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Enhancing Cardiac Reprogramming by Suppressing Specific C-C Chemokine Signaling Pathways

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Discovery of Nonsteroidal Anti-Inflammatory Drug and Anticancer Drug Enhancing Reprogramming and Induced Pluripotent Stem Cell Generation

inferredcites →https://doi.org/10.1002/wsbm.112openalex-snapshot

Signaling pathways in early cardiac development

inferredcites →https://doi.org/10.1016/j.cell.2010.07.002openalex-snapshot

Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors

inferredcites →https://doi.org/10.1016/j.celrep.2014.01.038openalex-snapshot

Small Molecules Enable Cardiac Reprogramming of Mouse Fibroblasts with a Single Factor, Oct4

inferredcites →https://doi.org/10.1016/j.ijcard.2015.06.017openalex-snapshot

Clinical outcomes of multiple chronic total occlusions in coronary arteries according to three therapeutic strategies: Bypass surgery, percutaneous intervention and medication

inferredcites →https://doi.org/10.1016/j.scr.2017.06.015openalex-snapshot

CXCR4 and CXCR7 play distinct roles in cardiac lineage specification and pharmacologic β-adrenergic response

inferredcites →https://doi.org/10.1016/j.stem.2016.02.003openalex-snapshot

Bmi1 Is a Key Epigenetic Barrier to Direct Cardiac Reprogramming

inferredcites →https://doi.org/10.1016/j.stemcr.2013.07.005openalex-snapshot

Direct Reprogramming of Human Fibroblasts toward a Cardiomyocyte-like State

inferredcites →https://doi.org/10.1016/j.stemcr.2015.10.019openalex-snapshot

Fibroblast Growth Factors and Vascular Endothelial Growth Factor Promote Cardiac Reprogramming under Defined Conditions

inferredcites →https://doi.org/10.1016/j.stemcr.2017.01.025openalex-snapshot

Notch Inhibition Enhances Cardiac Reprogramming by Increasing MEF2C Transcriptional Activity

inferredcites →https://doi.org/10.1016/j.yjmcc.2013.04.004openalex-snapshot

Optimization of direct fibroblast reprogramming to cardiomyocytes using calcium activity as a functional measure of success

inferredcites →https://doi.org/10.1038/celldisc.2016.36openalex-snapshot

Targeting Mll1 H3K4 methyltransferase activity to guide cardiac lineage specific reprogramming of fibroblasts

inferredcites →https://doi.org/10.1038/cr.2015.99openalex-snapshot

Direct reprogramming of mouse fibroblasts into cardiomyocytes with chemical cocktails

inferredcites →https://doi.org/10.1038/nature11044openalex-snapshot

In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes

inferredcites →https://doi.org/10.1038/nature11139openalex-snapshot

Heart repair by reprogramming non-myocytes with cardiac transcription factors

inferredcites →https://doi.org/10.1038/nature24454openalex-snapshot

Single-cell transcriptomics reconstructs fate conversion from fibroblast to cardiomyocyte

inferredcites →https://doi.org/10.1038/nbt.3519openalex-snapshot

Near-optimal probabilistic RNA-seq quantification

inferredcites →https://doi.org/10.1038/ncomms9243openalex-snapshot

High-efficiency reprogramming of fibroblasts into cardiomyocytes requires suppression of pro-fibrotic signalling

inferredcites →https://doi.org/10.1038/nm.3418openalex-snapshot

Self-renewal as a therapeutic target in human colorectal cancer

inferredcites →https://doi.org/10.1038/nrd.2017.106openalex-snapshot

Heart regeneration and repair after myocardial infarction: translational opportunities for novel therapeutics

inferredcites →https://doi.org/10.1038/srep40285openalex-snapshot

Core Transcription Factors, MicroRNAs, and Small Molecules Drive Transdifferentiation of Human Fibroblasts Towards The Cardiac Cell Lineage

inferredcites →https://doi.org/10.1073/pnas.1304053110openalex-snapshot

Induction of human cardiomyocyte-like cells from fibroblasts by defined factors

inferredcites →https://doi.org/10.1073/pnas.1516237112openalex-snapshot

Akt1/protein kinase B enhances transcriptional reprogramming of fibroblasts to functional cardiomyocytes

inferredcites →https://doi.org/10.1093/hmg/ddt358openalex-snapshot

WT1 regulates the expression of inhibitory chemokines during heart development

inferredcites →https://doi.org/10.1101/gad.305482.117openalex-snapshot

ZNF281 enhances cardiac reprogramming by modulating cardiac and inflammatory gene expression

inferredcites →https://doi.org/10.1126/science.aaf1502openalex-snapshot

Conversion of human fibroblasts into functional cardiomyocytes by small molecules

inferredcites →https://doi.org/10.1155/2018/3814747openalex-snapshot

A Loss of Function Screen of Epigenetic Modifiers and Splicing Factors during Early Stage of Cardiac Reprogramming

