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Sets of Co-regulated Serum Lipids are Associated with Alzheimer Disease Pathophysiology

https://doi.org/10.1101/550723
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Outgoing claims: the papers this work cites, builds on, or argues with.

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Fatty acid analysis of blood plasma of patients with alzheimer's disease, other types of dementia, and cognitive impairment
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Plasmalogen modulation attenuates atherosclerosis in ApoE- and ApoE/GPx1-deficient mice
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Amyloid-β Peptide Induces Mitochondrial Dysfunction by Inhibition of Preprotein Maturation
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Intestinal Phospholipid Remodeling Is Required for Dietary-Lipid Uptake and Survival on a High-Fat Diet
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The Dynamics of Apoptotic Cell Clearance
inferredcites →https://doi.org/10.1016/j.jalz.2010.03.014openalex-snapshot
Plasma ceramides are altered in mild cognitive impairment and predict cognitive decline and hippocampal volume loss
inferredcites →https://doi.org/10.1016/j.jalz.2015.12.008openalex-snapshot
Blood metabolite markers of preclinical Alzheimer's disease in two longitudinally followed cohorts of older individuals
inferredcites →https://doi.org/10.1016/j.jalz.2016.08.003openalex-snapshot
Association of blood lipids with Alzheimer's disease: A comprehensive lipidomics analysis
inferredcites →https://doi.org/10.1016/j.jalz.2017.01.020openalex-snapshot
Metabolic network failures in Alzheimer's disease: A biochemical road map
inferredcites →https://doi.org/10.1016/j.jalz.2017.08.012openalex-snapshot
A systematic integrated analysis of brain expression profiles reveals YAP1 and other prioritized hub genes as important upstream regulators in Alzheimer's disease
inferredcites →https://doi.org/10.1016/j.jalz.2017.11.012openalex-snapshot
Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies
inferredcites →https://doi.org/10.1016/j.neurobiolaging.2008.05.010openalex-snapshot
Deregulation of sphingolipid metabolism in Alzheimer's disease
inferredcites →https://doi.org/10.1016/j.neurobiolaging.2011.12.014openalex-snapshot
Effects of omega-3 fatty acids on cognitive performance: a meta-analysis
inferredcites →https://doi.org/10.1016/j.neurobiolaging.2016.03.005openalex-snapshot
Medium-chain plasma acylcarnitines, ketone levels, cognition, and gray matter volumes in healthy elderly, mildly cognitively impaired, or Alzheimer's disease subjects
inferredcites →https://doi.org/10.1016/j.neurobiolaging.2016.03.028openalex-snapshot
TBK1 is associated with ALS and ALS-FTD in Sardinian patients
inferredcites →https://doi.org/10.1016/s0140-6736(15)01124-1openalex-snapshot
Alzheimer's disease
inferredcites →https://doi.org/10.1021/acs.analchem.7b02380openalex-snapshot
Systems-Level Annotation of a Metabolomics Data Set Reduces 25 000 Features to Fewer than 1000 Unique Metabolites
inferredcites →https://doi.org/10.1038/cdd.2016.25openalex-snapshot
Emerging roles for lipids in non-apoptotic cell death
inferredcites →https://doi.org/10.1038/nature05292openalex-snapshot
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
inferredcites →https://doi.org/10.1038/nm.3466openalex-snapshot
Plasma phospholipids identify antecedent memory impairment in older adults
inferredcites →https://doi.org/10.1038/nmeth.2551openalex-snapshot
LipidBlast in silico tandem mass spectrometry database for lipid identification
inferredcites →https://doi.org/10.1038/nrm.2017.66openalex-snapshot
Mitochondrial diseases: the contribution of organelle stress responses to pathology
inferredcites →https://doi.org/10.1038/nrneurol.2012.263openalex-snapshot
Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy
inferredcites →https://doi.org/10.1038/s41598-017-15231-wopenalex-snapshot
Chemical Similarity Enrichment Analysis (ChemRICH) as alternative to biochemical pathway mapping for metabolomic datasets
inferredcites →https://doi.org/10.1038/sdata.2018.263openalex-snapshot
Generation and quality control of lipidomics data for the alzheimer’s disease neuroimaging initiative cohort
inferredcites →https://doi.org/10.1038/tp.2014.127openalex-snapshot
Plasma lipidomics analysis finds long chain cholesteryl esters to be associated with Alzheimer’s disease
inferredcites →https://doi.org/10.1038/tp.2017.118openalex-snapshot
Metabolomics and cognition in African American adults in midlife: the atherosclerosis risk in communities study
inferredcites →https://doi.org/10.1046/j.1471-4159.2002.00997.xopenalex-snapshot
Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: potential role in disease pathogenesis
inferredcites →https://doi.org/10.1073/pnas.0305799101openalex-snapshot
Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease
inferredcites →https://doi.org/10.1073/pnas.86.8.2903openalex-snapshot
Membrane docosahexaenoate is supplied to the developing brain and retina by the liver.
