On the public citation graph

Estimation of Non-null SNP Effect Size Distributions Enables the Detection of Enriched Genes Underlying Complex Traits

0 signed · 106 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.

Claim with ORCID

Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.

See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/0471721182openalex-snapshot

Finite Mixture Models

inferredcites →https://doi.org/10.1002/ajmg.a.36587openalex-snapshot

New candidate loci identified by array‐CGH in a cohort of 100 children presenting with syndromic obesity

inferredcites →https://doi.org/10.1002/gepi.22098openalex-snapshot

Gene‐based genetic association test with adaptive optimal weights

inferredcites →https://doi.org/10.1016/j.ajhg.2010.05.002openalex-snapshot

Powerful SNP-Set Analysis for Case-Control Genome-wide Association Studies

inferredcites →https://doi.org/10.1016/j.ajhg.2010.06.009openalex-snapshot

A Versatile Gene-Based Test for Genome-wide Association Studies

inferredcites →https://doi.org/10.1016/j.ajhg.2011.02.002openalex-snapshot

Estimating Missing Heritability for Disease from Genome-wide Association Studies

inferredcites →https://doi.org/10.1016/j.ajhg.2011.05.029openalex-snapshot

Rare-Variant Association Testing for Sequencing Data with the Sequence Kernel Association Test

inferredcites →https://doi.org/10.1016/j.ajhg.2011.11.018openalex-snapshot

Mutations in EZH2 Cause Weaver Syndrome

inferredcites →https://doi.org/10.1016/j.ajhg.2011.11.029openalex-snapshot

Five Years of GWAS Discovery

inferredcites →https://doi.org/10.1016/j.ajhg.2012.06.007openalex-snapshot

Optimal Unified Approach for Rare-Variant Association Testing with Application to Small-Sample Case-Control Whole-Exome Sequencing Studies

inferredcites →https://doi.org/10.1016/j.ajhg.2013.04.015openalex-snapshot

Sequence Kernel Association Tests for the Combined Effect of Rare and Common Variants

inferredcites →https://doi.org/10.1016/j.ajhg.2013.08.012openalex-snapshot

Fine Mapping and Identification of BMI Loci in African Americans

inferredcites →https://doi.org/10.1016/j.ajhg.2014.06.009openalex-snapshot

Rare-Variant Association Analysis: Study Designs and Statistical Tests

inferredcites →https://doi.org/10.1016/j.ajhg.2016.05.005openalex-snapshot

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

inferredcites →https://doi.org/10.1016/j.ajhg.2016.05.013openalex-snapshot

Contrasting the Genetic Architecture of 30 Complex Traits from Summary Association Data

inferredcites →https://doi.org/10.1016/j.ajhg.2016.10.003openalex-snapshot

Colocalization of GWAS and eQTL Signals Detects Target Genes

inferredcites →https://doi.org/10.1016/j.cell.2016.10.042openalex-snapshot

The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease

inferredcites →https://doi.org/10.1016/j.cell.2017.05.038openalex-snapshot

An Expanded View of Complex Traits: From Polygenic to Omnigenic

inferredcites →https://doi.org/10.1016/j.cell.2018.05.051openalex-snapshot

Common Disease Is More Complex Than Implied by the Core Gene Omnigenic Model

inferredcites →https://doi.org/10.1016/j.csda.2009.11.025openalex-snapshot

Computing the distribution of quadratic forms: Further comparisons between the Liu–Tang–Zhang approximation and exact methods

inferredcites →https://doi.org/10.1038/nature08494openalex-snapshot

Finding the missing heritability of complex diseases

inferredcites →https://doi.org/10.1038/nature13138openalex-snapshot

Obesity-associated variants within FTO form long-range functional connections with IRX3

