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Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/jcp.24457openalex-snapshot
Measurement of ATP in Single Oocytes: Impact of Maturation and Cumulus Cells on Levels and Consumption
inferredcites →https://doi.org/10.1006/dbio.1999.9209openalex-snapshot
Z/AP, a Double Reporter for Cre-Mediated Recombination
inferredcites →https://doi.org/10.1007/bf02535072openalex-snapshot
Age‐related changes in the lipid compositions of rat and human tissues
inferredcites →https://doi.org/10.1007/s00404-011-2169-2openalex-snapshot
Coenzyme Q10 content in follicular fluid and its relationship with oocyte fertilization and embryo grading
inferredcites →https://doi.org/10.1007/s10815-011-9588-7openalex-snapshot
The contribution of mitochondrial function to reproductive aging
inferredcites →https://doi.org/10.1016/j.cccn.2004.04.003openalex-snapshot
Age-related changes in plasma coenzyme Q10 concentrations and redox state in apparently healthy children and adults
inferredcites →https://doi.org/10.1016/j.mad.2012.12.001openalex-snapshot
Ceramide and its transport protein (CERT) contribute to deterioration of mitochondrial structure and function in aging oocytes
inferredcites →https://doi.org/10.1016/j.mito.2007.03.007openalex-snapshot
Endogenous synthesis of coenzyme Q in eukaryotes
inferredcites →https://doi.org/10.1016/j.mito.2011.09.011openalex-snapshot
Parkinson's disease-like neuromuscular defects occur in prenyl diphosphate synthase subunit 2 (Pdss2) mutant mice
inferredcites →https://doi.org/10.1016/j.nbd.2011.08.006openalex-snapshot
Cerebellar defects in Pdss2 conditional knockout mice during embryonic development and in adulthood
inferredcites →https://doi.org/10.1016/j.ydbio.2008.01.048openalex-snapshot
Age-associated increase in aneuploidy and changes in gene expression in mouse eggs
inferredcites →https://doi.org/10.1016/s0303-7207(99)00238-5openalex-snapshot
Follicle dynamics during ovarian ageing
inferredcites →https://doi.org/10.1016/s0378-5122(98)00068-1openalex-snapshot
Declining fecundity and ovarian ageing in natural fertility populations
inferredcites →https://doi.org/10.1016/s0960-9822(06)00059-5openalex-snapshot
Zp3–cre, a transgenic mouse line for the activation or inactivation of loxP-flanked target genes specifically in the female germ line
inferredcites →https://doi.org/10.1023/a:1027301405614openalex-snapshot
An aging-related cell surface NADH oxidase (arNOX) generates superoxide and is inhibited by coenzyme Q
inferredcites →https://doi.org/10.1080/07315724.2001.10719063openalex-snapshot
Biochemical Functions of Coenzyme Q 10
inferredcites →https://doi.org/10.1086/510023openalex-snapshot
Leigh Syndrome with Nephropathy and CoQ10 Deficiency Due to decaprenyl diphosphate synthase subunit 2 (PDSS2) Mutations
inferredcites →https://doi.org/10.1093/hmg/ddh241openalex-snapshot
Age-associated alteration of gene expression patterns in mouse oocytes
inferredcites →https://doi.org/10.1093/hmg/dds530openalex-snapshot
Dysfunctional Coq9 protein causes predominant encephalomyopathy associated with CoQ deficiency
inferredcites →https://doi.org/10.1093/humrep/16.5.909openalex-snapshot
Mitochondrial aggregation patterns and activity in human oocytes and preimplantation embryos
inferredcites →https://doi.org/10.1093/humrep/17.10.2678openalex-snapshot
Ageing-associated aberration in meiosis of oocytes from senescence-accelerated mice
inferredcites →https://doi.org/10.1093/humupd/8.2.141openalex-snapshot
The variability of female reproductive ageing
inferredcites →https://doi.org/10.1093/oxfordjournals.humrep.a019080openalex-snapshot
Fertilization and early embryology: Influence of maternal age on meiotic spindle assembly oocytes from naturally cycling women
inferredcites →https://doi.org/10.1093/oxfordjournals.humrep.a135954openalex-snapshot
