On the public citation graph

De novo protein design enables precise induction of functional antibodies in vivo

https://doi.org/10.1101/685867
0 signed · 100 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.
Claim with ORCID
Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.
See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/pro.2389openalex-snapshot
Relaxation of backbone bond geometry improves protein energy landscape modeling
inferredcites →https://doi.org/10.1002/pro.2610openalex-snapshot
Rapid search for tertiary fragments reveals protein sequence–structure relationships
inferredcites →https://doi.org/10.1007/s10858-012-9615-8openalex-snapshot
Simultaneous single-structure and bundle representation of protein NMR structures in torsion angle space
inferredcites →https://doi.org/10.1007/s10858-013-9741-yopenalex-snapshot
Protein backbone and sidechain torsion angles predicted from NMR chemical shifts using artificial neural networks
inferredcites →https://doi.org/10.1016/j.antiviral.2013.03.021openalex-snapshot
Broadly neutralizing antibodies against influenza viruses
inferredcites →https://doi.org/10.1016/j.cbpa.2019.06.011openalex-snapshot
Towards functional de novo designed proteins
inferredcites →https://doi.org/10.1016/j.cell.2014.04.034openalex-snapshot
A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells
inferredcites →https://doi.org/10.1016/j.cell.2016.08.005openalex-snapshot
Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies
inferredcites →https://doi.org/10.1016/j.cell.2019.01.046openalex-snapshot
Induction of Potent Neutralizing Antibody Responses by a Designed Protein Nanoparticle Vaccine for Respiratory Syncytial Virus
inferredcites →https://doi.org/10.1016/j.chom.2019.01.010openalex-snapshot
Persistent Antibody Clonotypes Dominate the Serum Response to Influenza over Multiple Years and Repeated Vaccinations
inferredcites →https://doi.org/10.1016/j.coi.2016.05.012openalex-snapshot
Heads, stalks and everything else: how can antibodies eradicate influenza as a human disease?
inferredcites →https://doi.org/10.1016/j.coviro.2015.03.002openalex-snapshot
Neutralizing epitopes on the respiratory syncytial virus fusion glycoprotein
inferredcites →https://doi.org/10.1016/j.jim.2007.09.017openalex-snapshot
Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning
inferredcites →https://doi.org/10.1016/j.jim.2012.09.003openalex-snapshot
Isolation of antibody V(D)J sequences from single cell sorted rhesus macaque B cells
inferredcites →https://doi.org/10.1016/j.jmb.2010.11.008openalex-snapshot
Alternate States of Proteins Revealed by Detailed Energy Landscape Mapping
inferredcites →https://doi.org/10.1016/j.jmb.2011.04.044openalex-snapshot
Design and Characterization of Epitope-Scaffold Immunogens That Present the Motavizumab Epitope from Respiratory Syncytial Virus
inferredcites →https://doi.org/10.1016/j.jsb.2012.09.006openalex-snapshot
RELION: Implementation of a Bayesian approach to cryo-EM structure determination
inferredcites →https://doi.org/10.1016/j.jsb.2015.08.008openalex-snapshot
CTFFIND4: Fast and accurate defocus estimation from electron micrographs
inferredcites →https://doi.org/10.1016/j.jsb.2016.04.010openalex-snapshot
Scipion: A software framework toward integration, reproducibility and validation in 3D electron microscopy
inferredcites →https://doi.org/10.1016/j.molimm.2007.10.016openalex-snapshot
Computational characterization of B-cell epitopes
inferredcites →https://doi.org/10.1016/j.sbi.2015.05.009openalex-snapshot
De novo protein design: how do we expand into the universe of possible protein structures?
