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Xmas ESC: A new female embryonic stem cell system that reveals the BAF complex as a key regulator of the establishment of X chromosome inactivation

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Widespread recombinase expression using FLPeR (Flipper) mice
inferredcites →https://doi.org/10.1002/gene.1016openalex-snapshot
An X‐linked GFP transgene reveals unexpected paternal X‐chromosome activity in trophoblastic giant cells of the mouse placenta
inferredcites →https://doi.org/10.1002/j.1460-2075.1996.tb00921.xopenalex-snapshot
Purification and biochemical heterogeneity of the mammalian SWI‐SNF complex.
inferredcites →https://doi.org/10.1006/dbio.1996.0333openalex-snapshot
X-Inactivation and Histone H4 Acetylation in Embryonic Stem Cells
inferredcites →https://doi.org/10.1006/dbio.2000.9823openalex-snapshot
X Inactivation in the Mouse Embryo Deficient for Dnmt1: Distinct Effect of Hypomethylation on Imprinted and Random X Inactivation
inferredcites →https://doi.org/10.1007/978-1-4939-7481-8_14openalex-snapshot
Nucleosome Occupancy and Methylome Sequencing (NOMe-seq)
inferredcites →https://doi.org/10.1007/978-1-59745-406-3_18openalex-snapshot
Combined Immunofluorescence, RNA Fluorescent In Situ Hybridization, and DNA Fluorescent In Situ Hybridization to Study Chromatin Changes, Transcriptional Activity, Nuclear Organization, and X-Chromosome Inactivation
inferredcites →https://doi.org/10.1007/s00335-013-9451-5openalex-snapshot
No evidence for cumulative effects in a Dnmt3b hypomorph across multiple generations
inferredcites →https://doi.org/10.1007/s00335-014-9516-0openalex-snapshot
The first mouse mutants of D14Abb1e (Fam208a) show that it is critical for early development
inferredcites →https://doi.org/10.1007/s12041-015-0574-1openalex-snapshot
X-chromosome inactivation and escape
inferredcites →https://doi.org/10.1016/0014-4827(82)90072-6openalex-snapshot
5-Azacytidine-induced re-expression of alleles on the inactive X chromosome in a hybrid mouse cell line
inferredcites →https://doi.org/10.1016/0092-8674(92)90520-mopenalex-snapshot
The human XIST gene: Analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus
inferredcites →https://doi.org/10.1016/0092-8674(92)90611-fopenalex-snapshot
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
inferredcites →https://doi.org/10.1016/j.cell.2008.05.031openalex-snapshot
An RNAi Screen of Chromatin Proteins Identifies Tip60-p400 as a Regulator of Embryonic Stem Cell Identity
inferredcites →https://doi.org/10.1016/j.cell.2012.03.026openalex-snapshot
The Transcriptional and Epigenomic Foundations of Ground State Pluripotency
inferredcites →https://doi.org/10.1016/j.cell.2014.11.040openalex-snapshot
X Chromosome Reactivation Dynamics Reveal Stages of Reprogramming to Pluripotency
inferredcites →https://doi.org/10.1016/j.cell.2015.03.025openalex-snapshot
Systematic Discovery of Xist RNA Binding Proteins
inferredcites →https://doi.org/10.1016/j.cell.2018.09.032openalex-snapshot
Modular Organization and Assembly of SWI/SNF Family Chromatin Remodeling Complexes
inferredcites →https://doi.org/10.1016/j.cell.2018.11.041openalex-snapshot
The Implication of Early Chromatin Changes in X Chromosome Inactivation
inferredcites →https://doi.org/10.1016/j.celrep.2015.06.053openalex-snapshot
A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing
inferredcites →https://doi.org/10.1016/j.celrep.2015.06.067openalex-snapshot
Identification of Spen as a Crucial Factor for Xist Function through Forward Genetic Screening in Haploid Embryonic Stem Cells
inferredcites →https://doi.org/10.1016/j.celrep.2017.01.008openalex-snapshot
Gender Differences in Global but Not Targeted Demethylation in iPSC Reprogramming
inferredcites →https://doi.org/10.1016/j.celrep.2018.10.044openalex-snapshot
Smchd1 Targeting to the Inactive X Is Dependent on the Xist-HnrnpK-PRC1 Pathway
inferredcites →https://doi.org/10.1016/j.devcel.2004.10.005openalex-snapshot
Polycomb Group Proteins Ring1A/B Link Ubiquitylation of Histone H2A to Heritable Gene Silencing and X Inactivation
inferredcites →https://doi.org/10.1016/j.devcel.2010.08.006openalex-snapshot
