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Mutagenesis of orco impairs foraging but not oviposition in the hawkmoth Manduca sexta

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1 of the 117 references listed on this page is in the Retraction Watch database as retracted (export 2026-11-04): 10.7554/elife.12248 (notice 2018-04-12).

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/arch.940100403openalex-snapshot
Pheromone receptor cells in the male moth Manduca sexta
inferredcites →https://doi.org/10.1002/ecy.1846openalex-snapshot
Precipitation affects plant communication and defense
inferredcites →https://doi.org/10.1002/mrd.21091openalex-snapshot
The molecular machinery of germ line specification
inferredcites →https://doi.org/10.1006/anbe.2002.4010openalex-snapshot
Synergy between visual and olfactory cues in nectar feeding by naıve hawkmoths, Manduca sexta
inferredcites →https://doi.org/10.1007/978-3-319-33498-1openalex-snapshot
Deciphering Chemical Language of Plant Communication
inferredcites →https://doi.org/10.1007/978-3-319-33498-1_1openalex-snapshot
Temporal Dynamics of Plant Volatiles: Mechanistic Bases and Functional Consequences
inferredcites →https://doi.org/10.1007/bf00297081openalex-snapshot
10.1007/BF00297081
inferredcites →https://doi.org/10.1007/bf00318442openalex-snapshot
Sensory organs of the thoracic legs of the moth Manduca sexta
inferredcites →https://doi.org/10.1007/s00114-004-0532-xopenalex-snapshot
Floral CO2 emission may indicate food abundance to nectar-feeding moths
inferredcites →https://doi.org/10.1007/s00265-004-0865-7openalex-snapshot
Complex signal function: developing a framework of testable hypotheses
inferredcites →https://doi.org/10.1007/s00359-003-0427-xopenalex-snapshot
A candidate olfactory receptor subtype highly conserved across different insect orders
inferredcites →https://doi.org/10.1007/s00359-005-0081-6openalex-snapshot
The relative importance of olfaction and vision in a diurnal and a nocturnal hawkmoth
inferredcites →https://doi.org/10.1007/s00359-013-0837-3openalex-snapshot
The role of the coreceptor Orco in insect olfactory transduction
inferredcites →https://doi.org/10.1007/s003590000165openalex-snapshot
Responses of a population of antennal olfactory receptor cells in the female moth Manduca sexta to plant-associated volatile organic compounds
inferredcites →https://doi.org/10.1007/s00427-005-0033-8openalex-snapshot
Expression pattern of Bombyx vasa-like (BmVLG) protein and its implications in germ cell development
inferredcites →https://doi.org/10.1007/s004420000389openalex-snapshot
Ecophysiological comparison of direct and indirect defenses in Nicotiana attenuata
inferredcites →https://doi.org/10.1007/s10886-007-9375-1openalex-snapshot
Variation in Herbivore and Methyl Jasmonate-Induced Volatiles Among Genetic Lines of Datura wrightii
inferredcites →https://doi.org/10.1007/s10886-008-9484-5openalex-snapshot
Navigational Strategies Used by Insects to Find Distant, Wind-Borne Sources of Odor
inferredcites →https://doi.org/10.1007/s10886-008-9490-7openalex-snapshot
Physical Processes and Real-Time Chemical Measurement of the Insect Olfactory Environment
inferredcites →https://doi.org/10.1007/s10886-012-0168-9openalex-snapshot
Abiotic Induction Affects the Costs and Benefits of Inducible Herbivore Defenses in Datura wrightii
inferredcites →https://doi.org/10.1016/0022-1910(88)90054-6openalex-snapshot
Host finding by moths: Sensory modalities and behaviours
inferredcites →https://doi.org/10.1016/0031-9422(88)80598-3openalex-snapshot
A strophanthidin glycoside in siberian wallflower: A contact deterrent for the large white butterfly
inferredcites →https://doi.org/10.1016/j.anbehav.2004.04.015openalex-snapshot
Synergy between visual and olfactory cues in nectar feeding by wild hawkmoths, Manduca sexta
