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Cellular reprogramming for successful CNS axon regeneration is driven by a temporally changing cast of transcription factors

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/(sici)1096-9861(19961209)376:2<253::aid-cne7>3.0.co;2-2openalex-snapshot
Increased expression of specific recognition molecules by retinal ganglion cells and by optic pathway glia accompanies the successful regeneration of retinal axons in adult zebrafish
inferredcites →https://doi.org/10.1002/(sici)1097-4547(19980515)52:4<405::aid-jnr4>3.0.co;2-dopenalex-snapshot
Target contact regulates GAP-43 and ?-tubulin mRNA levels in regenerating retinal ganglion cells
inferredcites →https://doi.org/10.1002/0471142727.mb2129s109openalex-snapshot
ATAC‐seq: A Method for Assaying Chromatin Accessibility Genome‐Wide
inferredcites →https://doi.org/10.1002/cne.23920openalex-snapshot
Matrix metalloproteinases as promising regulators of axonal regrowth in the injured adult zebrafish retinotectal system
inferredcites →https://doi.org/10.1002/dvdy.22190openalex-snapshot
Transcriptional regulatory regions of gap43 needed in developing and regenerating retinal ganglion cells
inferredcites →https://doi.org/10.1002/neu.480240410openalex-snapshot
Expression of JUN, KROX, and CREB transcription factors in goldfish and rat retinal ganglion cells following optic nerve lesion is related to axonal sprouting
inferredcites →https://doi.org/10.1007/s12035-018-1292-5openalex-snapshot
An Antagonistic Axon-Dendrite Interplay Enables Efficient Neuronal Repair in the Adult Zebrafish Central Nervous System
inferredcites →https://doi.org/10.1016/0006-8993(91)91699-2openalex-snapshot
Selective expression of Jun proteins following axotomy and axonal transport block in peripheral nerves in the rat: evidence for a role in the regeneration process
inferredcites →https://doi.org/10.1016/0304-3940(91)90466-7openalex-snapshot
Sequential expression of JUN B, JUN D and FOS B proteins in rat spinal neurons: Cascade of transcriptional operations during nociception
inferredcites →https://doi.org/10.1016/j.cell.2014.08.009openalex-snapshot
Determination and Inference of Eukaryotic Transcription Factor Sequence Specificity
inferredcites →https://doi.org/10.1016/j.cell.2018.01.029openalex-snapshot
The Human Transcription Factors
inferredcites →https://doi.org/10.1016/j.expneurol.2013.03.001openalex-snapshot
Three-dimensional evaluation of retinal ganglion cell axon regeneration and pathfinding in whole mouse tissue after injury
inferredcites →https://doi.org/10.1016/j.expneurol.2017.10.025openalex-snapshot
Zinc chelation and Klf9 knockdown cooperatively promote axon regeneration after optic nerve injury
inferredcites →https://doi.org/10.1016/j.gep.2008.05.002openalex-snapshot
3.6kb Genomic sequence from Takifugu capable of promoting axon growth-associated gene expression in developing and regenerating zebrafish neurons
inferredcites →https://doi.org/10.1016/j.nbd.2012.11.011openalex-snapshot
Long-distance axonal regeneration induced by CNTF gene transfer is impaired by axonal misguidance in the injured adult optic nerve
inferredcites →https://doi.org/10.1016/j.neures.2008.03.008openalex-snapshot
Changes of phospho-growth-associated protein 43 (phospho-GAP43) in the zebrafish retina after optic nerve injury: A long-term observation
inferredcites →https://doi.org/10.1016/j.neuron.2009.11.021openalex-snapshot
SOCS3 Deletion Promotes Optic Nerve Regeneration In Vivo
inferredcites →https://doi.org/10.1016/j.neuron.2015.02.017openalex-snapshot
Subtype-Specific Regeneration of Retinal Ganglion Cells following Axotomy: Effects of Osteopontin and mTOR Signaling
