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Ebselen attenuates mycobacterial virulence through inhibition of ESX-1 secretion
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/jbt.20189openalex-snapshot
Evaluation of the antimicrobial activity of ebselen: Role of the yeast plasma membrane H+‐ATPase
inferredcites →https://doi.org/10.1002/prot.24351openalex-snapshot
Crystal structure of the N-terminal domain of EccA 1 ATPase from the ESX-1 secretion system of Mycobacterium tuberculosis
inferredcites →https://doi.org/10.1007/978-1-62703-764-8_11openalex-snapshot
FX Cloning: A Simple and Robust High-Throughput Cloning Method for Protein Expression
inferredcites →https://doi.org/10.1007/s00018-016-2374-zopenalex-snapshot
Assessing heterogeneity in oligomeric AAA+ machines
inferredcites →https://doi.org/10.1007/s11033-014-3417-xopenalex-snapshot
Ebselen, a promising antioxidant drug: mechanisms of action and targets of biological pathways
inferredcites →https://doi.org/10.1016/j.bbagen.2016.03.013openalex-snapshot
Ebselen and analogs as inhibitors of Bacillus anthracis thioredoxin reductase and bactericidal antibacterials targeting Bacillus species, Staphylococcus aureus and Mycobacterium tuberculosis
inferredcites →https://doi.org/10.1016/j.cell.2007.05.059openalex-snapshot
M. tuberculosis and M. leprae Translocate from the Phagolysosome to the Cytosol in Myeloid Cells
inferredcites →https://doi.org/10.1016/j.cell.2015.03.040openalex-snapshot
Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion
inferredcites →https://doi.org/10.1016/j.chom.2014.09.008openalex-snapshot
Anticytolytic Screen Identifies Inhibitors of Mycobacterial Virulence Protein Secretion
inferredcites →https://doi.org/10.1016/j.jcf.2020.02.014openalex-snapshot
Ebselen attenuates tobramycin-induced ototoxicity in mice
inferredcites →https://doi.org/10.1016/j.molcel.2018.03.009openalex-snapshot
Galectins Control mTOR in Response to Endomembrane Damage
inferredcites →https://doi.org/10.1016/j.tibs.2003.10.007openalex-snapshot
TPR proteins: the versatile helix
inferredcites →https://doi.org/10.1016/s0140-6736(17)31791-9openalex-snapshot
Safety and efficacy of ebselen for the prevention of noise-induced hearing loss: a randomised, double-blind, placebo-controlled, phase 2 trial
inferredcites →https://doi.org/10.1021/ac1011602openalex-snapshot
Study of Highly Selective and Efficient Thiol Derivatization Using Selenium Reagents by Mass Spectrometry
inferredcites →https://doi.org/10.1021/bi901546eopenalex-snapshot
The Selenazal Drug Ebselen Potently Inhibits Indoleamine 2,3-Dioxygenase by Targeting Enzyme Cysteine Residues
inferredcites →https://doi.org/10.1021/pr500484wopenalex-snapshot
Correlation of Phenotypic Profiles Using Targeted Proteomics Identifies Mycobacterial Esx-1 Substrates
inferredcites →https://doi.org/10.1038/ncomms2320openalex-snapshot
A safe lithium mimetic for bipolar disorder
inferredcites →https://doi.org/10.1038/ncomms3748openalex-snapshot
Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen
inferredcites →https://doi.org/10.1038/ncomms3798openalex-snapshot
A facile soft-template synthesis of mesoporous polymeric and carbonaceous nanospheres
inferredcites →https://doi.org/10.1038/nsmb.1501openalex-snapshot
The 'glutamate switch' provides a link between ATPase activity and ligand binding in AAA+ proteins
inferredcites →https://doi.org/10.1038/srep27459openalex-snapshot
IVA cloning: A single-tube universal cloning system exploiting bacterial In Vivo Assembly
inferredcites →https://doi.org/10.1046/j.1365-2958.2002.03237.xopenalex-snapshot
Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti
inferredcites →https://doi.org/10.1046/j.1365-2958.2003.03844.xopenalex-snapshot
Individual RD1‐region genes are required for export of ESAT‐6/CFP‐10 and for virulence of Mycobacterium tuberculosis
inferredcites →https://doi.org/10.1073/pnas.0504922102openalex-snapshot
Mutually dependent secretion of proteins required for mycobacterial virulence
inferredcites →https://doi.org/10.1073/pnas.1620133114openalex-snapshot
Mycobacterial ESX-1 secretion system mediates host cell lysis through bacterium contact-dependent gross membrane disruptions
inferredcites →https://doi.org/10.1073/pnas.1635213100openalex-snapshot
