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Mutation of sequences flanking and separating transcription factor binding sites in a Drosophila enhancer significantly alter its output
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/j.1460-2075.1992.tb05498.xopenalex-snapshot
Regulation of even‐skipped stripe 2 in the Drosophila embryo.
inferredcites →https://doi.org/10.1002/j.1460-2075.1995.tb07255.xopenalex-snapshot
Poly(dA:dT), a ubiquitous promoter element that stimulates transcription via its intrinsic DNA structure.
inferredcites →https://doi.org/10.1006/geno.2000.6451openalex-snapshot
A Highly Efficient Escherichia coli-Based Chromosome Engineering System Adapted for Recombinogenic Targeting and Subcloning of BAC DNA
inferredcites →https://doi.org/10.1016/0092-8674(88)90182-1openalex-snapshot
A gradient of bicoid protein in Drosophila embryos
inferredcites →https://doi.org/10.1016/0092-8674(89)90062-7openalex-snapshot
The gradient morphogen bicoid is a concentration-dependent transcriptional activator
inferredcites →https://doi.org/10.1016/0092-8674(89)90916-1openalex-snapshot
Early and late periodic patterns of even skipped expression are controlled by distinct regulatory elements that respond to different spatial cues
inferredcites →https://doi.org/10.1016/0378-1119(89)90359-4openalex-snapshot
Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension
inferredcites →https://doi.org/10.1016/j.cell.2007.05.019openalex-snapshot
An Atomic Model of the Interferon-β Enhanceosome
inferredcites →https://doi.org/10.1016/j.cell.2010.10.004openalex-snapshot
Pausing of RNA Polymerase II Disrupts DNA-Specified Nucleosome Organization to Enable Precise Gene Regulation
inferredcites →https://doi.org/10.1016/j.celrep.2013.03.014openalex-snapshot
Genomic Regions Flanking E-Box Binding Sites Influence DNA Binding Specificity of bHLH Transcription Factors through DNA Shape
inferredcites →https://doi.org/10.1016/j.celrep.2016.12.025openalex-snapshot
A Fully Synthetic Transcriptional Platform for a Multicellular Eukaryote
inferredcites →https://doi.org/10.1016/j.cub.2010.06.070openalex-snapshot
Transcriptional Enhancers in Animal Development and Evolution
inferredcites →https://doi.org/10.1016/j.molcel.2006.10.018openalex-snapshot
Relationships between p63 Binding, DNA Sequence, Transcription Activity, and Biological Function in Human Cells
inferredcites →https://doi.org/10.1016/j.molcel.2014.04.006openalex-snapshot
Coregulation of Transcription Factor Binding and Nucleosome Occupancy through DNA Features of Mammalian Enhancers
inferredcites →https://doi.org/10.1016/j.tibs.2014.07.002openalex-snapshot
Absence of a simple code: how transcription factors read the genome
inferredcites →https://doi.org/10.1016/j.tig.2009.08.003openalex-snapshot
Different gene regulation strategies revealed by analysis of binding motifs
inferredcites →https://doi.org/10.1016/s0070-2153(09)88003-4openalex-snapshot
Chapter 3 Hox Specificity
inferredcites →https://doi.org/10.1038/332281a0openalex-snapshot
Regulation of the Drosophila segmentation gene hunchback by two maternal morphogenetic centres
inferredcites →https://doi.org/10.1038/337138a0openalex-snapshot
The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo
inferredcites →https://doi.org/10.1038/340363a0openalex-snapshot
Determination of spatial domains of zygotic gene expression in the Drosophila embryo by the affinity of binding sites for the bicoid morphogen
inferredcites →https://doi.org/10.1038/35054095openalex-snapshot
Genomic binding sites of the yeast cell-cycle transcription factors SBF and MBF
inferredcites →https://doi.org/10.1038/nature11232openalex-snapshot
The accessible chromatin landscape of the human genome
inferredcites →https://doi.org/10.1038/nature15518openalex-snapshot
DNA-dependent formation of transcription factor pairs alters their binding specificity
inferredcites →https://doi.org/10.1038/nature18912openalex-snapshot
DNA-dependent formation of transcription factor pairs alters their binding specificity
inferredcites →https://doi.org/10.1038/ng.2305openalex-snapshot
Manipulating nucleosome disfavoring sequences allows fine-tune regulation of gene expression in yeast
inferredcites →https://doi.org/10.1038/nmeth.1331openalex-snapshot
Versatile P[acman] BAC libraries for transgenesis studies in Drosophila melanogaster
inferredcites →https://doi.org/10.1038/nrg3207openalex-snapshot
Transcription factors: from enhancer binding to developmental control
inferredcites →https://doi.org/10.1039/c5ib00321kopenalex-snapshot
The appeasement of Doug: a synthetic approach to enhancer biology
inferredcites →https://doi.org/10.1073/pnas.0913805107openalex-snapshot
Nucleosome-mediated cooperativity between transcription factors
inferredcites →https://doi.org/10.1073/pnas.1109873108openalex-snapshot
Multiple enhancers ensure precision of gap gene-expression patterns in the Drosophila embryo
inferredcites →https://doi.org/10.1093/bioinformatics/15.7.563openalex-snapshot
Identifying DNA and protein patterns with statistically significant alignments of multiple sequences.
