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ICTD: A semi-supervised cell type identification and deconvolution method for multi-omics data

https://doi.org/10.1101/426593
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/s00262-018-2150-zopenalex-snapshot
Quantifying tumor-infiltrating immune cells from transcriptomics data
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MRHCA: a nonparametric statistics based method for hub and co‐expression module identification in large gene co‐expression network
inferredcites →https://doi.org/10.1016/j.celrep.2018.03.086openalex-snapshot
Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images
inferredcites →https://doi.org/10.1038/nmeth.3337openalex-snapshot
Robust enumeration of cell subsets from tissue expression profiles
inferredcites →https://doi.org/10.1038/nrg.2016.67openalex-snapshot
Computational genomics tools for dissecting tumour–immune cell interactions
inferredcites →https://doi.org/10.1038/nri2506openalex-snapshot
Myeloid-derived suppressor cells as regulators of the immune system
inferredcites →https://doi.org/10.1038/s41467-018-07242-6openalex-snapshot
Leveraging heterogeneity across multiple datasets increases cell-mixture deconvolution accuracy and reduces biological and technical biases
inferredcites →https://doi.org/10.1038/s41467-018-08023-xopenalex-snapshot
Bulk tissue cell type deconvolution with multi-subject single-cell expression reference
inferredcites →https://doi.org/10.1038/s41587-019-0114-2openalex-snapshot
Determining cell type abundance and expression from bulk tissues with digital cytometry
inferredcites →https://doi.org/10.1038/s41591-018-0136-1openalex-snapshot
Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response
inferredcites →https://doi.org/10.1038/s41592-018-0229-2openalex-snapshot
Deep generative modeling for single-cell transcriptomics
inferredcites →https://doi.org/10.1038/s41592-019-0355-5openalex-snapshot
Cell composition analysis of bulk genomics using single-cell data
inferredcites →https://doi.org/10.1038/sj.gene.6364173openalex-snapshot
Immune response in silico (IRIS): immune-specific genes identified from a compendium of microarray expression data
inferredcites →https://doi.org/10.1093/biostatistics/kxj037openalex-snapshot
Adjusting batch effects in microarray expression data using empirical Bayes methods
inferredcites →https://doi.org/10.1093/jmcb/mjv031openalex-snapshot
Elucidation of drivers of high-level production of lactates throughout a cancer development
inferredcites →https://doi.org/10.1109/tsp.2013.2285514openalex-snapshot
Non-Negative Matrix Factorization Revisited: Uniqueness and Algorithm for Symmetric Decomposition
inferredcites →https://doi.org/10.1111/j.1600-0587.2012.07348.xopenalex-snapshot
Collinearity: a review of methods to deal with it and a simulation study evaluating their performance
inferredcites →https://doi.org/10.1126/science.1091903openalex-snapshot
MicroRNAs Modulate Hematopoietic Lineage Differentiation
inferredcites →https://doi.org/10.1126/science.aad0501openalex-snapshot
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
inferredcites →https://doi.org/10.1126/science.aai8478openalex-snapshot
Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq
inferredcites →https://doi.org/10.1158/0008-5472.can-16-2490openalex-snapshot
Systematic Pan-Cancer Analysis Reveals Immune Cell Interactions in the Tumor Microenvironment
inferredcites →https://doi.org/10.1158/2326-6074.tumimm17-b24openalex-snapshot
Abstract B24: Digital signatures of T cell dysfunction predict immunotherapy response
inferredcites →https://doi.org/10.1186/1471-2105-9-559openalex-snapshot
WGCNA: an R package for weighted correlation network analysis
inferredcites →https://doi.org/10.1186/s13059-015-0844-5openalex-snapshot
MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data
inferredcites →https://doi.org/10.1186/s13059-016-1028-7openalex-snapshot
Comprehensive analyses of tumor immunity: implications for cancer immunotherapy
inferredcites →https://doi.org/10.1186/s13059-017-1256-5openalex-snapshot
Revisit linear regression-based deconvolution methods for tumor gene expression data
inferredcites →https://doi.org/10.1186/s13059-019-1778-0openalex-snapshot
TOAST: improving reference-free cell composition estimation by cross-cell type differential analysis
inferredcites →https://doi.org/10.1371/journal.pone.0006098openalex-snapshot
Deconvolution of Blood Microarray Data Identifies Cellular Activation Patterns in Systemic Lupus Erythematosus
inferredcites →https://doi.org/10.3389/fimmu.2017.00892openalex-snapshot
CD56 in the Immune System: More Than a Marker for Cytotoxicity?
inferredcites →https://doi.org/10.7554/elife.26476openalex-snapshot
Simultaneous enumeration of cancer and immune cell types from bulk tumor gene expression data

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Inhibition of Glutamate‐to‐Glutathione Flux Promotes Tumor Antigen Presentation in Colorectal Cancer Cells
inferred← citeshttps://doi.org/10.1016/j.gpb.2022.06.003openalex-snapshot
Acid–Base Homeostasis and Implications to the Phenotypic Behaviors of Cancer
inferred← citeshttps://doi.org/10.1016/j.patter.2022.100440openalex-snapshot
DAISM-DNNXMBD: Highly accurate cell type proportion estimation with in silico data augmentation and deep neural networks
inferred← citeshttps://doi.org/10.1038/s41467-023-40611-4openalex-snapshot
Whole genome deconvolution unveils Alzheimer’s resilient epigenetic signature
inferred← citeshttps://doi.org/10.1093/bib/bbaa307openalex-snapshot
SSMD: a semi-supervised approach for a robust cell type identification and deconvolution of mouse transcriptomics data
inferred← citeshttps://doi.org/10.1172/jci140837openalex-snapshot
MAL2 drives immune evasion in breast cancer by suppressing tumor antigen presentation
inferred← citeshttps://doi.org/10.1186/s40001-025-03013-4openalex-snapshot
Deferoxamine addresses metabolic dysregulation and urinary tract infections in weight-associated gestational diabetes mellitus
inferred← citeshttps://doi.org/10.3390/biom11101501openalex-snapshot
Effects of Molecular Iodine/Chemotherapy in the Immune Component of Breast Cancer Tumoral Microenvironment
inferred← citeshttps://doi.org/10.70675/52e5031azbec1z427azadafzf0cbf809a35eopenalex-snapshot
Application of Multivariate Gaussian Convolution and Mixture Models for Identifying Key Biomarkers Underlying Variability in Transcriptomic Profiles and the Diversity of Therapeutic Responses
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