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Quantifying the contribution of four resistance mechanisms to ciprofloxacin minimum inhibitory concentration in Escherichia coli : a systematic review
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/j.1875-9114.1988.tb04058.xopenalex-snapshot
Ciprofloxacin: Chemistry, Mechanism of Action, Resistance, Antimicrobial Spectrum, Pharmacokinetics, Clinical Trials, and Adverse Reactions
inferredcites →https://doi.org/10.1016/j.ijantimicag.2005.02.006openalex-snapshot
Mechanisms of quinolone resistance in Escherichia coli and Salmonella: Recent developments
inferredcites →https://doi.org/10.1016/j.ijantimicag.2011.04.013openalex-snapshot
Transferable plasmid-mediated quinolone resistance in association with extended-spectrum β-lactamases and fluoroquinolone-acetylating aminoglycoside-6′-N-acetyltransferase in clinical isolates of Vibrio fluvialis
inferredcites →https://doi.org/10.1016/j.ijantimicag.2012.07.019openalex-snapshot
Does mutation in gyrA and/or parC or efflux pump expression play the main role in fluoroquinolone resistance in Escherichia coli urinary tract infections?: A statistical analysis study
inferredcites →https://doi.org/10.1016/j.ijantimicag.2018.01.012openalex-snapshot
Chromosomal mutations that accompany qnr in clinical isolates of Escherichia coli
inferredcites →https://doi.org/10.1016/j.vetmic.2013.08.010openalex-snapshot
Assessing the molecular basis of transferable quinolone resistance in Escherichia coli and Salmonella spp. from food-producing animals and food products
inferredcites →https://doi.org/10.1016/j.vetmic.2014.10.011openalex-snapshot
In vitro selection of resistance to pradofloxacin and ciprofloxacin in canine uropathogenic Escherichia coli isolates
inferredcites →https://doi.org/10.1016/s0140-6736(97)07322-4openalex-snapshot
Quinolone resistance from a transferable plasmid
inferredcites →https://doi.org/10.1016/s0168-1605(02)00547-0openalex-snapshot
Characterization of an Escherichia coli O157:H7 marR mutant
inferredcites →https://doi.org/10.1016/s1369-5274(99)00008-9openalex-snapshot
Mechanism of fluoroquinolone action
inferredcites →https://doi.org/10.1038/embor.2009.99openalex-snapshot
The SOS response promotes qnrB quinolone‐resistance determinant expression
inferredcites →https://doi.org/10.1038/nature02241openalex-snapshot
SOS response promotes horizontal dissemination of antibiotic resistance genes
inferredcites →https://doi.org/10.1038/nm1347openalex-snapshot
Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferase
inferredcites →https://doi.org/10.1038/nrmicro2298openalex-snapshot
The population genetics of commensal Escherichia coli
inferredcites →https://doi.org/10.1051/vetres:2001124openalex-snapshot
Quinolone resistance in Escherichia coli
inferredcites →https://doi.org/10.1054/drup.1998.0068openalex-snapshot
Mechanisms of fluoroquinolone resistance
inferredcites →https://doi.org/10.1073/pnas.082092899openalex-snapshot
Mechanism of plasmid-mediated quinolone resistance
inferredcites →https://doi.org/10.1073/pnas.1419939112openalex-snapshot
AcrB drug-binding pocket substitution confers clinically relevant resistance and altered substrate specificity
inferredcites →https://doi.org/10.1073/pnas.92.25.11801openalex-snapshot
Topoisomerase IV is a target of quinolones in Escherichia coli.
