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Non-apoptotic caspase activation sustains ovarian somatic stem cell functions by modulating Hedgehog-signalling and autophagy

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/bies.201300052openalex-snapshot
Cell death proteins: An evolutionary role in cellular adaptation before the advent of apoptosis
inferredcites →https://doi.org/10.1007/978-1-4939-2851-4_4openalex-snapshot
Genetic Mosaic Analysis of Stem Cell Lineages in the Drosophila Ovary
inferredcites →https://doi.org/10.1007/978-1-4939-6371-3_3openalex-snapshot
The Q-System: A Versatile Expression System for Drosophila
inferredcites →https://doi.org/10.1016/0925-4773(95)00397-jopenalex-snapshot
The Drosophila cubitus interruptus protein and its role in the wingless and hedgehog signal transduction pathways
inferredcites →https://doi.org/10.1016/j.canep.2015.11.014openalex-snapshot
Hedgehog signaling pathway as a therapeutic target for ovarian cancer
inferredcites →https://doi.org/10.1016/j.celrep.2014.03.020openalex-snapshot
Fly-FUCCI: A Versatile Tool for Studying Cell Proliferation in Complex Tissues
inferredcites →https://doi.org/10.1016/j.devcel.2004.09.018openalex-snapshot
Drosophila Caspase DRONC Is Required for Specific Developmental Cell Death Pathways and Stress-Induced Apoptosis
inferredcites →https://doi.org/10.1016/j.devcel.2011.06.018openalex-snapshot
Drosophila Stem Cell Niches: A Decade of Discovery Suggests a Unified View of Stem Cell Regulation
inferredcites →https://doi.org/10.1016/j.devcel.2015.11.003openalex-snapshot
Translational Control of Autophagy by Orb in the Drosophila Germline
inferredcites →https://doi.org/10.1016/j.devcel.2018.08.008openalex-snapshot
Opposing Action of Hedgehog and Insulin Signaling Balances Proliferation and Autophagy to Determine Follicle Stem Cell Lifespan
inferredcites →https://doi.org/10.1016/j.devcel.2020.03.015openalex-snapshot
Non-Canonical Caspase Activity Antagonizes p38 MAPK Stress-Priming Function to Support Development
inferredcites →https://doi.org/10.1016/j.semcdb.2014.03.031openalex-snapshot
Genetics and mechanisms of ovarian cancer: Parallels between Drosophila and humans
inferredcites →https://doi.org/10.1016/j.semcdb.2017.11.009openalex-snapshot
Caspase signaling, a conserved inductive cue for metazoan cell differentiation
inferredcites →https://doi.org/10.1016/j.semcdb.2018.01.005openalex-snapshot
All about the caspase-dependent functions without cell death
inferredcites →https://doi.org/10.1016/s0076-6879(08)03612-4openalex-snapshot
Chapter 12 Monitoring Autophagic Degradation of p62/SQSTM1
inferredcites →https://doi.org/10.1016/s1097-2765(00)00045-9openalex-snapshot
In Vivo Functions of the Patched Protein
inferredcites →https://doi.org/10.1038/35069099openalex-snapshot
Hedgehog acts as a somatic stem cell factor in the Drosophila ovary
inferredcites →https://doi.org/10.1038/416755aopenalex-snapshot
Cells compete for Decapentaplegic survival factor to prevent apoptosis in Drosophila wing development
inferredcites →https://doi.org/10.1038/cdd.2017.111openalex-snapshot
CDPs: caspase-dependent non-lethal cellular processes
inferredcites →https://doi.org/10.1038/cdd.2017.37openalex-snapshot
Evolution of caspase-mediated cell death and differentiation: twins separated at birth
inferredcites →https://doi.org/10.1038/cdd.2017.64openalex-snapshot
More alive than dead: non-apoptotic roles for caspases in neuronal development, plasticity and disease
inferredcites →https://doi.org/10.1038/hdy.1995.30openalex-snapshot
Within- and between-generation effects of temperature on early fecundity of Drosophila melanogaster
inferredcites →https://doi.org/10.1038/ncb1880openalex-snapshot
The Patched dependence receptor triggers apoptosis through a DRAL–caspase-9 complex
inferredcites →https://doi.org/10.1038/ncomms2212openalex-snapshot
The Hedgehog signalling pathway regulates autophagy
inferredcites →https://doi.org/10.1038/nmeth.2089openalex-snapshot
NIH Image to ImageJ: 25 years of image analysis
inferredcites →https://doi.org/10.1038/nrm3598openalex-snapshot
The mechanisms of Hedgehog signalling and its roles in development and disease
inferredcites →https://doi.org/10.1038/nsb989openalex-snapshot
Molecular mechanism of Reaper-Grim-Hid-mediated suppression of DIAP1-dependent Dronc ubiquitination
inferredcites →https://doi.org/10.1038/s41419-020-2502-4openalex-snapshot
