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Overlap in synaptic neurological condition susceptibility pathways and the neural pannexin 1 interactome revealed by bioinformatics analyses
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Connexins and pannexins in Alzheimer’s disease
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A genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations
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ERK (MAPK) does not phosphorylate tau under physiological conditions in vivo or in vitro
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α-Actinin Anchors PSD-95 at Postsynaptic Sites
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Pannexin-1 channel dysfunction in the medial prefrontal cortex mediates depressive-like behaviors induced by chronic social defeat stress and administration of mefloquine in mice
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Protein-protein interactions at the NMDA receptor complex: From synaptic retention to synaptonuclear protein messengers
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CRMP2–Neurofibromin Interface Drives NF1-related Pain
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Purinergic signaling in nervous system health and disease: Focus on pannexin 1
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14-3-3 adaptor protein-protein interactions as therapeutic targets for CNS diseases
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How Schizophrenia Develops: Cognitive and Brain Mechanisms Underlying Onset of Psychosis
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Non-junction functions of pannexin-1 channels
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De novo GRIN2A variants associated with epilepsy and autism and literature review
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Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis
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Up-regulation of mitogen-activated protein kinases ERK1/2 and MEK1/2 is associated with the progression of neurofibrillary degeneration in Alzheimer’s disease
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The AMPA Receptor GluR2 C Terminus Can Mediate a Reversible, ATP-Dependent Interaction with NSF and α- and β-SNAPs
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Genetic insights in Alzheimer's disease
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Heat shock proteins as potential targets for protective strategies in neurodegeneration
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Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study
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Five novel loci associated with antipsychotic treatment response in patients with schizophrenia: a genome-wide association study
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Global, regional, and national burden of 12 mental disorders in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
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Accurate and Sensitive Peptide Identification with Mascot Percolator
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Gene Ontology: tool for the unification of biology
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Proteomic analysis of NMDA receptor–adhesion protein signaling complexes
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Ionotropic receptors and ion channels in ischemic neuronal death and dysfunction
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Metaplasticity gated through differential regulation of GluN2A versus GluN2B receptors by Src family kinases
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Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease
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Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder
inferredcites →https://doi.org/10.1038/mp.2013.138openalex-snapshot
Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia
inferredcites →https://doi.org/10.1038/mp.2015.218openalex-snapshot
Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer’s disease with OSBPL6, PTPRG, and PDCL3
inferredcites →https://doi.org/10.1038/mp.2015.23openalex-snapshot
A novel Alzheimer disease locus located near the gene encoding tau protein
inferredcites →https://doi.org/10.1038/mp.2016.198openalex-snapshot
ASD and schizophrenia show distinct developmental profiles in common genetic overlap with population-based social communication difficulties
inferredcites →https://doi.org/10.1038/nature08185openalex-snapshot
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
inferredcites →https://doi.org/10.1038/nature11860openalex-snapshot
Activity-dependent neuronal signalling and autism spectrum disorder
inferredcites →https://doi.org/10.1038/nature13595openalex-snapshot
Biological insights from 108 schizophrenia-associated genetic loci
inferredcites →https://doi.org/10.1038/nbt1210-1248openalex-snapshot
