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Identification of the Lymphangioleiomyomatosis Cell and Its Uterine Origin

https://doi.org/10.1101/784199
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/gcc.10252openalex-snapshot
Metastasis of benign tumor cells in tuberous sclerosis complex
inferredcites →https://doi.org/10.1002/gcc.10281openalex-snapshot
Uterine leiomyoma in the Eker rat: A unique model for important diseases of women
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Single-Cell Transcriptome Analysis Using SINCERA Pipeline
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Next-generation molecular diagnosis: single-cell sequencing from bench to bedside
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PEComas: the past, the present and the future
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In pulmonary lymphangioleiomyomatosis expression of progesterone receptor is frequently higher than that of estrogen receptor
inferredcites →https://doi.org/10.1016/j.bbagen.2014.01.031openalex-snapshot
Heparan sulfate proteoglycans and heparin regulate melanoma cell functions
inferredcites →https://doi.org/10.1016/j.ccm.2016.04.019openalex-snapshot
Benign Metastasizing Leiomyoma
inferredcites →https://doi.org/10.1016/j.cell.2016.07.054openalex-snapshot
Comprehensive Classification of Retinal Bipolar Neurons by Single-Cell Transcriptomics
inferredcites →https://doi.org/10.1016/j.cell.2019.05.031openalex-snapshot
Comprehensive Integration of Single-Cell Data
inferredcites →https://doi.org/10.1016/j.cels.2015.12.004openalex-snapshot
The Molecular Signatures Database Hallmark Gene Set Collection
inferredcites →https://doi.org/10.1016/j.ejrad.2014.12.008openalex-snapshot
Computed tomographic features of lymphangioleiomyomatosis: Evaluation in 138 patients
inferredcites →https://doi.org/10.1016/j.rmed.2008.11.007openalex-snapshot
Pregnancy experiences among women with lymphangioleiomyomatosis
inferredcites →https://doi.org/10.1016/s0002-9440(10)62958-6openalex-snapshot
Aberrant β-Catenin Signaling in Tuberous Sclerosis
inferredcites →https://doi.org/10.1016/s0002-9440(10)63716-9openalex-snapshot
Role of Discoidin Domain Receptors 1 and 2 in Human Smooth Muscle Cell-Mediated Collagen Remodeling
inferredcites →https://doi.org/10.1016/s0065-230x(05)94005-0openalex-snapshot
Endostatin Signaling and Regulation of Endothelial Cell–Matrix Interactions
inferredcites →https://doi.org/10.1016/s2213-2600(13)70090-0openalex-snapshot
Serum VEGF-D concentration as a biomarker of lymphangioleiomyomatosis severity and treatment response: a prospective analysis of the Multicenter International Lymphangioleiomyomatosis Efficacy of Sirolimus (MILES) trial
inferredcites →https://doi.org/10.1038/modpathol.2008.189openalex-snapshot
Cathepsin-k expression in pulmonary lymphangioleiomyomatosis
inferredcites →https://doi.org/10.1038/nbt.3192openalex-snapshot
Spatial reconstruction of single-cell gene expression data
inferredcites →https://doi.org/10.1038/nbt.4096openalex-snapshot
Integrating single-cell transcriptomic data across different conditions, technologies, and species
inferredcites →https://doi.org/10.1038/ncomms14049openalex-snapshot
Massively parallel digital transcriptional profiling of single cells
inferredcites →https://doi.org/10.1038/s41436-019-0562-6openalex-snapshot
Low-level mosaicism in tuberous sclerosis complex: prevalence, clinical features, and risk of disease transmission
inferredcites →https://doi.org/10.1038/s41592-019-0619-0openalex-snapshot
Fast, sensitive and accurate integration of single-cell data with Harmony
inferredcites →https://doi.org/10.1038/s41598-019-40923-wopenalex-snapshot
Single cell RNA-seq study of wild type and Hox9,10,11 mutant developing uterus
inferredcites →https://doi.org/10.1038/s41598-019-44095-5openalex-snapshot
Essential role of prostaglandin E2 and the EP3 receptor in lymphatic vessel development during zebrafish embryogenesis
inferredcites →https://doi.org/10.1056/nejmoa1100391openalex-snapshot
Efficacy and Safety of Sirolimus in Lymphangioleiomyomatosis
