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Further Exploration of the SAR of Imidazoquinolines; Identification of Potent C7 Substituted Imidazoquinolines

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Mild and General Methods for the Palladium‐Catalyzed Cyanation of Aryl and Heteroaryl Chlorides.
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A New Approach to Vaccine Adjuvants
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Pathogen recognition by innate receptors
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Regioisomerism-dependent TLR7 agonism and antagonism in an imidazoquinoline
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Novel perspectives on dendritic cell-based immunotherapy of cancer
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Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA
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Review Article Imiquimod applied topically: a novel immune response modifier and new class of drug
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Success of HPV vaccination is now a matter of coverage
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Design and Synthesis of N1-Modified Imidazoquinoline Agonists for Selective Activation of Toll-like Receptors 7 and 8
inferredcites →https://doi.org/10.1021/jm049211vopenalex-snapshot
Synthesis and Structure−Activity-Relationships of 1H-Imidazo[4,5-c]quinolines That Induce Interferon Production
inferredcites →https://doi.org/10.1021/jm100358copenalex-snapshot
Structure−Activity Relationships in Human Toll-Like Receptor 7-Active Imidazoquinoline Analogues
inferredcites →https://doi.org/10.1021/jm4004957openalex-snapshot
Structure–Activity Relationship Analysis of Imidazoquinolines with Toll-like Receptors 7 and 8 Selectivity and Enhanced Cytokine Induction
inferredcites →https://doi.org/10.1021/ml300079eopenalex-snapshot
Discovery of Imidazoquinolines with Toll-Like Receptor 7/8 Independent Cytokine Induction
inferredcites →https://doi.org/10.1021/ol070372dopenalex-snapshot
Mild and General Methods for the Palladium-Catalyzed Cyanation of Aryl and Heteroaryl Chlorides
inferredcites →https://doi.org/10.1038/90609openalex-snapshot
Toll-like receptors: critical proteins linking innate and acquired immunity
inferredcites →https://doi.org/10.1038/ni.1863openalex-snapshot
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
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In vivothickness measurement of basal cell carcinoma and actinic keratosis with optical coherence tomography and 20-MHz ultrasound
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Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8
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Regulation of Adaptive Immunity by the Innate Immune System
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Structural Reorganization of the Toll-Like Receptor 8 Dimer Induced by Agonistic Ligands
inferredcites →https://doi.org/10.1182/blood-2015-02-630335openalex-snapshot
Topical resiquimod can induce disease regression and enhance T-cell effector functions in cutaneous T-cell lymphoma
inferredcites →https://doi.org/10.4049/jimmunol.168.9.4531openalex-snapshot
Quantitative Expression of Toll-Like Receptor 1–10 mRNA in Cellular Subsets of Human Peripheral Blood Mononuclear Cells and Sensitivity to CpG Oligodeoxynucleotides
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