Apoptosome-dependent myotube formation involves activation of caspase-3 in differentiating myoblasts
inferredcites →https://doi.org/10.1038/s41467-017-01322-9openalex-snapshot
Quantitative microscopy of the Drosophila ovary shows multiple niche signals specify progenitor cell fate
inferredcites →https://doi.org/10.1038/sj.cdd.4401868openalex-snapshot
Systematic in vivo RNAi analysis of putative components of the Drosophila cell death machinery
inferredcites →https://doi.org/10.1038/sj.cdd.4401920openalex-snapshot
The effector caspases drICE and dcp-1 have partially overlapping functions in the apoptotic pathway in Drosophila
inferredcites →https://doi.org/10.1038/sj.cr.7310123openalex-snapshot
The Drosophila ovary: an active stem cell community
inferredcites →https://doi.org/10.1038/srep09015openalex-snapshot
In vivo CaspaseTracker biosensor system for detecting anastasis and non-apoptotic caspase activity
inferredcites →https://doi.org/10.1073/pnas.1006610107openalex-snapshot
Metacaspase Yca1 is required for clearance of insoluble protein aggregates
inferredcites →https://doi.org/10.1073/pnas.1200094109openalex-snapshot
Patched dependence receptor triggers apoptosis through ubiquitination of caspase-9
inferredcites →https://doi.org/10.1073/pnas.1300725110openalex-snapshot
Castor is required for Hedgehog-dependent cell-fate specification and follicle stem cell maintenance in Drosophila oogenesis
inferredcites →https://doi.org/10.1073/pnas.1904647116openalex-snapshot
Dronc-independent basal executioner caspase activity sustains Drosophila imaginal tissue growth
inferredcites →https://doi.org/10.1074/jbc.c300028200openalex-snapshot
dSmurf Selectively Degrades Decapentaplegic-activated MAD, and Its Overexpression Disrupts Imaginal Disc Development
inferredcites →https://doi.org/10.1080/15548627.2015.1066957openalex-snapshot
Bafilomycin A1 disrupts autophagic flux by inhibiting both V-ATPase-dependent acidification and Ca-P60A/SERCA-dependent autophagosome-lysosome fusion
inferredcites →https://doi.org/10.1083/jcb.200711108openalex-snapshot
Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain
inferredcites →https://doi.org/10.1083/jcb.201212094openalex-snapshot
Diet controls Drosophila follicle stem cell proliferation via Hedgehog sequestration and release
inferredcites →https://doi.org/10.1083/jcb.201309141openalex-snapshot
Coupling of Hedgehog and Hippo pathways promotes stem cell maintenance by stimulating proliferation
inferredcites →https://doi.org/10.1083/jcb.201706134openalex-snapshot
A molecular signature for anastasis, recovery from the brink of apoptotic cell death
inferredcites →https://doi.org/10.1093/carcin/bgn230openalex-snapshot
Aberrant activation of hedgehog signaling pathway in ovarian cancers: effect on prognosis, cell invasion and differentiation
inferredcites →https://doi.org/10.1095/biolreprod.112.100859openalex-snapshot
Hedgehog Signaling in Follicle Development1
inferredcites →https://doi.org/10.1101/707380openalex-snapshot
Non-apoptotic caspase-dependent regulation of enteroblast quiescence in Drosophila
inferredcites →https://doi.org/10.1101/gad.1461306openalex-snapshot
The C-terminal tail of the Hedgehog receptor Patched regulates both localization and turnover
inferredcites →https://doi.org/10.1111/j.1365-2796.2005.01570.xopenalex-snapshot
Apoptosis: a basic biological phenomenon with wide‐ranging implications in human disease
inferredcites →https://doi.org/10.1126/scisignal.aan8660openalex-snapshot
Hedgehog reciprocally controls trafficking of Smo and Ptc through the Smurf family of E3 ubiquitin ligases
inferredcites →https://doi.org/10.1146/annurev.neuro.051508.135600openalex-snapshot
The Glial Nature of Embryonic and Adult Neural Stem Cells
inferredcites →https://doi.org/10.1155/2014/498491openalex-snapshot
Autophagy in Alcohol-Induced Multiorgan Injury: Mechanisms and Potential Therapeutic Targets
inferredcites →https://doi.org/10.1242/dev.00933openalex-snapshot
Caspases function in autophagic programmed cell death inDrosophila
inferredcites →https://doi.org/10.1242/dev.035329openalex-snapshot
Hedgehog-stimulated stem cells depend on non-canonical activity of the Notch co-activator Mastermind
inferredcites →https://doi.org/10.1242/dev.058347openalex-snapshot
Dronc caspase exerts a non-apoptotic function to restrain phospho-Numb-induced ectopic neuroblast formation in Drosophila
