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A loss-of-function mutation in Itgal contributes to the high susceptibility of Collaborative Cross strain CC042 to Salmonella infections
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/art.10234openalex-snapshot
Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus
inferredcites →https://doi.org/10.1007/s00335-007-9045-1openalex-snapshot
The polymorphism architecture of mouse genetic resources elucidated using genome-wide resequencing data: implications for QTL discovery and systems genetics
inferredcites →https://doi.org/10.1007/s00335-008-9134-9openalex-snapshot
Establishment of “The Gene Mine”: a resource for rapid identification of complex trait genes
inferredcites →https://doi.org/10.1007/s00335-015-9581-zopenalex-snapshot
Informatics resources for the Collaborative Cross and related mouse populations
inferredcites →https://doi.org/10.1007/s00335-018-9749-4openalex-snapshot
Enterobacteria and host resistance to infection
inferredcites →https://doi.org/10.1016/j.cell.2008.10.048openalex-snapshot
Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair
inferredcites →https://doi.org/10.1016/j.chom.2019.03.009openalex-snapshot
The Collaborative Cross: A Systems Genetics Resource for Studying Host-Pathogen Interactions
inferredcites →https://doi.org/10.1016/j.cyto.2016.10.009openalex-snapshot
Interferon-γ in Salmonella pathogenesis: New tricks for an old dog
inferredcites →https://doi.org/10.1016/j.molcel.2017.10.003openalex-snapshot
Extracellular ISG15 Signals Cytokine Secretion through the LFA-1 Integrin Receptor
inferredcites →https://doi.org/10.1016/j.stem.2014.07.005openalex-snapshot
Identification of Regulatory Networks in HSCs and Their Immediate Progeny via Integrated Proteome, Transcriptome, and DNA Methylome Analysis
inferredcites →https://doi.org/10.1016/j.tig.2019.04.003openalex-snapshot
High-Diversity Mouse Populations for Complex Traits
inferredcites →https://doi.org/10.1016/s0140-6736(12)61728-0openalex-snapshot
Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010
inferredcites →https://doi.org/10.1038/emboj.2013.33openalex-snapshot
A role for LFA‐1 in delaying T‐lymphocyte egress from lymph nodes
inferredcites →https://doi.org/10.1038/gene.2013.70openalex-snapshot
A gene pathway analysis highlights the role of cellular adhesion molecules in multiple sclerosis susceptibility
inferredcites →https://doi.org/10.1038/ng.3760openalex-snapshot
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
inferredcites →https://doi.org/10.1038/ng1104-1133openalex-snapshot
The Collaborative Cross, a community resource for the genetic analysis of complex traits
inferredcites →https://doi.org/10.1038/nri2986openalex-snapshot
The insider's guide to leukocyte integrin signalling and function
inferredcites →https://doi.org/10.1038/nri3858openalex-snapshot
Genetic susceptibility to invasive Salmonella disease
inferredcites →https://doi.org/10.1038/nrmicro3420openalex-snapshot
Salmonellae interactions with host processes
inferredcites →https://doi.org/10.1046/j.1365-2567.1997.00183.xopenalex-snapshot
Treatment with anti‐LFA‐1α monoclonal antibody selectively interferes with the maturation of CD4−8+ thymocytes
inferredcites →https://doi.org/10.1083/jcb.201609072openalex-snapshot
A novel intracellular pool of LFA-1 is critical for asymmetric CD8+ T cell activation and differentiation
inferredcites →https://doi.org/10.1084/jem.189.4.615openalex-snapshot
Endotoxin-tolerant Mice Have Mutations in Toll-like Receptor 4 ( Tlr4 )
inferredcites →https://doi.org/10.1086/650733openalex-snapshot
The Global Burden of Nontyphoidal Salmonella Gastroenteritis
inferredcites →https://doi.org/10.1089/jir.2013.0050openalex-snapshot
Innate Defects of the IL-12/IFN-γ Axis in Susceptibility to Infections by Mycobacteria and Salmonella
inferredcites →https://doi.org/10.1093/bioinformatics/btg112openalex-snapshot
R/qtl: QTL mapping in experimental crosses
inferredcites →https://doi.org/10.1093/ilar.52.1.24openalex-snapshot
The Collaborative Cross: A Recombinant Inbred Mouse Population for the Systems Genetic Era
inferredcites →https://doi.org/10.1093/jtm/taw086openalex-snapshot
Gut microbiota-mediated protection against diarrheal infections
inferredcites →https://doi.org/10.1101/gr.111310.110openalex-snapshot
Genetic analysis of complex traits in the emerging Collaborative Cross
inferredcites →https://doi.org/10.1111/j.1600-065x.2010.00999.xopenalex-snapshot
Immunity to salmonellosis
inferredcites →https://doi.org/10.1111/j.1749-6632.2011.06389.xopenalex-snapshot