inferredcites →https://doi.org/10.1016/j.cell.2008.12.001openalex-snapshot
Variant Ionotropic Glutamate Receptors as Chemosensory Receptors in Drosophila
inferredcites →https://doi.org/10.1016/j.cell.2013.12.044openalex-snapshot
Multimodal Integration of Carbon Dioxide and Other Sensory Cues Drives Mosquito Attraction to Humans
inferredcites →https://doi.org/10.1016/j.cell.2017.06.051openalex-snapshot
An Engineered orco Mutation Produces Aberrant Social Behavior and Defective Neural Development in Ants
inferredcites →https://doi.org/10.1016/j.cell.2017.07.001openalex-snapshot
orco Mutagenesis Causes Loss of Antennal Lobe Glomeruli and Impaired Social Behavior in Ants
inferredcites →https://doi.org/10.1016/j.celrep.2018.01.082openalex-snapshot
Spatial Representation of Feeding and Oviposition Odors in the Brain of a Hawkmoth
inferredcites →https://doi.org/10.1016/j.cub.2005.02.007openalex-snapshot
Functional conservation of an insect odorant receptor gene across 250 million years of evolution
inferredcites →https://doi.org/10.1016/j.cub.2009.01.041openalex-snapshot
Characterization and Coding of Behaviorally Significant Odor Mixtures
inferredcites →https://doi.org/10.1016/j.ibmb.2008.05.002openalex-snapshot
Drosophila odorant receptors are novel seven transmembrane domain proteins that can signal independently of heterotrimeric G proteins
inferredcites →https://doi.org/10.1016/j.ibmb.2013.02.007openalex-snapshot
Ionotropic Receptors (IRs): Chemosensory ionotropic glutamate receptors in Drosophila and beyond
inferredcites →https://doi.org/10.1016/j.ibmb.2015.09.007openalex-snapshot
A reference gene set for chemosensory receptor genes of Manduca sexta
inferredcites →https://doi.org/10.1016/j.ibmb.2016.10.003openalex-snapshot
CRISPR/Cas9 in locusts: Successful establishment of an olfactory deficiency line by targeting the mutagenesis of an odorant receptor co-receptor (Orco)
inferredcites →https://doi.org/10.1016/j.ibmb.2017.05.007openalex-snapshot
Deletion of the Bombyx mori odorant receptor co-receptor (BmOrco) impairs olfactory sensitivity in silkworms
inferredcites →https://doi.org/10.1016/j.neuron.2004.08.019openalex-snapshot
Or83b Encodes a Broadly Expressed Odorant Receptor Essential for Drosophila Olfaction
inferredcites →https://doi.org/10.1016/j.neuron.2011.11.003openalex-snapshot
Evolution of Insect Olfaction
inferredcites →https://doi.org/10.1016/j.tplants.2009.12.002openalex-snapshot
The evolutionary context for herbivore-induced plant volatiles: beyond the ‘cry for help’
inferredcites →https://doi.org/10.1016/s0031-9422(03)00113-4openalex-snapshot
Fragrance chemistry, nocturnal rhythms and pollination “syndromes” in Nicotiana
inferredcites →https://doi.org/10.1017/cbo9781139014113.010openalex-snapshot
Why are floral signals complex? An outline of functional hypotheses
inferredcites →https://doi.org/10.1023/a:1024898127549openalex-snapshot
Electroantennographic and Behavioral Responses of the Sphinx Moth Manduca sexta to Host Plant Headspace Volatiles
inferredcites →https://doi.org/10.1023/b:joec.0000030298.77377.7dopenalex-snapshot
Floral CO2 Reveals Flower Profitability to Moths
inferredcites →https://doi.org/10.1038/35069058openalex-snapshot
Caterpillar-induced nocturnal plant volatiles repel conspecific females
inferredcites →https://doi.org/10.1038/nature01065openalex-snapshot
Scotopic colour vision in nocturnal hawkmoths
inferredcites →https://doi.org/10.1038/nature05466openalex-snapshot
Two chemosensory receptors together mediate carbon dioxide detection in Drosophila
inferredcites →https://doi.org/10.1038/nature06850openalex-snapshot
Insect olfactory receptors are heteromeric ligand-gated ion channels
inferredcites →https://doi.org/10.1038/nature06861openalex-snapshot
Drosophila odorant receptors are both ligand-gated and cyclic-nucleotide-activated cation channels