The Matrix Protein hnRNP U Is Required for Chromosomal Localization of Xist RNA
inferredcites →https://doi.org/10.1016/j.devcel.2012.06.011openalex-snapshot
Smchd1-Dependent and -Independent Pathways Determine Developmental Dynamics of CpG Island Methylation on the Inactive X Chromosome
inferredcites →https://doi.org/10.1016/j.jmb.2018.05.031openalex-snapshot
Genome-Wide RNAi Screen Identify Melanoma-Associated Antigen Mageb3 Involved in X Chromosome Inactivation
inferredcites →https://doi.org/10.1016/j.molcel.2006.11.017openalex-snapshot
Identification of a Ctcf Cofactor, Yy1, for the X Chromosome Binary Switch
inferredcites →https://doi.org/10.1016/j.molcel.2014.01.002openalex-snapshot
Jarid2 Is Implicated in the Initial Xist-Induced Targeting of PRC2 to the Inactive X Chromosome
inferredcites →https://doi.org/10.1016/j.stem.2013.06.002openalex-snapshot
Whole-Genome Bisulfite Sequencing of Two Distinct Interconvertible DNA Methylomes of Mouse Embryonic Stem Cells
inferredcites →https://doi.org/10.1016/j.stem.2013.11.022openalex-snapshot
The Two Active X Chromosomes in Female ESCs Block Exit from the Pluripotent State by Modulating the ESC Signaling Network
inferredcites →https://doi.org/10.1016/j.stem.2017.03.002openalex-snapshot
DUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells
inferredcites →https://doi.org/10.1016/j.stemcr.2016.01.014openalex-snapshot
A Versatile Strategy for Isolating a Highly Enriched Population of Intestinal Stem Cells
inferredcites →https://doi.org/10.1016/j.stemcr.2018.03.019openalex-snapshot
X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs
inferredcites →https://doi.org/10.1016/j.stemcr.2018.12.004openalex-snapshot
X-Chromosome Dosage Modulates Multiple Molecular and Cellular Properties of Mouse Pluripotent Stem Cells Independently of Global DNA Methylation Levels
inferredcites →https://doi.org/10.1016/j.ydbio.2007.12.024openalex-snapshot
SRG3, a core component of mouse SWI/SNF complex, is essential for extra-embryonic vascular development
inferredcites →https://doi.org/10.1016/s0092-8674(01)00598-0openalex-snapshot
Methylation of Histone H3 at Lys-9 Is an Early Mark on the X Chromosome during X Inactivation
inferredcites →https://doi.org/10.1016/s0960-9822(02)00660-7openalex-snapshot
Histone H3 Lysine 9 Methylation Occurs Rapidly at the Onset of Random X Chromosome Inactivation
inferredcites →https://doi.org/10.1016/s0960-9822(02)00892-8openalex-snapshot
Mitotically Stable Association of Polycomb Group Proteins Eed and Enx1 with the Inactive X Chromosome in Trophoblast Stem Cells
inferredcites →https://doi.org/10.1016/s0960-9822(99)80151-1openalex-snapshot
X-chromosome inactivation
inferredcites →https://doi.org/10.1016/s1097-2765(00)00127-1openalex-snapshot
A Brg1 Null Mutation in the Mouse Reveals Functional Differences among Mammalian SWI/SNF Complexes
inferredcites →https://doi.org/10.1016/s1097-2765(00)80248-8openalex-snapshot
A Shift from Reversible to Irreversible X Inactivation Is Triggered during ES Cell Differentiation
inferredcites →https://doi.org/10.1016/s1534-5807(03)00068-6openalex-snapshot
Establishment of Histone H3 Methylation on the Inactive X Chromosome Requires Transient Recruitment of Eed-Enx1 Polycomb Group Complexes
inferredcites →https://doi.org/10.1038/256640a0openalex-snapshot
Preferential inactivation of the paternally derived X chromosome in the extraembryonic membranes of the mouse
inferredcites →https://doi.org/10.1038/309255a0openalex-snapshot
Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines
inferredcites →https://doi.org/10.1038/326292a0openalex-snapshot
HPRT-deficient (Lesch–Nyhan) mouse embryos derived from germline colonization by cultured cells
inferredcites →https://doi.org/10.1038/351329a0openalex-snapshot
Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome
inferredcites →https://doi.org/10.1038/893openalex-snapshot
Non-invasive sexing of preimplantation stage mammalian embryos
inferredcites →https://doi.org/10.1038/nature06968openalex-snapshot
The ground state of embryonic stem cell self-renewal
inferredcites →https://doi.org/10.1038/nature11049openalex-snapshot
Spatial partitioning of the regulatory landscape of the X-inactivation centre