Towards a knowledge-based Human Protein Atlas
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Brain-specific Crmp2 deletion leads to neuronal development deficits and behavioural impairments in mice
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Genome-wide association study implicates NDST3 in schizophrenia and bipolar disorder
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Genome-wide association analysis identifies 13 new risk loci for schizophrenia
inferredcites →https://doi.org/10.1038/ng.3955openalex-snapshot
A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci
inferredcites →https://doi.org/10.1038/ng.3973openalex-snapshot
Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia
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Genome-wide association study reveals genetic risk underlying Parkinson's disease
inferredcites →https://doi.org/10.1038/ng.642openalex-snapshot
Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease
inferredcites →https://doi.org/10.1038/ng.940openalex-snapshot
Genome-wide association study identifies five new schizophrenia loci
inferredcites →https://doi.org/10.1038/ng.980openalex-snapshot
Common variants on 8p12 and 1q24.2 confer risk of schizophrenia
inferredcites →https://doi.org/10.1038/nm1088openalex-snapshot
Reticulon family members modulate BACE1 activity and amyloid-β peptide generation
inferredcites →https://doi.org/10.1038/nn.2741openalex-snapshot
Dendritic spine pathology in neuropsychiatric disorders
inferredcites →https://doi.org/10.1038/nn.4236openalex-snapshot
Metabotropic NMDA receptor signaling couples Src family kinases to pannexin-1 during excitotoxicity
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GWAS on family history of Alzheimer’s disease
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Haploinsufficiency of the schizophrenia and autism risk gene Cyfip1 causes abnormal postnatal hippocampal neurogenesis through microglial and Arp2/3 mediated actin dependent mechanisms
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Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies
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Serine synthesis through PHGDH coordinates nucleotide levels by maintaining central carbon metabolism
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Abnormalities of signal transduction networks in chronic schizophrenia
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Benefits and limitations of genome-wide association studies
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Mitochondria as central regulators of neural stem cell fate and cognitive function
inferredcites →https://doi.org/10.1038/s41586-022-04556-wopenalex-snapshot
Rare coding variants in ten genes confer substantial risk for schizophrenia
inferredcites →https://doi.org/10.1038/s41588-018-0059-2openalex-snapshot
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
inferredcites →https://doi.org/10.1038/s41588-019-0344-8openalex-snapshot
Identification of common genetic risk variants for autism spectrum disorder
inferredcites →https://doi.org/10.1038/s41588-019-0358-2openalex-snapshot
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
inferredcites →https://doi.org/10.1038/s41596-019-0128-8openalex-snapshot
Protocol Update for large-scale genome and gene function analysis with the PANTHER classification system (v.14.0)
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Enriching Traditional Protein-protein Interaction Networks with Alternative Conformations of Proteins
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Identification of ultra-rare genetic variants in pediatric acute onset neuropsychiatric syndrome (PANS) by exome and whole genome sequencing
inferredcites →https://doi.org/10.1038/sj.emboj.7601707openalex-snapshot
Transgenic mice overexpressing reticulon 3 develop neuritic abnormalities
inferredcites →https://doi.org/10.1038/tp.2013.50openalex-snapshot
Autism-specific maternal autoantibodies recognize critical proteins in developing brain
inferredcites →https://doi.org/10.1042/bsr20150295openalex-snapshot
Combined defects in oxidative phosphorylation and fatty acid β-oxidation in mitochondrial disease
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Rabs and their effectors: Achieving specificity in membrane traffic
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Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia
inferredcites →https://doi.org/10.1073/pnas.1417989112openalex-snapshot
Giant ankyrin-G stabilizes somatodendritic GABAergic synapses through opposing endocytosis of GABA A receptors
inferredcites →https://doi.org/10.1073/pnas.1618417114openalex-snapshot
Protein homeostasis of a metastable subproteome associated with Alzheimer’s disease
inferredcites →https://doi.org/10.1073/pnas.84.23.8210openalex-snapshot
Four additional members of the ras gene superfamily isolated by an oligonucleotide strategy: molecular cloning of YPT-related cDNAs from a rat brain library.
