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Multispectral Imaging Differentiates Unique Macrophage Profiles in Patients with Distinct Chronic Liver Diseases

https://doi.org/10.1101/794610
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Outgoing claims: the papers this work cites, builds on, or argues with.

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Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis†
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The Liver as an Immunological Organ
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Monocyte subsets in human liver disease show distinct phenotypic and functional characteristics
inferredcites →https://doi.org/10.1002/hep.27254openalex-snapshot
Immune tolerance in liver disease
inferredcites →https://doi.org/10.1002/hep.29477openalex-snapshot
A randomized, placebo‐controlled trial of cenicriviroc for treatment of nonalcoholic steatohepatitis with fibrosis
inferredcites →https://doi.org/10.1002/hep.29544openalex-snapshot
Therapeutic inhibition of inflammatory monocyte recruitment reduces steatohepatitis and liver fibrosis
inferredcites →https://doi.org/10.1002/hep4.1356openalex-snapshot
Liver Macrophages: Old Dogmas and New Insights
inferredcites →https://doi.org/10.1002/path.5026openalex-snapshot
Multispectral imaging for quantitative and compartment‐specific immune infiltrates reveals distinct immune profiles that classify lung cancer patients
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Tyramide Signal Amplification for Immunofluorescent Enhancement
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Multiobjective evolutionary algorithms to identify highly autocorrelated areas: the case of spatial distribution in financially compromised farms
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Histological grading and staging of chronic hepatitis
inferredcites →https://doi.org/10.1016/j.ajpath.2011.01.023openalex-snapshot
Recently Infiltrating MAC387+ Monocytes/Macrophages
inferredcites →https://doi.org/10.1016/j.humpath.2012.05.009openalex-snapshot
A colorful future of quantitative pathology: validation of Vectra technology using chromogenic multiplexed immunohistochemistry and prostate tissue microarrays
inferredcites →https://doi.org/10.1016/j.jcmgh.2015.12.005openalex-snapshot
Hepatitis C Virus-Induced Monocyte Differentiation Into Polarized M2 Macrophages Promotes Stellate Cell Activation via TGF-β
inferredcites →https://doi.org/10.1016/j.jhep.2014.02.031openalex-snapshot
Image analysis of liver biopsy samples measures fibrosis and predicts clinical outcome
inferredcites →https://doi.org/10.1016/j.jhep.2017.02.026openalex-snapshot
Targeting hepatic macrophages to treat liver diseases
inferredcites →https://doi.org/10.1016/j.jim.2015.08.001openalex-snapshot
Impact of Detachment Methods on M2 Macrophage Phenotype and Function
inferredcites →https://doi.org/10.1016/j.molimm.2017.02.018openalex-snapshot
The role of Kupffer cells in hepatic diseases
inferredcites →https://doi.org/10.1016/j.ymeth.2014.08.016openalex-snapshot
Multiplexed immunohistochemistry, imaging, and quantitation: A review, with an assessment of Tyramide signal amplification, multispectral imaging and multiplex analysis
inferredcites →https://doi.org/10.1016/s0171-2985(81)80090-3openalex-snapshot
Influence of Various Detachment Procedures on the Functional State of Cultured Murine Macrophages
inferredcites →https://doi.org/10.1038/cmi.2015.104openalex-snapshot
Hepatic macrophages in homeostasis and liver diseases: from pathogenesis to novel therapeutic strategies
inferredcites →https://doi.org/10.1038/nrgastro.2015.200openalex-snapshot
Immunology in the liver — from homeostasis to disease
inferredcites →https://doi.org/10.1038/nri.2017.11openalex-snapshot
Liver macrophages in tissue homeostasis and disease
inferredcites →https://doi.org/10.1038/s41467-018-06318-7openalex-snapshot
Single cell RNA sequencing of human liver reveals distinct intrahepatic macrophage populations
