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O- Acyl Sugars Protect a Wild Tobacco from Both Native Fungal Pathogens and a Specialist Herbivore

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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GUS fusions: beta‐glucuronidase as a sensitive and versatile gene fusion marker in higher plants.
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Rapid characterization of the sucrose esters from oriental tobacco using liquid chromatography/ion trap mass spectrometry
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Aphid deterrence by glucose esters in glandular trichome exudate of the wild tomato,Lycopersicon pennellii
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Up in smoke: II. Germination ofNicotiana attenuata in response to smoke-derived cues and nutrients in burned and unburned soils
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Metabolic costs of terpenoid accumulation in higher plants
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Agrobacterium-mediated transformation of Nicotiana attenuata, a model ecological expression system
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Different elongation pathways in the biosynthesis of acyl groups of trichome exudate sugar esters from various solanaceous plants
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Plant chemical defense against herbivores and pathogens: generalized defense or trade-offs?
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Significance of flavonoids in plant resistance: a review
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Biological Activity of Acyl Glucose Esters from Datura wrightii Glandular Trichomes against Three Native Insect Herbivores
inferredcites →https://doi.org/10.1007/s10886-011-0012-7openalex-snapshot
Phaseoloidin, a Homogentisic Acid Glucoside from Nicotiana Attenuata Trichomes, Contributes to the Plant’s Resistance against Lepidopteran Herbivores
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Comparative structural profiling of trichome specialized metabolites in tomato (Solanum lycopersicum) and S. habrochaites: acylsugar profiles revealed by UHPLC/MS and NMR
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Studies of the site and mode of biosynthesis of tobacco trichome exudate components
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Inhibitory effect of sucrose ester of lauric acid on the growth of Escherichia coli
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Acylsugars of the wild tomato Lycopersicon pennellii in relation to geographic distribution of the species
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Analysis of sucrose esters – insecticides from the surface of tobacco plant leaves
inferredcites →https://doi.org/10.1016/j.funbio.2016.05.014openalex-snapshot
Maize leaf trichomes represent an entry point of infection for Fusarium species
inferredcites →https://doi.org/10.1016/s0031-9422(02)00608-8openalex-snapshot
Allometric analysis of the induced flavonols on the leaf surface of wild tobacco (Nicotiana attenuata)
inferredcites →https://doi.org/10.1016/s0031-9422(95)00522-6openalex-snapshot
Inhibition of tomato ringspot virus by flavonoids
inferredcites →https://doi.org/10.1016/s0065-2806(08)60230-1openalex-snapshot
The Consumption and Utilization of Food by Insects
inferredcites →https://doi.org/10.1016/s0305-1978(96)00100-7openalex-snapshot
Chemistry, toxicity and antifeedant activity of the resin of Flourensia thurifera
inferredcites →https://doi.org/10.1016/s0924-2244(00)00013-3openalex-snapshot
Practical Polyphenolics: From Structure to Molecular Recognition and Physiological Action
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Journal of Agricultural and Food Chemistry
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Characterization of the sucrose ester fraction from Nicotiana glutinosa
inferredcites →https://doi.org/10.1021/jf010200+openalex-snapshot
Rapid HPLC Screening of Jasmonate-Induced Increases in Tobacco Alkaloids, Phenolics, and Diterpene Glycosides in Nicotiana attenuata
inferredcites →https://doi.org/10.1021/jf1017737openalex-snapshot
Development and Validation of a Liquid Chromatography−Electrospray Ionization−Time-of-Flight Mass Spectrometry Method for Induced Changes in Nicotiana attenuata Leaves during Simulated Herbivory
inferredcites →https://doi.org/10.1021/jf960322fopenalex-snapshot
Characterization of Insecticidal Sugar Esters of Petunia
inferredcites →https://doi.org/10.1021/jf960748uopenalex-snapshot
Hydroxygeranyllinalool Glycosides from Tobacco Exhibit Antibiosis Activity in the Tobacco Budworm [Heliothis virescens (F.)]