inferredcites →https://doi.org/10.1016/j.sbi.2018.06.002openalex-snapshot
Structure-based immunogen design — leading the way to the new age of precision vaccines
inferredcites →https://doi.org/10.1016/j.str.2010.06.010openalex-snapshot
Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope
inferredcites →https://doi.org/10.1016/s0022-2836(02)00241-3openalex-snapshot
Protein NMR Structure Determination with Automated NOE Assignment Using the New Software CANDID and the Torsion Angle Dynamics Algorithm DYANA
inferredcites →https://doi.org/10.1016/s0079-6565(98)00025-9openalex-snapshot
Heteronuclear multidimensional NMR experiments for the structure determination of proteins in solution employing pulsed field gradients
inferredcites →https://doi.org/10.1016/s1359-0278(98)00044-3openalex-snapshot
Proteolytic selection for protein folding using filamentous bacteriophages
inferredcites →https://doi.org/10.1021/bi990765nopenalex-snapshot
Core-Directed Protein Design. I. An Experimental Method for Selecting Stable Proteins from Combinatorial Libraries
inferredcites →https://doi.org/10.1021/cb500241yopenalex-snapshot
Anatomy of β-Strands at Protein–Protein Interfaces
inferredcites →https://doi.org/10.1023/a:1021614115432openalex-snapshot
Protein NMR structure determination with automated NOE-identification in the NOESY spectra using the new software ATNOS
inferredcites →https://doi.org/10.1038/416657aopenalex-snapshot
A ‘periodic table’ for protein structures
inferredcites →https://doi.org/10.1038/nature11371openalex-snapshot
Structural and genetic basis for development of broadly neutralizing influenza antibodies
inferredcites →https://doi.org/10.1038/nature11600openalex-snapshot
Principles for designing ideal protein structures
inferredcites →https://doi.org/10.1038/nature12442openalex-snapshot
Cross-neutralization of four paramyxoviruses by a human monoclonal antibody
inferredcites →https://doi.org/10.1038/nature12966openalex-snapshot
Proof of principle for epitope-focused vaccine design
inferredcites →https://doi.org/10.1038/nature16162openalex-snapshot
Exploring the repeat protein universe through computational protein design
inferredcites →https://doi.org/10.1038/nature18938openalex-snapshot
Structural basis of potent Zika–dengue virus antibody cross-neutralization
inferredcites →https://doi.org/10.1038/nature19946openalex-snapshot
The coming of age of de novo protein design
inferredcites →https://doi.org/10.1038/nature23912openalex-snapshot
Massively parallel de novo protein design for targeted therapeutics
inferredcites →https://doi.org/10.1038/nbt.2214openalex-snapshot
Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing
inferredcites →https://doi.org/10.1038/nbt.3907openalex-snapshot
Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site
inferredcites →https://doi.org/10.1038/nchembio.1966openalex-snapshot
De novo design of a four-fold symmetric TIM-barrel protein with atomic-level accuracy
inferredcites →https://doi.org/10.1038/ncomms12131openalex-snapshot
Envelope-specific B-cell populations in African green monkeys chronically infected with simian immunodeficiency virus
inferredcites →https://doi.org/10.1038/ni.3515openalex-snapshot
Dengue virus sero-cross-reactivity drives antibody-dependent enhancement of infection with zika virus
inferredcites →https://doi.org/10.1038/ni.3680openalex-snapshot
Defining B cell immunodominance to viruses
inferredcites →https://doi.org/10.1038/nmeth.4169openalex-snapshot
cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination
inferredcites →https://doi.org/10.1038/nprot.2006.94openalex-snapshot
Isolating and engineering human antibodies using yeast surface display
inferredcites →https://doi.org/10.1038/nsmb.3267openalex-snapshot
Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV
inferredcites →https://doi.org/10.1038/s41467-017-01858-wopenalex-snapshot
Structural basis of respiratory syncytial virus subtype-dependent neutralization by an antibody targeting the fusion glycoprotein
inferredcites →https://doi.org/10.1038/s41586-018-0830-7openalex-snapshot
De novo design of potent and selective mimics of IL-2 and IL-15
inferredcites →https://doi.org/10.1038/s41590-018-0235-7openalex-snapshot
Recent progress in broadly neutralizing antibodies to HIV
inferredcites →https://doi.org/10.1038/s41591-018-0042-6openalex-snapshot
Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1
inferredcites →https://doi.org/10.1073/pnas.0707977104openalex-snapshot
High-resolution design of a protein loop
inferredcites →https://doi.org/10.1073/pnas.1004728107openalex-snapshot
Elicitation of structure-specific antibodies by epitope scaffolds
inferredcites →https://doi.org/10.1073/pnas.1208984109openalex-snapshot
Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120
inferredcites →https://doi.org/10.1073/pnas.93.1.13openalex-snapshot
Principles of protein-protein interactions.