inferredcites →https://doi.org/10.1089/ars.2012.4875openalex-snapshot
Mitochondrial Fatty Acid Oxidation in Obesity
inferredcites →https://doi.org/10.1093/bioinformatics/btm563openalex-snapshot
Defining clusters from a hierarchical cluster tree: the Dynamic Tree Cut package for R
inferredcites →https://doi.org/10.1093/bioinformatics/btq418openalex-snapshot
MetPA: a web-based metabolomics tool for pathway analysis and visualization
inferredcites →https://doi.org/10.1139/jpn.090059openalex-snapshot
Circulating plasmalogen levels and Alzheimer Disease Assessment Scale–Cognitive scores in Alzheimer patients
inferredcites →https://doi.org/10.1194/jlr.m079012openalex-snapshot
Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950–Metabolites in Frozen Human Plasma
inferredcites →https://doi.org/10.1212/wnl.0b013e318264e380openalex-snapshot
Serum ceramides increase the risk of Alzheimer disease
inferredcites →https://doi.org/10.1371/journal.pmed.1002265openalex-snapshot
Differential associations of plasma lipids with incident dementia and dementia subtypes in the 3C Study: A longitudinal, population-based prospective cohort study
inferredcites →https://doi.org/10.1371/journal.pmed.1002482openalex-snapshot
Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study
inferredcites →https://doi.org/10.1371/journal.pone.0021643openalex-snapshot
Metabolomics in Early Alzheimer's Disease: Identification of Altered Plasma Sphingolipidome Using Shotgun Lipidomics
inferredcites →https://doi.org/10.1371/journal.pone.0055531openalex-snapshot
Relationship between Plasma Analytes and SPARE-AD Defined Brain Atrophy Patterns in ADNI
inferredcites →https://doi.org/10.1371/journal.pone.0203659openalex-snapshot
Impaired hepatic amyloid-beta degradation in Alzheimer’s disease
inferredcites →https://doi.org/10.3233/jad-122224openalex-snapshot
Plasma Fatty Acid Lipidomics in Amnestic Mild Cognitive Impairment and Alzheimer's Disease
inferredcites →https://doi.org/10.3233/jad-2010-1242openalex-snapshot
Lipid Alterations in Lipid Rafts from Alzheimer's Disease Human Brain Cortex
inferredcites →https://doi.org/10.3233/jad-2012-110629openalex-snapshot
Plasma and Brain Fatty Acid Profiles in Mild Cognitive Impairment and Alzheimer's Disease
inferredcites →https://doi.org/10.3389/fnagi.2015.00052openalex-snapshot
Long-chain omega-3 fatty acids and the brain: a review of the independent and shared effects of EPA, DPA and DHA
inferredcites →https://doi.org/10.3389/fneur.2015.00237openalex-snapshot
Plasma 24-metabolite Panel Predicts Preclinical Transition to Clinical Stages of Alzheimer’s Disease
inferredcites →https://doi.org/10.3945/jn.108.103754openalex-snapshot
Plasma Acylcarnitine Profiles Suggest Incomplete Long-Chain Fatty Acid β-Oxidation and Altered Tricarboxylic Acid Cycle Activity in Type 2 Diabetic African-American Women
inferredcites →https://doi.org/10.7554/elife.06328openalex-snapshot
Fatty acid remodeling by LPCAT3 enriches arachidonate in phospholipid membranes and regulates triglyceride transport
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