Fertilization and early embryolgoy: ATP content of human oocytes and developmental potential and outcome after in-vitro fertilization and embryo transfer
inferredcites →https://doi.org/10.1095/biolreprod.104.032391openalex-snapshot
Effect of Treating Induced Mitochondrial Damage on Embryonic Development and Epigenesis
inferredcites →https://doi.org/10.1095/biolreprod.105.048611openalex-snapshot
Developmental Effects of Sublethal Mitochondrial Injury in Mouse Oocytes1
inferredcites →https://doi.org/10.1095/biolreprod.111.093583openalex-snapshot
NLRP5 Mediates Mitochondrial Function in Mouse Oocytes and Embryos1
inferredcites →https://doi.org/10.1095/biolreprod.111.094094openalex-snapshot
Age-Dependent Susceptibility of Chromosome Cohesion to Premature Separase Activation in Mouse Oocytes1
inferredcites →https://doi.org/10.1096/fj.09-152728openalex-snapshot
Reactive oxygen species, oxidative stress, and cell death correlate with level of CoQ 10 deficiency
inferredcites →https://doi.org/10.1111/j.1742-4658.2010.07554.xopenalex-snapshot
Developmental consequences of alternative Bcl‐x splicing during preimplantation embryo development
inferredcites →https://doi.org/10.1126/scitranslmed.3004925openalex-snapshot
Impairment of BRCA1-Related DNA Double-Strand Break Repair Leads to Ovarian Aging in Mice and Humans
inferredcites →https://doi.org/10.1152/ajpendo.00046.2002openalex-snapshot
Metabolic changes in the glucose-induced apoptotic blastocyst suggest alterations in mitochondrial physiology
inferredcites →https://doi.org/10.1152/ajprenal.90445.2008openalex-snapshot
Coenzyme Q10 supplementation rescues renal disease in Pdss2kd/kd mice with mutations in prenyl diphosphate synthase subunit 2
inferredcites →https://doi.org/10.1159/000264313openalex-snapshot
Coenzyme Q10 in Pregnancy
inferredcites →https://doi.org/10.1172/jci45693openalex-snapshot
COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness
inferredcites →https://doi.org/10.1210/en.2007-1273openalex-snapshot
One-Cell Zygote Transfer from Diabetic to Nondiabetic Mouse Results in Congenital Malformations and Growth Retardation in Offspring
inferredcites →https://doi.org/10.1210/me.2009-0033openalex-snapshot
Maternal Diabetes Causes Mitochondrial Dysfunction and Meiotic Defects in Murine Oocytes
inferredcites →https://doi.org/10.1242/dev.02744openalex-snapshot
Regulation of redox metabolism in the mouse oocyte and embryo
inferredcites →https://doi.org/10.1371/journal.pgen.1000061openalex-snapshot
Primary Coenzyme Q Deficiency in Pdss2 Mutant Mice Causes Isolated Renal Disease
inferredcites →https://doi.org/10.1371/journal.pone.0049217openalex-snapshot
High Fat Diet Induced Developmental Defects in the Mouse: Oocyte Meiotic Aneuploidy and Fetal Growth Retardation/Brain Defects
inferredcites →https://doi.org/10.1530/jrf.0.0720009openalex-snapshot
Pyruvate and glucose uptake by mouse ova and preimplantation embryos
inferredcites →https://doi.org/10.1677/joe.0.0960023openalex-snapshot
Ovarian follicle dynamics in mice: a comparative study of three inbred strains and an F1 hybrid
inferredcites →https://doi.org/10.3109/10409238.2012.741564openalex-snapshot
Molecular genetics of ubiquinone biosynthesis in animals

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Mitochondrial DNA Quantification Correlates with the Developmental Potential of Human Euploid Blastocysts but not with that of Mosaic Blastocysts
inferred← citeshttps://doi.org/10.1002/advs.202409740openalex-snapshot
Bacteroides Fragilis Transplantation Reverses Reproductive Senescence by Transporting Extracellular Vesicles Through the Gut‐Ovary Axis
inferred← citeshttps://doi.org/10.1002/advs.202510226openalex-snapshot
Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling
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The role of mitochondria in the female germline: Implications to fertility and inheritance of mitochondrial diseases
