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Super-resolution microscopy unveils FIP200-scaffolded, cup-shaped organization of mammalian autophagic initiation machinery

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1016/j.bpj.2010.08.012openalex-snapshot
Multicolor Fluorescence Nanoscopy in Fixed and Living Cells by Exciting Conventional Fluorophores with a Single Wavelength
inferredcites →https://doi.org/10.1016/j.ceb.2009.11.014openalex-snapshot
Mammalian autophagy: core molecular machinery and signaling regulation
inferredcites →https://doi.org/10.1016/j.ceb.2014.02.005openalex-snapshot
The protein-vesicle network of autophagy
inferredcites →https://doi.org/10.1016/j.ceb.2016.02.010openalex-snapshot
Structure and function of the ULK1 complex in autophagy
inferredcites →https://doi.org/10.1016/j.cell.2011.10.026openalex-snapshot
Autophagy: Renovation of Cells and Tissues
inferredcites →https://doi.org/10.1016/j.molcel.2014.05.021openalex-snapshot
WIPI2 Links LC3 Conjugation with PI3P, Autophagosome Formation, and Pathogen Clearance by Recruiting Atg12–5-16L1
inferredcites →https://doi.org/10.1016/j.molcel.2015.02.033openalex-snapshot
Imaging Live-Cell Dynamics and Structure at the Single-Molecule Level
inferredcites →https://doi.org/10.1021/nl801471dopenalex-snapshot
Multicolor Far-Field Fluorescence Nanoscopy through Isolated Detection of Distinct Molecular Species
inferredcites →https://doi.org/10.1038/embor.2013.6openalex-snapshot
FIP200 regulates targeting of Atg16L1 to the isolation membrane
inferredcites →https://doi.org/10.1038/ncomms12420openalex-snapshot
Autophagy initiation by ULK complex assembly on ER tubulovesicular regions marked by ATG9 vesicles
inferredcites →https://doi.org/10.1038/ncomms8384openalex-snapshot
Graphene-enabled electron microscopy and correlated super-resolution microscopy of wet cells
inferredcites →https://doi.org/10.1038/nmeth929openalex-snapshot
Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM)
inferredcites →https://doi.org/10.1038/nrm.2017.71openalex-snapshot
Fluorescence nanoscopy in cell biology
inferredcites →https://doi.org/10.1038/s41580-018-0003-4openalex-snapshot
Mechanism and medical implications of mammalian autophagy
inferredcites →https://doi.org/10.1073/pnas.1421092112openalex-snapshot
Atg13 HORMA domain recruits Atg9 vesicles during autophagosome formation
inferredcites →https://doi.org/10.1073/pnas.1814810115openalex-snapshot
TANGO1 and SEC12 are copackaged with procollagen I to facilitate the generation of large COPII carriers
inferredcites →https://doi.org/10.1074/jbc.m900573200openalex-snapshot
ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy
inferredcites →https://doi.org/10.1074/jbc.r117.810366openalex-snapshot
A molecular perspective of mammalian autophagosome biogenesis
inferredcites →https://doi.org/10.1083/jcb.152.4.657openalex-snapshot
Dissection of Autophagosome Formation Using Apg5-Deficient Mouse Embryonic Stem Cells
inferredcites →https://doi.org/10.1083/jcb.200712064openalex-snapshot
FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells
inferredcites →https://doi.org/10.1083/jcb.201312062openalex-snapshot
Concentration of Sec12 at ER exit sites via interaction with cTAGE5 is required for collagen export
inferredcites →https://doi.org/10.1091/mbc.e04-08-0669openalex-snapshot
Atg17 Functions in Cooperation with Atg1 and Atg13 in Yeast Autophagy
inferredcites →https://doi.org/10.1091/mbc.e08-12-1248openalex-snapshot
Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy
inferredcites →https://doi.org/10.1091/mbc.e08-12-1249openalex-snapshot
ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery
inferredcites →https://doi.org/10.1091/mbc.e13-07-0381openalex-snapshot
ER exit sites are physical and functional core autophagosome biogenesis components
inferredcites →https://doi.org/10.1126/science.1153529openalex-snapshot
Three-Dimensional Super-Resolution Imaging by Stochastic Optical Reconstruction Microscopy
inferredcites →https://doi.org/10.1126/science.aau1044openalex-snapshot
Visualizing and discovering cellular structures with super-resolution microscopy
inferredcites →https://doi.org/10.1146/annurev-biochem-061516-044820openalex-snapshot
Mechanisms of Autophagy Initiation
inferredcites →https://doi.org/10.1146/annurev-biophys-060414-034248openalex-snapshot
Mechanisms of Autophagy
inferredcites →https://doi.org/10.1146/annurev-cellbio-092910-154005openalex-snapshot
The Role of Atg Proteins in Autophagosome Formation
inferredcites →https://doi.org/10.1152/physrev.00030.2009openalex-snapshot
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
inferredcites →https://doi.org/10.1242/jcs.00381openalex-snapshot
Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate
inferredcites →https://doi.org/10.1371/journal.pcbi.1005817openalex-snapshot
Scaffolding the cup-shaped double membrane in autophagy
inferredcites →https://doi.org/10.15252/embj.201695189openalex-snapshot
Autophagosome formation is initiated at phosphatidylinositol synthase‐enriched ER subdomains
inferredcites →https://doi.org/10.15252/embr.201744559openalex-snapshot
Remodeling of ER‐exit sites initiates a membrane supply pathway for autophagosome biogenesis
inferredcites →https://doi.org/10.4161/auto.25529openalex-snapshot
Temporal analysis of recruitment of mammalian ATG proteins to the autophagosome formation site
inferredcites →https://doi.org/10.7554/elife.04135openalex-snapshot
Phosphatidylinositol 3-kinase and COPII generate LC3 lipidation vesicles from the ER-Golgi intermediate compartment
inferredcites →https://doi.org/10.7554/elife.11205openalex-snapshot
Translocation of interleukin-1β into a vesicle intermediate in autophagy-mediated secretion

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1007/978-1-0716-2671-9_21openalex-snapshot
Unveiling the Nanoscale Dynamics of the Exocytic Machinery in Chromaffin Cells with Single-Molecule Imaging
inferred← citeshttps://doi.org/10.1016/j.mbplus.2021.100089openalex-snapshot
Cooperation of cell adhesion and autophagy in the brain: Functional roles in development and neurodegenerative disease
inferred← citeshttps://doi.org/10.1083/jcb.201911047openalex-snapshot
ULK complex organization in autophagy by a C-shaped FIP200 N-terminal domain dimer
inferred← citeshttps://doi.org/10.1101/2020.07.07.191189openalex-snapshot
FIP200 organizes the autophagy machinery at p62-ubiquitin condensates beyond activation of the ULK1 kinase
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