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Mechanosensitive regulation of FGFR1 through the MRTF-SRF pathway

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/adhm.201601457openalex-snapshot
Hierarchical Micro/Nanofibrous Bioscaffolds for Structural Tissue Regeneration
inferredcites →https://doi.org/10.1002/cm.20052openalex-snapshot
RNAi knockdown of the focal adhesion protein TES reveals its role in actin stress fibre organisation
inferredcites →https://doi.org/10.1002/hep.22193openalex-snapshot
The role of matrix stiffness in regulating cell behavior†
inferredcites →https://doi.org/10.1002/jbm.a.35890openalex-snapshot
Gelatin/chondroitin sulfate nanofibrous scaffolds for stimulation of wound healing: In‐vitro and in‐vivo study
inferredcites →https://doi.org/10.1002/stem.1514openalex-snapshot
FGFR1 Signaling Stimulates Proliferation of Human Mesenchymal Stem Cells by Inhibiting the Cyclin-Dependent Kinase Inhibitors p21Waf1 and p27Kip1
inferredcites →https://doi.org/10.1002/wdev.176openalex-snapshot
The Fibroblast Growth Factor signaling pathway
inferredcites →https://doi.org/10.1002/wnan.100openalex-snapshot
Tissue scaffolds for skin wound healing and dermal reconstruction
inferredcites →https://doi.org/10.1007/s00125-005-1692-8openalex-snapshot
Suppression of Pdx-1 perturbs proinsulin processing, insulin secretion and GLP-1 signalling in INS-1 cells
inferredcites →https://doi.org/10.1007/s00441-009-0834-6openalex-snapshot
Integrins
inferredcites →https://doi.org/10.1007/s11010-007-9654-8openalex-snapshot
Covalently attached FGF-2 to three-dimensional polyamide nanofibrillar surfaces demonstrates enhanced biological stability and activity
inferredcites →https://doi.org/10.1007/s12551-018-0431-6openalex-snapshot
Linker of nucleoskeleton and cytoskeleton complex proteins in cardiomyopathy
inferredcites →https://doi.org/10.1016/j.bbamcr.2004.04.007openalex-snapshot
Focal adhesion regulation of cell behavior
inferredcites →https://doi.org/10.1016/j.biomaterials.2017.06.028openalex-snapshot
Fibrous scaffolds potentiate the paracrine function of mesenchymal stem cells: A new dimension in cell-material interaction
inferredcites →https://doi.org/10.1016/j.biomaterials.2020.119854openalex-snapshot
Dimensionality changes actin network through lamin A/C and zyxin
inferredcites →https://doi.org/10.1016/j.bmcl.2017.02.070openalex-snapshot
Pharmacokinetic optimitzation of CCG-203971: Novel inhibitors of the Rho/MRTF/SRF transcriptional pathway as potential antifibrotic therapeutics for systemic scleroderma
inferredcites →https://doi.org/10.1016/j.canlet.2018.02.015openalex-snapshot
The Hippo/YAP1 pathway interacts with FGFR1 signaling to maintain stemness in lung cancer
inferredcites →https://doi.org/10.1016/j.ceb.2016.01.003openalex-snapshot
Actin flows in cell migration: from locomotion and polarity to trajectories
inferredcites →https://doi.org/10.1016/j.cell.2013.05.008openalex-snapshot
Forces in Tissue Morphogenesis and Patterning
inferredcites →https://doi.org/10.1016/j.cub.2009.06.034openalex-snapshot
The mechanical cell
inferredcites →https://doi.org/10.1016/j.devcel.2010.08.008openalex-snapshot
A Zyxin-Mediated Mechanism for Actin Stress Fiber Maintenance and Repair
inferredcites →https://doi.org/10.1016/j.ijbiomac.2016.07.041openalex-snapshot
Fabrication of FGF-2 immobilized electrospun gelatin nanofibers for tissue engineering
inferredcites →https://doi.org/10.1016/j.mce.2017.09.015openalex-snapshot
Role of fibroblast growth factor receptors (FGFR) and FGFR like-1 (FGFRL1) in mesenchymal stromal cell differentiation to osteoblasts and adipocytes
inferredcites →https://doi.org/10.1016/s1357-2725(99)00123-5openalex-snapshot
Fibroblast growth factor-2
inferredcites →https://doi.org/10.1021/acs.biomac.6b01182openalex-snapshot
