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Genome-wide associations reveal human-mouse genetic convergence and modifiers of myogenesis, CPNE1 and STC2

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Estimation of the multiple testing burden for genomewide association studies of nearly all common variants

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3D reconstruction of histological sections: Application to mammary gland tissue

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Molecular Cloning of a Second Human Stanniocalcin Homologue (STC2)

inferredcites →https://doi.org/10.1007/s00018-002-8522-7openalex-snapshot

Copines: a ubiquitous family of Ca2+-dependent phospholipid-binding proteins

inferredcites →https://doi.org/10.1007/s003350010218openalex-snapshot

Genetic architecture of adiposity in the cross of LG/J and SM/J inbred mice

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Suggestion of GLYAT gene underlying variation of bone size and body lean mass as revealed by a bivariate genome-wide association study

inferredcites →https://doi.org/10.1016/j.ajhg.2009.02.004openalex-snapshot

Genome-wide Association and Replication Studies Identified TRHR as an Important Gene for Lean Body Mass

inferredcites →https://doi.org/10.1016/j.ajhg.2015.11.020openalex-snapshot

Genotype Imputation with Millions of Reference Samples

inferredcites →https://doi.org/10.1016/j.ajhg.2016.08.016openalex-snapshot

REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants

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Basic histological structure and functions of facial skin

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Replicability and Prediction: Lessons and Challenges from GWAS

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Longitudinal changes in body composition associated with healthy ageing: men, aged 20–96 years

inferredcites →https://doi.org/10.1038/jhg.2011.125openalex-snapshot

Genome-wide association study of copy number variation identified gremlin1 as a candidate gene for lean body mass

inferredcites →https://doi.org/10.1038/nature04226openalex-snapshot

A haplotype map of the human genome

inferredcites →https://doi.org/10.1038/nature15393openalex-snapshot

A global reference for human genetic variation

inferredcites →https://doi.org/10.1038/ncomms5099openalex-snapshot

Adipocytes arise from multiple lineages that are heterogeneously and dynamically distributed

inferredcites →https://doi.org/10.1038/ng.2213openalex-snapshot

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

inferredcites →https://doi.org/10.1038/ng.2310openalex-snapshot

Genome-wide efficient mixed-model analysis for association studies

inferredcites →https://doi.org/10.1038/ng.2876openalex-snapshot

Advantages and pitfalls in the application of mixed-model association methods

inferredcites →https://doi.org/10.1038/ng.3097openalex-snapshot

Defining the role of common variation in the genomic and biological architecture of adult human height

inferredcites →https://doi.org/10.1038/ng.3190openalex-snapshot

Efficient Bayesian mixed-model analysis increases association power in large cohorts

inferredcites →https://doi.org/10.1038/ng.3211openalex-snapshot

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

inferredcites →https://doi.org/10.1038/ng.3431openalex-snapshot

Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis

inferredcites →https://doi.org/10.1038/ng.3595openalex-snapshot

Genome-wide association of multiple complex traits in outbred mice by ultra-low-coverage sequencing

inferredcites →https://doi.org/10.1038/ng.3609openalex-snapshot

Genome-wide association study of behavioral, physiological and gene expression traits in outbred CFW mice

inferredcites →https://doi.org/10.1038/ng1702openalex-snapshot

A unified mixed-model method for association mapping that accounts for multiple levels of relatedness

inferredcites →https://doi.org/10.1038/nmeth.2019openalex-snapshot

Fiji: an open-source platform for biological-image analysis

inferredcites →https://doi.org/10.1038/nmeth0410-248openalex-snapshot

A method and server for predicting damaging missense mutations

inferredcites →https://doi.org/10.1038/nprot.2009.97openalex-snapshot

Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt

inferredcites →https://doi.org/10.1038/nrg1960openalex-snapshot

Genetic relatedness analysis: modern data and new challenges

inferredcites →https://doi.org/10.1038/nrg2813openalex-snapshot

New approaches to population stratification in genome-wide association studies

inferredcites →https://doi.org/10.1038/nrg3821openalex-snapshot

Relatedness in the post-genomic era: is it still useful?

inferredcites →https://doi.org/10.1038/s41467-017-00031-7openalex-snapshot

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

inferredcites →https://doi.org/10.1038/s41467-017-01261-5openalex-snapshot

Functional mapping and annotation of genetic associations with FUMA

inferredcites →https://doi.org/10.1038/s41467-018-07642-8openalex-snapshot

Genome wide association analysis in a mouse advanced intercross line

inferredcites →https://doi.org/10.1038/s41586-018-0579-zopenalex-snapshot

The UK Biobank resource with deep phenotyping and genomic data

inferredcites →https://doi.org/10.1038/s41588-018-0144-6openalex-snapshot

Mixed-model association for biobank-scale datasets

inferredcites →https://doi.org/10.1038/s41588-018-0321-7openalex-snapshot

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

inferredcites →https://doi.org/10.1073/pnas.0337561100openalex-snapshot

Comparison of mouse and human genomes followed by experimental verification yields an estimated 1,019 additional genes