inferredcites →https://doi.org/10.1074/jbc.273.28.17879openalex-snapshot
Topoisomerase IV Catalysis and the Mechanism of Quinolone Action
inferredcites →https://doi.org/10.1074/jbc.273.35.22615openalex-snapshot
The DNA Gyrase-Quinolone Complex
inferredcites →https://doi.org/10.1086/314056openalex-snapshot
Mechanisms of Action and Resistance of Older and Newer Fluoroquinolones
inferredcites →https://doi.org/10.1089/mdr.2008.0834openalex-snapshot
High Rates of Plasmid-Mediated Quinolone Resistance QnrB Variants Among Ciprofloxacin-Resistant Escherichia coli and Klebsiella pneumoniae from Urinary Tract Infections in Korea
inferredcites →https://doi.org/10.1089/mdr.2011.0086openalex-snapshot
Prevalence and Characterization of Plasmid-Mediated Quinolone Resistance Genes in Extended-Spectrum β-Lactamase–Producing Enterobacteriaceae Isolates in Mexico
inferredcites →https://doi.org/10.1089/mdr.2016.0004openalex-snapshot
High Prevalence of Plasmid-Mediated Quinolone Resistance Determinants in Escherichia coli and Klebsiella pneumoniae Isolates from Pediatric Patients in China
inferredcites →https://doi.org/10.1089/mdr.2016.0031openalex-snapshot
Characterization of Plasmid-Mediated Quinolone Resistance Determinants in High-Level Quinolone-Resistant Enterobacteriaceae Isolates from the Community: First Report of qnrD Gene in Algeria
inferredcites →https://doi.org/10.1093/femsec/fiv015openalex-snapshot
Genetic characterization of fluoroquinolone resistant Escherichia coli from urban streams and municipal and hospital effluents
inferredcites →https://doi.org/10.1093/jac/48.suppl_1.5openalex-snapshot
Determination of minimum inhibitory concentrations
inferredcites →https://doi.org/10.1093/jac/dkg157openalex-snapshot
Interaction of plasmid and host quinolone resistance
inferredcites →https://doi.org/10.1093/jac/dkg207openalex-snapshot
Mechanisms of quinolone action and microbial response
inferredcites →https://doi.org/10.1093/jac/dkm167openalex-snapshot
Substrate specificity of the OqxAB multidrug resistance pump in Escherichia coli and selected enteric bacteria
inferredcites →https://doi.org/10.1093/jac/dkn077openalex-snapshot
Low selection of topoisomerase mutants from strains of Escherichia coli harbouring plasmid-borne qnr genes
inferredcites →https://doi.org/10.1093/jac/dkn115openalex-snapshot
Qnr-like pentapeptide repeat proteins in Gram-positive bacteria
inferredcites →https://doi.org/10.1093/jac/dkq375openalex-snapshot
Antibacterial activity of finafloxacin under different pH conditions against isogenic strains of Escherichia coli expressing combinations of defined mechanisms of fluoroquinolone resistance
inferredcites →https://doi.org/10.1093/jac/dkr548openalex-snapshot
qnr, aac(6′)-Ib-cr and qepA genes in Escherichia coli and Klebsiella spp.: genetic environments and plasmid and chromosomal location
inferredcites →https://doi.org/10.1093/jac/dks224openalex-snapshot
Impact of low-level fluoroquinolone resistance genes qnrA1, qnrB19 and qnrS1 on ciprofloxacin treatment of isogenic Escherichia coli strains in a murine urinary tract infection model
inferredcites →https://doi.org/10.1093/jac/dks514openalex-snapshot
Chromosomal and plasmid-mediated fluoroquinolone resistance mechanisms among broad-spectrum-cephalosporin-resistant Escherichia coli isolates recovered from companion animals in the USA
inferredcites →https://doi.org/10.1093/jac/dku308openalex-snapshot
Interplay between plasmid-mediated and chromosomal-mediated fluoroquinolone resistance and bacterial fitness in Escherichia coli
inferredcites →https://doi.org/10.1093/jac/dkv105openalex-snapshot
A novel alanine to serine substitution mutation in SoxS induces overexpression of efflux pumps and contributes to multidrug resistance in clinical Escherichia coli isolates
inferredcites →https://doi.org/10.1093/jac/dkv144openalex-snapshot
Effect of the efflux pump QepA2 combined with chromosomally mediated mechanisms on quinolone resistance and bacterial fitness inEscherichia coli: Table 1.
