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β-HPV 8E6 Dysregulates the Hippo Signaling Pathway and Induces Aneuploidy

https://doi.org/10.1101/760439
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Outgoing claims: the papers this work cites, builds on, or argues with.

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Evidence for the Association of Human Papillomavirus Infection and Cutaneous Squamous Cell Carcinoma in Immunocompetent Individuals
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Association Between β-Genus Human Papillomavirus and Cutaneous Squamous Cell Carcinoma in Immunocompetent Individuals—A Meta-analysis
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Heterogeneity of TERT promoter mutations status in squamous cell carcinomas of different anatomical sites
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Cytokinesis Failure Triggers Hippo Tumor Suppressor Pathway Activation
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The TEAD/TEF Family of Transcription Factor Scalloped Mediates Hippo Signaling in Organ Size Control
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The Hippo Signaling Pathway in Development and Cancer
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Tetraploidy, aneuploidy and cancer
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Prevalence and awareness of actinic keratosis: Barriers and opportunities
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p53: Guardian of ploidy
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Hippo Signaling in the Immune System
inferredcites →https://doi.org/10.1016/j.virol.2013.04.022openalex-snapshot
HPV 5 and 8 E6 expression reduces ATM protein levels and attenuates LINE-1 retrotransposition
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Beta genus papillomaviruses and skin cancer
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Carcinogenicity of human papillomaviruses
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Protein Lysine Acetylation by p300/CBP
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Gene Ontology: tool for the unification of biology
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TERT Promoter Mutations in Skin Cancer: The Effects of Sun Exposure and X-Irradiation
inferredcites →https://doi.org/10.1038/modpathol.2013.167openalex-snapshot
Mutations of the TERT promoter are common in basal cell carcinoma and squamous cell carcinoma
inferredcites →https://doi.org/10.1038/nature10137openalex-snapshot
Role of YAP/TAZ in mechanotransduction
inferredcites →https://doi.org/10.1038/nature11003openalex-snapshot
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
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Cross-species identification of genomic drivers of squamous cell carcinoma development across preneoplastic intermediates
inferredcites →https://doi.org/10.1038/nrc798openalex-snapshot
Papillomaviruses and cancer: from basic studies to clinical application
inferredcites →https://doi.org/10.1038/nrd4161openalex-snapshot
The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment
inferredcites →https://doi.org/10.1038/sj.onc.1210085openalex-snapshot
Direct evidence for the role of centrosomally localized p53 in the regulation of centrosome duplication
inferredcites →https://doi.org/10.1073/pnas.75.3.1537openalex-snapshot
Characterization of two types of human papillomaviruses in lesions of epidermodysplasia verruciformis
inferredcites →https://doi.org/10.1073/pnas.92.20.9363openalex-snapshot
A biomarker that identifies senescent human cells in culture and in aging skin in vivo.