inferredcites →https://doi.org/10.1074/jbc.m114.611665openalex-snapshot

Stanniocalcin-2 Inhibits Mammalian Growth by Proteolytic Inhibition of the Insulin-like Growth Factor Axis

inferredcites →https://doi.org/10.1086/281181openalex-snapshot

Genetics of Body Size and Related Characters. I. Selecting Small and Large Races of the Laboratory Mouse

inferredcites →https://doi.org/10.1089/bio.2015.0032openalex-snapshot

A Novel Approach to High-Quality Postmortem Tissue Procurement: The GTEx Project

inferredcites →https://doi.org/10.1089/gtmb.2010.0036openalex-snapshot

Using SIFT and PolyPhen to Predict Loss-of-Function and Gain-of-Function Mutations

inferredcites →https://doi.org/10.1093/ajcn/76.2.378openalex-snapshot

Total-body skeletal muscle mass: estimation by a new dual-energy X-ray absorptiometry method

inferredcites →https://doi.org/10.1093/ajcn/nqy272openalex-snapshot

Disentangling the genetics of lean mass

inferredcites →https://doi.org/10.1093/bioinformatics/btg112openalex-snapshot

R/qtl: QTL mapping in experimental crosses

inferredcites →https://doi.org/10.1093/bioinformatics/bti525openalex-snapshot

BioMart and Bioconductor: a powerful link between biological databases and microarray data analysis

inferredcites →https://doi.org/10.1093/genetics/138.3.963openalex-snapshot

Empirical threshold values for quantitative trait mapping.

inferredcites →https://doi.org/10.1093/genetics/141.3.1199openalex-snapshot

Advanced intercross lines, an experimental population for fine genetic mapping.

inferredcites →https://doi.org/10.1093/genetics/142.4.1305openalex-snapshot

Quantitative Trait Loci for Murine Growth

inferredcites →https://doi.org/10.1093/genetics/151.1.373openalex-snapshot

Statistical Methods for Mapping Quantitative Trait Loci From a Dense Set of Markers

inferredcites →https://doi.org/10.1093/geronj/45.3.m82openalex-snapshot

The Role of Muscle Loss in the Age-Related Decline of Grip Strength: Cross-Sectional and Longitudinal Perspectives

inferredcites →https://doi.org/10.1093/hmg/ddy327openalex-snapshot

Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry

inferredcites →https://doi.org/10.1093/nar/29.9.e45openalex-snapshot

A new mathematical model for relative quantification in real-time RT-PCR

inferredcites →https://doi.org/10.1093/nar/gkg509openalex-snapshot

SIFT: predicting amino acid changes that affect protein function

inferredcites →https://doi.org/10.1093/nar/gkx1098openalex-snapshot

Ensembl 2018

inferredcites →https://doi.org/10.1093/nar/gky1016openalex-snapshot

CADD: predicting the deleteriousness of variants throughout the human genome

inferredcites →https://doi.org/10.1093/oxfordjournals.jhered.a104463openalex-snapshot

A STUDY OF THE INHERITANCE OF BODY WEIGHT IN THE ALBINO MOUSE BY SELECTION

inferredcites →https://doi.org/10.1111/acel.12228openalex-snapshot

Large‐scale analysis reveals a functional single‐nucleotide polymorphism in the 5′‐flanking region of PRDM 16 gene associated with lean body mass

inferredcites →https://doi.org/10.1111/j.1420-9101.2005.00917.xopenalex-snapshot

Combining probability from independent tests: the weighted Z ‐method is superior to Fisher's approach

inferredcites →https://doi.org/10.1111/j.1420-9101.2011.02297.xopenalex-snapshot

Optimally weighted Z-test is a powerful method for combining probabilities in meta-analysis

inferredcites →https://doi.org/10.1111/j.1440-1681.2007.04752.xopenalex-snapshot

AGE‐RELATED CHANGES IN THE STRUCTURE AND FUNCTION OF SKELETAL MUSCLES

inferredcites →https://doi.org/10.1111/j.1532-5415.2004.52014.xopenalex-snapshot

The Healthcare Costs of Sarcopenia in the United States

inferredcites →https://doi.org/10.1113/jp274148openalex-snapshot

Structure and function of human muscle fibres and muscle proteome in physically active older men

inferredcites →https://doi.org/10.1113/jphysiol.2013.264457openalex-snapshot

A cellular memory mechanism aids overload hypertrophy in muscle long after an episodic exposure to anabolic steroids

inferredcites →https://doi.org/10.1152/ajpendo.00268.2004openalex-snapshot

Human stanniocalcin-2 exhibits potent growth-suppressive properties in transgenic mice independently of growth hormone and IGFs

inferredcites →https://doi.org/10.1152/jappl.1999.86.1.188openalex-snapshot

Muscle quality. I. Age-associated differences between arm and leg muscle groups

inferredcites →https://doi.org/10.1152/jappl.2000.89.1.81openalex-snapshot

Skeletal muscle mass and distribution in 468 men and women aged 18–88 yr

inferredcites →https://doi.org/10.1152/japplphysiol.00246.2003openalex-snapshot

Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia

inferredcites →https://doi.org/10.1152/physiolgenomics.00055.2014openalex-snapshot

