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An insulin, AMPK, and steroid hormone-mediated metabolic switch regulates the transition between growth and diapause in C. elegans
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1 of the 72 references listed on this page is in the Retraction Watch database as retracted (export 2026-11-04): 10.1038/nature04533 (notice 2024-06-24).
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/(sici)1097-010x(19960201)274:2<93::aid-jez2>3.0.co;2-8openalex-snapshot
Rate of aerobic metabolism and superoxide production rate potential in the nematode Caenorhabditis elegans
inferredcites →https://doi.org/10.1002/cne.902190407openalex-snapshot
Developmental alterations in sensory neuroanatomy of the Caenorhabditis elegans dauer larva
inferredcites →https://doi.org/10.1002/jbio.201000120openalex-snapshot
Fast and long term lipid droplet tracking with CARS microscopy
inferredcites →https://doi.org/10.1007/s00425-015-2300-xopenalex-snapshot
The C. elegans dauer larva as a paradigm to study metabolic suppression and desiccation tolerance
inferredcites →https://doi.org/10.1016/0012-1606(88)90138-8openalex-snapshot
Mutants of Caenorhabditis elegans that form dauer-like larvae
inferredcites →https://doi.org/10.1016/0012-1606(89)90214-5openalex-snapshot
Developmental regulation of energy metabolism in Caenorhabditis elegans
inferredcites →https://doi.org/10.1016/b978-0-12-396968-2.00007-5openalex-snapshot
Steroid Regulation of C. elegans Diapause, Developmental Timing, and Longevity
inferredcites →https://doi.org/10.1016/j.bbapap.2008.05.017openalex-snapshot
Mass spectrometric proteome analysis suggests anaerobic shift in metabolism of Dauer larvae of Caenorhabditis elegans
inferredcites →https://doi.org/10.1016/j.cell.2006.01.037openalex-snapshot
Identification of Ligands for DAF-12 that Govern Dauer Formation and Reproduction in C. elegans
inferredcites →https://doi.org/10.1016/j.cell.2014.06.024openalex-snapshot
Ecdysone and Mediator Change Energy Metabolism to Terminate Proliferation in Drosophila Neural Stem Cells
inferredcites →https://doi.org/10.1016/j.cell.2015.02.004openalex-snapshot
Neuronal CRTC-1 Governs Systemic Mitochondrial Metabolism and Lifespan via a Catecholamine Signal
inferredcites →https://doi.org/10.1016/j.cels.2016.04.012openalex-snapshot
A Caenorhabditis elegans Genome-Scale Metabolic Network Model
inferredcites →https://doi.org/10.1016/j.cmet.2012.02.013openalex-snapshot
Impaired Insulin/IGF1 Signaling Extends Life Span by Promoting Mitochondrial L-Proline Catabolism to Induce a Transient ROS Signal
inferredcites →https://doi.org/10.1016/j.cmet.2012.07.016openalex-snapshot
Increased Levels of Hydrogen Peroxide Induce a HIF-1-dependent Modification of Lipid Metabolism in AMPK Compromised C. elegans Dauer Larvae
inferredcites →https://doi.org/10.1016/j.cmet.2017.09.024openalex-snapshot
Dietary Restriction and AMPK Increase Lifespan via Mitochondrial Network and Peroxisome Remodeling
inferredcites →https://doi.org/10.1016/j.cub.2008.07.097openalex-snapshot
The Target of Rapamycin Pathway Antagonizes pha-4/FoxA to Control Development and Aging
inferredcites →https://doi.org/10.1016/j.cub.2018.06.035openalex-snapshot
C. elegans Eats Its Own Intestine to Make Yolk Leading to Multiple Senescent Pathologies
inferredcites →https://doi.org/10.1016/j.devcel.2009.04.012openalex-snapshot
Methylation of the Sterol Nucleus by STRM-1 Regulates Dauer Larva Formation in Caenorhabditis elegans
inferredcites →https://doi.org/10.1016/j.exger.2005.09.006openalex-snapshot
Alternate metabolism during the dauer stage of the nematode Caenorhabditis elegans
inferredcites →https://doi.org/10.1016/j.mad.2006.01.006openalex-snapshot
Diapause-associated metabolic traits reiterated in long-lived daf-2 mutants in the nematode Caenorhabditis elegans
inferredcites →https://doi.org/10.1016/s0040-6031(96)03125-5openalex-snapshot
Heat flux and the calorimetric-respirometric ratio as measures of catabolic flux in mammalian cells
inferredcites →https://doi.org/10.1016/s0047-6374(03)00132-5openalex-snapshot
SAGE surveys C. elegans carbohydrate metabolism: evidence for an anaerobic shift in the long-lived dauer larva