inferredcites →https://doi.org/10.1093/jac/dkv233openalex-snapshot
A mechanism-based pharmacokinetic/pharmacodynamic model allows prediction of antibiotic killing from MIC values for WT and mutants
inferredcites →https://doi.org/10.1093/jac/dkw258openalex-snapshot
Impact of AAC(6′)-Ib-cr in combination with chromosomal-mediated mechanisms on clinical quinolone resistance in Escherichia coli
inferredcites →https://doi.org/10.1093/jac/dkw364openalex-snapshot
Ciprofloxacin selects for RNA polymerase mutations with pleiotropic antibiotic resistance effects
inferredcites →https://doi.org/10.1093/jac/dkw576openalex-snapshot
Impact of plasmid-borne oqxAB on the development of fluoroquinolone resistance and bacterial fitness in Escherichia coli
inferredcites →https://doi.org/10.1093/jac/dkx201openalex-snapshot
Quinolone-resistant gyrase mutants demonstrate decreased susceptibility to triclosan
inferredcites →https://doi.org/10.1093/jac/dkx270openalex-snapshot
Fitness cost constrains the spectrum of marR mutations in ciprofloxacin-resistant Escherichia coli
inferredcites →https://doi.org/10.1093/jac/dkx375openalex-snapshot
Increased expression of Qnr is sufficient to confer clinical resistance to ciprofloxacin in Escherichia coli
inferredcites →https://doi.org/10.1093/molbev/msx052openalex-snapshot
Mutation supply and relative fitness shape the genotypes of ciprofloxacin-resistant Escherichia coli
inferredcites →https://doi.org/10.1093/nar/gku1003openalex-snapshot
STRING v10: protein–protein interaction networks, integrated over the tree of life
inferredcites →https://doi.org/10.1093/nar/gkx1138openalex-snapshot
FunCoup 4: new species, data, and visualization
inferredcites →https://doi.org/10.1111/j.1469-0691.2006.01389.xopenalex-snapshot
Correlation of quinolone resistance levels and differences in basal and quinolone-induced expression from three qnrA-containing plasmids
inferredcites →https://doi.org/10.1111/j.1574-6976.2007.00082.xopenalex-snapshot
Aeons of distress: an evolutionary perspective on the bacterial SOS response
inferredcites →https://doi.org/10.1126/science.6243420openalex-snapshot
DNA Gyrase and the Supercoiling of DNA
inferredcites →https://doi.org/10.1128/aac.00132-08openalex-snapshot
SOS Regulation of qnrB Expression
inferredcites →https://doi.org/10.1128/aac.00139-10openalex-snapshot
Prevalence and Dissemination of oqxAB in Escherichia coli Isolates from Animals, Farmworkers, and the Environment
inferredcites →https://doi.org/10.1128/aac.00143-07openalex-snapshot
Transferable Resistance to Aminoglycosides by Methylation of G1405 in 16S rRNA and to Hydrophilic Fluoroquinolones by QepA-Mediated Efflux in Escherichia coli
inferredcites →https://doi.org/10.1128/aac.00239-09openalex-snapshot
First Report of Plasmid-Mediated Quinolone Resistance Determinant qnrS1 in an Escherichia coli Strain of Animal Origin in Italy
inferredcites →https://doi.org/10.1128/aac.00339-07openalex-snapshot
New Plasmid-Mediated Fluoroquinolone Efflux Pump, QepA, Found in an Escherichia coli Clinical Isolate
inferredcites →https://doi.org/10.1128/aac.00378-06openalex-snapshot
Mobilizable IncQ-Related Plasmid Carrying a New Quinolone Resistance Gene, qnrS2 , Isolated from the Bacterial Community of a Wastewater Treatment Plant
inferredcites →https://doi.org/10.1128/aac.00616-07openalex-snapshot
Prevalence and Expression of the Plasmid-Mediated Quinolone Resistance Determinant qnrA1
inferredcites →https://doi.org/10.1128/aac.00927-10openalex-snapshot
In Vitro Effect of qnrA1 , qnrB1 , and qnrS1 Genes on Fluoroquinolone Activity against Isogenic Escherichia coli Isolates with Mutations in gyrA and parC
inferredcites →https://doi.org/10.1128/aac.00996-10openalex-snapshot
Expression of Multidrug Efflux Pump Genes acrAB-tolC , mdfA , and norE in Escherichia coli Clinical Isolates as a Function of Fluoroquinolone and Multidrug Resistance
inferredcites →https://doi.org/10.1128/aac.00997-08openalex-snapshot
qnrD , a Novel Gene Conferring Transferable Quinolone Resistance in Salmonella enterica Serovar Kentucky and Bovismorbificans Strains of Human Origin
inferredcites →https://doi.org/10.1128/aac.01137-07openalex-snapshot