inferredcites →https://doi.org/10.1038/nature12206openalex-snapshot
orco mutant mosquitoes lose strong preference for humans and are not repelled by volatile DEET
inferredcites →https://doi.org/10.1038/ncomms11388openalex-snapshot
Arabidopsis PROTEASOME REGULATOR1 is required for auxin-mediated suppression of proteasome activity and regulates auxin signalling
inferredcites →https://doi.org/10.1038/ncomms11644openalex-snapshot
Innate olfactory preferences for flowers matching proboscis length ensure optimal energy gain in a hawkmoth
inferredcites →https://doi.org/10.1038/s41586-018-0420-8openalex-snapshot
Cryo-EM structure of the insect olfactory receptor Orco
inferredcites →https://doi.org/10.1038/srep29620openalex-snapshot
Heritable genome editing with CRISPR/Cas9 induces anosmia in a crop pest moth
inferredcites →https://doi.org/10.1046/j.1570-7458.2001.00904.xopenalex-snapshot
Influence of visual stimuli on host location in the butterfly, Eurema hecabe
inferredcites →https://doi.org/10.1073/pnas.0709811105openalex-snapshot
Behavioral consequences of innate preferences and olfactory learning in hawkmoth–flower interactions
inferredcites →https://doi.org/10.1073/pnas.0910592106openalex-snapshot
Neural correlates of behavior in the moth Manduca sexta in response to complex odors
inferredcites →https://doi.org/10.1073/pnas.1102425108openalex-snapshot
Functional agonism of insect odorant receptor ion channels
inferredcites →https://doi.org/10.1073/pnas.1121624109openalex-snapshot
Floral humidity as a reliable sensory cue for profitability assessment by nectar-foraging hawkmoths
inferredcites →https://doi.org/10.1073/pnas.91.14.6634openalex-snapshot
Drosophila mode of metamerization in the embryogenesis of the lepidopteran insect Manduca sexta.
inferredcites →https://doi.org/10.1086/337374openalex-snapshot
Behavior of Hawkmoths on Flowers of Datura meteloides
inferredcites →https://doi.org/10.1086/378539openalex-snapshot
Trumpet Flowers of the Sonoran Desert: Floral Biology ofPeniocereusCacti and SacredDatura
inferredcites →https://doi.org/10.1093/aob/mcp053openalex-snapshot
Reproductive biology of Datura wrightii: the benefits of a herbivorous pollinator
inferredcites →https://doi.org/10.1093/chemse/26.9.1175openalex-snapshot
Detection of Sex Pheromone Components in Manduca sexta (L.)
inferredcites →https://doi.org/10.1093/chemse/bjs089openalex-snapshot
Plant Species- and Status-specific Odorant Blends Guide Oviposition Choice in the Moth Manduca sexta
inferredcites →https://doi.org/10.1093/chemse/bju037openalex-snapshot
Physiological Organization and Topographic Mapping of the Antennal Olfactory Sensory Neurons in Female Hawkmoths, Manduca sexta
inferredcites →https://doi.org/10.1093/icb/41.4.825openalex-snapshot
The Costs of Mutualism
inferredcites →https://doi.org/10.1093/icb/icv009openalex-snapshot
Influence of Ambient Illumination on the Use of Olfactory and Visual Signals by a Nocturnal Hawkmoth During Close-Range Foraging
inferredcites →https://doi.org/10.1093/jis/2.1.5openalex-snapshot
Behavioral responses of adult female tobacco hornworms, Manduca sexta, to hostplant volatiles change with age and mating status
inferredcites →https://doi.org/10.1093/jxb/erv219openalex-snapshot
Volatile organic compounds as non-invasive markers for plant phenotyping
inferredcites →https://doi.org/10.1093/nar/gku410openalex-snapshot
CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing
inferredcites →https://doi.org/10.1093/nar/gkw398openalex-snapshot
CHOPCHOP v2: a web tool for the next generation of CRISPR genome engineering
inferredcites →https://doi.org/10.1094/mpmi-22-11-1455openalex-snapshot
Hexanoic Acid-Induced Resistance Against Botrytis cinerea in Tomato Plants
inferredcites →https://doi.org/10.1095/biolreprod.112.105072openalex-snapshot
Sperm Attractant in the Micropyle Region of Fish and Insect Eggs1