inferredcites →https://doi.org/10.1084/jem.20151960openalex-snapshot
Reverse vaccinology 2.0: Human immunology instructs vaccine antigen design
inferredcites →https://doi.org/10.1086/514115openalex-snapshot
Development of a Humanized Monoclonal Antibody (MEDI‐493) with Potent In Vitro and In Vivo Activity against Respiratory Syncytial Virus
inferredcites →https://doi.org/10.1101/cshperspect.a030262openalex-snapshot
What Are the Most Powerful Immunogen Design Vaccine Strategies?
inferredcites →https://doi.org/10.1107/s0021889807021206openalex-snapshot
Phaser crystallographic software
inferredcites →https://doi.org/10.1107/s0907444909047337openalex-snapshot
XDS
inferredcites →https://doi.org/10.1107/s0907444909052925openalex-snapshot
PHENIX : a comprehensive Python-based system for macromolecular structure solution
inferredcites →https://doi.org/10.1107/s0907444910007493openalex-snapshot
Features and development of Coot
inferredcites →https://doi.org/10.1111/j.1742-4658.2011.08190.xopenalex-snapshot
Characterizing the complexity of enzymes on the basis of their mechanisms and structures with a bio‐computational analysis
inferredcites →https://doi.org/10.1126/science.1086907openalex-snapshot
Predominant Autoantibody Production by Early Human B Cell Precursors
inferredcites →https://doi.org/10.1126/science.1202617openalex-snapshot
Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin
inferredcites →https://doi.org/10.1126/science.1205669openalex-snapshot
A Neutralizing Antibody Selected from Plasma Cells That Binds to Group 1 and Group 2 Influenza A Hemagglutinins
inferredcites →https://doi.org/10.1126/science.1209368openalex-snapshot
Computation-Guided Backbone Grafting of a Discontinuous Motif onto a Protein Scaffold
inferredcites →https://doi.org/10.1126/science.1218231openalex-snapshot
Linking Crystallographic Model and Data Quality
inferredcites →https://doi.org/10.1126/science.1234914openalex-snapshot
Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody
inferredcites →https://doi.org/10.1126/science.1243283openalex-snapshot
Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus
inferredcites →https://doi.org/10.1126/science.1261172openalex-snapshot
De novo design of a transmembrane Zn 2+ -transporting four-helix bundle
inferredcites →https://doi.org/10.1126/science.aad9195openalex-snapshot
HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen
inferredcites →https://doi.org/10.1126/science.aah7389openalex-snapshot
Principles for designing proteins with cavities formed by curved β sheets
inferredcites →https://doi.org/10.1126/science.aav7541openalex-snapshot
Packing of apolar side chains enables accurate design of highly stable membrane proteins
inferredcites →https://doi.org/10.1126/science.aav9033openalex-snapshot
A proof of concept for structure-based vaccine design targeting RSV in humans
inferredcites →https://doi.org/10.1126/sciimmunol.aaj1879openalex-snapshot
Rapid profiling of RSV antibody repertoires from the memory B cells of naturally infected adult donors
inferredcites →https://doi.org/10.1126/sciimmunol.aax0644openalex-snapshot
B cells engineered to express pathogen-specific antibodies protect against infection
inferredcites →https://doi.org/10.1126/scitranslmed.aac4241openalex-snapshot
Prefusion F–specific antibodies determine the magnitude of RSV neutralizing activity in human sera
inferredcites →https://doi.org/10.1126/scitranslmed.aad0522openalex-snapshot
