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Inferring metabolite interactomes via molecular structure informed Bayesian graphical model selection with an application to coronary artery disease

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Circulating levels of plasminogen and oxidized phospholipids bound to plasminogen distinguish between atherothrombotic and non-atherothrombotic myocardial infarction

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Distinguishing between the metabolome and xenobiotic exposome in environmental field samples analysed by direct-infusion mass spectrometry based metabolomics and lipidomics

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Molecular phenotyping of a UK population: defining the human serum metabolome

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Metabolomic changes during cellular transformation monitored by metabolite–metabolite correlation analysis and correlated with gene expression

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Effect of gut microbiota on host whole metabolome

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Reconstruction and analysis of correlation networks based on GC–MS metabolomics data for young hypertensive men

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Metabolic effects of intestinal absorption and enterohepatic cycling of bile acids

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Bile acid sequestration normalizes plasma cholesterol and reduces atherosclerosis in hypercholesterolemic mice. No additional effect of physical activity

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Dynamic Metabolomics Reveals that Insulin Primes the Adipocyte for Glucose Metabolism

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Deoxycholyltaurine-induced vasodilation of rodent aorta is nitric oxide- and muscarinic M3 receptor-dependent

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The Myth of the “Vulnerable Plaque”

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Comprehensive Metabolomic Characterization of Coronary Artery Diseases

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Generating random correlation matrices based on vines and extended onion method

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Systems characterization of differential plasma metabolome perturbations following thrombotic and non-thrombotic myocardial infarction

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Plasma and Serum Metabolite Association Networks: Comparability within and between Studies Using NMR and MS Profiling

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Performance of Similarity Measures in 2D Fragment-Based Similarity Searching: Comparison of Structural Descriptors and Similarity Coefficients

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Network-based prediction of human tissue-specific metabolism

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An atlas of genetic influences on human blood metabolites

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Chemical Similarity Enrichment Analysis (ChemRICH) as alternative to biochemical pathway mapping for metabolomic datasets

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The human circadian metabolome

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MetPA: a web-based metabolomics tool for pathway analysis and visualization

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On Scale Mixtures of Normal Distributions

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Model selection and estimation in the Gaussian graphical model

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Sparse inverse covariance estimation with the graphical lasso

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KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGG as a reference resource for gene and protein annotation

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Bile Acids Regulate Cardiovascular Function

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Somatic mutation in cancer and normal cells

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Bile acids induce arrhythmias in human atrial myocardium—implications for altered serum bile acid composition in patients with atrial fibrillation

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Model Selection Through Sparse Maximum Likelihood Estimation for Multivariate Gaussian or Binary Data

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The Enzymes, Regulation, and Genetics of Bile Acid Synthesis

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Heart Disease and Stroke Statistics—2017 Update: A Report From the American Heart Association

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Epigenetics and Metabolism

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MetaMapp: mapping and visualizing metabolomic data by integrating information from biochemical pathways and chemical and mass spectral similarity

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Gaussian graphical modeling reconstructs pathway reactions from high-throughput metabolomics data

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A novel untargeted metabolomics correlation-based network analysis incorporating human metabolic reconstructions

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DNA methylation changes of whole blood cells in response to active smoking exposure in adults: a systematic review of DNA methylation studies

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Targeted profiling of circulating and hepatic bile acids in human, mouse, and rat using a UPLC-MRM-MS-validated method

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Bile salts of vertebrates: structural variation and possible evolutionary significance

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High-dimensional graphs and variable selection with the Lasso

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Network exploration via the adaptive LASSO and SCAD penalties

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Bayesian Graphical Lasso Models and Efficient Posterior Computation

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Identification of a plasma metabolomic signature of thrombotic myocardial infarction that is distinct from non-thrombotic myocardial infarction and stable coronary artery disease

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Development and in silico evaluation of large-scale metabolite identification methods using functional group detection for metabolomics

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Inferring metabolic networks using the Bayesian adaptive graphical lasso with informative priors

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Harrison's Principles of Internal Medicine.

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2172/1888206openalex-snapshot

Leveraging GCxGC-TOFMS to explore plant-soil-microbiome interactions in Maize [Slides]

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