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Structural venomics: evolution of a complex chemical arsenal by massive duplication and neofunctionalization of a single ancestral fold

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/bies.201500165openalex-snapshot
Toxin structures as evolutionary tools: Using conserved 3D folds to study the evolution of rapidly evolving peptides
inferredcites →https://doi.org/10.1002/cbic.201000330openalex-snapshot
Chemical Synthesis and Structure of the Prokineticin Bv8
inferredcites →https://doi.org/10.1002/pro.5560031022openalex-snapshot
A common structural motif incorporating a cystine knot and a triple‐stranded β‐sheet in toxic and inhibitory polypeptides
inferredcites →https://doi.org/10.1002/prot.22054openalex-snapshot
Structure and folding of disulfide‐rich miniproteins: Insights from molecular dynamics simulations and MM‐PBSA free energy calculations
inferredcites →https://doi.org/10.1006/jmbi.1993.1626openalex-snapshot
Comparative Protein Modelling by Satisfaction of Spatial Restraints
inferredcites →https://doi.org/10.1007/978-1-4939-6887-9_10openalex-snapshot
A Strategy for Production of Correctly Folded Disulfide-Rich Peptides in the Periplasm of E. coli
inferredcites →https://doi.org/10.1007/s10858-007-9180-8openalex-snapshot
Automatic maximum entropy spectral reconstruction in NMR
inferredcites →https://doi.org/10.1007/s10858-009-9333-zopenalex-snapshot
TALOS+: a hybrid method for predicting protein backbone torsion angles from NMR chemical shifts
inferredcites →https://doi.org/10.1016/b978-0-12-387668-3.00001-5openalex-snapshot
Venom Composition and Strategies in Spiders
inferredcites →https://doi.org/10.1016/j.bcp.2013.02.030openalex-snapshot
The insecticidal neurotoxin Aps III is an atypical knottin peptide that potently blocks insect voltage-gated sodium channels
inferredcites →https://doi.org/10.1016/j.cell.2010.03.052openalex-snapshot
A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain
inferredcites →https://doi.org/10.1016/j.jmr.2010.02.012openalex-snapshot
A non-uniformly sampled 4D HCC(CO)NH-TOCSY experiment processed using maximum entropy for rapid protein sidechain assignment
inferredcites →https://doi.org/10.1016/j.jprot.2013.01.002openalex-snapshot
Unravelling the complex venom landscapes of lethal Australian funnel-web spiders (Hexathelidae: Atracinae) using LC-MALDI-TOF mass spectrometry
inferredcites →https://doi.org/10.1016/j.jprot.2017.07.007openalex-snapshot
Revisiting venom of the sea anemone Stichodactyla haddoni : Omics techniques reveal the complete toxin arsenal of a well-studied sea anemone genus
inferredcites →https://doi.org/10.1016/j.peptides.2005.05.012openalex-snapshot
Discovery of an MIT-like atracotoxin family: Spider venom peptides that share sequence homology but not pharmacological properties with AVIT family proteins
inferredcites →https://doi.org/10.1016/j.toxicon.2003.11.002openalex-snapshot
Excitement ahead: structure, function and mechanism of snake venom phospholipase A2 enzymes
inferredcites →https://doi.org/10.1016/j.toxicon.2004.02.007openalex-snapshot
Tarantulas: eight-legged pharmacists and combinatorial chemists
inferredcites →https://doi.org/10.1016/j.toxicon.2006.01.018openalex-snapshot
Venom landscapes: Mining the complexity of spider venoms via a combined cDNA and mass spectrometric approach
inferredcites →https://doi.org/10.1016/j.toxicon.2008.05.020openalex-snapshot
A rational nomenclature for naming peptide toxins from spiders and other venomous animals
inferredcites →https://doi.org/10.1016/s0041-0101(99)00174-9openalex-snapshot
Isolation of a funnel-web spider polypeptide with homology to mamba intestinal toxin 1 and the embryonic head inducer Dickkopf-1
inferredcites →https://doi.org/10.1021/pr400875sopenalex-snapshot
Spit and Venom from Scytodes Spiders: A Diverse and Distinct Cocktail
inferredcites →https://doi.org/10.1038/75921openalex-snapshot
Discovery and characterization of a family of insecticidal neurotoxins with a rare vicinal disulfide bridge