inferredcites →https://doi.org/10.1016/s0531-5565(02)00063-3openalex-snapshot
Ageing is reversed, and metabolism is reset to young levels in recovering dauer larvae of C. elegans
inferredcites →https://doi.org/10.1016/s0960-9822(01)00594-2openalex-snapshot
daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans
inferredcites →https://doi.org/10.1016/s0960-9822(01)00595-4openalex-snapshot
Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway
inferredcites →https://doi.org/10.1021/pr401081bopenalex-snapshot
LC–MS Proteomics Analysis of the Insulin/IGF-1-Deficient Caenorhabditis elegans daf-2(e1370) Mutant Reveals Extensive Restructuring of Intermediary Metabolism
inferredcites →https://doi.org/10.1038/366461a0openalex-snapshot
A C. elegans mutant that lives twice as long as wild type
inferredcites →https://doi.org/10.1038/88850openalex-snapshot
Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
inferredcites →https://doi.org/10.1038/nature01789openalex-snapshot
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
inferredcites →https://doi.org/10.1038/nature04533openalex-snapshot
RETRACTED ARTICLE: A specific amyloid-β protein assembly in the brain impairs memory
inferredcites →https://doi.org/10.1038/nature07536openalex-snapshot
Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival
inferredcites →https://doi.org/10.1038/nchembio.2356openalex-snapshot
Small-molecule pheromones and hormones controlling nematode development
inferredcites →https://doi.org/10.1038/ncomms9060openalex-snapshot
Integration of carbohydrate metabolism and redox state controls dauer larva formation in Caenorhabditis elegans
inferredcites →https://doi.org/10.1038/nrm3772openalex-snapshot
Metabolic requirements for the maintenance of self-renewing stem cells
inferredcites →https://doi.org/10.1038/s41598-018-24925-8openalex-snapshot
Endocannabinoids in Caenorhabditis elegans are essential for the mobilization of cholesterol from internal reserves
inferredcites →https://doi.org/10.1039/b815064hopenalex-snapshot
Stereoselective synthesis of the hormonally active (25S)-Δ7-dafachronic acid, (25S)-Δ4-dafachronic acid, (25S)-dafachronic acid, and (25S)-cholestenoic acid
inferredcites →https://doi.org/10.1039/b817358copenalex-snapshot
Synthesis and biological activity of the (25R)-cholesten-26-oic acids—ligands for the hormonal receptor DAF-12 in Caenorhabditis elegans
inferredcites →https://doi.org/10.1039/c2ob25394aopenalex-snapshot
Stereoselective synthesis and hormonal activity of novel dafachronic acids and naturally occurring steroids isolated from corals
inferredcites →https://doi.org/10.1042/bst20120352openalex-snapshot
Parallels between embryo and cancer cell metabolism
inferredcites →https://doi.org/10.1051/medsci/20031967725openalex-snapshot
C. elegans : des neurones et des gènes
inferredcites →https://doi.org/10.1073/pnas.1714178115openalex-snapshot
Metabolic shift from glycogen to trehalose promotes lifespan and healthspan in Caenorhabditis elegans
inferredcites →https://doi.org/10.1074/mcp.o117.067082openalex-snapshot
MS Western, a Method of Multiplexed Absolute Protein Quantification is a Practical Alternative to Western Blotting
inferredcites →https://doi.org/10.1091/mbc.e05-01-0060openalex-snapshot
Genetic Analysis of Lysosomal Trafficking in Caenorhabditis elegans
inferredcites →https://doi.org/10.1093/genetics/150.1.129openalex-snapshot
Two Pleiotropic Classes of daf-2 Mutation Affect Larval Arrest, Adult Behavior, Reproduction and Longevity in Caenorhabditis elegans
inferredcites →https://doi.org/10.1093/genetics/77.1.71openalex-snapshot
THE GENETICS OF CAENORHABDITIS ELEGANS
inferredcites →https://doi.org/10.1101/087969532.33.739openalex-snapshot
Genetic and Environmental Regulation of Dauer Larva Development
inferredcites →https://doi.org/10.1101/gad.1255404openalex-snapshot
The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans
inferredcites →https://doi.org/10.1101/gad.14.12.1512openalex-snapshot
daf-12encodes a nuclear receptor that regulates the dauer diapause and developmental age inC. elegans
inferredcites →https://doi.org/10.1101/gad.1701508openalex-snapshot