Leukocyte adhesion deficiencies
inferredcites →https://doi.org/10.1128/iai.00749-12openalex-snapshot
CD11a Regulates Effector CD8 T Cell Differentiation and Central Memory Development in Response to Infection with Listeria monocytogenes
inferredcites →https://doi.org/10.1128/iai.62.7.2702-2706.1994openalex-snapshot
Listeria monocytogenes, but not Salmonella typhimurium, elicits a CD18-independent mechanism of neutrophil extravasation into the murine peritoneal cavity
inferredcites →https://doi.org/10.1128/iai.66.10.4767-4776.1998openalex-snapshot
Interleukin-12 Is Required for Control of the Growth of Attenuated Aromatic-Compound-Dependent Salmonellae in BALB/c Mice: Role of Gamma Interferon and Macrophage Activation
inferredcites →https://doi.org/10.1128/jvi.78.6.3014-3023.2004openalex-snapshot
Treatment with Anti-LFA-1 Delays the CD8+Cytotoxic-T-Lymphocyte Response and Viral Clearance in Mice with Primary Respiratory Syncytial Virus Infection
inferredcites →https://doi.org/10.1128/mbio.01516-16openalex-snapshot
Tuberculosis Susceptibility and Vaccine Protection Are Independently Controlled by Host Genotype
inferredcites →https://doi.org/10.1186/1476-0711-8-15openalex-snapshot
Non-typhoidal Salmonella bacteraemia: Epidemiology, clinical characteristics and its' association with severe immunosuppression
inferredcites →https://doi.org/10.1186/s12864-018-4667-0openalex-snapshot
Identification of new loci involved in the host susceptibility to Salmonella Typhimurium in collaborative cross mice
inferredcites →https://doi.org/10.1371/journal.ppat.1004914openalex-snapshot
Activation of Salmonella Typhi-Specific Regulatory T Cells in Typhoid Disease in a Wild-Type S. Typhi Challenge Model
inferredcites →https://doi.org/10.1534/g3.111.001768openalex-snapshot
HTreeQA: Using Semi-Perfect Phylogeny Trees in Quantitative Trait Loci Study on Genotype Data
inferredcites →https://doi.org/10.1534/g3.115.022087openalex-snapshot
The Mouse Universal Genotyping Array: From Substrains to Subspecies
inferredcites →https://doi.org/10.1534/genetics.116.198838openalex-snapshot
Genomes of the Mouse Collaborative Cross
inferredcites →https://doi.org/10.1681/asn.v11suppl_2s101openalex-snapshot
Effect of the Genetic Background on the Phenotype of Mouse Mutations
inferredcites →https://doi.org/10.3389/fimmu.2017.01291openalex-snapshot
LFA-1 Mediates Cytotoxicity and Tissue Migration of Specific CD8+ T Cells after Heterologous Prime-Boost Vaccination against Trypanosoma cruzi Infection
inferredcites →https://doi.org/10.3389/fimmu.2017.01866openalex-snapshot
β2 Integrins As Regulators of Dendritic Cell, Monocyte, and Macrophage Function
inferredcites →https://doi.org/10.4049/jimmunol.1301370openalex-snapshot
Altered IFN-γ–Mediated Immunity and Transcriptional Expression Patterns in N-Ethyl-N-Nitrosourea–Induced STAT4 Mutants Confer Susceptibility to Acute Typhoid-like Disease
inferredcites →https://doi.org/10.4049/jimmunol.1301820openalex-snapshot
CD11a Is Essential for Normal Development of Hematopoietic Intermediates
inferredcites →https://doi.org/10.4049/jimmunol.147.9.2852openalex-snapshot
The role of LFA-1/ICAM-1 interactions during murine T lymphocyte development
inferredcites →https://doi.org/10.4049/jimmunol.166.12.7362openalex-snapshot
The Differential Roles of LFA-1 and Mac-1 in Host Defense Against Systemic Infection with Streptococcus pneumoniae
inferredcites →https://doi.org/10.4049/jimmunol.170.10.5228openalex-snapshot
Neutrophilia in LFA-1-Deficient Mice Confers Resistance to Listeriosis: Possible Contribution of Granulocyte-Colony-Stimulating Factor and IL-17
inferredcites →https://doi.org/10.4049/jimmunol.176.8.4914openalex-snapshot
The LFA-1 Adhesion Molecule Is Required for Protective Immunity during Pulmonary Mycobacterium tuberculosis Infection
inferredcites →https://doi.org/10.4269/ajtmh.18-0032openalex-snapshot
Introductory Article on Global Burden and Epidemiology of Typhoid Fever
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1128/mbio.02791-19openalex-snapshot
Functionally Overlapping Variants Control Tuberculosis Susceptibility in Collaborative Cross Mice
inferred← citeshttps://doi.org/10.1186/s12711-021-00694-3openalex-snapshot
Non-additive QTL mapping of lactation traits in 124,000 cattle reveals novel recessive loci
inferred← citeshttps://doi.org/10.7554/elife.65846openalex-snapshot
Linking functional and molecular mechanisms of host resilience to malaria infection
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