inferredcites →https://doi.org/10.1242/dev.098558openalex-snapshot
A dynamic population of stromal cells contributes to the follicle stem cell niche in the Drosophila ovary
inferredcites →https://doi.org/10.1242/dev.100933openalex-snapshot
Accelerated homologous recombination and subsequent genome modification in Drosophila
inferredcites →https://doi.org/10.1242/dev.118.2.401openalex-snapshot
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
inferredcites →https://doi.org/10.1242/dev.120.8.2121openalex-snapshot
Expression of baculovirus P35 prevents cell death in Drosophila
inferredcites →https://doi.org/10.1242/dev.129.8.1839openalex-snapshot
A positive role for Patched-Smoothened signaling in promoting cell proliferation during normal head development inDrosophila
inferredcites →https://doi.org/10.1242/dev.147702openalex-snapshot
Yorkie and Hedgehog independently restrict BMP production in escort cells to permit germline differentiation in the Drosophila ovary
inferredcites →https://doi.org/10.1242/dev.170811openalex-snapshot
Novel initiator caspase reporters uncover previously unknown features of caspase-activating cells
inferredcites →https://doi.org/10.1242/jcs.00158openalex-snapshot
Hedgehogs tryst with the cell cycle
inferredcites →https://doi.org/10.1242/jcs.01376openalex-snapshot
Mechanism of Dronc activation in Drosophila cells
inferredcites →https://doi.org/10.1371/journal.pbio.1001298openalex-snapshot
Cytoneme-Mediated Delivery of Hedgehog Regulates the Expression of Bone Morphogenetic Proteins to Maintain Germline Stem Cells in Drosophila
inferredcites →https://doi.org/10.1371/journal.pgen.1002261openalex-snapshot
Drosophila IAP1-Mediated Ubiquitylation Controls Activation of the Initiator Caspase DRONC Independent of Protein Degradation
inferredcites →https://doi.org/10.1371/journal.pgen.1007024openalex-snapshot
p53-dependent programmed necrosis controls germ cell homeostasis during spermatogenesis
inferredcites →https://doi.org/10.1371/journal.pone.0029024openalex-snapshot
Revisiting G3BP1 as a RasGAP Binding Protein: Sensitization of Tumor Cells to Chemotherapy by the RasGAP 317–326 Sequence Does Not Involve G3BP1
inferredcites →https://doi.org/10.1534/genetics.103.024323openalex-snapshot
Translating Available Food Into the Number of Eggs Laid by Drosophila melanogaster
inferredcites →https://doi.org/10.1534/genetics.106.065961openalex-snapshot
The Carnegie Protein Trap Library: A Versatile Tool for Drosophila Developmental Studies
inferredcites →https://doi.org/10.1534/genetics.114.173617openalex-snapshot
Novel Tools for Genetic Manipulation of Follicle Stem Cells in the Drosophila Ovary Reveal an Integrin-Dependent Transition from Quiescence to Proliferation
inferredcites →https://doi.org/10.1677/joe.1.06220openalex-snapshot
Nutritional status affects 20-hydroxyecdysone concentration and progression of oogenesis in Drosophila melanogaster
inferredcites →https://doi.org/10.3390/ijms14011179openalex-snapshot
Hedgehog Signaling Pathway in Ovarian Cancer
inferredcites →https://doi.org/10.3892/ijo.2011.1093openalex-snapshot
Hedgehog signaling pathway regulates the growth of ovarian cancer spheroid forming cells
inferredcites →https://doi.org/10.4161/cc.6.2.3745openalex-snapshot
A General Role of Hedgehog in the Regulation of Proliferation
inferredcites →https://doi.org/10.7150/ijbs.30369openalex-snapshot
Autophagy in Ovarian Follicular Development and Atresia
inferredcites →https://doi.org/10.7150/jca.17712openalex-snapshot
Hedgehog signaling pathway regulates ovarian cancer invasion and migration via adhesion molecule CD24
inferredcites →https://doi.org/10.7554/elife.10936openalex-snapshot
CasExpress reveals widespread and diverse patterns of cell survival of caspase-3 activation during development in vivo

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1016/j.celrep.2022.110718openalex-snapshot
Non-apoptotic activation of Drosophila caspase-2/9 modulates JNK signaling, the tumor microenvironment, and growth of wound-like tumors
inferred← citeshttps://doi.org/10.1111/febs.16418openalex-snapshot
Caspases help to spread the message via extracellular vesicles
inferred← citeshttps://doi.org/10.3390/ijms22168927openalex-snapshot
The Duality of Caspases in Cancer, as Told through the Fly
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