inferredcites →https://doi.org/10.1038/nature14177openalex-snapshot

Genetic studies of body mass index yield new insights for obesity biology

inferredcites →https://doi.org/10.1038/nature14248openalex-snapshot

Integrative analysis of 111 reference human epigenomes

inferredcites →https://doi.org/10.1038/nature19356openalex-snapshot

High-throughput discovery of novel developmental phenotypes

inferredcites →https://doi.org/10.1038/nature21039openalex-snapshot

Rare and low-frequency coding variants alter human adult height

inferredcites →https://doi.org/10.1038/nature24277openalex-snapshot

Genetic effects on gene expression across human tissues

inferredcites →https://doi.org/10.1038/nature25973openalex-snapshot

Environment dominates over host genetics in shaping human gut microbiota

inferredcites →https://doi.org/10.1038/ng.130openalex-snapshot

Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)

inferredcites →https://doi.org/10.1038/ng.2876openalex-snapshot

Advantages and pitfalls in the application of mixed-model association methods

inferredcites →https://doi.org/10.1038/ng.3097openalex-snapshot

Defining the role of common variation in the genomic and biological architecture of adult human height

inferredcites →https://doi.org/10.1038/ng.3211openalex-snapshot

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

inferredcites →https://doi.org/10.1038/ng.3390openalex-snapshot

Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index

inferredcites →https://doi.org/10.1038/ng.3668openalex-snapshot

Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps

inferredcites →https://doi.org/10.1038/ng.3865openalex-snapshot

Reevaluation of SNP heritability in complex human traits

inferredcites →https://doi.org/10.1038/ng.3912openalex-snapshot

Genotype–covariate interaction effects and the heritability of adult body mass index

inferredcites →https://doi.org/10.1038/ng.456openalex-snapshot

Common variants in TMPRSS6 are associated with iron status and erythrocyte volume

inferredcites →https://doi.org/10.1038/ng.462openalex-snapshot

Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels

inferredcites →https://doi.org/10.1038/ng.466openalex-snapshot

Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium

inferredcites →https://doi.org/10.1038/ng.467openalex-snapshot

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

inferredcites →https://doi.org/10.1038/ng.608openalex-snapshot

Common SNPs explain a large proportion of the heritability for human height

inferredcites →https://doi.org/10.1038/ng1109-1161openalex-snapshot

Genes determining blood cell traits

inferredcites →https://doi.org/10.1038/nmeth.3285openalex-snapshot

Accurate liability estimation improves power in ascertained case-control studies

inferredcites →https://doi.org/10.1038/nrg2322openalex-snapshot

Heritability in the genomics era — concepts and misconceptions

inferredcites →https://doi.org/10.1038/s41467-017-00470-2openalex-snapshot

Non-parametric genetic prediction of complex traits with latent Dirichlet process regression models

inferredcites →https://doi.org/10.1038/s41467-018-03371-0openalex-snapshot

Integrative analysis of omics summary data reveals putative mechanisms underlying complex traits

inferredcites →https://doi.org/10.1038/s41467-018-04951-wopenalex-snapshot

Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes

inferredcites →https://doi.org/10.1038/s41467-018-06805-xopenalex-snapshot

Large-scale genome-wide enrichment analyses identify new trait-associated genes and pathways across 31 human phenotypes

inferredcites →https://doi.org/10.1038/s41467-019-12653-0openalex-snapshot

Improved polygenic prediction by Bayesian multiple regression on summary statistics

inferredcites →https://doi.org/10.1038/s41586-018-0579-zopenalex-snapshot

The UK Biobank resource with deep phenotyping and genomic data

inferredcites →https://doi.org/10.1038/s41588-018-0193-xopenalex-snapshot

Estimation of complex effect-size distributions using summary-level statistics from genome-wide association studies across 32 complex traits

inferredcites →https://doi.org/10.1038/s41588-018-0231-8openalex-snapshot

Functional architecture of low-frequency variants highlights strength of negative selection across coding and non-coding annotations