inferredcites →https://doi.org/10.1093/molbev/msn072openalex-snapshot
Fast Evolution of Core Promoters in Primate Genomes
inferredcites →https://doi.org/10.1093/nar/gkv978openalex-snapshot
Genome-wide profiling of nucleosome sensitivity and chromatin accessibility in Drosophila melanogaster
inferredcites →https://doi.org/10.1093/nar/gni035openalex-snapshot
Simple and highly efficient BAC recombineering using galK selection
inferredcites →https://doi.org/10.1101/gad.176826.111openalex-snapshot
Pioneer transcription factors: establishing competence for gene expression
inferredcites →https://doi.org/10.1101/gad.234534.113openalex-snapshot
Impacts of the ubiquitous factor Zelda on Bicoid-dependent DNA binding and transcription in Drosophila
inferredcites →https://doi.org/10.1101/gad.5.5.827openalex-snapshot
Transcriptional regulation of a pair-rule stripe in Drosophila.
inferredcites →https://doi.org/10.1101/gr.138776.112openalex-snapshot
CpG islands and GC content dictate nucleosome depletion in a transcription-independent manner at mammalian promoters
inferredcites →https://doi.org/10.1101/gr.151472.112openalex-snapshot
Global analysis of Drosophila Cys2-His2 zinc finger proteins reveals a multitude of novel recognition motifs and binding determinants
inferredcites →https://doi.org/10.1101/gr.169243.113openalex-snapshot
Dissection of thousands of cell type-specific enhancers identifies dinucleotide repeat motifs as general enhancer features
inferredcites →https://doi.org/10.1101/gr.185033.114openalex-snapshot
Unraveling determinants of transcription factor binding outside the core binding site
inferredcites →https://doi.org/10.1101/gr.5655606openalex-snapshot
Whole-genome comparison of Leu3 binding in vitro and in vivo reveals the importance of nucleosome occupancy in target site selection
inferredcites →https://doi.org/10.1101/gr.749203openalex-snapshot
A Highly Efficient Recombineering-Based Method for Generating Conditional Knockout Mutations
inferredcites →https://doi.org/10.1126/science.1099247openalex-snapshot
Multiplex Detection of RNA Expression in Drosophila Embryos
inferredcites →https://doi.org/10.1126/science.1134426openalex-snapshot
P[acman]: A BAC Transgenic Platform for Targeted Insertion of Large DNA Fragments in D. melanogaster
inferredcites →https://doi.org/10.1126/science.1683715openalex-snapshot
Regulation of a Segmentation Stripe by Overlapping Activators and Repressors in the Drosophila Embryo
inferredcites →https://doi.org/10.1126/science.aac6948openalex-snapshot
Suboptimization of developmental enhancers
inferredcites →https://doi.org/10.1128/mcb.23.5.1623-1632.2003openalex-snapshot
Collaborative Competition Mechanism for Gene Activation In Vivo
inferredcites →https://doi.org/10.1146/annurev-genet-110711-155437openalex-snapshot
Disentangling the Many Layers of Eukaryotic Transcriptional Regulation
inferredcites →https://doi.org/10.1186/1471-2105-10-442openalex-snapshot
G+C content dominates intrinsic nucleosome occupancy
inferredcites →https://doi.org/10.1186/gb-2009-10-7-r80openalex-snapshot
Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions
inferredcites →https://doi.org/10.1242/dev.122.1.205openalex-snapshot
The eve stripe 2 enhancer employs multiple modes of transcriptional synergy
inferredcites →https://doi.org/10.1371/journal.pbio.0060027openalex-snapshot
Transcription Factors Bind Thousands of Active and Inactive Regions in the Drosophila Blastoderm
inferredcites →https://doi.org/10.1371/journal.pgen.1002266openalex-snapshot
Zelda Binding in the Early Drosophila melanogaster Embryo Marks Regions Subsequently Activated at the Maternal-to-Zygotic Transition
inferredcites →https://doi.org/10.1371/journal.pgen.1005889openalex-snapshot
Determinants of Chromosome Architecture: Insulator Pairing in cis and in trans
inferredcites →https://doi.org/10.7554/elife.28275openalex-snapshot
Concentration dependent chromatin states induced by the bicoid morphogen gradient
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1111/1751-7915.13868openalex-snapshot
Importance of the 5′ regulatory region to bacterial synthetic biology applications
inferred← citeshttps://doi.org/10.1534/g3.120.401777openalex-snapshot
A Mutation in the Drosophila melanogaster eve Stripe 2 Minimal Enhancer Is Buffered by Flanking Sequences
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