inferredcites →https://doi.org/10.1023/a:1010341022761openalex-snapshot
Ontogeny Constrains Systemic Protease Inhibitor Response in Nicotiana attenuata
inferredcites →https://doi.org/10.1023/a:1020963817685openalex-snapshot
Biological Activity of Datura wrightii Glandular Trichome Exudate Against Manduca Sexta Larvae
inferredcites →https://doi.org/10.1038/nchembio.2007.5openalex-snapshot
The function of terpene natural products in the natural world
inferredcites →https://doi.org/10.1073/pnas.0904113106openalex-snapshot
Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate
inferredcites →https://doi.org/10.1073/pnas.1101306108openalex-snapshot
Trichome-derived O -acyl sugars are a first meal for caterpillars that tags them for predation
inferredcites →https://doi.org/10.1073/pnas.1207906109openalex-snapshot
Identification of a BAHD acetyltransferase that produces protective acyl sugars in tomato trichomes
inferredcites →https://doi.org/10.1073/pnas.1503106112openalex-snapshot
Navigating natural variation in herbivory-induced secondary metabolism in coyote tobacco populations using MS/MS structural analysis
inferredcites →https://doi.org/10.1073/pnas.1505765112openalex-snapshot
Native root-associated bacteria rescue a plant from a sudden-wilt disease that emerged during continuous cropping
inferredcites →https://doi.org/10.1073/pnas.1517930113openalex-snapshot
In vitro reconstruction and analysis of evolutionary variation of the tomato acylsucrose metabolic network
inferredcites →https://doi.org/10.1073/pnas.1610218113openalex-snapshot
Illuminating a plant’s tissue-specific metabolic diversity using computational metabolomics and information theory
inferredcites →https://doi.org/10.1073/pnas.95.14.8113openalex-snapshot
Jasmonate-induced responses are costly but benefit plants under attack in native populations
inferredcites →https://doi.org/10.1080/17550874.2012.754797openalex-snapshot
Transformational tools for next-generation plant ecology: manipulation of gene expression for the functional analysis of genes
inferredcites →https://doi.org/10.1093/aob/mch011openalex-snapshot
New Approaches for Studying and Exploiting an Old Protuberance, the Plant Trichome
inferredcites →https://doi.org/10.1093/jee/87.2.482openalex-snapshot
Acylglucoses from Wild Tomatoes Alter Behavior and Reduce Growth and Survival of Helicoverpa zea and Spodoptera exigua (Lepidoptera: Noctuidae)
inferredcites →https://doi.org/10.1093/jee/96.3.636openalex-snapshot
Structure-Function Relationships Affecting the Insecticidal and Miticidal Activity of Sugar Esters
inferredcites →https://doi.org/10.1093/jxb/erl155openalex-snapshot
Leaf hairs influence phytopathogenic fungus infection and confer an increased resistance when expressing a Trichoderma -1,3-glucanase
inferredcites →https://doi.org/10.1093/nar/gkv380openalex-snapshot
MetaboAnalyst 3.0—making metabolomics more meaningful
inferredcites →https://doi.org/10.1104/pp.010762openalex-snapshot
An Ecologically Motivated Analysis of Plant-Herbivore Interactions in Native Tobacco
inferredcites →https://doi.org/10.1104/pp.108.129510openalex-snapshot
Transcriptomic and Reverse Genetic Analysesof Branched-Chain Fatty Acid and Acyl Sugar Production inSolanum pennelliiandNicotiana benthamiana
inferredcites →https://doi.org/10.1104/pp.109.151738openalex-snapshot
R2R3-NaMYB8 Regulates the Accumulation of Phenylpropanoid-Polyamine Conjugates, Which Are Essential for Local and Systemic Defense against Insect Herbivores in Nicotiana attenuata
inferredcites →https://doi.org/10.1104/pp.112.204735openalex-snapshot
Striking Natural Diversity in Glandular Trichome Acylsugar Composition Is Shaped by Variation at the Acyltransferase2 Locus in the Wild Tomato Solanum habrochaites
inferredcites →https://doi.org/10.1104/pp.125.2.539openalex-snapshot
An Investigation of the Storage and Biosynthesis of Phenylpropenes in Sweet Basil
inferredcites →https://doi.org/10.1104/pp.15.00461openalex-snapshot
The Impact of the Branched-Chain Ketoacid Dehydrogenase Complex on Amino Acid Homeostasis in Arabidopsis
inferredcites →https://doi.org/10.1104/pp.15.01348openalex-snapshot