Discovery and refinement of muscle weight QTLs in B6 × D2 advanced intercross mice

inferredcites →https://doi.org/10.1152/physiolgenomics.00092.2016openalex-snapshot

Fine-mapping of genes determining extrafusal fiber properties in murine soleus muscle

inferredcites →https://doi.org/10.1152/physiolgenomics.00100.2010openalex-snapshot

Fine-mapping of muscle weight QTL in LG/J and SM/J intercrosses

inferredcites →https://doi.org/10.1186/1471-2164-13-592openalex-snapshot

Resolving candidate genes of mouse skeletal muscle QTL via RNA-Seq and expression network analyses

inferredcites →https://doi.org/10.1186/1471-2164-15-349openalex-snapshot

A network-based approach to identify substrate classes of bacterial glycosyltransferases

inferredcites →https://doi.org/10.1186/1471-2164-15-99openalex-snapshot

The effect of dietary fat intake on hepatic gene expression in LG/J AND SM/J mice

inferredcites →https://doi.org/10.1186/s12864-015-1592-3openalex-snapshot

Using whole-genome sequences of the LG/J and SM/J inbred mouse strains to prioritize quantitative trait genes and nucleotides

inferredcites →https://doi.org/10.1186/s13742-015-0047-8openalex-snapshot

Second-generation PLINK: rising to the challenge of larger and richer datasets

inferredcites →https://doi.org/10.1210/jc.2016-1219openalex-snapshot

Contribution of Heritability and Epigenetic Factors to Skeletal Muscle Mass Variation in United Kingdom Twins

inferredcites →https://doi.org/10.1210/jc.82.2.407openalex-snapshot

Testosterone Replacement Increases Fat-Free Mass and Muscle Size in Hypogonadal Men

inferredcites →https://doi.org/10.1214/09-sts307openalex-snapshot

Population Structure and Cryptic Relatedness in Genetic Association Studies

inferredcites →https://doi.org/10.1371/journal.pmed.1001779openalex-snapshot

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

inferredcites →https://doi.org/10.1371/journal.pone.0089776openalex-snapshot

Genome-Wide Association Study Identified Copy Number Variants Important for Appendicular Lean Mass

inferredcites →https://doi.org/10.14814/phy2.13561openalex-snapshot

Replication and discovery of musculoskeletal QTLs in LG/J and SM/J advanced intercross lines

inferredcites →https://doi.org/10.1507/endocrj.ej15-0154openalex-snapshot

Recent genetic discoveries in osteoporosis, sarcopenia and obesity [Review]

inferredcites →https://doi.org/10.1534/g3.111.001198openalex-snapshot

Genotype Imputation with Thousands of Genomes

inferredcites →https://doi.org/10.1534/g3.113.007948openalex-snapshot

Practical Considerations Regarding the Use of Genotype and Pedigree Data to Model Relatedness in the Context of Genome-Wide Association Studies

inferredcites →https://doi.org/10.1534/genetics.106.061549openalex-snapshot

Poor Performance of Bootstrap Confidence Intervals for the Location of a Quantitative Trait Locus

inferredcites →https://doi.org/10.1534/genetics.107.080101openalex-snapshot

Efficient Control of Population Structure in Model Organism Association Mapping

inferredcites →https://doi.org/10.1534/genetics.110.116863openalex-snapshot

Genome-Wide Association Studies and the Problem of Relatedness Among Advanced Intercross Lines and Other Highly Recombinant Populations

inferredcites →https://doi.org/10.1534/genetics.112.146332openalex-snapshot

A Simulation Study of Permutation, Bootstrap, and Gene Dropping for Assessing Statistical Significance in the Case of Unequal Relatedness

inferredcites →https://doi.org/10.1534/genetics.114.167056openalex-snapshot

High-Resolution Genetic Mapping of Complex Traits from a Combined Analysis of F2 and Advanced Intercross Mice

inferredcites →https://doi.org/10.1534/genetics.117.300360openalex-snapshot

Transformation of Summary Statistics from Linear Mixed Model Association on All-or-None Traits to Odds Ratio

inferredcites →https://doi.org/10.18632/oncotarget.12545openalex-snapshot

Charcot-Marie-Tooth gene, SBF2, associated with taxane-induced peripheral neuropathy in African Americans

inferredcites →https://doi.org/10.3389/fgene.2011.00099openalex-snapshot

QTL analysis of type I and Type IIA fibers in soleus muscle in a cross between LG/J and SM/J mouse strains

inferredcites →https://doi.org/10.5808/gi.2016.14.4.173openalex-snapshot

Comparison of Two Meta-Analysis Methods: Inverse-Variance-Weighted Average and Weighted Sum of Z-Scores

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1002/oby.22927openalex-snapshot

Genome‐Wide Association Study in 3,173 Outbred Rats Identifies Multiple Loci for Body Weight, Adiposity, and Fasting Glucose

inferred← citeshttps://doi.org/10.3390/genes11121459openalex-snapshot

The Association of Multiple Gene Variants with Ageing Skeletal Muscle Phenotypes in Elderly Women

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