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The coordination of spindle-positioning forces during the asymmetric division of the C. elegans zygote is revealed by distinct microtubule dynamics at the cortex
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Outgoing claims: the papers this work cites, builds on, or argues with.
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Forces positioning the mitotic spindle: Theories, and now experiments
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Physical Limits on the Precision of Mitotic Spindle Positioning by Microtubule Pushing forces
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An Introduction to the Bootstrap
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A fallacy in the interpretation of fluorescence decay parameters
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[2] Global analysis of biochemical and biophysical data
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A Quantitative Method for Measuring Phototoxicity of a Live Cell Imaging Microscope
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Analysis of Kinetic Intermediates in Single-Particle Dwell-Time Distributions
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The Mitotic Spindle in the One-Cell C . elegans Embryo Is Positioned with High Precision and Stability
inferredcites →https://doi.org/10.1016/j.bpj.2018.10.010openalex-snapshot
Microtubule Feedback and LET-99-Dependent Control of Pulling Forces Ensure Robust Spindle Position
inferredcites →https://doi.org/10.1016/j.ceb.2004.12.011openalex-snapshot
Force generation by dynamic microtubules
inferredcites →https://doi.org/10.1016/j.cell.2004.09.026openalex-snapshot
RIC-8 Is Required for GPR-1/2-Dependent Gα Function during Asymmetric Division of C. elegans Embryos
inferredcites →https://doi.org/10.1016/j.cell.2007.03.027openalex-snapshot
Cortical Microtubule Contacts Position the Spindle in C. elegans Embryos
inferredcites →https://doi.org/10.1016/j.cell.2007.11.043openalex-snapshot
XMAP215 Is a Processive Microtubule Polymerase
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Cortical Dynein Controls Microtubule Dynamics to Generate Pulling Forces that Position Microtubule Asters
inferredcites →https://doi.org/10.1016/j.cub.2004.06.029openalex-snapshot
Positioning and Elongation of the Fission Yeast Spindle by Microtubule-Based Pushing
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The CENP-F-like Proteins HCP-1 and HCP-2 Target CLASP to Kinetochores to Mediate Chromosome Segregation
inferredcites →https://doi.org/10.1016/j.cub.2006.09.030openalex-snapshot
Spindle Oscillations during Asymmetric Cell Division Require a Threshold Number of Active Cortical Force Generators
inferredcites →https://doi.org/10.1016/j.cub.2012.02.023openalex-snapshot
Dynein Tethers and Stabilizes Dynamic Microtubule Plus Ends
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Computer Simulations and Image Processing Reveal Length-Dependent Pulling Force as the Primary Mechanism for C. elegans Male Pronuclear Migration
inferredcites →https://doi.org/10.1016/j.devcel.2005.03.014openalex-snapshot
Spindle Positioning by Cortical Pulling Forces
inferredcites →https://doi.org/10.1016/j.devcel.2005.07.003openalex-snapshot
Identification and Characterization of Factors Required for Microtubule Growth and Nucleation in the Early C. elegans Embryo
inferredcites →https://doi.org/10.1016/j.devcel.2006.03.001openalex-snapshot
Two Phases of Astral Microtubule Activity during Cytokinesis in C. elegans Embryos
inferredcites →https://doi.org/10.1016/j.devcel.2008.06.002openalex-snapshot
A Casein Kinase 1 and PAR Proteins Regulate Asymmetry of a PIP2 Synthesis Enzyme for Asymmetric Spindle Positioning
inferredcites →https://doi.org/10.1016/j.devcel.2011.06.012openalex-snapshot
Mitotic Spindle Orientation in Asymmetric and Symmetric Cell Divisions during Animal Development
inferredcites →https://doi.org/10.1016/j.devcel.2018.04.022openalex-snapshot
Microtubule Dynamics Scale with Cell Size to Set Spindle Length and Assembly Timing
inferredcites →https://doi.org/10.1016/j.devcel.2018.08.023openalex-snapshot
The Structure and Dynamics of C. elegans Tubulin Reveals the Mechanistic Basis of Microtubule Growth
inferredcites →https://doi.org/10.1016/j.ydbio.2007.11.037openalex-snapshot