inferredcites →https://doi.org/10.1038/s41598-018-37071-yopenalex-snapshot
Fibrogenic Gene Expression in Hepatic Stellate Cells Induced by HCV and HIV Replication in a Three Cell Co-Culture Model System
inferredcites →https://doi.org/10.1038/srep36160openalex-snapshot
HCV core protein inhibits polarization and activity of both M1 and M2 macrophages through the TLR2 signaling pathway
inferredcites →https://doi.org/10.1038/srep39520openalex-snapshot
Chronic hepatitis C infection–induced liver fibrogenesis is associated with M2 macrophage activation
inferredcites →https://doi.org/10.1038/srep44356openalex-snapshot
Immunofluorescence identifies distinct subsets of endothelial cells in the human liver
inferredcites →https://doi.org/10.1053/j.gastro.2009.09.009openalex-snapshot
Hepatitis C Virus Core Protein Subverts the Antiviral Activities of Human Kupffer Cells
inferredcites →https://doi.org/10.1053/j.gastro.2011.06.063openalex-snapshot
Host Response to Translocated Microbial Products Predicts Outcomes of Patients With HBV or HCV Infection
inferredcites →https://doi.org/10.1056/nejmoa1604958openalex-snapshot
Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma
inferredcites →https://doi.org/10.1111/ajt.13749openalex-snapshot
Functional Immune Anatomy of the Liver—As an Allograft
inferredcites →https://doi.org/10.1111/liv.12050openalex-snapshot
Portal, but not lobular, macrophages express matrix metalloproteinase‐9: association with the ductular reaction and fibrosis in chronic hepatitis C
inferredcites →https://doi.org/10.1126/scitranslmed.aad6352openalex-snapshot
The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis
inferredcites →https://doi.org/10.1136/gut.46.2.260openalex-snapshot
Increases in intrahepatic CD68 positive cells, MAC387 positive cells, and proinflammatory cytokines (particularly interleukin 18) in chronic hepatitis C infection
inferredcites →https://doi.org/10.1158/2326-6066.cir-14-0244openalex-snapshot
Resistance to Antiangiogenic Therapy Is Associated with an Immunosuppressive Tumor Microenvironment in Metastatic Renal Cell Carcinoma
inferredcites →https://doi.org/10.1186/s40169-015-0047-4openalex-snapshot
The significance of macrophage polarization subtypes for animal models of tissue fibrosis and human fibrotic diseases
inferredcites →https://doi.org/10.1186/s40425-016-0115-3openalex-snapshot
Multiplexed tissue biomarker imaging
inferredcites →https://doi.org/10.1189/jlb.0604332openalex-snapshot
Development and functional consequences of LPS tolerance in sinusoidal endothelial cells of the liver
inferredcites →https://doi.org/10.1371/journal.pone.0011049openalex-snapshot
Functional Contribution of Elevated Circulating and Hepatic Non-Classical CD14+CD16+ Monocytes to Inflammation and Human Liver Fibrosis
inferredcites →https://doi.org/10.1371/journal.pone.0019968openalex-snapshot
Differential Expression of CD163 on Monocyte Subsets in Healthy and HIV-1 Infected Individuals
inferredcites →https://doi.org/10.1371/journal.pone.0159524openalex-snapshot
Kupffer Cells Undergo Fundamental Changes during the Development of Experimental NASH and Are Critical in Initiating Liver Damage and Inflammation
inferredcites →https://doi.org/10.18632/oncotarget.12275openalex-snapshot
Immune cells in liver regeneration
inferredcites →https://doi.org/10.3389/fimmu.2019.00893openalex-snapshot
The Role of Myeloid-Derived Cells in the Progression of Liver Disease
inferredcites →https://doi.org/10.3760/cma.j.issn.0578-1426.2017.10.011openalex-snapshot
[The study of liver macrophages polarization in patients with autoimmune hepatitis].
inferredcites →https://doi.org/10.3892/mmr.2016.4998openalex-snapshot
Altered function of monocytes/macrophages in patients with autoimmune hepatitis
inferredcites →https://doi.org/10.4049/jimmunol.1701262openalex-snapshot
Eight-Color Multiplex Immunohistochemistry for Simultaneous Detection of Multiple Immune Checkpoint Molecules within the Tumor Microenvironment
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