inferredcites →https://doi.org/10.1038/nbt.1883openalex-snapshot
Full-length transcriptome assembly from RNA-Seq data without a reference genome
inferredcites →https://doi.org/10.1038/nmeth.1701openalex-snapshot
SignalP 4.0: discriminating signal peptides from transmembrane regions
inferredcites →https://doi.org/10.1038/nsb0797-559openalex-snapshot
The structure of a novel insecticidal neurotoxin, ω-atracotoxin-HV1, from the venom of an Australian funnel web spider
inferredcites →https://doi.org/10.1039/9781849737876openalex-snapshot
Venoms to Drugs
inferredcites →https://doi.org/10.1039/9781849737876-00221openalex-snapshot
Chapter 8. Therapeutic Applications of Spider-Venom Peptides
inferredcites →https://doi.org/10.1073/pnas.0806840105openalex-snapshot
NMR-spectroscopic screening of spider venom reveals sulfated nucleosides as major components for the brown recluse and related species
inferredcites →https://doi.org/10.1073/pnas.1103501108openalex-snapshot
Unique scorpion toxin with a putative ancestral fold provides insight into evolution of the inhibitor cystine knot motif
inferredcites →https://doi.org/10.1073/pnas.1508380112openalex-snapshot
Unexpected features of the dark proteome
inferredcites →https://doi.org/10.1073/pnas.1614728114openalex-snapshot
Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a
inferredcites →https://doi.org/10.1073/pnas.1615484114openalex-snapshot
Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release
inferredcites →https://doi.org/10.1074/jbc.m001491200openalex-snapshot
Isolation and Characterization of Gomesin, an 18-Residue Cysteine-rich Defense Peptide from the Spider Acanthoscurria gomesiana Hemocytes with Sequence Similarities to Horseshoe Crab Antimicrobial Peptides of the Tachyplesin Family
inferredcites →https://doi.org/10.1074/mcp.m112.021469openalex-snapshot
Deep Venomics Reveals the Mechanism for Expanded Peptide Diversity in Cone Snail Venom
inferredcites →https://doi.org/10.1080/07313830500237166openalex-snapshot
A Note on the Evolution of Spider Toxins Containing the Ick-Motif
inferredcites →https://doi.org/10.1081/txr-120014409openalex-snapshot
STRUCTURE AND FUNCTION OF INSECTICIDAL NEUROTOXINS FROM AUSTRALIAN FUNNEL-WEB SPIDERS
inferredcites →https://doi.org/10.1093/bioinformatics/btg180openalex-snapshot
MrBayes 3: Bayesian phylogenetic inference under mixed models
inferredcites →https://doi.org/10.1093/bioinformatics/bti610openalex-snapshot
Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research
inferredcites →https://doi.org/10.1093/bioinformatics/btu170openalex-snapshot
Trimmomatic: a flexible trimmer for Illumina sequence data
inferredcites →https://doi.org/10.1093/bioinformatics/btx661openalex-snapshot
ArachnoServer 3.0: an online resource for automated discovery, analysis and annotation of spider toxins
inferredcites →https://doi.org/10.1093/molbev/mst010openalex-snapshot
MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability
inferredcites →https://doi.org/10.1093/molbev/mst024openalex-snapshot
Ultrafast Approximation for Phylogenetic Bootstrap
inferredcites →https://doi.org/10.1093/molbev/msu235openalex-snapshot
Phylogenomic Interrogation of Arachnida Reveals Systemic Conflicts in Phylogenetic Signal
inferredcites →https://doi.org/10.1093/molbev/msu300openalex-snapshot
IQ-TREE: A Fast and Effective Stochastic Algorithm for Estimating Maximum-Likelihood Phylogenies
inferredcites →https://doi.org/10.1093/molbev/msw106openalex-snapshot
The Defensins Consist of Two Independent, Convergent Protein Superfamilies
inferredcites →https://doi.org/10.1093/nar/18.20.6097openalex-snapshot
Sequence logos: a new way to display consensus sequences
inferredcites →https://doi.org/10.1098/rstb.2015.0133openalex-snapshot
A molecular palaeobiological exploration of arthropod terrestrialization
inferredcites →https://doi.org/10.1101/gr.1917404openalex-snapshot
Using the miraEST Assembler for Reliable and Automated mRNA Transcript Assembly and SNP Detection in Sequenced ESTs
