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Inhibition of Microbial Beta-Glucuronidase Does Not Prevent Breast Carcinogenesis in the Polyoma Middle T Mouse

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/s10549-014-3086-4openalex-snapshot
Vaccination with ErbB-2 peptides prevents cancer stem cell expansion and suppresses the development of spontaneous tumors in MMTV-PyMT transgenic mice
inferredcites →https://doi.org/10.1007/s10911-019-09433-3openalex-snapshot
How to Choose a Mouse Model of Breast Cancer, a Genomic Perspective
inferredcites →https://doi.org/10.1007/s12672-017-0285-6openalex-snapshot
MMTV-PyMT and Derived Met-1 Mouse Mammary Tumor Cells as Models for Studying the Role of the Androgen Receptor in Triple-Negative Breast Cancer Progression
inferredcites →https://doi.org/10.1007/s13277-012-0458-4openalex-snapshot
Characterization of mammary cancer stem cells in the MMTV-PyMT mouse model
inferredcites →https://doi.org/10.1016/bs.pmbts.2017.07.004openalex-snapshot
Microbiota and Breast Cancer
inferredcites →https://doi.org/10.1016/j.cbpa.2013.04.011openalex-snapshot
The human microbiome is a source of therapeutic drug targets
inferredcites →https://doi.org/10.1016/j.chembiol.2015.08.005openalex-snapshot
Structure and Inhibition of Microbiome β-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity
inferredcites →https://doi.org/10.1016/j.immuni.2014.06.014openalex-snapshot
Symbiotic Bacterial Metabolites Regulate Gastrointestinal Barrier Function via the Xenobiotic Sensor PXR and Toll-like Receptor 4
inferredcites →https://doi.org/10.1016/j.maturitas.2017.06.025openalex-snapshot
Estrogen–gut microbiome axis: Physiological and clinical implications
inferredcites →https://doi.org/10.1016/s0002-9440(10)63568-7openalex-snapshot
Progression to Malignancy in the Polyoma Middle T Oncoprotein Mouse Breast Cancer Model Provides a Reliable Model for Human Diseases
inferredcites →https://doi.org/10.1021/acscentsci.8b00239openalex-snapshot
Gut Microbial β-Glucuronidase Inhibition via Catalytic Cycle Interception
inferredcites →https://doi.org/10.1038/nrc.2016.116openalex-snapshot
Deciphering the divergent roles of progestogens in breast cancer
inferredcites →https://doi.org/10.1038/s41598-018-26506-1openalex-snapshot
Long-Term Administration of Conjugated Estrogen and Bazedoxifene Decreased Murine Fecal β-Glucuronidase Activity Without Impacting Overall Microbiome Community
inferredcites →https://doi.org/10.1038/s41598-018-36069-wopenalex-snapshot
Structure, function, and inhibition of drug reactivating human gut microbial β-glucuronidases
inferredcites →https://doi.org/10.1038/sj.onc.1203270openalex-snapshot
A mammary-specific model demonstrates the role of the p53 tumor suppressor gene in tumor development
inferredcites →https://doi.org/10.1038/srep28061openalex-snapshot
Characterization of the microbiome of nipple aspirate fluid of breast cancer survivors
inferredcites →https://doi.org/10.1056/nejm198212163072502openalex-snapshot
Estrogen Excretion Patterns and Plasma Levels in Vegetarian and Omnivorous Women
inferredcites →https://doi.org/10.1074/jbc.r116.767434openalex-snapshot
Glucuronides in the gut: Sugar-driven symbioses between microbe and host
inferredcites →https://doi.org/10.1074/jbc.ra118.005414openalex-snapshot
Three structurally and functionally distinct β-glucuronidases from the human gut microbe Bacteroides uniformis
inferredcites →https://doi.org/10.1089/sur.2017.245openalex-snapshot
Microbial Glucuronidase Inhibition Reduces Severity of Diclofenac-Induced Anastomotic Leak in Rats
inferredcites →https://doi.org/10.1093/carcin/bgl190openalex-snapshot
Mice expressing myrAKT1 in the mammary gland develop carcinogen-induced ER-positive mammary tumors that mimic human breast cancer
inferredcites →https://doi.org/10.1093/carcin/bgm170openalex-snapshot
-Glucuronidase in human intestinal microbiota is necessary for the colonic genotoxicity of the food-borne carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline in rats
inferredcites →https://doi.org/10.1093/jnci/88.13.899openalex-snapshot
Wheat Bran and Psylium Diets: Effects on N-Methylnitrosourea-Induced Mammary Tumorigenesis in F344 Rats
inferredcites →https://doi.org/10.1093/jnci/djr393openalex-snapshot
Assessment of Ki67 in Breast Cancer: Recommendations from the International Ki67 in Breast Cancer Working Group
inferredcites →https://doi.org/10.1093/jnci/djw029openalex-snapshot
The Intestinal Microbiome and Estrogen Receptor–Positive Female Breast Cancer
inferredcites →https://doi.org/10.1093/toxsci/kfs310openalex-snapshot
Multiple NSAID-Induced Hits Injure the Small Intestine: Underlying Mechanisms and Novel Strategies