A Heparin-Mimicking Block Copolymer Both Stabilizes and Increases the Activity of Fibroblast Growth Factor 2 (FGF2)
inferredcites →https://doi.org/10.1021/acsptsci.8b00048openalex-snapshot
Identification of Pirin as a Molecular Target of the CCG-1423/CCG-203971 Series of Antifibrotic and Antimetastatic Compounds
inferredcites →https://doi.org/10.1038/35048589openalex-snapshot
Attenuation of FGF signalling in mouse β-cells leads to diabetes
inferredcites →https://doi.org/10.1038/nature10137openalex-snapshot
Role of YAP/TAZ in mechanotransduction
inferredcites →https://doi.org/10.1038/nchem.1573openalex-snapshot
A heparin-mimicking polymer conjugate stabilizes basic fibroblast growth factor
inferredcites →https://doi.org/10.1038/ncomms3464openalex-snapshot
Master regulators of FGFR2 signalling and breast cancer risk
inferredcites →https://doi.org/10.1038/nrm2890openalex-snapshot
Linking actin dynamics and gene transcription to drive cellular motile functions
inferredcites →https://doi.org/10.1038/s41388-018-0311-3openalex-snapshot
FGFR1-ERK1/2-SOX2 axis promotes cell proliferation, epithelial–mesenchymal transition, and metastasis in FGFR1-amplified lung cancer
inferredcites →https://doi.org/10.1038/sj.onc.1203121openalex-snapshot
Expression of the SRF gene occurs through a Ras/Sp/SRF-mediated-mechanism in response to serum growth signals
inferredcites →https://doi.org/10.1042/bj20101603openalex-snapshot
Fibroblast growth factors and their receptors in cancer
inferredcites →https://doi.org/10.1046/j.1365-2141.1999.01715.xopenalex-snapshot
Propagation and senescence of human marrow stromal cells in culture: a simple colony‐forming assay identifies samples with the greatest potential to propagate and differentiate
inferredcites →https://doi.org/10.1073/pnas.71.11.4561openalex-snapshot
Antibody to Myosin: The Specific Visualization of Myosin-Containing Filaments in Nonmuscle Cells
inferredcites →https://doi.org/10.1074/jbc.m116.730093openalex-snapshot
Chondrocyte FGFR3 Regulates Bone Mass by Inhibiting Osteogenesis
inferredcites →https://doi.org/10.1074/jbc.m805432200openalex-snapshot
Fibroblast Growth Factor Receptor 2 Promotes Osteogenic Differentiation in Mesenchymal Cells via ERK1/2 and Protein Kinase C Signaling
inferredcites →https://doi.org/10.1089/ten.teb.2014.0123openalex-snapshot
In Vivo Applications of Electrospun Tissue-Engineered Vascular Grafts: A Review
inferredcites →https://doi.org/10.1111/cas.13759openalex-snapshot
Role of fibroblast growth factor receptor 4 in cancer
inferredcites →https://doi.org/10.1111/joa.12243openalex-snapshot
Mechanical regulation of mesenchymal stem cell differentiation
inferredcites →https://doi.org/10.1126/science.276.5317.1425openalex-snapshot
Geometric Control of Cell Life and Death
inferredcites →https://doi.org/10.1128/mcb.02061-05openalex-snapshot
The Rho GTPase Effector ROCK Regulates Cyclin A, Cyclin D1, and p27Kip1 Levels by Distinct Mechanisms
inferredcites →https://doi.org/10.1152/ajpcell.2000.279.5.c1345openalex-snapshot
Substrate flexibility regulates growth and apoptosis of normal but not transformed cells
inferredcites →https://doi.org/10.1152/japplphysiol.01121.2004openalex-snapshot
Cell type-specific response to growth on soft materials
inferredcites →https://doi.org/10.1155/2017/8591073openalex-snapshot
An ECM-Mimicking, Mesenchymal Stem Cell-Embedded Hybrid Scaffold for Bone Regeneration
inferredcites →https://doi.org/10.1158/1078-0432.ccr-14-3212openalex-snapshot
The FGFR Landscape in Cancer: Analysis of 4,853 Tumors by Next-Generation Sequencing
inferredcites →https://doi.org/10.1158/2159-8290.cd-18-0229openalex-snapshot
Efficacy of BGJ398, a Fibroblast Growth Factor Receptor 1–3 Inhibitor, in Patients with Previously Treated Advanced Urothelial Carcinoma with FGFR3 Alterations
inferredcites →https://doi.org/10.1165/rcmb.2006-0034ocopenalex-snapshot