Acylsugar Acylhydrolases: Carboxylesterase-Catalyzed Hydrolysis of Acylsugars in Tomato Trichomes
inferredcites →https://doi.org/10.1104/pp.77.3.567openalex-snapshot
Epicuticular Lipid Accumulation on the Leaves of Lycopersicon pennellii (Corr.) D'Arcy and Lycopersicon esculentum Mill
inferredcites →https://doi.org/10.1104/pp.93.4.1544openalex-snapshot
Branched Chain Amino Acid Metabolism in the Biosynthesis of Lycopersicon pennellii Glucose Esters
inferredcites →https://doi.org/10.1105/tpc.104.029736openalex-snapshot
Metabolic, Genomic, and Biochemical Analyses of Glandular Trichomes from the Wild Tomato SpeciesLycopersicon hirsutumIdentify a Key Enzyme in the Biosynthesis of Methylketones
inferredcites →https://doi.org/10.1105/tpc.106.049353openalex-snapshot
Herbivory Rapidly Activates MAPK Signaling in Attacked and Unattacked Leaf Regions but Not between Leaves of Nicotiana attenuata
inferredcites →https://doi.org/10.1105/tpc.107.057885openalex-snapshot
A Novel Pathway for Sesquiterpene Biosynthesis fromZ,Z-Farnesyl Pyrophosphate in the Wild TomatoSolanum habrochaites
inferredcites →https://doi.org/10.1105/tpc.111.088229openalex-snapshot
Nicotiana attenuata LECTIN RECEPTOR KINASE1 Suppresses the Insect-Mediated Inhibition of Induced Defense Responses during Manduca sexta Herbivory
inferredcites →https://doi.org/10.1105/tpc.15.00087openalex-snapshot
Functionally Divergent Alleles and Duplicated Loci Encoding an Acyltransferase Contribute to Acylsugar Metabolite Diversity in Solanum Trichomes
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FITNESS COSTS OF CHEMICAL DEFENSE IN PLANTAGO LANCEOLATA L.: EFFECTS OF NUTRIENT AND COMPETITION STRESS
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Antimicrobial Activity of Sucrose Fatty Acid Ester Emulsifiers
inferredcites →https://doi.org/10.1111/j.1365-313x.2012.05040.xopenalex-snapshot
Evolution of TPS20‐related terpene synthases influences chemical diversity in the glandular trichomes of the wild tomato relative Solanum habrochaites
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BUTTERFLIES AND PLANTS: A STUDY IN COEVOLUTION
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Trichome‐borne and artificially applied acylsugars of wild tomato deter feeding and oviposition of the leafminer Liriomyza trifolii
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Proceedings of the National Academy of Sciences of the United States of America
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Efficient screening of transgenic plant lines for ecological research
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Explaining intraspecific diversity in plant secondary metabolites in an ecological context
inferredcites →https://doi.org/10.1111/pce.12416openalex-snapshot
Jasmonic acid signalling mediates resistance of the wild tobacco N icotiana attenuata to its native F usarium, but not A lternaria, fungal pathogens
inferredcites →https://doi.org/10.1186/1472-6785-4-12openalex-snapshot
ISSR and AFLP analysis of the temporal and spatial population structure of the post-fire annual, Nicotiana attenuata, in SW Utah
inferredcites →https://doi.org/10.1186/s12864-016-3465-9openalex-snapshot
Nicotiana attenuata Data Hub (NaDH): an integrative platform for exploring genomic, transcriptomic and metabolomic data in wild tobacco
inferredcites →https://doi.org/10.1186/s13007-016-0130-xopenalex-snapshot
High-throughput quantification of more than 100 primary- and secondary-metabolites, and phytohormones by a single solid-phase extraction based sample preparation with analysis by UHPLC–HESI–MS/MS
inferredcites →https://doi.org/10.1271/bbb.57.1355openalex-snapshot
Antibiotic Activities of Sugar Esters Isolated from SelectedNicotianaSpecies
inferredcites →https://doi.org/10.1371/journal.pone.0102915openalex-snapshot
Isolating Fungal Pathogens from a Dynamic Disease Outbreak in a Native Plant Population to Establish Plant-Pathogen Bioassays for the Ecological Model Plant Nicotiana attenuata
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Alternaria diseases of citrus - Novel pathosystems.