inferredcites →https://doi.org/10.1073/pnas.0400782101openalex-snapshot
A gene atlas of the mouse and human protein-encoding transcriptomes
inferredcites →https://doi.org/10.1073/pnas.1309110110openalex-snapshot
Integration of mTOR and estrogen–ERK2 signaling in lymphangioleiomyomatosis pathogenesis
inferredcites →https://doi.org/10.1073/pnas.1530509100openalex-snapshot
Statistical significance for genomewide studies
inferredcites →https://doi.org/10.1073/pnas.97.11.6085openalex-snapshot
Mutations in the tuberous sclerosis complex gene TSC2 are a cause of sporadic pulmonary lymphangioleiomyomatosis
inferredcites →https://doi.org/10.1080/23723556.2014.998100openalex-snapshot
YAP enters the mTOR pathway to promote tuberous sclerosis complex
inferredcites →https://doi.org/10.1084/jem.20131080openalex-snapshot
Estradiol and mTORC2 cooperate to enhance prostaglandin biosynthesis and tumorigenesis in TSC2-deficient LAM cells
inferredcites →https://doi.org/10.1084/jem.20140341openalex-snapshot
Regulation of YAP by mTOR and autophagy reveals a therapeutic target of Tuberous Sclerosis Complex
inferredcites →https://doi.org/10.1086/301804openalex-snapshot
Evidence That Lymphangiomyomatosis Is Caused by TSC2 Mutations: Chromosome 16p13 Loss of Heterozygosity in Angiomyolipomas and Lymph Nodes from Women with Lymphangiomyomatosis
inferredcites →https://doi.org/10.1089/lrb.2006.4.143openalex-snapshot
Vascular Endothelial Growth Factor-D Is Increased in Serum of Patients with Lymphangioleiomyomatosis
inferredcites →https://doi.org/10.1093/bioinformatics/btl117openalex-snapshot
Pvclust: an R package for assessing the uncertainty in hierarchical clustering
inferredcites →https://doi.org/10.1093/bioinformatics/btt143openalex-snapshot
Shrinkage estimation of dispersion in Negative Binomial models for RNA-seq experiments with small sample size
inferredcites →https://doi.org/10.1093/biostatistics/kxj037openalex-snapshot
Adjusting batch effects in microarray expression data using empirical Bayes methods
inferredcites →https://doi.org/10.1093/database/baw171openalex-snapshot
VerSeDa: vertebrate secretome database
inferredcites →https://doi.org/10.1093/nar/28.1.136openalex-snapshot
BodyMap: a human and mouse gene expression database
inferredcites →https://doi.org/10.1093/nar/gkp427openalex-snapshot
ToppGene Suite for gene list enrichment analysis and candidate gene prioritization
inferredcites →https://doi.org/10.1097/00125480-199901000-00002openalex-snapshot
Melan-A, A New Melanocytic Differentiation Marker
inferredcites →https://doi.org/10.1097/01.pas.0000126859.70814.6dopenalex-snapshot
Lymphangiogenesis in Lymphangioleiomyomatosis
inferredcites →https://doi.org/10.1097/01.pas.0000172192.25295.45openalex-snapshot
Lymphangiogenesis-Mediated Shedding of LAM Cell Clusters as a Mechanism for Dissemination in Lymphangioleiomyomatosis
inferredcites →https://doi.org/10.1097/pas.0b013e318235edbdopenalex-snapshot
Prevalence of Uterine and Adnexal Involvement in Pulmonary Lymphangioleiomyomatosis
inferredcites →https://doi.org/10.1101/267849openalex-snapshot
Cell atlas of human uterus
inferredcites →https://doi.org/10.1101/397588openalex-snapshot
Zero-preserving imputation of scRNA-seq data using low-rank approximation
inferredcites →https://doi.org/10.1101/gr.1239303openalex-snapshot
Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks
inferredcites →https://doi.org/10.1126/science.1260419openalex-snapshot
Tissue-based map of the human proteome
inferredcites →https://doi.org/10.1126/science.aal3321openalex-snapshot
A subcellular map of the human proteome
inferredcites →https://doi.org/10.1146/annurev-med-050715-104245openalex-snapshot
Lymphangioleiomyomatosis: A Monogenic Model of Malignancy
inferredcites →https://doi.org/10.1148/radiol.2421051767openalex-snapshot
Sporadic Lymphangioleiomyomatosis and Tuberous Sclerosis Complex with Lymphangioleiomyomatosis: Comparison of CT Features
inferredcites →https://doi.org/10.1152/ajplung.00311.2003openalex-snapshot
The LAM cell: what is it, where does it come from, and why does it grow?