inferredcites →https://doi.org/10.1038/nature14443openalex-snapshot
The Xist lncRNA interacts with SHARP to silence transcription through HDAC3
inferredcites →https://doi.org/10.1038/nature18589openalex-snapshot
Structural organization of the inactive X chromosome in the mouse
inferredcites →https://doi.org/10.1038/nature23274openalex-snapshot
Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells
inferredcites →https://doi.org/10.1038/nature23286openalex-snapshot
Derivation of ground-state female ES cells maintaining gamete-derived DNA methylation
inferredcites →https://doi.org/10.1038/nbt.3270openalex-snapshot
Transient acquisition of pluripotency during somatic cell transdifferentiation with iPSC reprogramming factors
inferredcites →https://doi.org/10.1038/ncomms13661openalex-snapshot
Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2
inferredcites →https://doi.org/10.1038/ncomms5878openalex-snapshot
A prominent and conserved role for YY1 in Xist transcriptional activation
inferredcites →https://doi.org/10.1038/ng.142openalex-snapshot
SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation
inferredcites →https://doi.org/10.1038/ng1663openalex-snapshot
Global hypomethylation of the genome in XX embryonic stem cells
inferredcites →https://doi.org/10.1038/ng2031openalex-snapshot
Modifiers of epigenetic reprogramming show paternal effects in the mouse
inferredcites →https://doi.org/10.1038/ng787openalex-snapshot
Differentially methylated forms of histone H3 show unique association patterns with inactive human X chromosomes
inferredcites →https://doi.org/10.1038/ng789openalex-snapshot
Histone H3 lysine 9 methylation is an epigenetic imprint of facultative heterochromatin
inferredcites →https://doi.org/10.1038/nmeth.1923openalex-snapshot
Fast gapped-read alignment with Bowtie 2
inferredcites →https://doi.org/10.1038/nmeth.2019openalex-snapshot
Fiji: an open-source platform for biological-image analysis
inferredcites →https://doi.org/10.1038/nmeth.3317openalex-snapshot
HISAT: a fast spliced aligner with low memory requirements
inferredcites →https://doi.org/10.1038/nrg.2017.17openalex-snapshot
The X chromosome in space
inferredcites →https://doi.org/10.1038/nsmb.1877openalex-snapshot
The A-repeat links ASF/SF2-dependent Xist RNA processing with random choice during X inactivation
inferredcites →https://doi.org/10.1038/s41592-018-0104-1openalex-snapshot
Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells
inferredcites →https://doi.org/10.1038/s41594-018-0111-zopenalex-snapshot
Smchd1 regulates long-range chromatin interactions on the inactive X chromosome and at Hox clusters
inferredcites →https://doi.org/10.1038/s41594-018-0176-8openalex-snapshot
Xist RNA antagonizes the SWI/SNF chromatin remodeler BRG1 on the inactive X chromosome
inferredcites →https://doi.org/10.1038/sj.emboj.7601187openalex-snapshot
Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing
inferredcites →https://doi.org/10.1073/pnas.0409375102openalex-snapshot
An N -ethyl- N -nitrosourea screen for genes involved in variegation in the mouse
inferredcites →https://doi.org/10.1073/pnas.0812889106openalex-snapshot
An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency
inferredcites →https://doi.org/10.1073/pnas.1107616108openalex-snapshot
Diverse factors are involved in maintaining X chromosome inactivation
inferredcites →https://doi.org/10.1073/pnas.1413620111openalex-snapshot
Genetic and pharmacological reactivation of the mammalian inactive X chromosome
inferredcites →https://doi.org/10.1073/pnas.1617597113openalex-snapshot
A high-throughput small molecule screen identifies synergism between DNA methylation and Aurora kinase pathways for X reactivation
inferredcites →https://doi.org/10.1073/pnas.1621356114openalex-snapshot
Screen for reactivation of MeCP2 on the inactive X chromosome identifies the BMP/TGF-β superfamily as a regulator of XIST expression
inferredcites →https://doi.org/10.1073/pnas.78.5.3093openalex-snapshot
X chromosome reactivation in oocytes of Mus caroli.
inferredcites →https://doi.org/10.1073/pnas.90.18.8424openalex-snapshot
Derivation of completely cell culture-derived mice from early-passage embryonic stem cells.
