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Differential activation of G-protein-mediated signalling by synthetic cannabinoid receptor agonists
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Outgoing claims: the papers this work cites, builds on, or argues with.
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Blockade of Effects of Smoked Marijuana by the CB1-Selective Cannabinoid Receptor Antagonist SR141716
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The Chemistry and Pharmacology of Synthetic Cannabinoid Receptor Agonists as New Psychoactive Substances: Origins
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The Chemistry and Pharmacology of Synthetic Cannabinoid Receptor Agonist New Psychoactive Substances: Evolution
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Pharmacological evaluation of synthetic cannabinoids identified as constituents of spice
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Pharmacological evaluation of new constituents of “Spice”: synthetic cannabinoids based on indole, indazole, benzimidazole and carbazole scaffolds
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SR141716A, a potent and selective antagonist of the brain cannabinoid receptor
inferredcites →https://doi.org/10.1016/j.bcp.2016.11.014openalex-snapshot
Functional selectivity at G-protein coupled receptors: Advancing cannabinoid receptors as drug targets
inferredcites →https://doi.org/10.1016/j.bcp.2019.08.025openalex-snapshot
Insights into biased signaling at cannabinoid receptors: synthetic cannabinoid receptor agonists
inferredcites →https://doi.org/10.1016/j.cell.2018.11.040openalex-snapshot
Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex
inferredcites →https://doi.org/10.1016/j.drugalcdep.2017.07.029openalex-snapshot
Synthetic cannabinoids found in “spice” products alter body temperature and cardiovascular parameters in conscious male rats
inferredcites →https://doi.org/10.1016/j.ejphar.2018.01.043openalex-snapshot
Analysis of the pharmacological properties of JWH-122 isomers and THJ-2201, RCS-4 and AB-CHMINACA in HEK293T cells and hippocampal neurons
inferredcites →https://doi.org/10.1016/j.forsciint.2015.12.046openalex-snapshot
Synthetic cannabinoid drug use as a cause or contributory cause of death
inferredcites →https://doi.org/10.1016/j.forsciint.2019.03.007openalex-snapshot
Cannabis as a cause of death: A review
inferredcites →https://doi.org/10.1016/j.neuropharm.2015.02.008openalex-snapshot
Novel halogenated derivates of JWH-018: Behavioral and binding studies in mice
inferredcites →https://doi.org/10.1016/j.neuropharm.2016.07.016openalex-snapshot
Evaluation of first generation synthetic cannabinoids on binding at non-cannabinoid receptors and in a battery of in vivo assays in mice
inferredcites →https://doi.org/10.1016/j.taap.2017.10.007openalex-snapshot
Synthetic cannabinoid AM2201 induces seizures: Involvement of cannabinoid CB 1 receptors and glutamatergic transmission
inferredcites →https://doi.org/10.1016/s0014-2999(01)01243-2openalex-snapshot
Assessment of the role of CB1 receptors in cannabinoid anticonvulsant effects
inferredcites →https://doi.org/10.1016/s0022-3565(24)37876-0openalex-snapshot
Dual Activation and Inhibition of Adenylyl Cyclase by Cannabinoid Receptor Agonists: Evidence for Agonist-Specific Trafficking of Intracellular Responses
inferredcites →https://doi.org/10.1021/acs.analchem.6b02600openalex-snapshot
Detection and Activity Profiling of Synthetic Cannabinoids and Their Metabolites with a Newly Developed Bioassay
inferredcites →https://doi.org/10.1021/acs.chemrev.5b00411openalex-snapshot
Medicinal Chemistry, Pharmacology, and Potential Therapeutic Benefits of Cannabinoid CB2Receptor Agonists
inferredcites →https://doi.org/10.1021/acschemneuro.6b00137openalex-snapshot
Pharmacology of Valinate andtert-Leucinate Synthetic Cannabinoids 5F-AMBICA, 5F-AMB, 5F-ADB, AMB-FUBINACA, MDMB-FUBINACA, MDMB-CHMICA, and Their Analogues
inferredcites →https://doi.org/10.1021/acschemneuro.9b00429openalex-snapshot
Do Toxic Synthetic Cannabinoid Receptor Agonists Have Signature in Vitro Activity Profiles? A Case Study of AMB-FUBINACA
inferredcites →https://doi.org/10.1021/acsptsci.9b00069openalex-snapshot
Assessment of Biased Agonism among Distinct Synthetic Cannabinoid Receptor Agonist Scaffolds
inferredcites →https://doi.org/10.1038/ncomms5767openalex-snapshot
Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations
inferredcites →https://doi.org/10.1038/s41598-017-10447-2openalex-snapshot