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Sex-specific odorant receptors of the tobacco hornworm Manduca sexta
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Plant Glandular Trichomes as Targets for Breeding or Engineering of Resistance to Herbivores

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Lipid metabolites profiles and allene oxide cyclase (AOC) expression pattern in Houttuynia cordata from diverse geographical regions: Unraveling the response to temperature variations
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Involvement of isopropylmalate dehydratase in chloroplast development and acylsugar accumulation in tobacco
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ASTF1, an AP2/ERF-family transcription factor and ortholog of cultivated tomato LEAFLESS, is required for acylsugar biosynthesis
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The oomycete MAMP, arachidonic acid, and an Ascophyllum nodosum -derived plant biostimulant induce defense metabolome remodeling in tomato
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Heat stress induces a developmental shift from type-V to type-IV trichome dependent on jasmonate signaling in tomato
inferred← citeshttps://doi.org/10.1101/2023.10.06.561305openalex-snapshot
Woolly mutation with Get02 locus overcomes the polygenic nature of trichome-based pest resistance in tomato
inferred← citeshttps://doi.org/10.1101/2024.02.26.582111openalex-snapshot
Knockout mutations of Nicotiana benthamiana defenses reveal the relative importance of acylsugars, nicotine, and a serine protease inhibitor in a natural setting
inferred← citeshttps://doi.org/10.1101/2024.06.03.597112openalex-snapshot
QTL mapping in field plant populations reveals a genetic basis for frequency- and spatially-specific fungal pathosystem resistance
inferred← citeshttps://doi.org/10.1101/2025.02.17.638719openalex-snapshot
A Metabolic Complex Involved in Tomato Specialized Metabolism
inferred← citeshttps://doi.org/10.1101/2025.07.16.665232openalex-snapshot
Novel production of structurally diverse and sticky defense metabolites on wild tomatillo fruits
inferred← citeshttps://doi.org/10.1104/pp.17.00538openalex-snapshot
Characterization of Trichome-Expressed BAHD Acyltransferases in Petunia axillaris Reveals Distinct Acylsugar Assembly Mechanisms within the Solanaceae
inferred← citeshttps://doi.org/10.1104/pp.17.00727openalex-snapshot
Plant Glandular Trichomes: Natural Cell Factories of High Biotechnological Interest
inferred← citeshttps://doi.org/10.1104/pp.20.00171openalex-snapshot
Argonaute4 Modulates Resistance to Fusariumbrachygibbosum Infection by Regulating Jasmonic Acid Signaling
inferred← citeshttps://doi.org/10.1104/pp.20.00276openalex-snapshot
Specialized Metabolism in a Nonmodel Nightshade: Trichome Acylinositol Biosynthesis
inferred← citeshttps://doi.org/10.1105/tpc.19.00552openalex-snapshot
Candidate Gene Networks for Acylsugar Metabolism and Plant Defense in Wild Tomato Solanum pennellii
inferred← citeshttps://doi.org/10.1111/jipb.70225openalex-snapshot
Metabolite‐mediated plant immunity: From traditional defenders to artificial elicitors
inferred← citeshttps://doi.org/10.1111/nph.18026openalex-snapshot
CsMYB1 integrates the regulation of trichome development and catechins biosynthesis in tea plant domestication
inferred← citeshttps://doi.org/10.1111/nph.18732openalex-snapshot
Exploring the metabolic basis of growth/defense trade‐offs in complex environments with Nicotiana attenuata plants cosilenced in NaMYC2a/b expression
inferred← citeshttps://doi.org/10.1111/nph.19068openalex-snapshot
A glimmer of hope – ash genotypes with increased resistance to ash dieback pathogen show cross‐resistance to emerald ash borer
inferred← citeshttps://doi.org/10.1111/nph.70198openalex-snapshot
Role of LEAFLESS , an AP2 / ERF family transcription factor, in the regulation of trichome specialized metabolism
inferred← citeshttps://doi.org/10.1111/pce.15135openalex-snapshot
Metabolic and Molecular Insights Into Nicotiana benthamiana Trichome Exudates: An Ammunition Depot for Plant Resistance Against Insect Pests
inferred← citeshttps://doi.org/10.1111/pce.15195openalex-snapshot
Acylsugars, Nicotine and a Protease Inhibitor Provide Variable Protection for Nicotiana benthamiana in a Natural Setting
inferred← citeshttps://doi.org/10.1111/pce.70690openalex-snapshot
Earthworms Enhance Maize Resistance to Aphids From Bottom to Top via Increasing Soil Bacillus Abundance
inferred← citeshttps://doi.org/10.1111/pce.70817openalex-snapshot
Sugars as Central Integrators of Plant Immunity and Stress Responses
inferred← citeshttps://doi.org/10.1111/tpj.13773openalex-snapshot
Plant–arthropod interactions: who is the winner?