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An Application of NGS for Molecular Investigations in Perrault Syndrome: Study of 14 Families and Review of the Literature
inferred← citeshttps://doi.org/10.1002/jbt.22398openalex-snapshot
Upregulation of FSHR and PCNA by administration of coenzyme Q10 on cyclophosphamide‐induced premature ovarian failure in a mouse model
inferred← citeshttps://doi.org/10.1002/jcp.30468openalex-snapshot
Oxidative stress in oocyte aging and female reproduction
inferred← citeshttps://doi.org/10.1002/mco2.70481openalex-snapshot
Ovarian Aging: Mechanisms, Age‐Related Disorders, and Therapeutic Interventions
inferred← citeshttps://doi.org/10.1002/mnfr.202200363openalex-snapshot
Protocatechuic Acid Delays Postovulatory Oocyte Ageing in Mouse
inferred← citeshttps://doi.org/10.1002/mrd.23129openalex-snapshot
Mitochondrial transfer from aged adipose‐derived stem cells does not improve the quality of aged oocytes in C57BL/6 mice
inferred← citeshttps://doi.org/10.1002/rmb2.12245openalex-snapshot
Updating the markers for oocyte quality evaluation: intracellular temperature as a new index
inferred← citeshttps://doi.org/10.1002/rmb2.70086openalex-snapshot
Mitochondrial‐Targeted Phytochemicals in Reproductive Aging: Mechanisms and Translational Potential
inferred← citeshttps://doi.org/10.1002/wsbm.1613openalex-snapshot
Aging and oocyte competence: A molecular cell perspective
inferred← citeshttps://doi.org/10.1007/5584_2019_456openalex-snapshot
Oocyte Aging: The Role of Cellular and Environmental Factors and Impact on Female Fertility
inferred← citeshttps://doi.org/10.1007/978-3-030-12668-1_5openalex-snapshot
Targeting Mitochondrial Defects to Increase Longevity in Animal Models of Neurodegenerative Diseases
inferred← citeshttps://doi.org/10.1007/978-3-030-23235-1_2openalex-snapshot
Ovarian and Hypothalamic Aging
inferred← citeshttps://doi.org/10.1007/978-3-030-45642-9_1openalex-snapshot
The Current Coenzyme Q Science and Knowledge
inferred← citeshttps://doi.org/10.1007/978-3-030-45642-9_14openalex-snapshot
Coenzyme Q10 in Fertility and Reproduction
inferred← citeshttps://doi.org/10.1007/978-3-031-71674-4_16openalex-snapshot
Bioprospecting Nutraceuticals for Human Welfare
inferred← citeshttps://doi.org/10.1007/978-3-031-77255-9_14openalex-snapshot
The Management of IVF Patients with Diminished Ovarian Reserve
inferred← citeshttps://doi.org/10.1007/978-3-319-41749-3_4openalex-snapshot
Coenzyme Q10 in Male Infertility
inferred← citeshttps://doi.org/10.1007/978-3-319-60855-6_2openalex-snapshot
Control of Mammalian Oocyte Development by Interactions with the Maternal Follicular Environment
inferred← citeshttps://doi.org/10.1007/978-3-662-55601-6_47-1openalex-snapshot
Adjuvante Therapien in der Reproduktionsmedizin
inferred← citeshttps://doi.org/10.1007/978-3-662-57636-6_47openalex-snapshot
Adjuvante Therapien in der Reproduktionsmedizin
inferred← citeshttps://doi.org/10.1007/978-981-19-8848-6_7openalex-snapshot
Prevention and Management of Ovarian Aging
inferred← citeshttps://doi.org/10.1007/978-981-19-8848-6_9openalex-snapshot
Strategies to Maintain Ovarian Function
inferred← citeshttps://doi.org/10.1007/s00018-022-04288-0openalex-snapshot
Impaired primordial follicle assembly in offspring ovaries from zearalenone-exposed mothers involves reduced mitochondrial activity and altered epigenetics in oocytes
inferred← citeshttps://doi.org/10.1007/s10735-025-10566-5openalex-snapshot
Coenzyme Q10 may protect ovarian tissue against by the nearly century-old drug methotrexate caused gonadotoxicity: a biochemical, flow cytometric, and histopathological study
inferred← citeshttps://doi.org/10.1007/s10815-016-0751-zopenalex-snapshot
Can Coenzyme Q10 supplementation protect the ovarian reserve against oxidative damage?
