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The periphery and the core properties explain the omnigenic model in the human interactome
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1007/s00439-010-0850-3openalex-snapshot
Association between colony-stimulating factor 1 receptor gene polymorphisms and asthma risk
inferredcites →https://doi.org/10.1016/0378-8733(78)90021-7openalex-snapshot
Centrality in social networks conceptual clarification
inferredcites →https://doi.org/10.1016/j.ajhg.2011.10.004openalex-snapshot
Abundant Pleiotropy in Human Complex Diseases and Traits
inferredcites →https://doi.org/10.1016/j.autrev.2014.10.008openalex-snapshot
Is vitamin D a player or not in the pathophysiology of autoimmune thyroid diseases?
inferredcites →https://doi.org/10.1016/j.cell.2015.09.053openalex-snapshot
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances
inferredcites →https://doi.org/10.1016/j.cell.2017.05.038openalex-snapshot
An Expanded View of Complex Traits: From Polygenic to Omnigenic
inferredcites →https://doi.org/10.1016/j.cell.2019.04.014openalex-snapshot
Trans Effects on Gene Expression Can Drive Omnigenic Inheritance
inferredcites →https://doi.org/10.1016/j.jaci.2008.06.030openalex-snapshot
Association of IL1RL1, IL18R1, and IL18RAP gene cluster polymorphisms with asthma and atopy
inferredcites →https://doi.org/10.1016/j.jaci.2009.11.018openalex-snapshot
Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions
inferredcites →https://doi.org/10.1016/j.physrep.2009.11.002openalex-snapshot
Community detection in graphs
inferredcites →https://doi.org/10.1016/s0140-6736(99)03425-xopenalex-snapshot
Association of CCR5 ▵32 with reduced risk of asthma
inferredcites →https://doi.org/10.1016/s0140-6736(99)03819-2openalex-snapshot
Down's syndrome screening in the UK in 1998
inferredcites →https://doi.org/10.1038/nature22366openalex-snapshot
Architecture of the human interactome defines protein communities and disease networks
inferredcites →https://doi.org/10.1038/nmeth.2728openalex-snapshot
Using networks to measure similarity between genes: association index selection
inferredcites →https://doi.org/10.1038/nrg2918openalex-snapshot
Network medicine: a network-based approach to human disease
inferredcites →https://doi.org/10.1038/sdata.2017.29openalex-snapshot
A standard database for drug repositioning
inferredcites →https://doi.org/10.1056/nejmoa0906312openalex-snapshot
A Large-Scale, Consortium-Based Genomewide Association Study of Asthma
inferredcites →https://doi.org/10.1073/pnas.0400054101openalex-snapshot
Defining and identifying communities in networks
inferredcites →https://doi.org/10.1073/pnas.0701722105openalex-snapshot
Network properties of genes harboring inherited disease mutations
inferredcites →https://doi.org/10.1093/bioinformatics/bti688openalex-snapshot
Interactome-transcriptome analysis reveals the high centrality of genes differentially expressed in lung cancer tissues
inferredcites →https://doi.org/10.1093/bioinformatics/btm254openalex-snapshot
GEOquery: a bridge between the Gene Expression Omnibus (GEO) and BioConductor
inferredcites →https://doi.org/10.1093/bioinformatics/btv297openalex-snapshot
GEO2Enrichr: browser extension and server app to extract gene sets from GEO and analyze them for biological functions
inferredcites →https://doi.org/10.1093/hmg/ddv001openalex-snapshot
A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma
inferredcites →https://doi.org/10.1093/jee/39.2.269openalex-snapshot
Individual Comparisons of Grouped Data by Ranking Methods
inferredcites →https://doi.org/10.1093/nar/gkh061openalex-snapshot
The Unified Medical Language System (UMLS): integrating biomedical terminology
inferredcites →https://doi.org/10.1093/nar/gki033openalex-snapshot
Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders
inferredcites →https://doi.org/10.1093/nar/gkj102openalex-snapshot