inferredcites →https://doi.org/10.1095/biolreprod.112.105312openalex-snapshot
Maternally Recruited DCP1A and DCP2 Contribute to Messenger RNA Degradation During Oocyte Maturation and Genome Activation in Mouse1
inferredcites →https://doi.org/10.1098/rsos.171785openalex-snapshot
Multimodal integration and stimulus categorization in putative mushroom body output neurons of the honeybee
inferredcites →https://doi.org/10.1098/rspb.1981.0066openalex-snapshot
Olfactory interneurons in the moth Manduca sexta : response characteristics and morphology of central neurons in the antennal lobes
inferredcites →https://doi.org/10.1098/rspb.2002.2201openalex-snapshot
Pattern discrimination in a hawkmoth: innate preferences, learning performance and ecology
inferredcites →https://doi.org/10.1111/brv.12043openalex-snapshot
Plant odour plumes as mediators of plant–insect interactions
inferredcites →https://doi.org/10.1111/imb.12246openalex-snapshot
Gustatory receptors in Lepidoptera: chemosensation and beyond
inferredcites →https://doi.org/10.1111/j.1095-8339.1993.tb00340.xopenalex-snapshot
Trends in floral scent chemistry in pollination syndromes: floral scent composition in moth-pollinated taxa
inferredcites →https://doi.org/10.1111/j.1365-2435.2009.01570.xopenalex-snapshot
Field parasitism rates of caterpillars on Brassica oleracea plants are reliably predicted by differential attraction of Cotesia parasitoids
inferredcites →https://doi.org/10.1111/j.1365-3032.1991.tb00588.xopenalex-snapshot
Tarsal contact chemoreceptors of the black swallowtail butterfly Papilio polyxenes: responses to phytochemicals from host‐ and non‐host plants
inferredcites →https://doi.org/10.1111/j.1570-7458.2009.00921.xopenalex-snapshot
Tarsal taste sensilla of the autumn gum moth, Mnesampela privata: morphology and electrophysiological activity
inferredcites →https://doi.org/10.1111/j.1749-6632.2009.03875.xopenalex-snapshot
Neuroethology of Oviposition Behavior in the Moth Manduca sexta
inferredcites →https://doi.org/10.1111/nph.14475openalex-snapshot
Herbivore‐induced plant volatiles and tritrophic interactions across spatial scales
inferredcites →https://doi.org/10.1126/science.1191634openalex-snapshot
Insects Betray Themselves in Nature to Predators by Rapid Isomerization of Green Leaf Volatiles
inferredcites →https://doi.org/10.1126/science.1251041openalex-snapshot
Flower discrimination by pollinators in a dynamic chemical environment
inferredcites →https://doi.org/10.1126/science.139.3558.877openalex-snapshot
Evolutionary Mechanisms in Pollination Biology
inferredcites →https://doi.org/10.1126/science.291.5511.2141openalex-snapshot
Defensive Function of Herbivore-Induced Plant Volatile Emissions in Nature
inferredcites →https://doi.org/10.1146/annurev.en.31.010186.001005openalex-snapshot
Host Odor Perception in Phytophagous Insects
inferredcites →https://doi.org/10.1146/annurev.neuro.30.051606.094306openalex-snapshot
Molecular Architecture of Smell and Taste in Drosophila
inferredcites →https://doi.org/10.1163/157075606777304159openalex-snapshot
Associative learning of visual and gustatory cues in the large cabbage white butterfly, Pieris brassicae
inferredcites →https://doi.org/10.1242/jeb.021220openalex-snapshot
Interaction of visual and odour cues in the mushroom body of the hawkmothManduca sexta
inferredcites →https://doi.org/10.1242/jeb.02169openalex-snapshot
The role of mechanosensory input in flower handling efficiency and learning byManduca sexta
inferredcites →https://doi.org/10.1242/jeb.02752openalex-snapshot
The effect of decoupling olfactory and visual stimuli on the foraging behavior ofManduca sexta
inferredcites →https://doi.org/10.1242/jeb.043760openalex-snapshot
Flight behaviour of the hawkmothManduca sextatowards unimodal and multimodal targets