inferred← citeshttps://doi.org/10.1007/s10815-017-0882-xopenalex-snapshot
The association between coenzyme Q10 concentrations in follicular fluid with embryo morphokinetics and pregnancy rate in assisted reproductive techniques
inferred← citeshttps://doi.org/10.1007/s10815-017-1027-yopenalex-snapshot
CoQ10 increases mitochondrial mass and polarization, ATP and Oct4 potency levels, and bovine oocyte MII during IVM while decreasing AMPK activity and oocyte death
inferred← citeshttps://doi.org/10.1007/s10815-018-1213-6openalex-snapshot
Why AMPK agonists not known to be stressors may surprisingly contribute to miscarriage or hinder IVF/ART
inferred← citeshttps://doi.org/10.1007/s10815-018-1327-xopenalex-snapshot
Can peri-ovulatory putrescine supplementation improve egg quality in older infertile women?
inferred← citeshttps://doi.org/10.1007/s10815-019-01523-9openalex-snapshot
HDL functionality in follicular fluid in normal-weight and obese women undergoing assisted reproductive treatment
inferred← citeshttps://doi.org/10.1007/s10815-020-01959-4openalex-snapshot
Molecular basis of reproductive senescence: insights from model organisms
inferred← citeshttps://doi.org/10.1007/s10815-020-02045-5openalex-snapshot
Suboptimal trophectoderm mitochondrial DNA level is associated with delayed blastocyst development
inferred← citeshttps://doi.org/10.1007/s10815-024-03052-6openalex-snapshot
The role of CoQ10 in embryonic development
inferred← citeshttps://doi.org/10.1007/s10815-025-03625-zopenalex-snapshot
Investigating perceptions and usage of fertility supplements: a mixed methods analysis of a large online forum
inferred← citeshttps://doi.org/10.1007/s11033-026-12714-wopenalex-snapshot
Oocyte quality in endometriosis-associated infertility: a narrative analysis of mechanisms and therapeutic options
inferred← citeshttps://doi.org/10.1007/s11356-022-24920-7openalex-snapshot
The antioxidant effects of coenzyme Q10 on albino rat testicular toxicity and apoptosis triggered by bisphenol A
inferred← citeshttps://doi.org/10.1007/s11357-026-02243-6openalex-snapshot
Oocyte aging in focus: Environmental and endogenous stressors driving reproductive potential decline
inferred← citeshttps://doi.org/10.1007/s11427-025-3284-8openalex-snapshot
Reprogramming senescent granulosa cells for germ-cell generation
inferred← citeshttps://doi.org/10.1007/s12011-020-02192-xopenalex-snapshot
Impact of Dietary Selenium on Modulation of Expression of Several Non-Selenoprotein Genes Related to Key Ovarian Functions, Female Fertility, and Proteostasis: a Transcriptome-Based Analysis of the Aging Mice Ovaries
inferred← citeshttps://doi.org/10.1007/s12020-016-1068-5openalex-snapshot
How FSH and AMH reflect probabilities of oocyte numbers in poor prognosis patients with small oocyte yields
inferred← citeshttps://doi.org/10.1007/s12020-017-1498-8openalex-snapshot
Suspected ontogeny of a recently described hypo-androgenic PCOS-like phenotype with advancing age
inferred← citeshttps://doi.org/10.1007/s42399-025-01976-3openalex-snapshot
Pharmacotherapeutic Role of Ketohexokinase in Metabolic Disorders and PCOS: A Systematic Review
inferred← citeshttps://doi.org/10.1007/s43032-021-00523-4openalex-snapshot
Mitochondria: emerging therapeutic strategies for oocyte rescue
inferred← citeshttps://doi.org/10.1007/s43032-022-01136-1openalex-snapshot
Association of Coenzyme Q10 with Premature Ovarian Insufficiency
inferred← citeshttps://doi.org/10.1007/s43032-024-01606-8openalex-snapshot
The Reproductive Lifespan of Ovarian Follicle
inferred← citeshttps://doi.org/10.1007/s43032-025-01811-zopenalex-snapshot
The Mechanistic Study of Mitochondrial Autophagy and Ferroptosis in the Progression of Decreased Ovarian Reserve