From genomics to chemical genomics: new developments in KEGG
inferredcites →https://doi.org/10.1093/nar/gks1055openalex-snapshot
The ConsensusPathDB interaction database: 2013 update
inferredcites →https://doi.org/10.1093/nar/gkt1229openalex-snapshot
The NHGRI GWAS Catalog, a curated resource of SNP-trait associations
inferredcites →https://doi.org/10.1093/nar/gku1204openalex-snapshot
The BioGRID interaction database: 2015 update
inferredcites →https://doi.org/10.1093/nar/gkw993openalex-snapshot
DrugCentral: online drug compendium
inferredcites →https://doi.org/10.1093/nar/gkx1037openalex-snapshot
DrugBank 5.0: a major update to the DrugBank database for 2018
inferredcites →https://doi.org/10.1097/hco.0000000000000158openalex-snapshot
Inflammation in cardiac injury, repair and regeneration
inferredcites →https://doi.org/10.1101/605451openalex-snapshot
A reference map of the human protein interactome
inferredcites →https://doi.org/10.1101/gr.118992.110openalex-snapshot
Prioritizing candidate disease genes by network-based boosting of genome-wide association data
inferredcites →https://doi.org/10.1103/physreve.75.027105openalex-snapshot
Generalizations of the clustering coefficient to weighted complex networks
inferredcites →https://doi.org/10.1111/all.12869openalex-snapshot
Identification of STOML2 as a putative novel asthma risk gene associated with IL6R
inferredcites →https://doi.org/10.1111/cea.12188openalex-snapshot
VEGFA variants are associated with pre-school lung function, but not neonatal lung function
inferredcites →https://doi.org/10.1111/joim.12239openalex-snapshot
Role of alpha‐1 antitrypsin in human health and disease
inferredcites →https://doi.org/10.1126/science.1257601openalex-snapshot
Uncovering disease-disease relationships through the incomplete interactome
inferredcites →https://doi.org/10.1136/jmg.2006.041376openalex-snapshot
Predicting disease genes using protein–protein interactions
inferredcites →https://doi.org/10.1146/annurev.biophys.37.032807.125924openalex-snapshot
Intrinsically Disordered Proteins in Human Diseases: Introducing the D 2 Concept
inferredcites →https://doi.org/10.1152/ajplung.00300.2009openalex-snapshot
A role for decorin in a murine model of allergen-induced asthma
inferredcites →https://doi.org/10.1186/1752-0509-6-92openalex-snapshot
HINT: High-quality protein interactomes and their applications in understanding human disease
inferredcites →https://doi.org/10.1186/gb-2004-5-10-r80openalex-snapshot
Bioconductor: open software development for computational biology and bioinformatics
inferredcites →https://doi.org/10.1186/gb-2012-13-6-r46openalex-snapshot
Highly interconnected genes in disease-specific networks are enriched for disease-associated polymorphisms
inferredcites →https://doi.org/10.1371/journal.pgen.1002170openalex-snapshot
Genome-Wide Association Study Identifies HLA-DP as a Susceptibility Gene for Pediatric Asthma in Asian Populations
inferredcites →https://doi.org/10.1371/journal.pone.0013894openalex-snapshot
Unifying Candidate Gene and GWAS Approaches in Asthma
inferredcites →https://doi.org/10.2202/1544-6115.1027openalex-snapshot
Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments
inferredcites →https://doi.org/10.2307/3033543openalex-snapshot
A Set of Measures of Centrality Based on Betweenness
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1093/bib/bbab169openalex-snapshot
The peripheral and core regions of virus-host network of COVID-19
inferred← citeshttps://doi.org/10.1186/s12931-022-01963-5openalex-snapshot
Protein interaction networks provide insight into fetal origins of chronic obstructive pulmonary disease
inferred← citeshttps://doi.org/10.3390/genes12071101openalex-snapshot
Unveiling the Pathogenesis of Psychiatric Disorders Using Network Models
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