inferredcites →https://doi.org/10.1016/j.neuron.2015.03.060openalex-snapshot
Injury-Induced Decline of Intrinsic Regenerative Ability Revealed by Quantitative Proteomics
inferredcites →https://doi.org/10.1016/j.neuron.2016.01.034openalex-snapshot
A Systems-Level Analysis of the Peripheral Nerve Intrinsic Axonal Growth Program
inferredcites →https://doi.org/10.1016/j.stem.2016.11.006openalex-snapshot
A Multi-step Transcriptional and Chromatin State Cascade Underlies Motor Neuron Programming from Embryonic Stem Cells
inferredcites →https://doi.org/10.1016/j.ydbio.2007.09.019openalex-snapshot
Gene expression analysis of zebrafish retinal ganglion cells during optic nerve regeneration identifies KLF6a and KLF7a as important regulators of axon regeneration
inferredcites →https://doi.org/10.1038/mt.2016.102openalex-snapshot
Boosting Central Nervous System Axon Regeneration by Circumventing Limitations of Natural Cytokine Signaling
inferredcites →https://doi.org/10.1038/nature10594openalex-snapshot
Sustained axon regeneration induced by co-deletion of PTEN and SOCS3
inferredcites →https://doi.org/10.1038/nature11082openalex-snapshot
Topological domains in mammalian genomes identified by analysis of chromatin interactions
inferredcites →https://doi.org/10.1038/nbt.1754openalex-snapshot
Integrative genomics viewer
inferredcites →https://doi.org/10.1038/nbt.3519openalex-snapshot
Near-optimal probabilistic RNA-seq quantification
inferredcites →https://doi.org/10.1038/ncomms5088openalex-snapshot
Tcf3 promotes cell migration and wound repair through regulation of lipocalin 2
inferredcites →https://doi.org/10.1038/nmeth.2688openalex-snapshot
Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position
inferredcites →https://doi.org/10.1038/nmeth.4324openalex-snapshot
Differential analysis of RNA-seq incorporating quantification uncertainty
inferredcites →https://doi.org/10.1038/s41583-018-0001-8openalex-snapshot
Intrinsic mechanisms of neuronal axon regeneration
inferredcites →https://doi.org/10.1038/s41598-017-18757-1openalex-snapshot
Highly conserved molecular pathways, including Wnt signaling, promote functional recovery from spinal cord injury in lampreys
inferredcites →https://doi.org/10.1073/pnas.1621225114openalex-snapshot
Boosting CNS axon regeneration by harnessing antagonistic effects of GSK3 activity
inferredcites →https://doi.org/10.1093/bioinformatics/btp324openalex-snapshot
Fast and accurate short read alignment with Burrows–Wheeler transform
inferredcites →https://doi.org/10.1093/bioinformatics/btp352openalex-snapshot
The Sequence Alignment/Map format and SAMtools
inferredcites →https://doi.org/10.1093/bioinformatics/btr064openalex-snapshot
FIMO: scanning for occurrences of a given motif
inferredcites →https://doi.org/10.1093/bioinformatics/btw313openalex-snapshot
Complex heatmaps reveal patterns and correlations in multidimensional genomic data
inferredcites →https://doi.org/10.1093/biostatistics/kxj037openalex-snapshot
Adjusting batch effects in microarray expression data using empirical Bayes methods
inferredcites →https://doi.org/10.1093/emboj/21.6.1398openalex-snapshot
The Wilms' tumor gene Wt1 is required for normal development of the retina
inferredcites →https://doi.org/10.1093/nar/gkv416openalex-snapshot
The MEME Suite
inferredcites →https://doi.org/10.1093/nar/gkx1126openalex-snapshot
JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework
inferredcites →https://doi.org/10.1101/gr.226233.117openalex-snapshot
Chromatin accessibility dynamics reveal novel functional enhancers in C. elegans
inferredcites →https://doi.org/10.1101/pdb.prot069633openalex-snapshot