inferred← citeshttps://doi.org/10.1111/tpj.14331openalex-snapshot
Using natural variation to achieve a whole‐plant functional understanding of the responses mediated by jasmonate signaling
inferred← citeshttps://doi.org/10.1111/tpj.16370openalex-snapshot
Altered methionine metabolism impacts phenylpropanoid production and plant development in Arabidopsis thaliana
inferred← citeshttps://doi.org/10.1126/sciadv.aaw3754openalex-snapshot
Evolution of metabolic novelty: A trichome-expressed invertase creates specialized metabolic diversity in wild tomato
inferred← citeshttps://doi.org/10.1126/sciadv.abj8726openalex-snapshot
It happened again: Convergent evolution of acylglucose specialized metabolism in black nightshade and wild tomato
inferred← citeshttps://doi.org/10.1126/sciadv.adn3991openalex-snapshot
Tomato root specialized metabolites evolved through gene duplication and regulatory divergence within a biosynthetic gene cluster
inferred← citeshttps://doi.org/10.1146/annurev-arplant-062922-050122openalex-snapshot
BAHD Company: The Ever-Expanding Roles of the BAHD Acyltransferase Gene Family in Plants
inferred← citeshttps://doi.org/10.15376/biores.17.2.3025-3041openalex-snapshot
Application of synthetic acyl glucopyranosides for white-rot and brown-rot fungal decay resistance in aspen and pine wood
inferred← citeshttps://doi.org/10.1590/1678-4499.20210022openalex-snapshot
Acylsugars in tomato varieties confer resistance to the whitefly and reduce the spread of fumagine
inferred← citeshttps://doi.org/10.1590/1807-1929/agriambi.v24n9p596-602openalex-snapshot
Productivity, acylsugar concentrations and resistance to the two-spotted spider mite in genotypes of salad tomatoes
inferred← citeshttps://doi.org/10.3389/fpls.2022.993279openalex-snapshot
Acylsugar protection of Nicotiana benthamiana confers mortality and transgenerational fitness costs in Spodoptera litura
inferred← citeshttps://doi.org/10.3390/agronomy12010002openalex-snapshot
Vertical Farming: The Only Way Is Up?
inferred← citeshttps://doi.org/10.3390/horticulturae9080868openalex-snapshot
Comparative Transcriptome Analyses Reveal Different Regulatory Mechanisms in Ecological Adaptation between Chrysanthemum vestitum and Chrysanthemum mongolicum
inferred← citeshttps://doi.org/10.3390/ijms24065207openalex-snapshot
Genome-Wide Investigation and Functional Analysis Reveal That CsGeBP4 Is Required for Tea Plant Trichome Formation
inferred← citeshttps://doi.org/10.3390/metabo10100401openalex-snapshot
An Integrated Analytical Approach Reveals Trichome Acylsugar Metabolite Diversity in the Wild Tomato Solanum pennellii
inferred← citeshttps://doi.org/10.3390/molecules27123728openalex-snapshot
Pennelliiside D, a New Acyl Glucose from Solanum pennellii and Chemical Synthesis of Pennelliisides
inferred← citeshttps://doi.org/10.3390/pathogens12111275openalex-snapshot
Plant-Disease-Suppressive and Growth-Promoting Activities of Endophytic and Rhizobacterial Isolates Associated with Citrullus colocynthis
inferred← citeshttps://doi.org/10.3390/plants11101309openalex-snapshot
The Genetic Complexity of Type-IV Trichome Development Reveals the Steps towards an Insect-Resistant Tomato
inferred← citeshttps://doi.org/10.3724/sp.j.1006.2025.44188openalex-snapshot
Morphological characteristics, types, and developmental process of potato leaf trichomes
inferred← citeshttps://doi.org/10.48130/vr-2023-0024openalex-snapshot
Advances in the regulatory mechanisms of multicellular trichome formation and its secondary metabolite synthesis in vegetable crops
inferred← citeshttps://doi.org/10.70675/63486756z3916z4dd6z9701z5a91575bbd5eopenalex-snapshot
Metabolomics-centered exploration of plant specialized metabolism innovations : a case-study on the chemodiversity, biosynthesis and anti-herbivory functions of N-acylnornicotines in the genus Nicotiana
inferred← citeshttps://doi.org/10.7554/elife.28468openalex-snapshot
Evolutionary routes to biochemical innovation revealed by integrative analysis of a plant-defense related specialized metabolic pathway
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