inferredcites →https://doi.org/10.1158/0008-5472.can-06-1122openalex-snapshot
Identification of the Benign Mesenchymal Tumor Gene HMGA2 in Lymphangiomyomatosis
inferredcites →https://doi.org/10.1158/0008-5472.can-07-6506openalex-snapshot
A Novel Gene Expression Profile in Lymphatics Associated with Tumor Growth and Nodal Metastasis
inferredcites →https://doi.org/10.1158/1541-7786.mcr-17-0077openalex-snapshot
Tuberin Regulates Prostaglandin Receptor–Mediated Viability, via Rheb, in mTORC1-Hyperactive Cells
inferredcites →https://doi.org/10.1159/000331412openalex-snapshot
Derivation of Smooth Muscle Cells with Neural Crest Origin from Human Induced Pluripotent Stem Cells
inferredcites →https://doi.org/10.1164/ajrccm.160.2.9901027openalex-snapshot
Decline in Lung Function in Lymphangioleiomyomatosis: Relation to Menopause and Progesterone Treatment
inferredcites →https://doi.org/10.1164/ajrccm.187.6.663openalex-snapshot
Exonic Mutations of TSC2/TSC1 Are Common but Not Seen in All Sporadic Pulmonary Lymphangioleiomyomatosis
inferredcites →https://doi.org/10.1164/rccm.200911-1737ocopenalex-snapshot
Effects of Prolactin on TSC2 -Null Eker Rat Cells and in Pulmonary Lymphangioleiomyomatosis
inferredcites →https://doi.org/10.1164/rccm.201205-0848oeopenalex-snapshot
Lymphangioleiomyomatosis: Calling It What It Is: A Low-Grade, Destructive, Metastasizing Neoplasm
inferredcites →https://doi.org/10.1164/rccm.201712-2410ocopenalex-snapshot
Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis
inferredcites →https://doi.org/10.1172/jci.insight.87270openalex-snapshot
NK cell activating receptor ligand expression in lymphangioleiomyomatosis is associated with lung function decline
inferredcites →https://doi.org/10.1172/jci.insight.90558openalex-snapshot
Single-cell RNA sequencing identifies diverse roles of epithelial cells in idiopathic pulmonary fibrosis
inferredcites →https://doi.org/10.1172/jci58709openalex-snapshot
Lymphangioleiomyomatosis — a wolf in sheep’s clothing
inferredcites →https://doi.org/10.1183/13993003.00329-2019openalex-snapshot
A genome-wide association study implicatesNR2F2in lymphangioleiomyomatosis pathogenesis
inferredcites →https://doi.org/10.1183/13993003.02066-2018openalex-snapshot
Analysis of the MILES cohort reveals determinants of disease progression and treatment response in lymphangioleiomyomatosis
inferredcites →https://doi.org/10.1186/s40169-017-0145-6openalex-snapshot
Single‐cell sequencing and tumorigenesis: improved understanding of tumor evolution and metastasis
inferredcites →https://doi.org/10.1196/annals.1413.018openalex-snapshot
Lymphatic Involvement in Lymphangioleiomyomatosis
inferredcites →https://doi.org/10.1210/en.2016-1395openalex-snapshot
Minireview: Lymphangioleiomyomatosis (LAM): The “Other” Steroid-Sensitive Cancer