Plasmid-Mediated qepA Gene among Escherichia coli Clinical Isolates from Japan
inferredcites →https://doi.org/10.1128/aac.01235-17openalex-snapshot
Reduced Chlorhexidine and Daptomycin Susceptibility in Vancomycin-Resistant Enterococcus faecium after Serial Chlorhexidine Exposure
inferredcites →https://doi.org/10.1128/aac.01400-08openalex-snapshot
New Plasmid-Mediated Quinolone Resistance Gene, qnrC , Found in a Clinical Isolate of Proteus mirabilis
inferredcites →https://doi.org/10.1128/aac.01664-08openalex-snapshot
Impact of Low-Level Resistance to Fluoroquinolones Due to qnrA1 and qnrS1 Genes or a gyrA Mutation on Ciprofloxacin Bactericidal Activity in a Murine Model of Escherichia coli Urinary Tract Infection
inferredcites →https://doi.org/10.1128/aac.02555-16openalex-snapshot
qnrE1 , a Member of a New Family of Plasmid-Located Quinolone Resistance Genes, Originated from the Chromosome of Enterobacter Species
inferredcites →https://doi.org/10.1128/aac.02615-16openalex-snapshot
Plasmidic qnr Genes Confer Clinical Resistance to Ciprofloxacin under Urinary Tract Physiological Conditions
inferredcites →https://doi.org/10.1128/aac.05142-11openalex-snapshot
Quinolone Induction of qnrVS1 in Vibrio splendidus and Plasmid-Carried qnrS1 in Escherichia coli, a Mechanism Independent of the SOS System
inferredcites →https://doi.org/10.1128/aac.33.6.886openalex-snapshot
Cloning and characterization of a DNA gyrase A gene from Escherichia coli that confers clinical resistance to 4-quinolones
inferredcites →https://doi.org/10.1128/aac.35.10.2031openalex-snapshot
Use of a broad-host-range gyrA plasmid for genetic characterization of fluoroquinolone-resistant gram-negative bacteria
inferredcites →https://doi.org/10.1128/aac.35.8.1647openalex-snapshot
Quinolone resistance-determining region in the DNA gyrase gyrB gene of Escherichia coli
inferredcites →https://doi.org/10.1128/aac.37.4.696openalex-snapshot
Mutations in the gyrA gene of a highly fluoroquinolone-resistant clinical isolate of Escherichia coli
inferredcites →https://doi.org/10.1128/aac.37.6.1247openalex-snapshot
Novel gyrA point mutation in a strain of Escherichia coli resistant to fluoroquinolones but not to nalidixic acid
inferredcites →https://doi.org/10.1128/aac.38.6.1284openalex-snapshot
Characterization of fluoroquinolone-resistant mutants of escherichia coli selected in vitro
inferredcites →https://doi.org/10.1128/aac.40.4.879openalex-snapshot
Genetic evidence for a role of parC mutations in development of high-level fluoroquinolone resistance in Escherichia coli
inferredcites →https://doi.org/10.1128/aac.41.1.175openalex-snapshot
Quinolone resistance locus nfxD of Escherichia coli is a mutant allele of the parE gene encoding a subunit of topoisomerase IV
inferredcites →https://doi.org/10.1128/aac.41.1.85openalex-snapshot
A novel, double mutation in DNA gyrase A of Escherichia coli conferring resistance to quinolone antibiotics
inferredcites →https://doi.org/10.1128/aac.42.10.2661openalex-snapshot
gyrA Mutations Associated with Fluoroquinolone Resistance in Eight Species of Enterobacteriaceae
inferredcites →https://doi.org/10.1128/aac.44.1.10-13.2000openalex-snapshot
Ineffectiveness of Topoisomerase Mutations in Mediating Clinically Significant Fluoroquinolone Resistance in Escherichia coli in the Absence of the AcrAB Efflux Pump
inferredcites →https://doi.org/10.1128/aac.44.7.1865-1868.2000openalex-snapshot
In Vivo Increase in Resistance to Ciprofloxacin in Escherichia coli Associated with Deletion of the C-Terminal Part of MarR
inferredcites →https://doi.org/10.1128/aac.45.4.1126-1136.2001openalex-snapshot
Antibiotic Susceptibility Profiles of Escherichia coli Strains Lacking Multidrug Efflux Pump Genes
inferredcites →https://doi.org/10.1128/aac.47.7.2242-2248.2003openalex-snapshot
Plasmid-Mediated Quinolone Resistance in Clinical Isolates of Escherichia coli from Shanghai, China
inferredcites →https://doi.org/10.1128/aac.49.10.4390-4392.2005openalex-snapshot
Contribution of Mutation at Amino Acid 45 of AcrR to acrB Expression and Ciprofloxacin Resistance in Clinical and Veterinary Escherichia coli Isolates
inferredcites →https://doi.org/10.1128/aac.49.2.801-803.2005openalex-snapshot