Dynamic localization of LIN-5 and GPR-1/2 to cortical force generation domains during spindle positioning
inferredcites →https://doi.org/10.1016/j.ydbio.2012.05.016openalex-snapshot
CLASPs function redundantly to regulate astral microtubules in the C. elegans embryo
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Metadata management for high content screening in OMERO
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Application of the Stretched Exponential Function to Fluorescence Lifetime Imaging
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Control of cell polarity and mitotic spindle positioning in animal cells
inferredcites →https://doi.org/10.1016/s0960-9822(03)00251-3openalex-snapshot
PAR Proteins Regulate Microtubule Dynamics at the Cell Cortex in C. elegans
inferredcites →https://doi.org/10.1016/s0960-9822(03)00371-3openalex-snapshot
Asymmetrically Distributed C. elegans Homologs of AGS3/PINS Control Spindle Position in the Early Embryo
inferredcites →https://doi.org/10.1016/s0960-9822(03)00582-7openalex-snapshot
TAC-1 and ZYG-9 Form a Complex that Promotes Microtubule Assembly in C. elegans Embryos
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Caenorhabditis elegans TAC-1 and ZYG-9 Form a Complex that Is Essential for Long Astral and Spindle Microtubules
inferredcites →https://doi.org/10.1016/s1046-2023(03)00050-1openalex-snapshot
Genome-wide RNAi screening in Caenorhabditis elegans
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An Experimental Comparison of the Maximum Likelihood Estimation and Nonlinear Least-Squares Fluorescence Lifetime Analysis of Single Molecules
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Accurate Analysis of Fluorescence Decays from Single Molecules in Photon Counting Experiments
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Dynamic instability of microtubule growth
inferredcites →https://doi.org/10.1038/35054572openalex-snapshot
Polarity controls forces governing asymmetric spindle positioning in the Caenorhabditis elegans embryo
inferredcites →https://doi.org/10.1038/35060092openalex-snapshot
Distinct roles for Gα and Gβγ in regulating spindle position and orientation in Caenorhabditis elegans embryos
inferredcites →https://doi.org/10.1038/nature04132openalex-snapshot
Force production by disassembling microtubules
inferredcites →https://doi.org/10.1038/nature06386openalex-snapshot
Reconstitution of a microtubule plus-end tracking system in vitro
inferredcites →https://doi.org/10.1038/ncb1649openalex-snapshot
Coupling of cortical dynein and Gα proteins mediates spindle positioning in Caenorhabditis elegans
inferredcites →https://doi.org/10.1038/ncb1834openalex-snapshot
NuMA-related LIN-5, ASPM-1, calmodulin and dynein promote meiotic spindle rotation independently of cortical LIN-5/GPR/Gα
inferredcites →https://doi.org/10.1038/ncb2128openalex-snapshot
Caenorhabditis elegans EFA-6 limits microtubule growth at the cell cortex
inferredcites →https://doi.org/10.1038/ncb3150openalex-snapshot
Kinetochore components are required for central spindle assembly
inferredcites →https://doi.org/10.1038/ncb3481openalex-snapshot
Tubulin acetylation protects long-lived microtubules against mechanical ageing
inferredcites →https://doi.org/10.1038/ncomms15063openalex-snapshot
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inferredcites →https://doi.org/10.1038/ncomms15288openalex-snapshot
C. elegans chromosomes connect to centrosomes by anchoring into the spindle network
inferredcites →https://doi.org/10.1038/nmeth.1237openalex-snapshot
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inferredcites →https://doi.org/10.1038/nmeth.2808openalex-snapshot
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inferredcites →https://doi.org/10.1038/nmeth0510-338openalex-snapshot
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inferredcites →https://doi.org/10.1038/nrm2388openalex-snapshot
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inferredcites →https://doi.org/10.1038/s41567-019-0542-4openalex-snapshot
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inferredcites →https://doi.org/10.1051/medsci/20031967725openalex-snapshot
C. elegans : des neurones et des gènes
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inferredcites →https://doi.org/10.1073/pnas.1013275108openalex-snapshot
Intracellular organelles mediate cytoplasmic pulling force for centrosome centration in the Caenorhabditis elegans early embryo
