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Facile Accelerated Specific Therapeutic (FAST) Platform to Counter Multidrug-Resistant Bacteria

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Association of Broad- vs Narrow-Spectrum Antibiotics With Treatment Failure, Adverse Events, and Quality of Life in Children With Acute Respiratory Tract Infections

inferredcites →https://doi.org/10.1002/phar.1868openalex-snapshot

Past, Present, and Future of Antibacterial Economics: Increasing Bacterial Resistance, Limited Antibiotic Pipeline, and Societal Implications

inferredcites →https://doi.org/10.1007/bf00332630openalex-snapshot

Translation rates and misreading characteristics of rpsD mutants in Escherichia coli

inferredcites →https://doi.org/10.1007/s00253-009-2387-8openalex-snapshot

Peptide nucleic acids (PNAs) antisense effect to bacterial growth and their application potentiality in biotechnology

inferredcites →https://doi.org/10.1007/s00253-017-8671-0openalex-snapshot

Advances in therapeutic bacterial antisense biotechnology

inferredcites →https://doi.org/10.1007/s12275-014-4087-zopenalex-snapshot

Phage lysis: Three steps, three choices, one outcome

inferredcites →https://doi.org/10.1016/0006-2952(94)90171-6openalex-snapshot

Stability of peptide nucleic acids in human serum and cellular extracts

inferredcites →https://doi.org/10.1016/0092-8674(82)90085-xopenalex-snapshot

The SOS regulatory system of Escherichia coli

inferredcites →https://doi.org/10.1016/j.biomaterials.2011.09.075openalex-snapshot

Antisense inhibition of gene expression and growth in gram-negative bacteria by cell-penetrating peptide conjugates of peptide nucleic acids targeted to rpoD gene

inferredcites →https://doi.org/10.1016/j.bmcl.2018.07.037openalex-snapshot

Antimicrobial synergy between mRNA targeted peptide nucleic acid and antibiotics in E. coli

inferredcites →https://doi.org/10.1016/j.jconrel.2016.01.005openalex-snapshot

Nanotechnology for delivery of peptide nucleic acids (PNAs)

inferredcites →https://doi.org/10.1016/j.mib.2016.05.017openalex-snapshot

Antisense antimicrobial therapeutics

inferredcites →https://doi.org/10.1016/s0021-9258(18)89069-xopenalex-snapshot

Folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase. Cloning and high expression of the Escherichia coli folC gene and purification and properties of the gene product.

inferredcites →https://doi.org/10.1016/s0140-6736(00)90015-1openalex-snapshot

An antibiotic policy to prevent emergence of resistant bacilli

inferredcites →https://doi.org/10.1016/s0169-409x(02)00182-5openalex-snapshot

Cellular delivery of peptide nucleic acid (PNA)

inferredcites →https://doi.org/10.1016/s1098-3597(03)90025-1openalex-snapshot

Antibiotics and collateral damage

inferredcites →https://doi.org/10.1016/s1473-3099(17)30753-3openalex-snapshot

Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis

inferredcites →https://doi.org/10.1021/acsinfecdis.5b00042openalex-snapshot

Sequence-Specific Peptide Nucleic Acid-Based Antisense Inhibitors of TEM-1 β-Lactamase and Mechanism of Adaptive Resistance

inferredcites →https://doi.org/10.1021/acssynbio.9b00321openalex-snapshot

Construction of Two-Input Logic Gates Using Transcriptional Interference

inferredcites →https://doi.org/10.1038/359744a0openalex-snapshot

The E. coli ffh gene is necessary for viability and efficient protein export

inferredcites →https://doi.org/10.1038/44593openalex-snapshot

Extraintestinal dissemination of Salmonella by CD18-expressing phagocytes

inferredcites →https://doi.org/10.1038/86753openalex-snapshot

Bactericidal antisense effects of peptide–PNA conjugates

inferredcites →https://doi.org/10.1038/ja.2012.27openalex-snapshot

Thoughts and facts about antibiotics: Where we are now and where we are heading

inferredcites →https://doi.org/10.1038/msb4100050openalex-snapshot

Construction of Escherichia coli K‐12 in‐frame, single‐gene knockout mutants: the Keio collection

inferredcites →https://doi.org/10.1038/ncomms5352openalex-snapshot

Genome-wide analysis captures the determinants of the antibiotic cross-resistance interaction network

inferredcites →https://doi.org/10.1038/nm1145openalex-snapshot

Antibacterial resistance worldwide: causes, challenges and responses

inferredcites →https://doi.org/10.1038/nmeth.1923openalex-snapshot

Fast gapped-read alignment with Bowtie 2

inferredcites →https://doi.org/10.1038/nrmicro.2017.20openalex-snapshot

Assembly, structure, function and regulation of type III secretion systems

inferredcites →https://doi.org/10.1046/j.1365-2958.2000.01826.xopenalex-snapshot

Identification of additional genes belonging to the LexA regulon in Escherichia coli

inferredcites →https://doi.org/10.1073/pnas.0805965105openalex-snapshot

Accelerated evolution of resistance in multidrug environments

inferredcites →https://doi.org/10.1073/pnas.95.5.2073openalex-snapshot

Inhibition of translation and bacterial growth by peptide nucleic acid targeted to ribosomal RNA

inferredcites →https://doi.org/10.1074/jbc.m213060200openalex-snapshot

Global Gene Expression Profiling in Escherichia coli K12

inferredcites →https://doi.org/10.1074/jbc.m414030200openalex-snapshot

Global Gene Expression Profiling in Escherichia coli K12

inferredcites →https://doi.org/10.1089/cmb.2012.0021openalex-snapshot

SPAdes: A New Genome Assembly Algorithm and Its Applications to Single-Cell Sequencing