Natural (∆9-THC) and synthetic (JWH-018) cannabinoids induce seizures by acting through the cannabinoid CB1 receptor
inferredcites →https://doi.org/10.1046/j.1440-1681.1999.03049.xopenalex-snapshot
OPIOID RECEPTOR SIGNALLING MECHANISMS
inferredcites →https://doi.org/10.1056/nejmoa1610300openalex-snapshot
“Zombie” Outbreak Caused by the Synthetic Cannabinoid AMB-FUBINACA in New York
inferredcites →https://doi.org/10.1056/nejmp1505328openalex-snapshot
Synthetic Cannabinoid–Related Illnesses and Deaths
inferredcites →https://doi.org/10.1073/pnas.0509588102openalex-snapshot
The cannabinoid agonist WIN55,212-2 increases intracellular calcium via CB 1 receptor coupling to G q/11 G proteins
inferredcites →https://doi.org/10.1073/pnas.1113645108openalex-snapshot
Structural flexibility of the Gαs α-helical domain in the β 2 -adrenoceptor Gs complex
inferredcites →https://doi.org/10.1074/jbc.m114.557025openalex-snapshot
Type 1 Cannabinoid Receptor Ligands Display Functional Selectivity in a Cell Culture Model of Striatal Medium Spiny Projection Neurons
inferredcites →https://doi.org/10.1074/jbc.m609695200openalex-snapshot
Use of a cAMP BRET Sensor to Characterize a Novel Regulation of cAMP by the Sphingosine 1-Phosphate/G13 Pathway
inferredcites →https://doi.org/10.1111/bph.12329openalex-snapshot
Real‐time characterization of cannabinoid receptor 1 ( CB 1) allosteric modulators reveals novel mechanism of action
inferredcites →https://doi.org/10.1111/bph.13866openalex-snapshot
Gαssignalling of the CB1receptor and the influence of receptor number
inferredcites →https://doi.org/10.1111/bph.13882openalex-snapshot
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview
inferredcites →https://doi.org/10.1111/bph.14829openalex-snapshot
In vitro determination of the efficacy of illicit synthetic cannabinoids at CB 1 receptors
inferredcites →https://doi.org/10.1111/j.1476-5381.2010.00773.xopenalex-snapshot
Neuroprotective potential of CB1receptor agonists in anin vitromodel of Huntington's disease
inferredcites →https://doi.org/10.1111/j.1476-5381.2012.02223.xopenalex-snapshot
New concepts in pharmacological efficacy at 7 TM receptors: IUPHAR R eview 2
inferredcites →https://doi.org/10.1124/jpet.110.173948openalex-snapshot
Functional Selectivity and Biased Receptor Signaling
inferredcites →https://doi.org/10.1124/jpet.115.225326openalex-snapshot
AB-CHMINACA, AB-PINACA, and FUBIMINA: Affinity and Potency of Novel Synthetic Cannabinoids in Producing Δ9-Tetrahydrocannabinol–Like Effects in Mice
inferredcites →https://doi.org/10.1124/jpet.116.238717openalex-snapshot
Thermolytic Degradation of Synthetic Cannabinoids: Chemical Exposures and Pharmacological Consequences
inferredcites →https://doi.org/10.1124/jpet.117.246983openalex-snapshot
Molecular and Behavioral Pharmacological Characterization of Abused Synthetic Cannabinoids MMB- and MDMB-FUBINACA, MN-18, NNEI, CUMYL-PICA, and 5-Fluoro-CUMYL-PICA
inferredcites →https://doi.org/10.1124/jpet.118.251157openalex-snapshot
Convulsant Effects of Abused Synthetic Cannabinoids JWH-018 and 5F-AB-PINACA Are Mediated by Agonist Actions at CB1 Receptors in Mice
inferredcites →https://doi.org/10.1124/mol.104.003558openalex-snapshot
Chemically Distinct Ligands Promote Differential CB1 Cannabinoid Receptor-Gi Protein Interactions
inferredcites →https://doi.org/10.1177/1087057113501391openalex-snapshot
A Real-Time, Fluorescence-Based Assay for Measuring µ-Opioid Receptor Modulation of Adenylyl Cyclase Activity in Chinese Hamster Ovary Cells
inferredcites →https://doi.org/10.1517/13543770903436505openalex-snapshot
Latest advances in cannabinoid receptor agonists
inferredcites →https://doi.org/10.1523/jneurosci.17-14-05327.1997openalex-snapshot
Concurrent Stimulation of Cannabinoid CB1 and Dopamine D2 Receptors Augments cAMP Accumulation in Striatal Neurons: Evidence for a GsLinkage to the CB1 Receptor
inferredcites →https://doi.org/10.18356/3a4c2e67-enopenalex-snapshot
Global overview of drug demand and supply
inferredcites →https://doi.org/10.3389/fphar.2019.00350openalex-snapshot
Cannabinoid CB1 and CB2 Receptor-Mediated Arrestin Translocation: Species, Subtype, and Agonist-Dependence
inferredcites →https://doi.org/10.3389/fphar.2019.00595openalex-snapshot
CUMYL-4CN-BINACA Is an Efficacious and Potent Pro-Convulsant Synthetic Cannabinoid Receptor Agonist
inferredcites →https://doi.org/10.7717/peerj.7733openalex-snapshot
Brodifacoum does not modulate human cannabinoid receptor-mediated hyperpolarization of AtT20 cells or inhibition of adenylyl cyclase in HEK 293 cells
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