inferredcites →https://doi.org/10.1073/pnas.1017369108openalex-snapshot
A model of cytoplasmically driven microtubule-based motion in the single-celled Caenorhabditis elegans embryo
inferredcites →https://doi.org/10.1073/pnas.1712052115openalex-snapshot
Tumor suppressor APC is an attenuator of spindle-pulling forces during C. elegans asymmetric cell division
inferredcites →https://doi.org/10.1073/pnas.252407099openalex-snapshot
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Dynein Interacts with the Neural Cell Adhesion Molecule (NCAM180) to Tether Dynamic Microtubules and Maintain Synaptic Density in Cortical Neurons
inferredcites →https://doi.org/10.1083/jcb.147.1.135openalex-snapshot
Cytoplasmic Dynein Is Required for Distinct Aspects of Mtoc Positioning, Including Centrosome Separation, in the One Cell Stage Caenorhabditis elegans Embryo
inferredcites →https://doi.org/10.1083/jcb.153.2.397openalex-snapshot
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inferredcites →https://doi.org/10.1083/jcb.200210171openalex-snapshot
Myosin and the PAR proteins polarize microfilament-dependent forces that shape and position mitotic spindles in Caenorhabditis elegans
inferredcites →https://doi.org/10.1083/jcb.200301147openalex-snapshot
Dynamic instability of microtubules is regulated by force
inferredcites →https://doi.org/10.1083/jcb.200406008openalex-snapshot
The forces that position a mitotic spindle asymmetrically are tethered until after the time of spindle assembly
inferredcites →https://doi.org/10.1083/jcb.200706005openalex-snapshot
Local cortical pulling-force repression switches centrosomal centration and posterior displacement in C. elegans
inferredcites →https://doi.org/10.1083/jcb.200707085openalex-snapshot
Heterotrimeric G protein signaling functions with dynein to promote spindle positioning in C. elegans
inferredcites →https://doi.org/10.1083/jcb.201001115openalex-snapshot
LET-99 inhibits lateral posterior pulling forces during asymmetric spindle elongation in C. elegans embryos
inferredcites →https://doi.org/10.1083/jcb.201103128openalex-snapshot
Visualization of dynein-dependent microtubule gliding at the cell cortex: implications for spindle positioning
inferredcites →https://doi.org/10.1083/jcb.201210007openalex-snapshot
Mechanisms of spindle positioning
inferredcites →https://doi.org/10.1083/jcb.201210110openalex-snapshot
Evolutionary comparisons reveal a positional switch for spindle pole oscillations in Caenorhabditis embryos
inferredcites →https://doi.org/10.1083/jcb.201412035openalex-snapshot
Kinetochore-localized BUB-1/BUB-3 complex promotes anaphase onset in C. elegans
inferredcites →https://doi.org/10.1083/jcb.201607038openalex-snapshot
Two populations of cytoplasmic dynein contribute to spindle positioning in C. elegans embryos
inferredcites →https://doi.org/10.1083/jcb.201807102openalex-snapshot
Asymmetric division through a reduction of microtubule centering forces
inferredcites →https://doi.org/10.1086/499065openalex-snapshot
Statistical Evidence: A Likelihood Paradigm
inferredcites →https://doi.org/10.1088/0031-9155/50/6/019openalex-snapshot
Artefacts in the analysis of temporal response functions measured by photon counting
inferredcites →https://doi.org/10.1088/1367-2630/14/10/105025openalex-snapshot
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inferredcites →https://doi.org/10.1088/1478-3975/3/1/006openalex-snapshot
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inferredcites →https://doi.org/10.1088/1478-3975/3/1/s06openalex-snapshot
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inferredcites →https://doi.org/10.1091/mbc.e03-01-0017openalex-snapshot
Mutations in a β-Tubulin Disrupt Spindle Orientation and Microtubule Dynamics in the Early Caenorhabditis elegans Embryo
inferredcites →https://doi.org/10.1091/mbc.e04-06-0523openalex-snapshot
Functional Analysis of Cytoplasmic Dynein Heavy Chain inCaenorhabditis eleganswith Fast-acting Temperature-sensitive Mutations
inferredcites →https://doi.org/10.1091/mbc.e07-02-0105openalex-snapshot
PAR-3 and PAR-1 Inhibit LET-99 Localization to Generate a Cortical Band Important for Spindle Positioning inCaenorhabditis elegansEmbryos
inferredcites →https://doi.org/10.1091/mbc.e10-07-0627openalex-snapshot
Finding the Cell Center by a Balance of Dynein and Myosin Pulling and Microtubule Pushing: A Computational Study