inferredcites →https://doi.org/10.1074/jbc.c400493200openalex-snapshot
Ring1b-mediated H2A Ubiquitination Associates with Inactive X Chromosomes and Is Involved in Initiation of X Inactivation
inferredcites →https://doi.org/10.1074/jbc.m806061200openalex-snapshot
BRD7, a Novel PBAF-specific SWI/SNF Subunit, Is Required for Target Gene Activation and Repression in Embryonic Stem Cells
inferredcites →https://doi.org/10.1083/jcb.153.4.773openalex-snapshot
Synergism of Xist Rna, DNA Methylation, and Histone Hypoacetylation in Maintaining X Chromosome Inactivation
inferredcites →https://doi.org/10.1083/jcb.200409026openalex-snapshot
Developmentally regulated alterations in Polycomb repressive complex 1 proteins on the inactive X chromosome
inferredcites →https://doi.org/10.1089/cell.2010.0075openalex-snapshot
SAF-A Has a Role in Transcriptional Regulation of Oct4 in ES Cells Through Promoter Binding
inferredcites →https://doi.org/10.1093/bioinformatics/bti270openalex-snapshot
Use of within-array replicate spots for assessing differential expression in microarray experiments
inferredcites →https://doi.org/10.1093/bioinformatics/btp053openalex-snapshot
Testing significance relative to a fold-change threshold is a TREAT
inferredcites →https://doi.org/10.1093/bioinformatics/btp120openalex-snapshot
TopHat: discovering splice junctions with RNA-Seq
inferredcites →https://doi.org/10.1093/bioinformatics/btp616openalex-snapshot
edgeR : a Bioconductor package for differential expression analysis of digital gene expression data
inferredcites →https://doi.org/10.1093/bioinformatics/btr167openalex-snapshot
Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications
inferredcites →https://doi.org/10.1093/intimm/5.8.957openalex-snapshot
Targeted disruption of the MHC class II Aa gene in C57BL/6 mice
inferredcites →https://doi.org/10.1093/molehr/gaq042openalex-snapshot
Sex-related physiology of the preimplantation embryo
inferredcites →https://doi.org/10.1093/nar/gks042openalex-snapshot
Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation
inferredcites →https://doi.org/10.1093/nar/gkv007openalex-snapshot
limma powers differential expression analyses for RNA-sequencing and microarray studies
inferredcites →https://doi.org/10.1093/oxfordjournals.humrep.a137889openalex-snapshot
Blastocysts prepare for the race to be male
inferredcites →https://doi.org/10.1095/biolreprod.114.124958openalex-snapshot
Generation of Fully Pluripotent Female Murine-Induced Pluripotent Stem Cells1
inferredcites →https://doi.org/10.1098/rstb.1995.0159openalex-snapshot
The genetic basis of XX-XY differences present before gonadal sex differentiation in the mouse
inferredcites →https://doi.org/10.1098/rstb.2016.0366openalex-snapshot
X-chromosome dosage as a modulator of pluripotency, signalling and differentiation?
inferredcites →https://doi.org/10.1101/519207openalex-snapshot
Single cell multi-omics profiling reveals a hierarchical epigenetic landscape during mammalian germ layer specification
inferredcites →https://doi.org/10.1101/cshperspect.a017939openalex-snapshot
The Use of Mouse Models to Study Epigenetics
inferredcites →https://doi.org/10.1101/cshperspect.a019406openalex-snapshot
Dosage Compensation in Mammals
inferredcites →https://doi.org/10.1101/gad.10.17.2117openalex-snapshot
Diversity and specialization of mammalian SWI/SNF complexes.