Cloning of a Novel Gene for Quinolone Resistance from a Transferable Plasmid in Shigella flexneri 2b
inferredcites →https://doi.org/10.1128/aac.49.7.3050-3052.2005openalex-snapshot
Interaction of the Plasmid-Encoded Quinolone Resistance Protein QnrA with Escherichia coli Topoisomerase IV
inferredcites →https://doi.org/10.1128/aac.50.4.1178-1182.2006openalex-snapshot
qnrB , Another Plasmid-Mediated Gene for Quinolone Resistance
inferredcites →https://doi.org/10.1128/cmr.00016-09openalex-snapshot
Plasmid-Mediated Quinolone Resistance: a Multifaceted Threat
inferredcites →https://doi.org/10.1128/mbio.00971-17openalex-snapshot
Quinolone Resistance Reversion by Targeting the SOS Response
inferredcites →https://doi.org/10.1128/mmbr.48.1.60-93.1984openalex-snapshot
Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli
inferredcites →https://doi.org/10.1136/bmj.b2535openalex-snapshot
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement
inferredcites →https://doi.org/10.1146/annurev-micro-090816-093813openalex-snapshot
Evolutionary Trajectories to Antibiotic Resistance
inferredcites →https://doi.org/10.1371/journal.pbio.1000096openalex-snapshot
Global Functional Atlas of Escherichia coli Encompassing Previously Uncharacterized Proteins
inferredcites →https://doi.org/10.1371/journal.pmed.1000097openalex-snapshot
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
inferredcites →https://doi.org/10.1371/journal.pone.0077968openalex-snapshot
Characterization of Plasmid-Mediated Quinolone Resistance (PMQR) Genes in Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae Pediatric Clinical Isolates in Mexico
inferredcites →https://doi.org/10.1371/journal.pone.0178888openalex-snapshot
Genomic and phenotypic characterisation of fluoroquinolone resistance mechanisms in Enterobacteriaceae in Durban, South Africa
inferredcites →https://doi.org/10.1371/journal.pone.0179159openalex-snapshot
Polyamine transporter potABCD is required for virulence of encapsulated but not nonencapsulated Streptococcus pneumoniae
inferredcites →https://doi.org/10.1371/journal.ppat.1000541openalex-snapshot
Interplay in the Selection of Fluoroquinolone Resistance and Bacterial Fitness
inferredcites →https://doi.org/10.3201/eid0702.010239openalex-snapshot
Emerging Mechanisms of Fluoroquinolone Resistance
inferredcites →https://doi.org/10.3389/fmicb.2013.00125openalex-snapshot
Fluoroquinolone resistance mechanisms in an Escherichia coli isolate, HUE1, without quinolone resistance-determining region mutations
inferredcites →https://doi.org/10.3389/fmicb.2013.00242openalex-snapshot
High prevalence of fecal carriage of extended spectrum β-lactamase/AmpC-producing Enterobacteriaceae in cats and dogs
inferredcites →https://doi.org/10.3389/fmicb.2016.01234openalex-snapshot
Bacterial Communities: Interactions to Scale
inferredcites →https://doi.org/10.3389/fmicb.2017.01020openalex-snapshot
Predicting Species-Resolved Macronutrient Acquisition during Succession in a Model Phototrophic Biofilm Using an Integrated ‘Omics Approach
inferredcites →https://doi.org/10.3389/fmicb.2017.01899openalex-snapshot
Genetic Background and Expression of the New qepA4 Gene Variant Recovered in Clinical TEM-1- and CMY-2-Producing Escherichia coli
inferredcites →https://doi.org/10.7883/yoken.jjid.2014.153openalex-snapshot
Contribution of QnrA, a Plasmid-Mediated Quinolone Resistance Peptide, to Survival of Escherichia coli Exposed to a Lethal Ciprofloxacin Concentration
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Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1007/978-981-13-9871-1_12openalex-snapshot
Efflux Pump Inhibitors and Their Role in the Reversal of Drug Resistance
inferred← citeshttps://doi.org/10.1371/journal.pcbi.1008106openalex-snapshot
Drug-target binding quantitatively predicts optimal antibiotic dose levels in quinolones
inferred← citeshttps://doi.org/10.24099/vet.arhiv.1814openalex-snapshot
Phenotypic and genotypic investigation of antimicrobial resistance and extended-spectrum beta-lactamase production among Escherichia coli isolated from bovine mastitis
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