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inferredcites →https://doi.org/10.1091/mbc.e17-11-0653openalex-snapshot
The polarity-induced force imbalance inCaenorhabditis elegansembryos is caused by asymmetric binding rates of dynein to the cortex
inferredcites →https://doi.org/10.1093/genetics/157.3.1217openalex-snapshot
Creation of Low-Copy Integrated Transgenic Lines in Caenorhabditis elegans
inferredcites →https://doi.org/10.1093/genetics/77.1.71openalex-snapshot
THE GENETICS OF CAENORHABDITIS ELEGANS
inferredcites →https://doi.org/10.1101/gad.1081203openalex-snapshot
A complex of LIN-5 and GPR proteins regulates G protein signaling and spindle function in C. elegans
inferredcites →https://doi.org/10.1101/gad.1850809openalex-snapshot
Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer
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Biophysical Active Contours for Cell Tracking I: Tension and Bending
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Adaptive Spot Detection With Optimal Scale Selection in Fluorescence Microscopy Images
inferredcites →https://doi.org/10.1109/tmi.2009.2033991openalex-snapshot
Patch-Based Nonlocal Functional for Denoising Fluorescence Microscopy Image Sequences
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Multiple Hypothesis Tracking for Cluttered Biological Image Sequences
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A New Approach to Linear Filtering and Prediction Problems
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Application of the stretched exponential function to fluorescence lifetime imaging of biological tissue
inferredcites →https://doi.org/10.1126/science.1084146openalex-snapshot
Translation of Polarity Cues into Asymmetric Spindle Positioning in Caenorhabditis elegans Embryos
inferredcites →https://doi.org/10.1126/science.1086560openalex-snapshot
The Distribution of Active Force Generators Controls Mitotic Spindle Position
inferredcites →https://doi.org/10.1126/science.1219147openalex-snapshot
Growing Microtubules Push the Oocyte Nucleus to Polarize the Drosophila Dorsal-Ventral Axis
inferredcites →https://doi.org/10.1126/science.aad9745openalex-snapshot
A force-generating machinery maintains the spindle at the cell center during mitosis
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An Introduction to the Bootstrap
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Estimating the Dimension of a Model
inferredcites →https://doi.org/10.1242/dev.00790openalex-snapshot
LET-99 opposes Gα/GPR signaling to generate asymmetry for spindle positioning in response to PAR and MES-1/SRC-1 signaling
inferredcites →https://doi.org/10.1242/dev.02039openalex-snapshot
Cortical localization of the Gα protein GPA-16 requires RIC-8 function duringC. elegansasymmetric cell division
inferredcites →https://doi.org/10.1242/dev.129.19.4469openalex-snapshot
LET-99 determines spindle position and is asymmetrically enriched in response to PAR polarity cues inC. elegansembryos
inferredcites →https://doi.org/10.1242/dev.147504openalex-snapshot
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inferredcites →https://doi.org/10.1242/jcs.200923openalex-snapshot
Tubulin isotype substitution revealed that isotype combination modulates microtubule dynamics in C. elegans embryos
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inferredcites →https://doi.org/10.1371/journal.pone.0007585openalex-snapshot
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inferredcites →https://doi.org/10.1371/journal.pone.0012301openalex-snapshot
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inferredcites →https://doi.org/10.1371/journal.pone.0035286openalex-snapshot
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inferredcites →https://doi.org/10.4161/cc.21753openalex-snapshot
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inferredcites →https://doi.org/10.4161/cc.8.8.8150openalex-snapshot
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The size of the EB cap determines instantaneous microtubule stability
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Neurexin directs partner-specific synaptic connectivity in C. elegans
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Optogenetic dissection of mitotic spindle positioning in vivo
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