinium Cations as Uncompetitive N-Methyl-D-aspartic Acid (NMDA) Antagonists: The Relationship between log D and Agonist Independent (Closed) NMDA Channel Block
inferredcites →https://doi.org/10.1021/jm00043a020openalex-snapshot
Triazolinone Biphenylsulfonamide Derivatives as Orally Active Angiotensin II Antagonists with Potent AT1 Receptor Affinity and Enhanced AT2 Affinity
inferredcites →https://doi.org/10.1021/jm050852fopenalex-snapshot
Discovery of a Novel Family of SARS-CoV Protease Inhibitors by Virtual Screening and 3D-QSAR Studies
inferredcites →https://doi.org/10.1038/aps.2009.24openalex-snapshot
Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative diseases
inferredcites →https://doi.org/10.1038/ncomms1295openalex-snapshot
Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors
inferredcites →https://doi.org/10.1039/c3mb00016hopenalex-snapshot
Discovery of Rho-kinase inhibitors by docking-based virtual screening
inferredcites →https://doi.org/10.1093/hmg/ddq160openalex-snapshot
Molecular mechanisms of neurodegeneration in Alzheimer's disease
inferredcites →https://doi.org/10.1101/cshperspect.a006189openalex-snapshot
Neuropathological Alterations in Alzheimer Disease
inferredcites →https://doi.org/10.1111/j.1476-5381.2012.02057.xopenalex-snapshot
Alzheimer's disease, β‐amyloid, glutamate, NMDA receptors and memantine – searching for the connections
inferredcites →https://doi.org/10.1124/mol.106.030700openalex-snapshot
Subunit-Specific Roles of Glycine-Binding Domains in Activation of NR1/NR3 N-Methyl-d-aspartate Receptors
inferredcites →https://doi.org/10.1186/2191-2858-2-7openalex-snapshot
In silico identification of novel lead compounds with AT1 receptor antagonist activity: successful application of chemical database screening protocol
inferredcites →https://doi.org/10.2174/157340911795677602openalex-snapshot
Molecular Docking: A Powerful Approach for Structure-Based Drug Discovery
inferredcites →https://doi.org/10.3390/ijms12129236openalex-snapshot
3D QSAR Pharmacophore Modeling, in Silico Screening, and Density Functional Theory (DFT) Approaches for Identification of Human Chymase Inhibitors
What points at this work
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inferred← citeshttps://doi.org/10.1093/biomethods/bpaa013openalex-snapshot
Pharmacophore-driven identification of N-methyl-D-receptor antagonists as potent neuroprotective agents validated using in vivo studies
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