inferred← citeshttps://doi.org/10.1007/s43032-026-02113-8openalex-snapshot
Mitochondrial Function and Dysfunction in Female Fertility: Biological Mechanisms, Genetic Determinants, and Therapeutic Opportunities – A Review
inferred← citeshttps://doi.org/10.1016/b978-0-12-811353-0.00009-9openalex-snapshot
Female Reproductive Aging
inferred← citeshttps://doi.org/10.1016/b978-0-12-813209-8.00021-2openalex-snapshot
The Role of Mitochondria in Reproductive Function and Assisted Reproduction
inferred← citeshttps://doi.org/10.1016/b978-0-12-818698-5.00018-3openalex-snapshot
Coenzyme Q10 supplementation in aging
inferred← citeshttps://doi.org/10.1016/b978-0-12-819096-8.00023-9openalex-snapshot
Coenzyme Q: An endogenous antioxidant
inferred← citeshttps://doi.org/10.1016/b978-0-12-823344-3.00002-9openalex-snapshot
Ovarian Reserve and Early Follicle Development: Prerequisite Knowledge for Understanding Ovarian Tissue Harvesting for Cryopreservation
inferred← citeshttps://doi.org/10.1016/b978-0-323-85687-4.00001-4openalex-snapshot
Nutritional supplements and other adjuvants in fertility care
inferred← citeshttps://doi.org/10.1016/b978-0-443-13492-0.00005-0openalex-snapshot
Implications for policy
inferred← citeshttps://doi.org/10.1016/b978-0-443-13492-0.00027-xopenalex-snapshot
Geospatiotemporal and causal inferential epidemiological survey and exploration of cannabinoid- and substance-related carcinogenesis in USA 2003–2017
inferred← citeshttps://doi.org/10.1016/b978-0-443-18858-9.00003-2openalex-snapshot
Mitochondrial dynamics and mitochondrial biogenesis
inferred← citeshttps://doi.org/10.1016/b978-0-443-21477-6.00282-0openalex-snapshot
Evaluation and ART of the Low Ovarian Responder Patient
inferred← citeshttps://doi.org/10.1016/bs.vh.2022.10.004openalex-snapshot
Beneficial antioxidant effects of Coenzyme Q10 on reproduction
inferred← citeshttps://doi.org/10.1016/j.anireprosci.2019.106256openalex-snapshot
Beneficial effects of dietary coenzyme Q10 on the productive and reproductive variables of broiler breeder hens
inferred← citeshttps://doi.org/10.1016/j.anireprosci.2025.107856openalex-snapshot
Mitoquinone mesylate promotes oocyte maturation and subsequent embryonic development by regulating oxidative stress in Tibetan sheep
inferred← citeshttps://doi.org/10.1016/j.anireprosci.2026.108307openalex-snapshot
Mineral-driven molecular signatures of energy metabolism underpin sperm motility in buffalo
inferred← citeshttps://doi.org/10.1016/j.aohep.2019.03.007openalex-snapshot
HIF1a Inhibitor Rescues Acute-on-Chronic Liver Failure
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Mitochondrial quality control dysfunction in osteoarthritis: Mechanisms, therapeutic strategies & future prospects
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Mitochondria in Ovarian Aging and Reproductive Longevity
inferred← citeshttps://doi.org/10.1016/j.arr.2021.101345openalex-snapshot
Redox imbalance in age-related ovarian dysfunction and perspectives for its prevention
inferred← citeshttps://doi.org/10.1016/j.arr.2021.101378openalex-snapshot
Mitochondria: Their relevance during oocyte ageing
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Applying a systems approach to thyroid physiology: Looking at the whole with a mitochondrial perspective instead of judging single TSH values or why we should know more about mitochondria to understand metabolism
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Pharmacologic interventions targeting ovarian aging, cancer, and mitochondrial dysfunction: An updated evidence
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Pharmacology of medications used for ovarian stimulation