Immune history profoundly affects broadly protective B cell responses to influenza
inferredcites →https://doi.org/10.1128/jvi.00910-17openalex-snapshot
HIV-1 Cross-Reactive Primary Virus Neutralizing Antibody Response Elicited by Immunization in Nonhuman Primates
inferredcites →https://doi.org/10.1128/jvi.01579-10openalex-snapshot
Structure of a Major Antigenic Site on the Respiratory Syncytial Virus Fusion Glycoprotein in Complex with Neutralizing Antibody 101F
inferredcites →https://doi.org/10.1128/jvi.02871-14openalex-snapshot
High Preexisting Serological Antibody Levels Correlate with Diversification of the Influenza Vaccine Response
inferredcites →https://doi.org/10.1186/s12859-019-2796-3openalex-snapshot
rstoolbox - a Python library for large-scale analysis of computational protein design data and structural bioinformatics
inferredcites →https://doi.org/10.1371/journal.pbio.3000164openalex-snapshot
Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen
inferredcites →https://doi.org/10.1371/journal.pcbi.1006623openalex-snapshot
Rosetta FunFolDes – A general framework for the computational design of functional proteins
inferredcites →https://doi.org/10.1371/journal.ppat.1004103openalex-snapshot
Molecular Signatures of Hemagglutinin Stem-Directed Heterosubtypic Human Neutralizing Antibodies against Influenza A Viruses
inferredcites →https://doi.org/10.1371/journal.ppat.1005859openalex-snapshot
Engineering, Structure and Immunogenicity of the Human Metapneumovirus F Protein in the Postfusion Conformation
inferredcites →https://doi.org/10.1371/journal.ppat.1006837openalex-snapshot
Human antibody recognition of antigenic site IV on Pneumovirus fusion proteins
inferredcites →https://doi.org/10.15252/emmm.201708078openalex-snapshot
Chimeric Pneumoviridae fusion proteins as immunogens to induce cross‐neutralizing antibody responses
inferredcites →https://doi.org/10.2165/00148581-200406030-00004openalex-snapshot
Palivizumab
inferredcites →https://doi.org/10.3389/fimmu.2019.02997openalex-snapshot
Recombinant Influenza Vaccines: Saviors to Overcome Immunodominance
inferredcites →https://doi.org/10.4049/jimmunol.1502543openalex-snapshot
High-Resolution Longitudinal Study of HIV-1 Env Vaccine–Elicited B Cell Responses to the Virus Primary Receptor Binding Site Reveals Affinity Maturation and Clonal Persistence
inferredcites →https://doi.org/10.7554/elife.20352openalex-snapshot
Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1002/1873-3468.13796openalex-snapshot
Synthetic biology principles for the design of protein with novel structures and functions
inferred← citeshttps://doi.org/10.1038/s41467-023-43638-9openalex-snapshot
Engineered immunogens to elicit antibodies against conserved coronavirus epitopes
inferred← citeshttps://doi.org/10.1038/s41589-020-0518-9openalex-snapshot
Computational design of anti-CRISPR proteins with improved inhibition potency
inferred← citeshttps://doi.org/10.1038/s42256-025-01100-zopenalex-snapshot
Efficient protein structure generation with sparse denoising models
inferred← citeshttps://doi.org/10.1101/2020.03.11.988071openalex-snapshot
A bottom-up approach for the de novo design of functional proteins
inferred← citeshttps://doi.org/10.1101/2021.10.11.463937openalex-snapshot
AlphaDesign: A de novo protein design framework based on AlphaFold
inferred← citeshttps://doi.org/10.3389/fimmu.2019.02997openalex-snapshot
Recombinant Influenza Vaccines: Saviors to Overcome Immunodominance
Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.