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Dopamine Promotes Cognitive Effort by Biasing the Benefits Versus Costs of Cognitive Work

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/wcs.1401openalex-snapshot
The costs and benefits of brain dopamine for cognitive control
inferredcites →https://doi.org/10.1007/bf00430753openalex-snapshot
Prolactin response following intravenous and oral sulpiride in healthy human subjects in relation to sulpiride concentrations
inferredcites →https://doi.org/10.1007/s00213-006-0502-4openalex-snapshot
Tonic dopamine: opportunity costs and the control of response vigor
inferredcites →https://doi.org/10.1016/j.beproc.2016.02.008openalex-snapshot
The pharmacology of effort-related choice behavior: Dopamine, depression, and individual differences
inferredcites →https://doi.org/10.1016/j.biopsych.2011.03.028openalex-snapshot
Inverted-U–Shaped Dopamine Actions on Human Working Memory and Cognitive Control
inferredcites →https://doi.org/10.1016/j.biopsych.2014.09.013openalex-snapshot
The Cognition-Enhancing Effects of Psychostimulants Involve Direct Action in the Prefrontal Cortex
inferredcites →https://doi.org/10.1016/j.cobeha.2015.05.007openalex-snapshot
The cost of dopamine for dynamic cognitive control
inferredcites →https://doi.org/10.1016/j.cobeha.2017.12.011openalex-snapshot
Dopamine and proximity in motivation and cognitive control
inferredcites →https://doi.org/10.1016/j.cortex.2018.12.001openalex-snapshot
Voluntary modulation of saccadic peak velocity associated with individual differences in motivation
inferredcites →https://doi.org/10.1016/j.cub.2015.05.038openalex-snapshot
Reward Pays the Cost of Noise Reduction in Motor and Cognitive Control
inferredcites →https://doi.org/10.1016/j.ejphar.2006.01.014openalex-snapshot
Dopamine D3 receptor modulation of dopamine efflux in the rat nucleus accumbens
inferredcites →https://doi.org/10.1016/j.neubiorev.2003.08.013openalex-snapshot
Serum and brain concentrations of methylphenidate: implications for use and abuse
inferredcites →https://doi.org/10.1016/j.neuroimage.2011.11.073openalex-snapshot
Aberrant reward processing in Parkinson's disease is associated with dopamine cell loss
inferredcites →https://doi.org/10.1016/j.neuron.2015.12.029openalex-snapshot
Dopamine Does Double Duty in Motivating Cognitive Effort
inferredcites →https://doi.org/10.1016/j.neuropharm.2018.04.025openalex-snapshot
Dissociable contributions of dorsal and ventral striatal regions on a rodent cost/benefit decision-making task requiring cognitive effort
inferredcites →https://doi.org/10.1016/j.neuropsychologia.2014.05.023openalex-snapshot
Greater striatal responses to medication in Parkinson׳s disease are associated with better task-switching but worse reward performance
inferredcites →https://doi.org/10.1037/0033-295x.108.2.370openalex-snapshot
Multialternative decision field theory: A dynamic connectionst model of decision making.
inferredcites →https://doi.org/10.1037/0735-7044.120.3.497openalex-snapshot
A mechanistic account of striatal dopamine function in human cognition: Psychopharmacological studies with cabergoline and haloperidol.
inferredcites →https://doi.org/10.1037/a0020198openalex-snapshot
Decision making and the avoidance of cognitive demand.
inferredcites →https://doi.org/10.1037/a0035813openalex-snapshot
Eye tracking and pupillometry are indicators of dissociable latent decision processes.
inferredcites →https://doi.org/10.1037/a0037015openalex-snapshot
Opponent actor learning (OpAL): Modeling interactive effects of striatal dopamine on reinforcement learning and choice incentive.
inferredcites →https://doi.org/10.1037/xge0000523openalex-snapshot
Catecholaminergic modulation of the avoidance of cognitive control.