inferredcites →https://doi.org/10.1242/jeb.047407openalex-snapshot
Flowers help bees cope with uncertainty: signal detection and the function of floral complexity
inferredcites →https://doi.org/10.1242/jeb.143396openalex-snapshot
Intracellular regulation of the insect chemoreceptor complex impacts odor localization in flying insects
inferredcites →https://doi.org/10.1242/jeb.154260openalex-snapshot
Identification and characterization of the bombykal receptor in the hawkmoth Manduca sexta
inferredcites →https://doi.org/10.1242/jeb.202.19.2619openalex-snapshot
Ovipositing butterflies use a red receptor to see green
inferredcites →https://doi.org/10.1242/jeb.64.3.529openalex-snapshot
Flight energetics of sphinx moths: power input during hovering flight
inferredcites →https://doi.org/10.1371/journal.pbio.0040020openalex-snapshot
Atypical Membrane Topology and Heteromeric Function of Drosophila Odorant Receptors In Vivo
inferredcites →https://doi.org/10.1371/journal.pgen.1001064openalex-snapshot
Ancient Protostome Origin of Chemosensory Ionotropic Glutamate Receptors and the Evolution of Insect Taste and Olfaction
inferredcites →https://doi.org/10.1371/journal.pone.0032372openalex-snapshot
Amino Acid Residues Contributing to Function of the Heteromeric Insect Olfactory Receptor Complex
inferredcites →https://doi.org/10.1371/journal.pone.0062648openalex-snapshot
In situ Tip-Recordings Found No Evidence for an Orco-Based Ionotropic Mechanism of Pheromone-Transduction in Manduca sexta
inferredcites →https://doi.org/10.1371/journal.pone.0071137openalex-snapshot
Learning of Multi-Modal Stimuli in Hawkmoths
inferredcites →https://doi.org/10.1371/journal.pone.0072809openalex-snapshot
Multimodal Floral Signals and Moth Foraging Decisions
inferredcites →https://doi.org/10.1371/journal.pone.0166060openalex-snapshot
No Evidence for Ionotropic Pheromone Transduction in the Hawkmoth Manduca sexta
inferredcites →https://doi.org/10.1523/jneurosci.2360-11.2011openalex-snapshot
Complementary Function and Integrated Wiring of the Evolutionarily Distinct Drosophila Olfactory Subsystems
inferredcites →https://doi.org/10.1523/jneurosci.4120-08.2009openalex-snapshot
The Differing Impact of Multisensory and Unisensory Integration on Behavior
inferredcites →https://doi.org/10.3389/fevo.2016.00130openalex-snapshot
Functional Olfactory Sensory Neurons Housed in Olfactory Sensilla on the Ovipositor of the Hawkmoth Manduca sexta
inferredcites →https://doi.org/10.3389/fncel.2014.00261openalex-snapshot
Dimerisation of the Drosophila odorant coreceptor Orco
inferredcites →https://doi.org/10.4161/cib.1.1.6350openalex-snapshot
Floral trait associations in hawkmoth-specialized and mixed pollination systems
inferredcites →https://doi.org/10.7554/elife.00421openalex-snapshot
Feeding-induced rearrangement of green leaf volatiles reduces moth oviposition
inferredcites →https://doi.org/10.7554/elife.03671openalex-snapshot
Quantitative analysis of mammalian GIRK2 channel regulation by G proteins, the signaling lipid PIP2 and Na+ in a reconstituted system
inferredcites →https://doi.org/10.7554/elife.12248openalex-snapshot
RETRACTED: A mathematical model explains saturating axon guidance responses to molecular gradients
inferredcites →https://doi.org/10.7554/elife.15039openalex-snapshot
Hawkmoths evaluate scenting flowers with the tip of their proboscis
inferredcites →https://doi.org/10.7554/elife.20010openalex-snapshot
Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1101/725820openalex-snapshot
The olfactory co-receptor IR8a governs larval-frass mediated competition avoidance in a hawkmoth
inferred← citeshttps://doi.org/10.3389/fphys.2022.924750openalex-snapshot
Insights Into Chemosensory Proteins From Non-Model Insects: Advances and Perspectives in the Context of Pest Management
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