C. elegans dauer formation and the molecular basis of plasticity
inferredcites →https://doi.org/10.1101/sqb.2012.76.010470openalex-snapshot
Nuclear Receptors and AMPK: Resetting Metabolism
inferredcites →https://doi.org/10.1111/acel.12273openalex-snapshot
Dietary restriction involves NAD +‐dependent mechanisms and a shift toward oxidative metabolism
inferredcites →https://doi.org/10.1111/j.1474-9726.2006.00203.xopenalex-snapshot
The nuclear hormone receptor DAF‐12 has opposing effects on Caenorhabditis elegans lifespan and regulates genes repressed in multiple long‐lived worms
inferredcites →https://doi.org/10.1126/science.1228967openalex-snapshot
A Steroid Receptor–MicroRNA Switch Regulates Life Span in Response to Signals from the Gonad
inferredcites →https://doi.org/10.1139/o59-099openalex-snapshot
A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION
inferredcites →https://doi.org/10.1152/ajpregu.00250.2015openalex-snapshot
Mechanisms of animal diapause: recent developments from nematodes, crustaceans, insects, and fish
inferredcites →https://doi.org/10.1186/1741-7007-8-14openalex-snapshot
A metabolic signature of long life in Caenorhabditis elegans
inferredcites →https://doi.org/10.1242/dev.00363openalex-snapshot
Global analysis of dauer gene expression inCaenorhabditis elegans
inferredcites →https://doi.org/10.1242/dev.02232openalex-snapshot
Inhibition of germline proliferation during C. elegans dauer development requires PTEN, LKB1 and AMPK signalling
inferredcites →https://doi.org/10.1242/dev.125.7.1191openalex-snapshot
daf-12 regulates developmental age and the dauer alternative in Caenorhabditis elegans
inferredcites →https://doi.org/10.1371/journal.pbio.0020280openalex-snapshot
Sterol-Derived Hormone(s) Controls Entry into Diapause in Caenorhabditis elegans by Consecutive Activation of DAF-12 and DAF-16
inferredcites →https://doi.org/10.1371/journal.pgen.1004109openalex-snapshot
DAF-16/FoxO Directly Regulates an Atypical AMP-Activated Protein Kinase Gamma Isoform to Mediate the Effects of Insulin/IGF-1 Signaling on Aging in Caenorhabditis elegans
inferredcites →https://doi.org/10.1371/journal.pgen.1004394openalex-snapshot
Loss of a Neural AMP-Activated Kinase Mimics the Effects of Elevated Serotonin on Fat, Movement, and Hormonal Secretions
inferredcites →https://doi.org/10.1371/journal.pgen.1005520openalex-snapshot
FLCN and AMPK Confer Resistance to Hyperosmotic Stress via Remodeling of Glycogen Stores
inferredcites →https://doi.org/10.1371/journal.pone.0032590openalex-snapshot
Gene Expression of the Tumour Suppressor LKB1 Is Mediated by Sp1, NF-Y and FOXO Transcription Factors
inferredcites →https://doi.org/10.1371/journal.pone.0130480openalex-snapshot
AMP-Activated Kinase Regulates Lipid Droplet Localization and Stability of Adipose Triglyceride Lipase in C. elegans Dauer Larvae
inferredcites →https://doi.org/10.1371/journal.pone.0148089openalex-snapshot
AMP-Activated Protein Kinase Regulates Oxidative Metabolism in Caenorhabditis elegans through the NHR-49 and MDT-15 Transcriptional Regulators
inferredcites →https://doi.org/10.1529/biophysj.104.047308openalex-snapshot
Interpreting Second-Harmonic Generation Images of Collagen I Fibrils
inferredcites →https://doi.org/10.1534/genetics.115.177998openalex-snapshot
Longevity Genes Revealed by Integrative Analysis of Isoform-Specific daf-16/FoxO Mutants of Caenorhabditis elegans
inferredcites →https://doi.org/10.7554/elife.13614openalex-snapshot
The glyoxylate shunt is essential for desiccation tolerance in C. elegans and budding yeast
inferredcites →https://doi.org/10.7554/elife.30057openalex-snapshot
daf-16/FoxO promotes gluconeogenesis and trehalose synthesis during starvation to support survival
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Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1021/acs.analchem.9b05670openalex-snapshot
Real-Time In-Organism NMR Metabolomics Reveals Different Roles of AMP-Activated Protein Kinase Catalytic Subunits
inferred← citeshttps://doi.org/10.1371/journal.pbio.3000309openalex-snapshot
AMPK regulates germline stem cell quiescence and integrity through an endogenous small RNA pathway
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