inferredcites →https://doi.org/10.1083/jcb.200405089openalex-snapshot
Triggering p53 after cytokinesis failure
inferredcites →https://doi.org/10.1093/jb/mvr063openalex-snapshot
A cell-based assay to screen stimulators of the Hippo pathway reveals the inhibitory effect of dobutamine on the YAP-dependent gene transcription
inferredcites →https://doi.org/10.1093/nar/gkw1138openalex-snapshot
PANTHER version 11: expanded annotation data from Gene Ontology and Reactome pathways, and data analysis tool enhancements
inferredcites →https://doi.org/10.1093/nar/gkw879openalex-snapshot
The Papillomavirus Episteme: a major update to the papillomavirus sequence database
inferredcites →https://doi.org/10.1093/nar/gky1055openalex-snapshot
The Gene Ontology Resource: 20 years and still GOing strong
inferredcites →https://doi.org/10.1097/00001622-200001000-00014openalex-snapshot
Aneuploidy and cancer
inferredcites →https://doi.org/10.1097/00042728-200608000-00010openalex-snapshot
Frequency and Cost of Actinic Keratosis Treatment
inferredcites →https://doi.org/10.1099/vir.0.012872-0openalex-snapshot
Spontaneous tumour development in human papillomavirus type 8 E6 transgenic mice and rapid induction by UV-light exposure and wounding
inferredcites →https://doi.org/10.1101/369447openalex-snapshot
High-risk human papillomaviruses down-regulate expression of the Ste20 family kinase MST1 to inhibit the Hippo pathway and promote transformation
inferredcites →https://doi.org/10.1101/gad.1664408openalex-snapshot
TEAD mediates YAP-dependent gene induction and growth control
inferredcites →https://doi.org/10.1111/j.0022-202x.2005.23635.xopenalex-snapshot
Human Papillomavirus Gene Expression in Cutaneous Squamous Cell Carcinomas from Immunosuppressed and Immunocompetent Individuals
inferredcites →https://doi.org/10.1111/j.0022-202x.2005.23733.xopenalex-snapshot
Human Papillomavirus-DNA Loads in Actinic Keratoses Exceed those in Non-Melanoma Skin Cancers
inferredcites →https://doi.org/10.1111/j.1524-4725.2012.02558.xopenalex-snapshot
Cutaneous Squamous Cell Carcinoma and Human Papillomavirus: Is There an Association?
inferredcites →https://doi.org/10.1126/science.1224922openalex-snapshot
An Immunosurveillance Mechanism Controls Cancer Cell Ploidy
inferredcites →https://doi.org/10.1126/scisignal.2004088openalex-snapshot
Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
inferredcites →https://doi.org/10.1128/jvi.00250-06openalex-snapshot
The E6 Protein of the Cutaneous Human Papillomavirus Type 8 Can Stimulate the Viral Early and Late Promoters by Distinct Mechanisms
inferredcites →https://doi.org/10.1128/jvi.00902-08openalex-snapshot
E6 Proteins from Multiple Human Betapapillomavirus Types Degrade Bak and Protect Keratinocytes from Apoptosis after UVB Irradiation
inferredcites →https://doi.org/10.1128/jvi.01338-08openalex-snapshot
Intrafamilial Transmission and Family-Specific Spectra of Cutaneous Betapapillomaviruses
inferredcites →https://doi.org/10.1128/jvi.02172-12openalex-snapshot
Comprehensive Analysis of Host Cellular Interactions with Human Papillomavirus E6 Proteins Identifies New E6 Binding Partners and Reflects Viral Diversity
inferredcites →https://doi.org/10.1128/jvi.02527-12openalex-snapshot
The Human Papillomavirus Type 8 E6 Protein Interferes with NOTCH Activation during Keratinocyte Differentiation
inferredcites →https://doi.org/10.1128/jvi.03808-13openalex-snapshot
Beta Human Papillomavirus E6 Expression Inhibits Stabilization of p53 and Increases Tolerance of Genomic Instability
inferredcites →https://doi.org/10.1128/mcb.20.4.1436-1447.2000openalex-snapshot
Human Keratinocytes That Express hTERT and Also Bypass a p16 INK4a -Enforced Mechanism That Limits Life Span Become Immortal yet Retain Normal Growth and Differentiation Characteristics
inferredcites →https://doi.org/10.1136/jcp.52.4.249openalex-snapshot
Human papillomavirus and the development of non-melanoma skin cancer.