Fluorescence-Activated Cell Sorting (FACS) of Fluorescently Tagged Cells from Zebrafish Larvae for RNA Isolation
inferredcites →https://doi.org/10.1111/j.1471-4159.2012.07706.xopenalex-snapshot
Neuronal c‐Jun is required for successful axonal regeneration, but the effects of phosphorylation of its N‐terminus are moderate
inferredcites →https://doi.org/10.1111/j.2517-6161.1995.tb02031.xopenalex-snapshot
Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing
inferredcites →https://doi.org/10.1126/science.1161566openalex-snapshot
Promoting Axon Regeneration in the Adult CNS by Modulation of the PTEN/mTOR Pathway
inferredcites →https://doi.org/10.1146/annurev.ne.12.030189.001015openalex-snapshot
Axonal Growth-Associated Proteins
inferredcites →https://doi.org/10.1177/1759091414562107openalex-snapshot
Connecting the Retina to the Brain
inferredcites →https://doi.org/10.1186/1471-2105-11-165openalex-snapshot
Motif Enrichment Analysis: a unified framework and an evaluation on ChIP data
inferredcites →https://doi.org/10.1186/1471-2105-11-237openalex-snapshot
ChIPpeakAnno: a Bioconductor package to annotate ChIP-seq and ChIP-chip data
inferredcites →https://doi.org/10.1186/gb-2008-9-9-r137openalex-snapshot
Model-based Analysis of ChIP-Seq (MACS)
inferredcites →https://doi.org/10.1186/s13059-014-0550-8openalex-snapshot
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
inferredcites →https://doi.org/10.1242/dev.128.7.1175openalex-snapshot
GAP-43 promoter elements in transgenic zebrafish reveal a difference in signals for axon growth during CNS development and regeneration
inferredcites →https://doi.org/10.1371/journal.pcbi.1003118openalex-snapshot
Software for Computing and Annotating Genomic Ranges
inferredcites →https://doi.org/10.1371/journal.pone.0021800openalex-snapshot
REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms
inferredcites →https://doi.org/10.1523/jneurosci.18-04-01318.1998openalex-snapshot
Peripheral Axotomy Induces Long-Term c-Jun Amino-Terminal Kinase-1 Activation and Activator Protein-1 Binding Activity by c-Jun and junD in Adult Rat Dorsal Root GangliaIn Vivo
inferredcites →https://doi.org/10.1523/jneurosci.2281-04.2004openalex-snapshot
An Element in the α1-Tubulin Promoter Is Necessary for Retinal Expression during Optic Nerve Regeneration But Not after Eye Injury in the Adult Zebrafish
inferredcites →https://doi.org/10.1523/jneurosci.3898-13.2014openalex-snapshot
Jak/Stat Signaling Stimulates Zebrafish Optic Nerve Regeneration and Overcomes the Inhibitory Actions of Socs3 and Sfpq
inferredcites →https://doi.org/10.1534/g3.119.400729openalex-snapshot
Regeneration Rosetta: An Interactive Web Application To Explore Regeneration-Associated Gene Expression and Chromatin Accessibility
inferredcites →https://doi.org/10.3389/fncel.2015.00118openalex-snapshot
Characterization of optic nerve regeneration using transgenic zebrafish
inferredcites →https://doi.org/10.3389/fncel.2015.00251openalex-snapshot
Active mechanistic target of rapamycin plays an ancillary rather than essential role in zebrafish CNS axon regeneration

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1101/2024.05.27.596075openalex-snapshot
Injury distance limits the transcriptional response to spinal injury
inferred← citeshttps://doi.org/10.1534/g3.119.400729openalex-snapshot
Regeneration Rosetta: An Interactive Web Application To Explore Regeneration-Associated Gene Expression and Chromatin Accessibility
inferred← citeshttps://doi.org/10.21037/atm-20-5351openalex-snapshot
The basic science of optic nerve regeneration
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