The primary mechanism of attenuation of bacillus Calmette–Guérin is a loss of secreted lytic function required for invasion of lung interstitial tissue
inferredcites →https://doi.org/10.1073/pnas.2235593100openalex-snapshot
Acute infection and macrophage subversion by Mycobacterium tuberculosis require a specialized secretion system
inferredcites →https://doi.org/10.1074/jbc.m807144200openalex-snapshot
Characterization of Rv3868, an Essential Hypothetical Protein of the ESX-1 Secretion System in Mycobacterium tuberculosis
inferredcites →https://doi.org/10.1086/345862openalex-snapshot
Deletion of RD1 fromMycobacterium tuberculosisMimics Bacille Calmette‐Guérin Attenuation
inferredcites →https://doi.org/10.1096/fj.12-223305openalex-snapshot
Inhibition of bacterial thioredoxin reductase: an antibiotic mechanism targeting bacteria lacking glutathione
inferredcites →https://doi.org/10.1111/cmi.12622openalex-snapshot
Perspectives on mycobacterial vacuole-to-cytosol translocation: the importance of cytosolic access
inferredcites →https://doi.org/10.1111/j.1365-2958.2004.04261.xopenalex-snapshot
A mycobacterial virulence gene cluster extending RD1 is required for cytolysis, bacterial spreading and ESAT‐6 secretion
inferredcites →https://doi.org/10.1126/science.284.5419.1520openalex-snapshot
Comparative Genomics of BCG Vaccines by Whole-Genome DNA Microarray
inferredcites →https://doi.org/10.1128/aac.00719-15openalex-snapshot
The Carbonic Anhydrase Inhibitor Ethoxzolamide Inhibits the Mycobacterium tuberculosis PhoPR Regulon and Esx-1 Secretion and Attenuates Virulence
inferredcites →https://doi.org/10.1128/iai.00614-08openalex-snapshot
Evidence for Pore Formation in Host Cell Membranes by ESX-1-Secreted ESAT-6 and Its Role in Mycobacterium marinum Escape from the Vacuole
inferredcites →https://doi.org/10.1128/iai.61.6.2708-2712.1993openalex-snapshot
Expression of contact-dependent cytolytic activity by Mycobacterium tuberculosis and isolation of the genomic locus that encodes the activity
inferredcites →https://doi.org/10.1128/iai.72.5.3031-3037.2004openalex-snapshot
Protection Elicited by a Double Leucine and Pantothenate Auxotroph of Mycobacterium tuberculosis in Guinea Pigs
inferredcites →https://doi.org/10.1128/iai.74.1.88-98.2006openalex-snapshot
Dissection of ESAT-6 System 1 of Mycobacterium tuberculosis and Impact on Immunogenicity and Virulence
inferredcites →https://doi.org/10.1128/jb.00469-07openalex-snapshot
ESAT-6 from Mycobacterium tuberculosis Dissociates from Its Putative Chaperone CFP-10 under Acidic Conditions and Exhibits Membrane-Lysing Activity
inferredcites →https://doi.org/10.1128/jb.178.5.1274-1282.1996openalex-snapshot
Molecular analysis of genetic differences between Mycobacterium bovis BCG and virulent M. bovis
inferredcites →https://doi.org/10.1183/09031936.00044812openalex-snapshot
Hearing loss in patients on treatment for drug-resistant tuberculosis
inferredcites →https://doi.org/10.1242/dmm.013854openalex-snapshot
ModelingMycobacterium tuberculosisearly granuloma formation in experimental human lung tissue
inferredcites →https://doi.org/10.1371/journal.pbio.0020367openalex-snapshot
Tuberculous Granuloma Formation Is Enhanced by a Mycobacterium Virulence Determinant
inferredcites →https://doi.org/10.1371/journal.pone.0233252openalex-snapshot
Mycobacterium marinum phthiocerol dimycocerosates enhance macrophage phagosomal permeabilization and membrane damage
inferredcites →https://doi.org/10.1371/journal.ppat.1000507openalex-snapshot
Systematic Genetic Nomenclature for Type VII Secretion Systems
inferredcites →https://doi.org/10.1371/journal.ppat.1002507openalex-snapshot
Phagosomal Rupture by Mycobacterium tuberculosis Results in Toxicity and Host Cell Death
inferredcites →https://doi.org/10.3389/fmolb.2017.00020openalex-snapshot
Rubisco Activases: AAA+ Chaperones Adapted to Enzyme Repair
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1007/s15010-026-02909-5openalex-snapshot
Mechanistic and molecular insights into emerging anti-virulence therapeutics
inferred← citeshttps://doi.org/10.1111/febs.70084openalex-snapshot
Countering the effector functions of ESAT ‐6 protein in Mycobacterium tuberculosis: strategies for developing antimycobacterial therapeutics
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