inferredcites →https://doi.org/10.1038/jcbfm.1983.1openalex-snapshot
Graphical Evaluation of Blood-to-Brain Transfer Constants from Multiple-Time Uptake Data
inferredcites →https://doi.org/10.1038/mp.2010.97openalex-snapshot
Motivation deficit in ADHD is associated with dysfunction of the dopamine reward pathway
inferredcites →https://doi.org/10.1038/nn.2635openalex-snapshot
Visual fixations and the computation and comparison of value in simple choice
inferredcites →https://doi.org/10.1038/nn1150openalex-snapshot
Gaze bias both reflects and influences preference
inferredcites →https://doi.org/10.1038/npp.2012.30openalex-snapshot
Sensitivity to Cognitive Effort Mediates Psychostimulant Effects on a Novel Rodent Cost/Benefit Decision-Making Task
inferredcites →https://doi.org/10.1038/npp.2014.285openalex-snapshot
Dopamine Antagonism Decreases Willingness to Expend Physical, But Not Cognitive, Effort: A Comparison of Two Rodent Cost/Benefit Decision-Making Tasks
inferredcites →https://doi.org/10.1038/npp.2014.84openalex-snapshot
Role of Dopamine D2 Receptors in Human Reinforcement Learning
inferredcites →https://doi.org/10.1038/srep16880openalex-snapshot
The role of cognitive effort in subjective reward devaluation and risky decision-making
inferredcites →https://doi.org/10.1073/pnas.1507610113openalex-snapshot
Regional specialization within the human striatum for diverse psychological functions
inferredcites →https://doi.org/10.1093/brain/awy341openalex-snapshot
Dopamine restores cognitive motivation in Parkinson’s disease
inferredcites →https://doi.org/10.1093/cercor/bhs344openalex-snapshot
Establishing the Dopamine Dependency of Human Striatal Signals During Reward and Punishment Reversal Learning
inferredcites →https://doi.org/10.1093/cercor/bhv243openalex-snapshot
Dopaminergic Modulation of the Functional Ventrodorsal Architecture of the Human Striatum
inferredcites →https://doi.org/10.1111/ejn.14137openalex-snapshot
Enhanced motivation of cognitive control in Parkinson's disease
inferredcites →https://doi.org/10.1111/j.1471-4159.1990.tb01230.xopenalex-snapshot
Acute Effects of Typical and Atypical Antipsychotic Drugs on the Release of Dopamine from Prefrontal Cortex, Nucleus Accumbens, and Striatum of the Rat: An In Vivo Microdialysis Study
inferredcites →https://doi.org/10.1176/ajp.155.10.1325openalex-snapshot
Dopamine Transporter Occupancies in the Human Brain Induced by Therapeutic Doses of Oral Methylphenidate
inferredcites →https://doi.org/10.1177/0956797618810521openalex-snapshot
Gaze Amplifies Value in Decision Making
inferredcites →https://doi.org/10.1177/1073858408317009openalex-snapshot
Role of Dopamine in the Motivational and Cognitive Control of Behavior
inferredcites →https://doi.org/10.1371/journal.pbio.1001266openalex-snapshot
Neural Mechanisms Underlying Motivation of Mental Versus Physical Effort
inferredcites →https://doi.org/10.1371/journal.pone.0068210openalex-snapshot
What Is the Subjective Cost of Cognitive Effort? Load, Trait, and Aging Effects Revealed by Economic Preference
inferredcites →https://doi.org/10.1523/jneurosci.0454-15.2015openalex-snapshot
Noradrenaline and Dopamine Neurons in the Reward/Effort Trade-Off: A Direct Electrophysiological Comparison in Behaving Monkeys
inferredcites →https://doi.org/10.1523/jneurosci.21-01-00001.2001openalex-snapshot
A Calcium-Dependent Feedback Mechanism Participates in Shaping Single NMDA Miniature EPSCs
inferredcites →https://doi.org/10.1523/jneurosci.21-02-j0001.2001openalex-snapshot
Therapeutic Doses of Oral Methylphenidate Significantly Increase Extracellular Dopamine in the Human Brain
inferredcites →https://doi.org/10.1523/jneurosci.22-14-06272.2002openalex-snapshot
Concurrent Autoreceptor-Mediated Control of Dopamine Release and Uptake during Neurotransmission: AnIn VivoVoltammetric Study
inferredcites →https://doi.org/10.1523/jneurosci.3071-18.2019openalex-snapshot
The Subjective Value of Cognitive Effort is Encoded by a Domain-General Valuation Network
inferredcites →https://doi.org/10.1523/jneurosci.3904-10.2011openalex-snapshot
Dopamine-Mediated Reinforcement Learning Signals in the Striatum and Ventromedial Prefrontal Cortex Underlie Value-Based Choices
inferredcites →https://doi.org/10.3389/fninf.2013.00014openalex-snapshot
HDDM: Hierarchical Bayesian estimation of the Drift-Diffusion Model in Python
inferredcites →https://doi.org/10.3389/fpsyg.2011.00163openalex-snapshot
Striatal Dopamine and the Interface between Motivation and Cognition

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Effects of methylphenidate on reinforcement learning depend on working memory capacity
inferred← citeshttps://doi.org/10.1016/j.neubiorev.2022.104977openalex-snapshot
Emotions as Computations
inferred← citeshttps://doi.org/10.1016/j.neuron.2019.09.035openalex-snapshot
Chemistry of the Adaptive Mind: Lessons from Dopamine
inferred← citeshttps://doi.org/10.1037/dev0001228openalex-snapshot
Effort-related decision-making and its underlying processes during childhood.
inferred← citeshttps://doi.org/10.1037/rev0000442openalex-snapshot
Humans reconfigure target and distractor processing to address distinct task demands.
