On the public citation graph

Discovery of synthetic lethal interactions from large-scale pan-cancer perturbation screens

https://doi.org/10.1101/810374
0 signed · 36 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.
Claim with ORCID
Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.
See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1006/meth.2001.1262openalex-snapshot
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
inferredcites →https://doi.org/10.1016/j.bbrc.2010.03.165openalex-snapshot
Regulation of survivin by PI3K/Akt/p70S6K1 pathway
inferredcites →https://doi.org/10.1016/j.cell.2014.07.027openalex-snapshot
Predicting Cancer-Specific Vulnerability via Data-Driven Detection of Synthetic Lethality
inferredcites →https://doi.org/10.1016/j.cell.2017.07.005openalex-snapshot
Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening
inferredcites →https://doi.org/10.1016/j.celrep.2014.03.003openalex-snapshot
Recurrent Somatic Structural Variations Contribute to Tumorigenesis in Pediatric Osteosarcoma
inferredcites →https://doi.org/10.1016/j.celrep.2016.03.043openalex-snapshot
MTAP Deletions in Cancer Create Vulnerability to Targeting of the MAT2A/PRMT5/RIOK1 Axis
inferredcites →https://doi.org/10.1016/j.celrep.2016.08.010openalex-snapshot
Recurrent Loss of NFE2L2 Exon 2 Is a Mechanism for Nrf2 Pathway Activation in Human Cancers
inferredcites →https://doi.org/10.1016/j.dnarep.2013.04.004openalex-snapshot
PARP-mediated repair, homologous recombination, and back-up non-homologous end joining-like repair of single-strand nicks
inferredcites →https://doi.org/10.1038/378789a0openalex-snapshot
Identification of the breast cancer susceptibility gene BRCA2
inferredcites →https://doi.org/10.1038/nature03443openalex-snapshot
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
inferredcites →https://doi.org/10.1038/nature11003openalex-snapshot
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
inferredcites →https://doi.org/10.1038/nature12213openalex-snapshot
Mutational heterogeneity in cancer and the search for new cancer-associated genes
inferredcites →https://doi.org/10.1038/nature12912openalex-snapshot
Discovery and saturation analysis of cancer genes across 21 tumour types
inferredcites →https://doi.org/10.1038/ng.3168openalex-snapshot
Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes
inferredcites →https://doi.org/10.1038/nmeth1089openalex-snapshot
A probability-based approach for the analysis of large-scale RNAi screens
inferredcites →https://doi.org/10.1038/nrclinonc.2017.46openalex-snapshot
Exploiting synthetic lethality to improve cancer therapy
inferredcites →https://doi.org/10.1038/onc.2011.111openalex-snapshot
Roles of BIM induction and survivin downregulation in lapatinib-induced apoptosis in breast cancer cells with HER2 amplification
inferredcites →https://doi.org/10.1038/sj.onc.1206678openalex-snapshot
Roles of BRCA1 and BRCA2 in homologous recombination, DNA replication fidelity and the cellular response to ionizing radiation
inferredcites →https://doi.org/10.1089/dna.2006.0505openalex-snapshot
Molecular Pathogenesis of Osteosarcoma
inferredcites →https://doi.org/10.1101/gr.139469.112openalex-snapshot
GATA3 acts upstream of FOXA1 in mediating ESR1 binding by shaping enhancer accessibility
inferredcites →https://doi.org/10.1101/gr.143586.112openalex-snapshot
ATARiS: Computational quantification of gene suppression phenotypes from multisample RNAi screens
inferredcites →https://doi.org/10.1126/science.7545954openalex-snapshot
A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1
inferredcites →https://doi.org/10.1158/0008-5472.can-11-3417openalex-snapshot
Mre11-Dependent Degradation of Stalled DNA Replication Forks Is Prevented by BRCA2 and PARP1
inferredcites →https://doi.org/10.1158/1538-7445.am2012-2814openalex-snapshot
Abstract 2814: Potent and selective small molecule inhibitors of polo-like kinase 1: Biological characterization
inferredcites →https://doi.org/10.1182/blood-2011-01-313734openalex-snapshot
Synthetic lethality: exploiting the addiction of cancer to DNA repair
inferredcites →https://doi.org/10.1186/1476-4598-8-118openalex-snapshot
Sorafenib blocks tumour growth, angiogenesis and metastatic potential in preclinical models of osteosarcoma through a mechanism potentially involving the inhibition of ERK1/2, MCL-1 and ezrin pathways
inferredcites →https://doi.org/10.18637/jss.v042.i07openalex-snapshot
Multivariate and Propensity Score Matching Software with Automated Balance Optimization: The Matching Package for R

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1038/s41598-023-42992-4openalex-snapshot
SL-scan identifies synthetic lethal interactions in cancer using metabolic networks
inferred← citeshttps://doi.org/10.1038/s41598-024-51453-5openalex-snapshot
Uncovering hidden cancer self-dependencies through analysis of shRNA-level dependency scores
inferred← citeshttps://doi.org/10.1038/s42003-022-03296-xopenalex-snapshot
GATA3 and MDM2 are synthetic lethal in estrogen receptor-positive breast cancers
inferred← citeshttps://doi.org/10.1093/nar/gkab627openalex-snapshot
Systematic identification of novel cancer genes through analysis of deep shRNA perturbation screens
inferred← citeshttps://doi.org/10.1101/2020.05.18.101998openalex-snapshot
GATA3 and MDM2 are synthetic lethal in estrogen receptor-positive breast cancers
inferred← citeshttps://doi.org/10.1101/2022.07.07.499118openalex-snapshot
SLIDE-VIP: a comprehensive, cell line- and patient-based framework for synthetic lethality prediction in DNA damage repair, chromatin remodeling and cell cycle
inferred← citeshttps://doi.org/10.1101/2023.12.03.569803openalex-snapshot
Synthetic Lethality Screening with Recursive Feature Machines
inferred← citeshttps://doi.org/10.1101/807248openalex-snapshot
Systematic Identification of Novel Cancer Genes through Analysis of Deep shRNA Perturbation Screens
inferred← citeshttps://doi.org/10.3389/fgene.2022.961611openalex-snapshot
Synthetic lethal gene pairs: Experimental approaches and predictive models
Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.