Role of RhoA Inactivation in Reduced Cell Proliferation of Human Airway Smooth Muscle by Simvastatin
inferredcites →https://doi.org/10.1165/rcmb.2008-0099ocopenalex-snapshot
Paxillin Is Involved in the Differential Regulation of Endothelial Barrier by HGF and VEGF
inferredcites →https://doi.org/10.1166/jnn.2011.3753openalex-snapshot
Electrospun Composite Nanofibers for Tissue Regeneration
inferredcites →https://doi.org/10.1186/s13046-019-1236-6openalex-snapshot
FGFs/FGFRs-dependent signalling in regulation of steroid hormone receptors – implications for therapy of luminal breast cancer
inferredcites →https://doi.org/10.1186/s13287-015-0083-4openalex-snapshot
Mechanism of regulation of stem cell differentiation by matrix stiffness
inferredcites →https://doi.org/10.1210/edrv.18.1.0292openalex-snapshot
Biological Roles of Fibroblast Growth Factor-2
inferredcites →https://doi.org/10.1242/jcs.218222openalex-snapshot
SRF'ing and SAP'ing – the role of MRTF proteins in cell migration
inferredcites →https://doi.org/10.1371/journal.pone.0056289openalex-snapshot
Sustained Levels of FGF2 Maintain Undifferentiated Stem Cell Cultures with Biweekly Feeding
inferredcites →https://doi.org/10.1371/journal.pone.0122359openalex-snapshot
Microporous Dermal-Mimetic Electrospun Scaffolds Pre-Seeded with Fibroblasts Promote Tissue Regeneration in Full-Thickness Skin Wounds
inferredcites →https://doi.org/10.1371/journal.pone.0195588openalex-snapshot
Actin and myosin II modulate differentiation of pluripotent stem cells
inferredcites →https://doi.org/10.18632/oncotarget.14109openalex-snapshot
Inhibition of the fibroblast growth factor receptor (FGFR) pathway: the current landscape and barriers to clinical application
inferredcites →https://doi.org/10.2147/ijn.s11883openalex-snapshot
Types of neural guides and using nanotechnology for peripheral nerve reconstruction
inferredcites →https://doi.org/10.2174/13816128113199990594openalex-snapshot
Is Fibroblast Growth Factor Receptor 4 a Suitable Target of Cancer Therapy?
inferredcites →https://doi.org/10.2174/1574888x13666180417120508openalex-snapshot
Electrospun Fibers for Cartilage Tissue Regeneration
inferredcites →https://doi.org/10.2210/pdb6n0k/pdbopenalex-snapshot
The complex of CCG-257081 bound to pirin
inferredcites →https://doi.org/10.3389/fonc.2019.00179openalex-snapshot
Expanding the Arsenal of FGFR Inhibitors: A Novel Chloroacetamide Derivative as a New Irreversible Agent With Anti-proliferative Activity Against FGFR1-Amplified Lung Cancer Cell Lines
inferredcites →https://doi.org/10.3389/fphys.2012.00472openalex-snapshot
Zyxin is involved in regulation of mechanotransduction in arteriole smooth muscle cells
inferredcites →https://doi.org/10.3390/cancers11030406openalex-snapshot
Alpha6-Integrin Regulates FGFR1 Expression through the ZEB1/YAP1 Transcription Complex in Glioblastoma Stem Cells Resulting in Enhanced Proliferation and Stemness
inferredcites →https://doi.org/10.3390/cells7070076openalex-snapshot
Current Status of Fibroblast Growth Factor Receptor-Targeted Therapies in Breast Cancer
inferredcites →https://doi.org/10.3390/cells8010031openalex-snapshot
Fibroblast Growth Factor Receptor 4 Targeting in Cancer: New Insights into Mechanisms and Therapeutic Strategies
inferredcites →https://doi.org/10.3390/ma9080614openalex-snapshot
Electrospun Scaffolds for Corneal Tissue Engineering: A Review
inferredcites →https://doi.org/10.7150/jca.28204openalex-snapshot
Pathological and Prognostic Impacts of FGFR2 Overexpression in Gastric Cancer: A Meta-Analysis

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inferred← citeshttps://doi.org/10.1016/j.biomaterials.2020.120572openalex-snapshot
Steering cell behavior through mechanobiology in 3D: A regenerative medicine perspective
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