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Biological sex and age shape melanoma tumour evolution

https://doi.org/10.1101/828038
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1016/j.cell.2012.04.023openalex-snapshot
The Life History of 21 Breast Cancers
inferredcites →https://doi.org/10.1016/j.cell.2015.05.044openalex-snapshot
Genomic Classification of Cutaneous Melanoma
inferredcites →https://doi.org/10.1016/j.cell.2019.03.001openalex-snapshot
A Compendium of Mutational Signatures of Environmental Agents
inferredcites →https://doi.org/10.1016/s0140-6736(18)31559-9openalex-snapshot
Melanoma
inferredcites →https://doi.org/10.1038/nature07943openalex-snapshot
The cancer genome
inferredcites →https://doi.org/10.1038/nature12477openalex-snapshot
Signatures of mutational processes in human cancer
inferredcites →https://doi.org/10.1038/nature13298openalex-snapshot
Ultraviolet radiation accelerates BRAF-driven melanomagenesis by targeting TP53
inferredcites →https://doi.org/10.1038/nature16166openalex-snapshot
Substantial contribution of extrinsic risk factors to cancer development
inferredcites →https://doi.org/10.1038/nature19768openalex-snapshot
Tissue-specific mutation accumulation in human adult stem cells during life
inferredcites →https://doi.org/10.1038/ng.3441openalex-snapshot
Clock-like mutational processes in human somatic cells
inferredcites →https://doi.org/10.1038/nrc.2016.37openalex-snapshot
From melanocytes to melanomas
inferredcites →https://doi.org/10.1038/s41467-020-17359-2openalex-snapshot
Sex differences in oncogenic mutational processes
inferredcites →https://doi.org/10.1038/s41588-018-0312-8openalex-snapshot
Tumor mutational load predicts survival after immunotherapy across multiple cancer types
inferredcites →https://doi.org/10.1073/pnas.1905722116openalex-snapshot
Cell division rates decrease with age, providing a potential explanation for the age-dependent deceleration in cancer incidence
inferredcites →https://doi.org/10.1093/jnci/95.11.806openalex-snapshot
Melanocytic Nevi, Solar Keratoses, and Divergent Pathways to Cutaneous Melanoma
inferredcites →https://doi.org/10.1093/jnci/djv221openalex-snapshot
Gender Disparity and Mutation Burden in Metastatic Melanoma
inferredcites →https://doi.org/10.1101/528968openalex-snapshot
Sex Differences in Oncogenic Mutational Processes
inferredcites →https://doi.org/10.1126/science.1260825openalex-snapshot
Variation in cancer risk among tissues can be explained by the number of stem cell divisions
inferredcites →https://doi.org/10.1126/science.aab3388openalex-snapshot
Stem cells and healthy aging
inferredcites →https://doi.org/10.1158/1078-0432.ccr-18-1116openalex-snapshot
Age Correlates with Response to Anti-PD1, Reflecting Age-Related Differences in Intratumoral Effector and Regulatory T-Cell Populations
inferredcites →https://doi.org/10.1186/s13059-016-0893-4openalex-snapshot
deconstructSigs: delineating mutational processes in single tumors distinguishes DNA repair deficiencies and patterns of carcinoma evolution
inferredcites →https://doi.org/10.1200/jco.2001.19.16.3622openalex-snapshot
Prognostic Factors Analysis of 17,600 Melanoma Patients: Validation of the American Joint Committee on Cancer Melanoma Staging System
inferredcites →https://doi.org/10.1245/s10434-013-3100-9openalex-snapshot
Age as a Prognostic Factor in Patients with Localized Melanoma and Regional Metastases
inferredcites →https://doi.org/10.1245/s10434-015-4538-8openalex-snapshot
Older Age is Associated with a Higher Incidence of Melanoma Death but a Lower Incidence of Sentinel Lymph Node Metastasis in the SEER Databases (2003–2011)
inferredcites →https://doi.org/10.7314/apjcp.2016.17.2.835openalex-snapshot
Evaluation of Machine Learning Algorithm Utilization for Lung Cancer Classification Based on Gene Expression Levels

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1158/1078-0432.ccr-20-4261openalex-snapshot
Female Immunity Protects from Cutaneous Squamous Cell Carcinoma
inferred← citeshttps://doi.org/10.3389/fceld.2026.1821035openalex-snapshot
Challenges in drug efficacy and toxicity screening with 3D bioprinted melanoma models
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