inferredcites →https://doi.org/10.1038/s41588-019-0379-xopenalex-snapshot

Clinical use of current polygenic risk scores may exacerbate health disparities

inferredcites →https://doi.org/10.1056/nejmoa1502214openalex-snapshot

FTO Obesity Variant Circuitry and Adipocyte Browning in Humans

inferredcites →https://doi.org/10.1056/nejmp0806284openalex-snapshot

Common Genetic Variation and Human Traits

inferredcites →https://doi.org/10.1073/pnas.0906268106openalex-snapshot

Canonical Wnt signaling negatively regulates platelet function

inferredcites →https://doi.org/10.1073/pnas.1322563111openalex-snapshot

Searching for missing heritability: Designing rare variant association studies

inferredcites →https://doi.org/10.1073/pnas.1419064111openalex-snapshot

Measuring missing heritability: Inferring the contribution of common variants

inferredcites →https://doi.org/10.1073/pnas.1510497113openalex-snapshot

Linear mixed model for heritability estimation that explicitly addresses environmental variation

inferredcites →https://doi.org/10.1073/pnas.1614893114openalex-snapshot

DYRK1A regulates Hap1–Dcaf7/WDR68 binding with implication for delayed growth in Down syndrome

inferredcites →https://doi.org/10.1073/pnas.96.17.9648openalex-snapshot

Wiskott-Aldrich syndrome protein regulates podosomes in primary human macrophages

inferredcites →https://doi.org/10.1093/biomet/48.3-4.419openalex-snapshot

Computing the Distribution of Quadratic Forms in Normal Variables

inferredcites →https://doi.org/10.1093/biomet/asq017openalex-snapshot

The horseshoe estimator for sparse signals

inferredcites →https://doi.org/10.1093/biostatistics/kxw041openalex-snapshot

False discovery rates: a new deal

inferredcites →https://doi.org/10.1093/database/baq020openalex-snapshot

GeneCards Version 3: the human gene integrator

inferredcites →https://doi.org/10.1093/hmg/dds534openalex-snapshot

GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children

inferredcites →https://doi.org/10.1093/humupd/dmh012openalex-snapshot

Precocious puberty and statural growth

inferredcites →https://doi.org/10.1093/nar/gki476openalex-snapshot

PupasView: a visual tool for selecting suitable SNPs, with putative pathological effect in genes, for genotyping purposes

inferredcites →https://doi.org/10.1093/nar/gkl1003openalex-snapshot

The mouse Gene Expression Database (GXD): 2007 update

inferredcites →https://doi.org/10.1093/nar/gkq1224openalex-snapshot

TEFM (c17orf42) is necessary for transcription of human mtDNA

inferredcites →https://doi.org/10.1093/nar/gku987openalex-snapshot

Mouse Tumor Biology (MTB): a database of mouse models for human cancer

inferredcites →https://doi.org/10.1093/nar/gkw377openalex-snapshot

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

inferredcites →https://doi.org/10.1093/nar/gkx1006openalex-snapshot

Mouse Genome Database (MGD)-2018: knowledgebase for the laboratory mouse

inferredcites →https://doi.org/10.1111/j.1467-9868.2005.00503.xopenalex-snapshot

Regularization and Variable Selection Via the Elastic Net

inferredcites →https://doi.org/10.1111/j.2517-6161.1977.tb01600.xopenalex-snapshot

Maximum Likelihood from Incomplete Data Via the EM Algorithm

inferredcites →https://doi.org/10.1111/j.2517-6161.1996.tb02080.xopenalex-snapshot

Regression Shrinkage and Selection Via the Lasso

inferredcites →https://doi.org/10.1137/0905052openalex-snapshot

The Collinearity Problem in Linear Regression. The Partial Least Squares (PLS) Approach to Generalized Inverses

inferredcites →https://doi.org/10.1159/000353591openalex-snapshot

TFAP2B-Dietary Protein and Glycemic Index Interactions and Weight Maintenance after Weight Loss in the DiOGenes Trial

inferredcites →https://doi.org/10.1182/blood-2012-03-416875openalex-snapshot

Canonical Wnt signaling in megakaryocytes regulates proplatelet formation

inferredcites →https://doi.org/10.1182/blood-2016-03-378588openalex-snapshot

Inherited platelet disorders: toward DNA-based diagnosis

inferredcites →https://doi.org/10.1186/1471-2105-14-128openalex-snapshot

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

inferredcites →https://doi.org/10.1214/009053604000000238openalex-snapshot

Optimal predictive model selection

inferredcites →https://doi.org/10.1214/17-aoas1046openalex-snapshot

Bayesian large-scale multiple regression with summary statistics from genome-wide association studies