inferredcites →https://doi.org/10.1101/gad.633311openalex-snapshot
The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA
inferredcites →https://doi.org/10.1101/gr.143008.112openalex-snapshot
Genome-wide mapping of nucleosome positioning and DNA methylation within individual DNA molecules
inferredcites →https://doi.org/10.1101/gr.163485.113openalex-snapshot
Reconfiguration of nucleosome-depleted regions at distal regulatory elements accompanies DNA methylation of enhancers and insulators in cancer
inferredcites →https://doi.org/10.1101/gr.201954.115openalex-snapshot
Single-cell analyses of X Chromosome inactivation dynamics and pluripotency during differentiation
inferredcites →https://doi.org/10.1126/science.1084274openalex-snapshot
Role of Histone H3 Lysine 27 Methylation in X Inactivation
inferredcites →https://doi.org/10.1126/science.6164095openalex-snapshot
Reactivation of an Inactive Human X Chromosome: Evidence for X Inactivation by DNA Methylation
inferredcites →https://doi.org/10.1126/science.aab2276openalex-snapshot
A comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation
inferredcites →https://doi.org/10.1182/blood-2014-10-603969openalex-snapshot
Jarid2 regulates hematopoietic stem cell function by acting with polycomb repressive complex 2
inferredcites →https://doi.org/10.1186/1756-8935-3-17openalex-snapshot
Dynamic instability of genomic methylation patterns in pluripotent stem cells
inferredcites →https://doi.org/10.1186/1756-8935-7-12openalex-snapshot
The Mbd1-Atf7ip-Setdb1 pathway contributes to the maintenance of X chromosome inactivation
inferredcites →https://doi.org/10.1186/gb-2008-9-12-r182openalex-snapshot
A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development
inferredcites →https://doi.org/10.1186/gb-2010-11-11-r111openalex-snapshot
Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic noise
inferredcites →https://doi.org/10.1186/gb-2013-14-9-r96openalex-snapshot
An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse
inferredcites →https://doi.org/10.1186/gb-2014-15-2-r29openalex-snapshot
voom: precision weights unlock linear model analysis tools for RNA-seq read counts
inferredcites →https://doi.org/10.1186/s13059-015-0728-8openalex-snapshot
Bipartite structure of the inactive mouse X chromosome
inferredcites →https://doi.org/10.1186/s13072-015-0034-4openalex-snapshot
A high-throughput screen of inactive X chromosome reactivation identifies the enhancement of DNA demethylation by 5-aza-2′-dC upon inhibition of ribonucleotide reductase
inferredcites →https://doi.org/10.1186/s13072-016-0064-6openalex-snapshot
Setdb1-mediated H3K9 methylation is enriched on the inactive X and plays a role in its epigenetic silencing
inferredcites →https://doi.org/10.1214/16-aoas920openalex-snapshot
Robust hyperparameter estimation protects against hypervariable genes and improves power to detect differential expression
inferredcites →https://doi.org/10.1242/dev.068320openalex-snapshot
Fifty years of X-inactivation research
inferredcites →https://doi.org/10.1242/dev.120.10.2925openalex-snapshot
X-chromosome activity of the mouse primordial germ cells revealed by the expression of an X-linked lacZ transgene
inferredcites →https://doi.org/10.1242/dev.121061openalex-snapshot
Reactivation of the inactive X chromosome and post-transcriptional reprogramming of Xist in iPSCs
inferredcites →https://doi.org/10.1242/dev.173146openalex-snapshot
Defined conditions for propagation and manipulation of mouse embryonic stem cells
inferredcites →https://doi.org/10.1242/dev.63.1.75openalex-snapshot
X-chromosome activity in foetal germ cells of the mouse
inferredcites →https://doi.org/10.1242/jcs.154294openalex-snapshot
Reactivation of inactive X chromosome and post-transcriptional reprogramming of Xist in induced pluripotent stem cells
inferredcites →https://doi.org/10.12688/f1000research.12544.1openalex-snapshot
Easy and efficient ensemble gene set testing with EGSEA
inferredcites →https://doi.org/10.12688/f1000research.9037.1openalex-snapshot
SNPsplit: Allele-specific splitting of alignments between genomes with known SNP genotypes
inferredcites →https://doi.org/10.12688/f1000research.9037.2openalex-snapshot
SNPsplit: Allele-specific splitting of alignments between genomes with known SNP genotypes
inferredcites →https://doi.org/10.1371/journal.pbio.0060093openalex-snapshot
Polycomb Repressive Complex 2 (PRC2) Restricts Hematopoietic Stem Cell Activity
inferredcites →https://doi.org/10.1371/journal.pcbi.1003118openalex-snapshot
Software for Computing and Annotating Genomic Ranges
inferredcites →https://doi.org/10.1534/g3.112.004036openalex-snapshot
A Forward Genetic Screen Identifies Eukaryotic Translation Initiation Factor 3, Subunit H (eIF3h), as an Enhancer of Variegation in the Mouse
inferredcites →https://doi.org/10.1634/stemcells.2008-0710openalex-snapshot
SWI/SNF-Brg1 Regulates Self-Renewal and Occupies Core Pluripotency-Related Genes in Embryonic Stem Cells
inferredcites →https://doi.org/10.1634/stemcells.2008-1075openalex-snapshot
Induced Pluripotent Stem Cell Generation Using a Single Lentiviral Stem Cell Cassette
inferredcites →https://doi.org/10.3791/51728openalex-snapshot
Cell Surface Marker Mediated Purification of iPS Cell Intermediates from a Reprogrammable Mouse Model

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.3390/cells9122706openalex-snapshot
New Insights into X-Chromosome Reactivation during Reprogramming to Pluripotency
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