inferredcites →https://doi.org/10.1161/cir.0000000000000485openalex-snapshot

Heart Disease and Stroke Statistics—2017 Update: A Report From the American Heart Association

inferredcites →https://doi.org/10.1161/circresaha.112.269035openalex-snapshot

MicroRNA-Mediated In Vitro and In Vivo Direct Reprogramming of Cardiac Fibroblasts to Cardiomyocytes

inferredcites →https://doi.org/10.1161/circresaha.116.304510openalex-snapshot

MicroRNA Induced Cardiac Reprogramming In Vivo

inferredcites →https://doi.org/10.1161/circresaha.116.305547openalex-snapshot

Stoichiometry of Gata4, Mef2c, and Tbx5 Influences the Efficiency and Quality of Induced Cardiac Myocyte Reprogramming

inferredcites →https://doi.org/10.1161/circresaha.116.308741openalex-snapshot

Demethylation of H3K27 Is Essential for the Induction of Direct Cardiac Reprogramming by miR Combo

inferredcites →https://doi.org/10.1161/circulationaha.116.024692openalex-snapshot

Chemical Enhancement of In Vitro and In Vivo Direct Cardiac Reprogramming

inferredcites →https://doi.org/10.1164/rccm.200502-244ocopenalex-snapshot

Role of the Chemokine Receptors CXCR3 and CCR4 in Human Pulmonary Fibrosis

inferredcites →https://doi.org/10.1172/jci37444openalex-snapshot

CCR1 and CCR5 promote hepatic fibrosis in mice

inferredcites →https://doi.org/10.1177/10454411950060020101openalex-snapshot

Chemokines, a Family of Chemotactic Cytokines

inferredcites →https://doi.org/10.1182/blood-2008-08-175869openalex-snapshot

Activation of Wnt5A signaling is required for CXC chemokine ligand 12–mediated T-cell migration

inferredcites →https://doi.org/10.1186/1471-213x-7-54openalex-snapshot

The chemokine Sdf-1 and its receptor Cxcr4 are required for formation of muscle in zebrafish

inferredcites →https://doi.org/10.1371/journal.pone.0005824openalex-snapshot

Fgf and Sdf-1 Pathways Interact during Zebrafish Fin Regeneration

inferredcites →https://doi.org/10.1371/journal.pone.0024351openalex-snapshot

Molecular Insights into Reprogramming-Initiation Events Mediated by the OSKM Gene Regulatory Network

inferredcites →https://doi.org/10.1371/journal.pone.0063577openalex-snapshot

Transcription Factors MYOCD, SRF, Mesp1 and SMARCD3 Enhance the Cardio-Inducing Effect of GATA4, TBX5, and MEF2C during Direct Cellular Reprogramming

inferredcites →https://doi.org/10.1371/journal.pone.0089678openalex-snapshot

Inhibition of TGFβ Signaling Increases Direct Conversion of Fibroblasts to Induced Cardiomyocytes

inferredcites →https://doi.org/10.1371/journal.pone.0183000openalex-snapshot

Single cell qPCR reveals that additional HAND2 and microRNA-1 facilitate the early reprogramming progress of seven-factor-induced human myocytes

inferredcites →https://doi.org/10.15252/embj.201387605openalex-snapshot

MiR‐133 promotes cardiac reprogramming by directly repressing Snai1 and silencing fibroblast signatures

inferredcites →https://doi.org/10.2174/13816128113199990449openalex-snapshot

Targeting the Chemokines in Cardiac Repair

inferredcites →https://doi.org/10.3390/ijms18081805openalex-snapshot

Single-Construct Polycistronic Doxycycline-Inducible Vectors Improve Direct Cardiac Reprogramming and Can Be Used to Identify the Critical Timing of Transgene Expression

inferredcites →https://doi.org/10.3791/3854openalex-snapshot

Preparation of Mouse Embryonic Fibroblast Cells Suitable for Culturing Human Embryonic and Induced Pluripotent Stem Cells

inferredcites →https://doi.org/10.3791/53426openalex-snapshot

Improved Generation of Induced Cardiomyocytes Using a Polycistronic Construct Expressing Optimal Ratio of Gata4, Mef2c and Tbx5

inferredcites →https://doi.org/10.4049/jimmunol.173.7.4692openalex-snapshot

The Role of the Th2 CC Chemokine Ligand CCL17 in Pulmonary Fibrosis

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1007/5584_2022_760openalex-snapshot

Direct Cardiac Reprogramming: Current Status and Future Prospects

inferred← citeshttps://doi.org/10.1007/978-1-0716-1084-8_3openalex-snapshot

Production of Cardiomyocyte-Like Cells by Fibroblast Reprogramming with Defined Factors

inferred← citeshttps://doi.org/10.3390/cells8070679openalex-snapshot

Ameliorating the Fibrotic Remodeling of the Heart through Direct Cardiac Reprogramming

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