inferredcites →https://doi.org/10.1107/s0907444909042073openalex-snapshot
MolProbity : all-atom structure validation for macromolecular crystallography
inferredcites →https://doi.org/10.1111/febs.13189openalex-snapshot
The insecticidal spider toxin SFI 1 is a knottin peptide that blocks the pore of insect voltage‐gated sodium channels via a large β‐hairpin loop
inferredcites →https://doi.org/10.1111/imb.12097openalex-snapshot
Structure of the yellow sac spider C heiracanthium punctorium genes provides clues to evolution of insecticidal two‐domain knottin toxins
inferredcites →https://doi.org/10.1111/j.1365-2583.2009.00914.xopenalex-snapshot
Insights into the venom composition of the ectoparasitoid wasp Nasonia vitripennis from bioinformatic and proteomic studies
inferredcites →https://doi.org/10.1134/s0006297909130069openalex-snapshot
Molecular diversity of spider venom
inferredcites →https://doi.org/10.1146/annurev-ento-120811-153650openalex-snapshot
Spider-Venom Peptides: Structure, Pharmacology, and Potential for Control of Insect Pests
inferredcites →https://doi.org/10.1146/annurev.genom.9.081307.164356openalex-snapshot
The Toxicogenomic Multiverse: Convergent Recruitment of Proteins Into Animal Venoms
inferredcites →https://doi.org/10.1186/1471-2105-10-1openalex-snapshot
Regularized gene selection in cancer microarray meta-analysis
inferredcites →https://doi.org/10.1186/1471-2105-12-323openalex-snapshot
RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
inferredcites →https://doi.org/10.1186/1471-2164-11-693openalex-snapshot
The venom composition of the parasitic wasp Chelonus inanitus resolved by combined expressed sequence tags analysis and proteomic approach
inferredcites →https://doi.org/10.1186/1471-2164-15-177openalex-snapshot
Diversification of a single ancestral gene into a successful toxin superfamily in highly venomous Australian funnel-web spiders
inferredcites →https://doi.org/10.1186/1756-0500-3-3openalex-snapshot
CANGS: a user-friendly utility for processing and analyzing 454 GS-FLX data in biodiversity studies
inferredcites →https://doi.org/10.1186/2047-217x-4-1openalex-snapshot
SmileFinder: a resampling-based approach to evaluate signatures of selection from genome-wide sets of matching allele frequency data in two or more diploid populations
inferredcites →https://doi.org/10.1371/journal.pbio.1001127openalex-snapshot
How Many Species Are There on Earth and in the Ocean?
inferredcites →https://doi.org/10.1371/journal.pone.0003414openalex-snapshot
Discovery of a Distinct Superfamily of Kunitz-Type Toxin (KTT) from Tarantulas
inferredcites →https://doi.org/10.1371/journal.pone.0063865openalex-snapshot
Production of Recombinant Disulfide-Rich Venom Peptides for Structural and Functional Analysis via Expression in the Periplasm of E. coli
inferredcites →https://doi.org/10.1371/journal.pone.0140829openalex-snapshot
Genomics Virtual Laboratory: A Practical Bioinformatics Workbench for the Cloud
inferredcites →https://doi.org/10.1371/journal.pone.0143963openalex-snapshot
Isolation, N-glycosylations and Function of a Hyaluronidase-Like Enzyme from the Venom of the Spider Cupiennius salei
inferredcites →https://doi.org/10.1385/1-59259-809-9:353openalex-snapshot
Automated NMR Structure Calculation With CYANA
inferredcites →https://doi.org/10.1517/14712598.2011.621940openalex-snapshot
Venoms as a platform for human drugs: translating toxins into therapeutics
inferredcites →https://doi.org/10.2174/138161211798999465openalex-snapshot
Natural and Engineered Cystine Knot Miniproteins for Diagnostic and Therapeutic Applications
inferredcites →https://doi.org/10.3390/toxins7104366openalex-snapshot
The Cystine Knot Is Responsible for the Exceptional Stability of the Insecticidal Spider Toxin ω-Hexatoxin-Hv1a

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Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1042/bst20190820openalex-snapshot
The evolutionary dynamics of venom toxins made by insects and other animals
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