inferredcites →https://doi.org/10.1146/annurev-cellbio-092910-154234openalex-snapshot
The Causes and Consequences of Polyploidy in Normal Development and Cancer
inferredcites →https://doi.org/10.1152/physrev.00005.2014openalex-snapshot
The Biology of YAP/TAZ: Hippo Signaling and Beyond
inferredcites →https://doi.org/10.1158/0008-5472.can-04-3263openalex-snapshot
Development of Skin Tumors in Mice Transgenic for Early Genes of Human Papillomavirus Type 8
inferredcites →https://doi.org/10.1158/0008-5472.can-10-1307openalex-snapshot
Cutaneous Papillomavirus E6 Proteins Must Interact with p300 and Block p53-Mediated Apoptosis for Cellular Immortalization and Tumorigenesis
inferredcites →https://doi.org/10.1158/1078-0432.ccr-14-1768openalex-snapshot
Mutational Landscape of Aggressive Cutaneous Squamous Cell Carcinoma
inferredcites →https://doi.org/10.1158/1078-0432.ccr-14-1773openalex-snapshot
Genomic Analysis of Metastatic Cutaneous Squamous Cell Carcinoma
inferredcites →https://doi.org/10.1158/2159-8290.cd-12-0095openalex-snapshot
The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data
inferredcites →https://doi.org/10.1186/1471-2105-10-48openalex-snapshot
GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists
inferredcites →https://doi.org/10.1242/jcs.114.13.2363openalex-snapshot
p300/CBP proteins: HATs for transcriptional bridges and scaffolds
inferredcites →https://doi.org/10.1242/jcs.214742openalex-snapshot
Chromosomes trapped in micronuclei are liable to segregation errors
inferredcites →https://doi.org/10.1371/journal.pcbi.0030039openalex-snapshot
Discovering Motifs in Ranked Lists of DNA Sequences
inferredcites →https://doi.org/10.1371/journal.pone.0044010openalex-snapshot
Inherited MST1 Deficiency Underlies Susceptibility to EV-HPV Infections
inferredcites →https://doi.org/10.1371/journal.pone.0080354openalex-snapshot
TERT Promoter Mutations Are Frequent in Cutaneous Basal Cell Carcinoma and Squamous Cell Carcinoma
inferredcites →https://doi.org/10.1371/journal.pone.0149859openalex-snapshot
Sterile α Motif Domain Containing 9 Is a Novel Cellular Interacting Partner to Low-Risk Type Human Papillomavirus E6 Proteins
inferredcites →https://doi.org/10.1371/journal.ppat.1002125openalex-snapshot
E6 and E7 from Beta Hpv38 Cooperate with Ultraviolet Light in the Development of Actinic Keratosis-Like Lesions and Squamous Cell Carcinoma in Mice
inferredcites →https://doi.org/10.1371/journal.ppat.1002211openalex-snapshot
Beta-HPV 5 and 8 E6 Promote p300 Degradation by Blocking AKT/p300 Association
inferredcites →https://doi.org/10.1371/journal.ppat.1002807openalex-snapshot
HPV 5 and 8 E6 Abrogate ATR Activity Resulting in Increased Persistence of UVB Induced DNA Damage
inferredcites →https://doi.org/10.1371/journal.ppat.1004687openalex-snapshot
β-HPV 5 and 8 E6 Disrupt Homology Dependent Double Strand Break Repair by Attenuating BRCA1 and BRCA2 Expression and Foci Formation
inferredcites →https://doi.org/10.1371/journal.ppat.1006171openalex-snapshot
Cutaneous HPV8 and MmuPV1 E6 Proteins Target the NOTCH and TGF-β Tumor Suppressors to Inhibit Differentiation and Sustain Keratinocyte Proliferation
inferredcites →https://doi.org/10.15252/embr.201439245openalex-snapshot
Senescence and apoptosis: dueling or complementary cell fates?
inferredcites →https://doi.org/10.15252/emmm.201404976openalex-snapshot
The Hippo/YAP pathway interacts with EGFR signaling and HPV oncoproteins to regulate cervical cancer progression
inferredcites →https://doi.org/10.18632/oncotarget.11069openalex-snapshot
Deletion of epidermal Rac1 inhibits HPV-8 induced skin papilloma formation and facilitates HPV-8- and UV-light induced skin carcinogenesis
inferredcites →https://doi.org/10.3389/fimmu.2018.00149openalex-snapshot
The Role of Mst1 in Lymphocyte Homeostasis and Function
inferredcites →https://doi.org/10.3791/50203openalex-snapshot
Chromosome Preparation From Cultured Cells
inferredcites →https://doi.org/10.3791/57653openalex-snapshot
Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy
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