inferredcites →https://doi.org/10.1214/17-aoas1052openalex-snapshot

A unified framework for variance component estimation with summary statistics in genome-wide association studies

inferredcites →https://doi.org/10.1214/aos/1176344136openalex-snapshot

Estimating the Dimension of a Model

inferredcites →https://doi.org/10.1371/journal.pcbi.1004219openalex-snapshot

MAGMA: Generalized Gene-Set Analysis of GWAS Data

inferredcites →https://doi.org/10.1371/journal.pcbi.1004714openalex-snapshot

Fast and Rigorous Computation of Gene and Pathway Scores from SNP-Based Summary Statistics

inferredcites →https://doi.org/10.1371/journal.pgen.1002491openalex-snapshot

A Meta-Analysis and Genome-Wide Association Study of Platelet Count and Mean Platelet Volume in African Americans

inferredcites →https://doi.org/10.1371/journal.pgen.1002637openalex-snapshot

Heritability and Genetic Correlations Explained by Common SNPs for Metabolic Syndrome Traits

inferredcites →https://doi.org/10.1371/journal.pgen.1003264openalex-snapshot

Polygenic Modeling with Bayesian Sparse Linear Mixed Models

inferredcites →https://doi.org/10.1371/journal.pgen.1003770openalex-snapshot

Integrated Enrichment Analysis of Variants and Pathways in Genome-Wide Association Studies Indicates Central Role for IL-2 Signaling Genes in Type 1 Diabetes, and Cytokine Signaling Genes in Crohn's Disease

inferredcites →https://doi.org/10.1371/journal.pgen.1005804openalex-snapshot

Pedigree- and SNP-Associated Genetics and Recent Environment are the Major Contributors to Anthropometric and Cardiometabolic Trait Variation

inferredcites →https://doi.org/10.1371/journal.pgen.1006711openalex-snapshot

Phenome-wide heritability analysis of the UK Biobank

inferredcites →https://doi.org/10.1371/journal.pgen.1006869openalex-snapshot

Detecting epistasis with the marginal epistasis test in genetic mapping studies of quantitative traits

inferredcites →https://doi.org/10.1371/journal.pgen.1006925openalex-snapshot

Rare coding variants pinpoint genes that control human hematological traits

inferredcites →https://doi.org/10.1371/journal.pgen.1007222openalex-snapshot

A high throughput, functional screen of human Body Mass Index GWAS loci using tissue-specific RNAi Drosophila melanogaster crosses

inferredcites →https://doi.org/10.1371/journal.pmed.1002383openalex-snapshot

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis

inferredcites →https://doi.org/10.1534/genetics.114.167908openalex-snapshot

Identifying Causal Variants at Loci with Multiple Signals of Association

inferredcites →https://doi.org/10.1534/genetics.116.188391openalex-snapshot

Gene and Network Analysis of Common Variants Reveals Novel Associations in Multiple Complex Diseases

inferredcites →https://doi.org/10.1534/genetics.117.300257openalex-snapshot

COMBAT: A Combined Association Test for Genes Using Summary Statistics

inferredcites →https://doi.org/10.1534/genetics.117.300287openalex-snapshot

A Powerful Variant-Set Association Test Based on Chi-Square Distribution

inferredcites →https://doi.org/10.1534/genetics.118.301267openalex-snapshot

Accurate Genomic Prediction of Human Height

inferredcites →https://doi.org/10.18637/jss.v032.i06openalex-snapshot

mixtools : An R Package for Analyzing Finite Mixture Models

inferredcites →https://doi.org/10.2307/1267351openalex-snapshot

Ridge Regression: Biased Estimation for Nonorthogonal Problems

inferredcites →https://doi.org/10.3389/fgene.2016.00015openalex-snapshot

Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1016/j.ajhg.2022.03.005openalex-snapshot

Enrichment analyses identify shared associations for 25 quantitative traits in over 600,000 individuals from seven diverse ancestries

Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.