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Comprehensive molecular characterization of pediatric treatment-induced high-grade glioma: A distinct entity despite disparate etiologies with defining molecular characteristics and potential therapeutic targets

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/(sici)1098-2264(199907)25:3<261::aid-gcc8>3.0.co;2-#openalex-snapshot

1q23 gain is associated with progressive neuroblastoma resistant to aggressive treatment

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Sarcoma in irradiated bone. Report of eleven cases

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High‐grade gliomas in patients with prior systemic malignancies

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RET/PTC and PAX8/PPARγ chromosomal rearrangements in post‐Chernobyl thyroid cancer and their association with iodine‐131 radiation dose and other characteristics

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ETV6‐NTRK3 is a common chromosomal rearrangement in radiation‐associated thyroid cancer

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Crosstalk Between the PI3K/mTOR and MEK/ERK Pathways Involved in the Maintenance of Self-Renewal and Tumorigenicity of Glioblastoma Stem-Like Cells

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H3-/IDH-wild type pediatric glioblastoma is comprised of molecularly and prognostically distinct subtypes with associated oncogenic drivers

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The genetic landscape of gliomas arising after therapeutic radiation

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Structure and evolution of double minutes in diagnosis and relapse brain tumors

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Multiobjective evolutionary algorithms to identify highly autocorrelated areas: the case of spatial distribution in financially compromised farms

inferredcites →https://doi.org/10.1016/j.ccell.2017.08.017openalex-snapshot

Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma

inferredcites →https://doi.org/10.1016/j.ccell.2018.04.004openalex-snapshot

Molecular, Pathological, Radiological, and Immune Profiling of Non-brainstem Pediatric High-Grade Glioma from the HERBY Phase II Randomized Trial

inferredcites →https://doi.org/10.1016/j.cell.2013.02.023openalex-snapshot

Criteria for Inference of Chromothripsis in Cancer Genomes

inferredcites →https://doi.org/10.1016/j.chom.2015.11.002openalex-snapshot

Meta- and Orthogonal Integration of Influenza “OMICs” Data Defines a Role for UBR4 in Virus Budding

inferredcites →https://doi.org/10.1016/j.neuroimage.2010.07.033openalex-snapshot

Unbiased average age-appropriate atlases for pediatric studies

inferredcites →https://doi.org/10.1016/j.neuroimage.2010.09.025openalex-snapshot

A reproducible evaluation of ANTs similarity metric performance in brain image registration

inferredcites →https://doi.org/10.1016/j.radonc.2006.08.005openalex-snapshot

Outcome of secondary high-grade glioma in children previously treated for a malignant condition: A study of the Canadian Pediatric Brain Tumour Consortium

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Gain of 1q Is Associated with Adverse Outcome in Favorable Histology Wilms’ Tumors

inferredcites →https://doi.org/10.1038/75556openalex-snapshot

Gene Ontology: tool for the unification of biology

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The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

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A novel retinoblastoma therapy from genomic and epigenetic analyses

inferredcites →https://doi.org/10.1038/nature10910openalex-snapshot

Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes

inferredcites →https://doi.org/10.1038/nature13109openalex-snapshot

C11orf95–RELA fusions drive oncogenic NF-κB signalling in ependymoma

inferredcites →https://doi.org/10.1038/nature15393openalex-snapshot

A global reference for human genetic variation

inferredcites →https://doi.org/10.1038/nature19057openalex-snapshot

Analysis of protein-coding genetic variation in 60,706 humans

inferredcites →https://doi.org/10.1038/nature21356openalex-snapshot

Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity

inferredcites →https://doi.org/10.1038/nature26000openalex-snapshot

DNA methylation-based classification of central nervous system tumours

inferredcites →https://doi.org/10.1038/ncomms12605openalex-snapshot

Mutational signatures of ionizing radiation in second malignancies

inferredcites →https://doi.org/10.1038/ncomms9891openalex-snapshot

Recurrent internal tandem duplications of BCOR in clear cell sarcoma of the kidney

inferredcites →https://doi.org/10.1038/ng.2287openalex-snapshot

The Pediatric Cancer Genome Project

inferredcites →https://doi.org/10.1038/ng.2938openalex-snapshot

The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma

inferredcites →https://doi.org/10.1038/ng1180openalex-snapshot

PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

inferredcites →https://doi.org/10.1038/nmeth.1628openalex-snapshot

CREST maps somatic structural variation in cancer genomes with base-pair resolution

inferredcites →https://doi.org/10.1038/nmeth.3394openalex-snapshot

CONSERTING: integrating copy-number analysis with structural-variation detection

inferredcites →https://doi.org/10.1038/nn1050openalex-snapshot

Voxel-based lesion–symptom mapping

inferredcites →https://doi.org/10.1038/nrc2772openalex-snapshot

Senescence in tumours: evidence from mice and humans

inferredcites →https://doi.org/10.1038/nrc3655openalex-snapshot

Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge

inferredcites →https://doi.org/10.1038/s41572-019-0064-5openalex-snapshot

Radiotherapy toxicity

inferredcites →https://doi.org/10.1056/nejmoa1508054openalex-snapshot

Germline Mutations in Predisposition Genes in Pediatric Cancer

inferredcites →https://doi.org/10.1073/pnas.0308531101openalex-snapshot

Metagenes and molecular pattern discovery using matrix factorization

inferredcites →https://doi.org/10.1073/pnas.0409130102openalex-snapshot

DNA damage-induced mitotic catastrophe is mediated by the Chk1-dependent mitotic exit DNA damage checkpoint