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Collapsin Response Mediator Protein 2 (CRMP2) Interacts with N-Methyl-d-aspartate (NMDA) Receptor and Na+/Ca2+ Exchanger and Regulates Their Functional Activity
inferredcites →https://doi.org/10.1074/jbc.m116.717934openalex-snapshot
A Germline Variant in the PANX1 Gene Has Reduced Channel Function and Is Associated with Multisystem Dysfunction
inferredcites →https://doi.org/10.1074/mcp.m111.011056openalex-snapshot
Estrogen Receptor Alpha Interacts with Mitochondrial Protein HADHB and Affects Beta-Oxidation Activity
inferredcites →https://doi.org/10.1074/mcp.m113.037291openalex-snapshot
Deep Proteomic Evaluation of Primary and Cell Line Motoneuron Disease Models Delineates Major Differences in Neuronal Characteristics
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Rab GTPases and their interacting protein partners: Structural insights into Rab functional diversity
inferredcites →https://doi.org/10.1083/jcb.201206028openalex-snapshot
Interaction between autism-linked MDGAs and neuroligins suppresses inhibitory synapse development
inferredcites →https://doi.org/10.1085/jgp.201711888openalex-snapshot
Revisiting multimodal activation and channel properties of Pannexin 1
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BioMart and Bioconductor: a powerful link between biological databases and microarray data analysis
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bioDBnet: the biological database network
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Modeling sample variables with an Experimental Factor Ontology
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gwasrapidd: an R package to query, download and wrangle GWAS catalog data
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Mutation burden analysis of six common mental disorders in African Americans by whole genome sequencing
inferredcites →https://doi.org/10.1093/hmg/ddr550openalex-snapshot
Two-stage genome-wide association study identifies variants in CAMSAP1L1 as susceptibility loci for epilepsy in Chinese
inferredcites →https://doi.org/10.1093/hmg/ddy129openalex-snapshot
Differential effects of 14-3-3 dimers on Tau phosphorylation, stability and toxicity in vivo
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KEGG: Kyoto Encyclopedia of Genes and Genomes
inferredcites →https://doi.org/10.1093/nar/30.7.1575openalex-snapshot
An efficient algorithm for large-scale detection of protein families
inferredcites →https://doi.org/10.1093/nar/gkaa1074openalex-snapshot
The STRING database in 2021: customizable protein–protein networks, and functional characterization of user-uploaded gene/measurement sets
inferredcites →https://doi.org/10.1093/nar/gkaa1083openalex-snapshot
Mouse Genome Database (MGD): Knowledgebase for mouse–human comparative biology
inferredcites →https://doi.org/10.1093/nar/gkaa1106openalex-snapshot
PANTHER version 16: a revised family classification, tree-based classification tool, enhancer regions and extensive API
inferredcites →https://doi.org/10.1093/nar/gkaa1113openalex-snapshot
The Gene Ontology resource: enriching a GOld mine
inferredcites →https://doi.org/10.1093/nar/gkac1000openalex-snapshot
The STRING database in 2023: protein–protein association networks and functional enrichment analyses for any sequenced genome of interest
inferredcites →https://doi.org/10.1093/nar/gkac1010openalex-snapshot
The NHGRI-EBI GWAS Catalog: knowledgebase and deposition resource
inferredcites →https://doi.org/10.1093/nar/gkac888openalex-snapshot
Genenames.org: the HGNC resources in 2023
inferredcites →https://doi.org/10.1093/nar/gki418openalex-snapshot
FFAS03: a server for profile-profile sequence alignments
inferredcites →https://doi.org/10.1093/nar/gks1118openalex-snapshot
PANTHER in 2013: modeling the evolution of gene function, and other gene attributes, in the context of phylogenetic trees
inferredcites →https://doi.org/10.1093/nar/gkv007openalex-snapshot
limma powers differential expression analyses for RNA-sequencing and microarray studies
inferredcites →https://doi.org/10.1093/nar/gkv1351openalex-snapshot
The Reactome pathway Knowledgebase
inferredcites →https://doi.org/10.1093/nar/gkw1092openalex-snapshot
KEGG: new perspectives on genomes, pathways, diseases and drugs
inferredcites →https://doi.org/10.1093/nar/gkw937openalex-snapshot
The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible
inferredcites →https://doi.org/10.1093/nar/gky1038openalex-snapshot
PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools
inferredcites →https://doi.org/10.1093/nar/gky1120openalex-snapshot
The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019
inferredcites →https://doi.org/10.1093/nar/gky1131openalex-snapshot
STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
inferredcites →https://doi.org/10.1093/nar/gky962openalex-snapshot
New approach for understanding genome variations in KEGG
inferredcites →https://doi.org/10.1093/schbul/sbn155openalex-snapshot
A Genome-Wide Association Study of Schizophrenia Using Brain Activation as a Quantitative Phenotype
inferredcites →https://doi.org/10.1093/schbul/sby140openalex-snapshot
Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect
inferredcites →https://doi.org/10.1097/fpc.0000000000000250openalex-snapshot
Genome-wide association study of paliperidone efficacy
inferredcites →https://doi.org/10.1097/yic.0000000000000198openalex-snapshot
A molecular pathway analysis informs the genetic risk for arrhythmias during antipsychotic treatment
inferredcites →https://doi.org/10.1098/rstb.2014.0191openalex-snapshot
ATP release through pannexon channels
inferredcites →https://doi.org/10.1101/2020.03.02.973917openalex-snapshot
Pannexin 1 regulates spiny protrusion dynamics in cortical neurons
inferredcites →https://doi.org/10.1101/496141openalex-snapshot
Modulation of ERK1/MAPK3 potentiates ERK nuclear signalling, facilitates neuronal cell survival and improves memory in mouse models of neurodegenerative disorders
inferredcites →https://doi.org/10.1101/gr.772403openalex-snapshot
PANTHER: A Library of Protein Families and Subfamilies Indexed by Function
inferredcites →https://doi.org/10.1109/jproc.2008.925458openalex-snapshot
CellDesigner 3.5: A Versatile Modeling Tool for Biochemical Networks
inferredcites →https://doi.org/10.1111/j.1365-2990.2007.00846.xopenalex-snapshot
Rab6 is increased in Alzheimer's disease brain and correlates with endoplasmic reticulum stress
inferredcites →https://doi.org/10.1111/j.1460-9568.2005.04139.xopenalex-snapshot
Site‐specific and developmental expression of pannexin1 in the mouse nervous system
inferredcites →https://doi.org/10.1111/j.1460-9568.2006.05005.xopenalex-snapshot
Reticulons RTN3 and RTN4‐B/C interact with BACE1 and inhibit its ability to produce amyloid β‐protein
inferredcites →https://doi.org/10.1111/j.1460-9568.2011.07628.xopenalex-snapshot
Molecular basis of NMDA receptor functional diversity
inferredcites →https://doi.org/10.1111/j.1469-1809.2012.00721.xopenalex-snapshot
Genome‐Wide Association and Linkage Study in the Amish Detects a Novel Candidate Late‐Onset Alzheimer Disease Gene
inferredcites →https://doi.org/10.1111/j.1471-4159.2007.04829.xopenalex-snapshot
Collapsin response mediator protein‐2 hyperphosphorylation is an early event in Alzheimer’s disease progression
inferredcites →https://doi.org/10.1111/j.1471-4159.2011.07210.xopenalex-snapshot
ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels
inferredcites →https://doi.org/10.1111/jnc.15004openalex-snapshot
Pannexin‐1 in the CNS: Emerging concepts in health and disease
inferredcites →https://doi.org/10.1111/pcn.12899openalex-snapshot
Plasticity of dendritic spines: Molecular function and dysfunction in neurodevelopmental disorders
inferredcites →https://doi.org/10.1124/pr.114.010397openalex-snapshot
Regulation of the Dopamine and Vesicular Monoamine Transporters: Pharmacological Targets and Implications for Disease
inferredcites →https://doi.org/10.1126/science.aap8757openalex-snapshot
Analysis of shared heritability in common disorders of the brain
inferredcites →https://doi.org/10.1126/science.aay5947openalex-snapshot
An atlas of the protein-coding genes in the human, pig, and mouse brain
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What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1007/s10561-020-09896-3openalex-snapshot
Stem cell-based therapy as a promising approach in Alzheimer's disease: current perspectives on novel treatment
inferred← citeshttps://doi.org/10.1016/j.ceca.2020.102253openalex-snapshot
PANX1 in inflammation heats up: New mechanistic insights with implications for injury and infection
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2021.107840openalex-snapshot
Purinergic signaling in nervous system health and disease: Focus on pannexin 1
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