inferredcites →https://doi.org/10.1097/00000658-199307000-00004openalex-snapshot
Immunohistochemical and Biochemical Measurement of Estrogen and Progesterone Receptors in Primary Breast Cancer Correlation of Histopathology and Prognostic Factors
inferredcites →https://doi.org/10.1124/jpet.111.191122openalex-snapshot
Pharmacologic Targeting of Bacterial β-Glucuronidase Alleviates Nonsteroidal Anti-Inflammatory Drug-Induced Enteropathy in Mice
inferredcites →https://doi.org/10.1124/mol.113.085852openalex-snapshot
Molecular Insights into Microbial β-Glucuronidase Inhibition to Abrogate CPT-11 Toxicity
inferredcites →https://doi.org/10.1126/science.1191175openalex-snapshot
Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial Enzyme
inferredcites →https://doi.org/10.1128/mcb.12.3.954openalex-snapshot
Induction of Mammary Tumors by Expression of Polyomavirus Middle T Oncogene: A Transgenic Mouse Model for Metastatic Disease
inferredcites →https://doi.org/10.1128/mmbr.00009-09openalex-snapshot
Lessons in Signaling and Tumorigenesis from Polyomavirus Middle T Antigen
inferredcites →https://doi.org/10.1146/annurev-pharmtox-011613-140007openalex-snapshot
Understanding and Modulating Mammalian-Microbial Communication for Improved Human Health
inferredcites →https://doi.org/10.1158/0008-5472.can-14-0385openalex-snapshot
Long-Chain Fatty Acid Analogues Suppress Breast Tumorigenesis and Progression
inferredcites →https://doi.org/10.1158/1940-6207.capr-12-0345openalex-snapshot
Chemoprevention Activity of Dipyridamole in the MMTV-PyMT Transgenic Mouse Model of Breast Cancer
inferredcites →https://doi.org/10.1158/1940-6207.capr-14-0110openalex-snapshot
Chemoprevention Activity of 25-Hydroxyvitamin D in the MMTV-PyMT Mouse Model of Breast Cancer
inferredcites →https://doi.org/10.1158/1940-6207.capr-17-0264openalex-snapshot
Chemoprevention of Preclinical Breast and Lung Cancer with the Bromodomain Inhibitor I-BET 762
inferredcites →https://doi.org/10.1186/1479-5876-10-253openalex-snapshot
Fecal microbial determinants of fecal and systemic estrogens and estrogen metabolites: a cross-sectional study
inferredcites →https://doi.org/10.1186/s12866-019-1483-xopenalex-snapshot
Gut microbial beta-glucuronidase and glycerol/diol dehydratase activity contribute to dietary heterocyclic amine biotransformation
inferredcites →https://doi.org/10.1210/jcem-43-3-497openalex-snapshot
Intestinal Metabolism of Estrogens1
inferredcites →https://doi.org/10.1371/journal.pone.0201370openalex-snapshot
Discriminating the earliest stages of mammary carcinoma using myoepithelial and proliferative markers
inferredcites →https://doi.org/10.2210/pdb6bjq/pdbopenalex-snapshot
Eubacterium eligens beta-glucuronidase bound to glucuronic acid
inferredcites →https://doi.org/10.2353/ajpath.2010.100595openalex-snapshot
Leptin Receptor Signaling Supports Cancer Cell Metabolism through Suppression of Mitochondrial Respiration in Vivo
inferredcites →https://doi.org/10.3109/00498254.2013.811314openalex-snapshot
Bacterial β-glucuronidase inhibition protects mice against enteropathy induced by indomethacin, ketoprofen or diclofenac: mode of action and pharmacokinetics
inferredcites →https://doi.org/10.3109/03009738409178470openalex-snapshot
Enterohepatic Recirculation of Oestriol Studied in Cholecystectomized and Non-cholecystectomized Menopausal Women
inferredcites →https://doi.org/10.3322/caac.21254openalex-snapshot
Cancer statistics, 2015
inferredcites →https://doi.org/10.3390/cancers7030828openalex-snapshot
High-Fat, High-Calorie Diet Enhances Mammary Carcinogenesis and Local Inflammation in MMTV-PyMT Mouse Model of Breast Cancer
inferredcites →https://doi.org/10.3758/bf03193146openalex-snapshot
G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences
inferredcites →https://doi.org/10.3758/brm.41.4.1149openalex-snapshot
Statistical power analyses using G*Power 3.1: Tests for correlation and regression analyses

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1016/j.bcp.2021.114566openalex-snapshot
Human gut bacterial β-glucuronidase inhibition: An emerging approach to manage medication therapy
inferred← citeshttps://doi.org/10.1016/j.biopha.2020.110203openalex-snapshot
Association between the microbiota and women’s cancers – Cause or consequences?
inferred← citeshttps://doi.org/10.1016/j.tim.2023.03.010openalex-snapshot
Microbial endocrinology: the mechanisms by which the microbiota influences host sex steroids
inferred← citeshttps://doi.org/10.3390/nu16060861openalex-snapshot
Investigating the Metabolism of Estrogens in Ligilactobacillus salivarius Strains Isolated from Human Milk and Vaginal Microbiota
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