inferredcites →https://doi.org/10.1073/pnas.0506580102openalex-snapshot

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

inferredcites →https://doi.org/10.1073/pnas.1114033109openalex-snapshot

Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response

inferredcites →https://doi.org/10.1073/pnas.1616100114openalex-snapshot

Inhibition of radiation-induced glioblastoma invasion by genetic and pharmacological targeting of MDA-9/Syntenin

inferredcites →https://doi.org/10.1093/bioinformatics/btr032openalex-snapshot

Bambino: a variant detector and alignment viewer for next-generation sequencing data in the SAM/BAM format

inferredcites →https://doi.org/10.1093/bioinformatics/btu049openalex-snapshot

Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

inferredcites →https://doi.org/10.1093/jnci/djp148openalex-snapshot

Long-Term Outcomes Among Adult Survivors of Childhood Central Nervous System Malignancies in the Childhood Cancer Survivor Study

inferredcites →https://doi.org/10.1093/jnci/djx062openalex-snapshot

Loss of DNA Damage Response in Neuroblastoma and Utility of a PARP Inhibitor

inferredcites →https://doi.org/10.1093/nar/gku590openalex-snapshot

Genomic organization and evolution of double minutes/homogeneously staining regions withMYCamplification in human cancer

inferredcites →https://doi.org/10.1093/nar/gkx881openalex-snapshot

PARP2 controls double-strand break repair pathway choice by limiting 53BP1 accumulation at DNA damage sites and promoting end-resection

inferredcites →https://doi.org/10.1093/nar/gky1015openalex-snapshot

COSMIC: the Catalogue Of Somatic Mutations In Cancer

inferredcites →https://doi.org/10.1097/nen.0b013e3181257190openalex-snapshot

Unique Molecular Characteristics of Radiation-Induced Glioblastoma

inferredcites →https://doi.org/10.1101/gr.1239303openalex-snapshot

Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks

inferredcites →https://doi.org/10.1101/gr.134635.111openalex-snapshot

MuSiC: Identifying mutational significance in cancer genomes

inferredcites →https://doi.org/10.1111/his.13069openalex-snapshot

Radiation‐associated neoplasia: clinical, pathological and genomic correlates

inferredcites →https://doi.org/10.1111/j.0009-9163.2004.0234.xopenalex-snapshot

Mutations in the hMLH1 gene in Slovenian patients with gastric carcinoma

inferredcites →https://doi.org/10.1126/science.1241328openalex-snapshot

Targeted Therapy Resistance Mediated by Dynamic Regulation of Extrachromosomal Mutant EGFR DNA

inferredcites →https://doi.org/10.1158/0008-5472.can-12-0334openalex-snapshot

Sensitivity of Glioblastomas to Clinically Available MEK Inhibitors Is Defined by Neurofibromin 1 Deficiency

inferredcites →https://doi.org/10.1158/1078-0432.ccr-11-2489openalex-snapshot

Copy Number Gain of 1q25 Predicts Poor Progression-Free Survival for Pediatric Intracranial Ependymomas and Enables Patient Risk Stratification: A Prospective European Clinical Trial Cohort Analysis on Behalf of the Children's Cancer Leukaemia Group (CCLG), Société Française d'Oncologie…

inferredcites →https://doi.org/10.1158/1078-0432.ccr-14-2955openalex-snapshot

CDK4 Amplification Reduces Sensitivity to CDK4/6 Inhibition in Fusion-Positive Rhabdomyosarcoma

inferredcites →https://doi.org/10.1158/1538-7445.am2012-3350openalex-snapshot

Abstract 3350: Implications of the STAT6 pathway by interleukin-4 in prostate cancer

inferredcites →https://doi.org/10.1186/s40478-018-0570-9openalex-snapshot

Medulloblastoma therapy generates risk of a poorly-prognostic H3 wild-type subgroup of diffuse intrinsic pontine glioma: a report from the International DIPG Registry

inferredcites →https://doi.org/10.1200/jco.2008.21.1425openalex-snapshot

Late Mortality Among 5-Year Survivors of Childhood Cancer: A Summary From the Childhood Cancer Survivor Study

inferredcites →https://doi.org/10.1200/jco.2009.26.7252openalex-snapshot

Integrated Molecular Genetic Profiling of Pediatric High-Grade Gliomas Reveals Key Differences With the Adult Disease

inferredcites →https://doi.org/10.1200/jco.2010.30.2810openalex-snapshot

Definition of Disease-Risk Stratification Groups in Childhood Medulloblastoma Using Combined Clinical, Pathologic, and Molecular Variables

inferredcites →https://doi.org/10.1200/jco.2014.58.3922openalex-snapshot

BRAF Mutation and CDKN2A Deletion Define a Clinically Distinct Subgroup of Childhood Secondary High-Grade Glioma

inferredcites →https://doi.org/10.1200/jco.2015.66.1140openalex-snapshot

Association of Chromosome 1q Gain With Inferior Survival in Favorable-Histology Wilms Tumor: A Report From the Children’s Oncology Group

inferredcites →https://doi.org/10.1200/jco.2016.71.8726openalex-snapshot

Therapeutic and Prognostic Implications of BRAF V600E in Pediatric Low-Grade Gliomas

inferredcites →https://doi.org/10.3389/fonc.2017.00045openalex-snapshot

Therapeutic Targeting of Histone Modifications in Adult and Pediatric High-Grade Glioma

inferredcites →https://doi.org/10.3892/ol.2017.5812openalex-snapshot

Novel drugs in pediatric gliomas

inferredcites →https://doi.org/10.7554/elife.08153openalex-snapshot

Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1007/978-3-031-62017-1_10openalex-snapshot

Pediatric High Grade Glioma

inferred← citeshttps://doi.org/10.1093/noajnl/vdab109openalex-snapshot

Defining the molecular features of radiation-induced glioma: A systematic review and meta-analysis

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