inferredcites →https://doi.org/10.1093/bib/bbs017openalex-snapshot

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

inferredcites →https://doi.org/10.1093/bioinformatics/btp352openalex-snapshot

The Sequence Alignment/Map format and SAMtools

inferredcites →https://doi.org/10.1093/bioinformatics/btq033openalex-snapshot

BEDTools: a flexible suite of utilities for comparing genomic features

inferredcites →https://doi.org/10.1093/bioinformatics/btu153openalex-snapshot

Prokka: rapid prokaryotic genome annotation

inferredcites →https://doi.org/10.1093/bioinformatics/btu170openalex-snapshot

Trimmomatic: a flexible trimmer for Illumina sequence data

inferredcites →https://doi.org/10.1093/jac/dki173openalex-snapshot

Antimicrobial synergy between mRNA- and protein-level inhibitors

inferredcites →https://doi.org/10.1093/jac/dkw384openalex-snapshot

Antimicrobial activity of antisense peptide–peptide nucleic acid conjugates against non-typeableHaemophilus influenzaein planktonic and biofilm forms

inferredcites →https://doi.org/10.1093/nar/26.21.5004openalex-snapshot

A formula for thermal stability (Tm) prediction of PNA/DNA duplexes

inferredcites →https://doi.org/10.1093/nar/gkq665openalex-snapshot

A domain insertion in Escherichia coli GyrB adopts a novel fold that plays a critical role in gyrase function

inferredcites →https://doi.org/10.1093/nar/gku1003openalex-snapshot

STRING v10: protein–protein interaction networks, integrated over the tree of life

inferredcites →https://doi.org/10.1093/nar/gkv1156openalex-snapshot

RegulonDB version 9.0: high-level integration of gene regulation, coexpression, motif clustering and beyond

inferredcites →https://doi.org/10.1093/nar/gkw1003openalex-snapshot

The EcoCyc database: reflecting new knowledge aboutEscherichia coliK-12

inferredcites →https://doi.org/10.1098/rsbl.2006.0478openalex-snapshot

Enhancement of bacterial competitive fitness by apramycin resistance plasmids from non-pathogenicEscherichia coli

inferredcites →https://doi.org/10.1099/mic.0.26306-0openalex-snapshot

The curli biosynthesis regulator CsgD co-ordinates the expression of both positive and negative determinants for biofilm formation in Escherichia coli

inferredcites →https://doi.org/10.1101/gr.074492.107openalex-snapshot

Velvet: Algorithms for de novo short read assembly using de Bruijn graphs

inferredcites →https://doi.org/10.1111/j.1365-2958.1995.mmi_18010045.xopenalex-snapshot

Insertion of inverted Ter sites into the terminus region of the Escherichia coli chromosome delays completion of DNA replication and disrupts the cell cycle

inferredcites →https://doi.org/10.1111/j.1365-2958.1995.tb02390.xopenalex-snapshot

Genes acrA and acrB encode a stress‐induced efflux system of Escherichia coli

inferredcites →https://doi.org/10.1111/j.1744-7348.1939.tb06990.xopenalex-snapshot

THE TOXICITY OF POISONS APPLIED JOINTLY1

inferredcites →https://doi.org/10.1126/science.1962210openalex-snapshot

Sequence-Selective Recognition of DNA by Strand Displacement with a Thymine-Substituted Polyamide

inferredcites →https://doi.org/10.1126/science.280.5363.602openalex-snapshot

Supramolecular Structure of the Salmonella typhimurium Type III Protein Secretion System

inferredcites →https://doi.org/10.1128/aac.00709-06openalex-snapshot

Inhibition of Gene Expression and Growth by Antisense Peptide Nucleic Acids in a Multiresistant β-Lactamase-Producing Klebsiella pneumoniae Strain

inferredcites →https://doi.org/10.1128/aac.01310-13openalex-snapshot

ARG-ANNOT, a New Bioinformatic Tool To Discover Antibiotic Resistance Genes in Bacterial Genomes

inferredcites →https://doi.org/10.1128/aac.01437-12openalex-snapshot

Targeting Essential Genes in Salmonella enterica Serovar Typhimurium with Antisense Peptide Nucleic Acid

inferredcites →https://doi.org/10.1128/aac.49.1.249-255.2005openalex-snapshot

Antisense Phosphorodiamidate Morpholino Oligomer Length and Target Position Effects on Gene-Specific Inhibition inEscherichia coli

inferredcites →https://doi.org/10.1371/journal.pone.0089082openalex-snapshot

Species-Selective Killing of Bacteria by Antimicrobial Peptide-PNAs

inferredcites →https://doi.org/10.1371/journal.pone.0133492openalex-snapshot

Search Engine for Antimicrobial Resistance: A Cloud Compatible Pipeline and Web Interface for Rapidly Detecting Antimicrobial Resistance Genes Directly from Sequence Data

inferredcites →https://doi.org/10.3389/fmicb.2019.01032openalex-snapshot

PNA Length Restriction of Antibacterial Activity of Peptide-PNA Conjugates in Escherichia coli Through Effects of the Inner Membrane

inferredcites →https://doi.org/10.4014/jmb.0903.04018openalex-snapshot

Highly sensitive PNA Array Platform Technology for Single Nucleotide Mismatch Discrimination

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1021/acsbiomaterials.2c00510openalex-snapshot

Nanoligomers Targeting Human miRNA for the Treatment of Severe COVID-19 Are Safe and Nontoxic in Mice

inferred← citeshttps://doi.org/10.1101/2019.12.16.878389openalex-snapshot

Transcriptome-based design of antisense inhibitors re-sensitizes CRE E. coli to carbapenems

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