inferredcites →https://doi.org/10.1210/me.2013-1059openalex-snapshot
Uterine-Specific Loss of Tsc2 Leads to Myometrial Tumors in Both the Uterus and Lungs
inferredcites →https://doi.org/10.1369/0022155413489311openalex-snapshot
Lymphatic Endothelial Differentiation in Pulmonary Lymphangioleiomyomatosis Cells
inferredcites →https://doi.org/10.1369/jhc.4a6438.2004openalex-snapshot
Combined Smooth Muscle and Melanocytic Differentiation in Lymphangioleiomyomatosis
inferredcites →https://doi.org/10.1371/journal.pcbi.1004575openalex-snapshot
SINCERA: A Pipeline for Single-Cell RNA-Seq Profiling Analysis
inferredcites →https://doi.org/10.1371/journal.pone.0015004openalex-snapshot
Aptamer-Based Multiplexed Proteomic Technology for Biomarker Discovery
inferredcites →https://doi.org/10.1371/journal.pone.0126025openalex-snapshot
Wild Type Mesenchymal Cells Contribute to the Lung Pathology of Lymphangioleiomyomatosis
inferredcites →https://doi.org/10.1371/journal.pone.0146653openalex-snapshot
Role of Prolactin Receptors in Lymphangioleiomyomatosis
inferredcites →https://doi.org/10.1378/chest.91.5.782openalex-snapshot
Exacerbation of Pulmonary Lymphangioleiomyomatosis by Exogenous Estrogens
inferredcites →https://doi.org/10.1513/annalsats.201703-229leopenalex-snapshot
Apparent Sporadic Lymphangioleiomyomatosis in a Man as a Result of Extreme Mosaicism for a TSC2 Mutation
inferredcites →https://doi.org/10.1530/erc-15-0505openalex-snapshot
Estrogen maintains myometrial tumors in a lymphangioleiomyomatosis model
inferredcites →https://doi.org/10.2310/6650.2001.33787openalex-snapshot
Distribution and mRNA Expression of Insulin-Like Growth Factor System in Pulmonary Lymphangioleiomyomatosis
inferredcites →https://doi.org/10.3389/fcell.2014.00069openalex-snapshot
The neural crest lineage as a driver of disease heterogeneity in Tuberous Sclerosis Complex and Lymphangioleiomyomatosis
inferredcites →https://doi.org/10.5858/2000-124-0267-rfaommopenalex-snapshot
Role for Activation of Matrix Metalloproteinases in the Pathogenesis of Pulmonary Lymphangioleiomyomatosis

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1007/978-3-031-12950-6_20openalex-snapshot
Diffuse Cystic Lung Disease
inferred← citeshttps://doi.org/10.1016/j.path.2019.11.007openalex-snapshot
Pulmonary Cystic Disease and Its Mimics
inferred← citeshttps://doi.org/10.1101/2020.06.19.161851openalex-snapshot
Lung at a Glance: an integrative web toolset of lung ontology, imaging and single cell omics
inferred← citeshttps://doi.org/10.1101/683359openalex-snapshot
Genome-wide functional genomics screens identify therapeutic vulnerabilities for lymphangioleiomyomatosis
inferred← citeshttps://doi.org/10.1183/20734735.0007-2020openalex-snapshot
Lymphangioleiomyomatosis: a clinical review
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