inferred← citeshttps://doi.org/10.1038/s41380-021-01265-0openalex-snapshot
Influences of dopaminergic system dysfunction on late-life depression
inferred← citeshttps://doi.org/10.1038/s41386-020-0746-4openalex-snapshot
Advances in the computational understanding of mental illness
inferred← citeshttps://doi.org/10.1038/s41386-020-0779-8openalex-snapshot
Dose-response effects of d-amphetamine on effort-based decision-making and reinforcement learning
inferred← citeshttps://doi.org/10.1038/s41386-022-01291-8openalex-snapshot
Cortical dopamine reduces the impact of motivational biases governing automated behaviour
inferred← citeshttps://doi.org/10.1038/s41398-025-03554-6openalex-snapshot
Neurometabolic predictors of mental effort in the frontal cortex
inferred← citeshttps://doi.org/10.1038/s41467-022-32679-1openalex-snapshot
Striatal dopamine dissociates methylphenidate effects on value-based versus surprise-based reversal learning
inferred← citeshttps://doi.org/10.1038/s41467-023-44358-wopenalex-snapshot
Dopamine release in human associative striatum during reversal learning
inferred← citeshttps://doi.org/10.1038/s41467-024-50214-2openalex-snapshot
Gaze-centered gating, reactivation, and reevaluation of economic value in orbitofrontal cortex
inferred← citeshttps://doi.org/10.1038/s41467-024-55644-6openalex-snapshot
Dopaminergic signaling to ventral striatum neurons initiates sniffing behavior
inferred← citeshttps://doi.org/10.1038/s41467-026-70423-1openalex-snapshot
Accumulation of virtual tokens towards a jackpot reward enhances performance and value encoding in dorsal anterior cingulate cortex
inferred← citeshttps://doi.org/10.1038/s41562-022-01306-wopenalex-snapshot
Stress-sensitive inference of task controllability
inferred← citeshttps://doi.org/10.1038/s41562-024-01842-7openalex-snapshot
An experimental manipulation of the value of effort
inferred← citeshttps://doi.org/10.1038/s41572-021-00280-3openalex-snapshot
Parkinson disease-associated cognitive impairment
inferred← citeshttps://doi.org/10.1038/s41598-020-72329-4openalex-snapshot
The cognitive effects of a promised bonus do not depend on dopamine synthesis capacity
inferred← citeshttps://doi.org/10.1038/s41598-022-21917-7openalex-snapshot
Preferences for seeking effort or reward information bias the willingness to work
inferred← citeshttps://doi.org/10.1038/s42003-022-03234-xopenalex-snapshot
Acquisition learning is stronger for aversive than appetitive events
inferred← citeshttps://doi.org/10.1093/med/9780190843014.003.0005openalex-snapshot
Pathophysiology II
inferred← citeshttps://doi.org/10.1097/fbp.0000000000000817openalex-snapshot
‘Only connect’: cognition meets motivation as cognitive effort to enhance models of depression
inferred← citeshttps://doi.org/10.1097/md.0000000000037928openalex-snapshot
Liraglutide-associated depression in a patient with type 2 diabetes: A case report and discussion
inferred← citeshttps://doi.org/10.1101/2020.08.26.264168openalex-snapshot
The cognitive effects of a promised bonus do not depend on dopamine synthesis capacity
inferred← citeshttps://doi.org/10.1113/jp287099openalex-snapshot
Improving brain health via the central executive network
inferred← citeshttps://doi.org/10.1523/eneuro.0360-23.2023openalex-snapshot
Dopamine Increases Accuracy and Lengthens Deliberation Time in Explicit Motor Skill Learning
inferred← citeshttps://doi.org/10.1523/jneurosci.1140-23.2023openalex-snapshot
Dopamine Alters the Effect of Brain Stimulation on Decision-Making
inferred← citeshttps://doi.org/10.31234/osf.io/2sqytopenalex-snapshot
Considering what we know and what we don't know: Expectations and confidence guide value integration in value-based decision-making
inferred← citeshttps://doi.org/10.31234/osf.io/2sqyt_v2openalex-snapshot
Considering what we know and what we don't know: Expectations and confidence guide value integration in value-based decision-making
inferred← citeshttps://doi.org/10.31234/osf.io/57v6kopenalex-snapshot
Fixation patterns in simple choice reflect optimal information sampling
inferred← citeshttps://doi.org/10.31234/osf.io/6rpy5openalex-snapshot
The dorsomedial prefrontal cortex represents subjective value across effort-based and risky decision-making
inferred← citeshttps://doi.org/10.31234/osf.io/726veopenalex-snapshot
The Role of Uncertain Reward in Voluntary Task-switching as Revealed by Pupillometry and Gaze
inferred← citeshttps://doi.org/10.31234/osf.io/gnk4mopenalex-snapshot
An experimental manipulation of the value of effort
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RL or not RL? Parsing the processes that support human reward-based learning.
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On the Rational Boundedness of Cognitive Control: Shared Versus Separated Representations
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Computational mechanisms underlying the dynamics of physical and cognitive fatigue
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“I care about winning some but losing none!”—Attentional mechanism of mutable-hidden zero effect in economic choices
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Classifying Severity of Depression and Anxiety by Analyzing Electroencephalography (EEG) Signals for Neurophysiological Biomarkers
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Neural systems underlying the learning of cognitive effort costs
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Dopaminergic modulation of sensitivity to immediate and delayed punishment during decision-making
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