inferred← citeshttps://doi.org/10.1016/j.bioactmat.2022.10.019openalex-snapshot
Delivery of coenzyme Q10 loaded micelle targets mitochondrial ROS and enhances efficiency of mesenchymal stem cell therapy in intervertebral disc degeneration
inferred← citeshttps://doi.org/10.1016/j.cbpa.2022.111152openalex-snapshot
C. elegans as a model organism to study female reproductive health
inferred← citeshttps://doi.org/10.1016/j.celrep.2020.107987openalex-snapshot
Nicotinamide Mononucleotide Supplementation Reverses the Declining Quality of Maternally Aged Oocytes
inferred← citeshttps://doi.org/10.1016/j.ebiom.2019.02.020openalex-snapshot
Fibroblast growth factor 21 coordinates adiponectin to mediate the beneficial effects of low-protein diet on primordial follicle reserve
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2024.116679openalex-snapshot
Impact of DEHP on mitochondria-associated endoplasmic reticulum membranes and reproductive toxicity in ovary
inferred← citeshttps://doi.org/10.1016/j.ejogrb.2026.115193openalex-snapshot
Resveratrol supplementation and assisted reproduction outcomes: A systematic review and meta-analysis
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Itaconate prolongs the healthy lifespan by activating UPRmt in Caenorhabditis elegans
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Live-birth rates in very poor prognosis patients, who are defined as poor responders under the Bologna criteria, with nonelective single embryo, two-embryo, and three or more embryos transferred
inferred← citeshttps://doi.org/10.1016/j.fertnstert.2016.01.013openalex-snapshot
Aging and the environment affect gamete and embryo potential: can we intervene?
inferred← citeshttps://doi.org/10.1016/j.fertnstert.2018.10.036openalex-snapshot
Mitochondria as a tool for oocyte rejuvenation
inferred← citeshttps://doi.org/10.1016/j.fertnstert.2020.04.002openalex-snapshot
Coenzyme Q10 supplementation of human oocyte in vitro maturation reduces postmeiotic aneuploidies
inferred← citeshttps://doi.org/10.1016/j.fertnstert.2020.05.009openalex-snapshot
A battery boost for old eggs?
inferred← citeshttps://doi.org/10.1016/j.fertnstert.2022.01.029openalex-snapshot
Pretreatment: Does it improve quantity or quality?
inferred← citeshttps://doi.org/10.1016/j.fertnstert.2026.04.002openalex-snapshot
Optimization of conception with intercourse for women with infertility
inferred← citeshttps://doi.org/10.1016/j.fertnstert.2026.05.149openalex-snapshot
Can a focus on intracellular signaling assist us with ovarian stimulation in poor-prognosis patients?
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2019.08.002openalex-snapshot
Coenzyme Q10 ameliorates the quality of postovulatory aged oocytes by suppressing DNA damage and apoptosis
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2026.05.333openalex-snapshot
Bushen Tiaojing decoction ameliorates meiotic impairment to improve oocyte quality during aging through blocking the iron overload-induced p53/CDK1/ESPL1 pathway
inferred← citeshttps://doi.org/10.1016/j.genrep.2025.102240openalex-snapshot
SURF1 p.D202H variant is not associated with Leigh syndrome but may contribute to impaired pregnancy outcomes
inferred← citeshttps://doi.org/10.1016/j.gyobfe.2015.10.008openalex-snapshot
Fertilité et insuffisance ovarienne : de nouveaux traitements en perspective ?
inferred← citeshttps://doi.org/10.1016/j.intimp.2025.115529openalex-snapshot
Mitochondrial targeting of coenzyme Q10 in inflammatory bowel disease: mechanisms, challenges, and prospects for clinical application
inferred← citeshttps://doi.org/10.1016/j.isci.2024.110293openalex-snapshot
Type III adenylyl cyclase is essential for follicular development in female mice and their reproductive lifespan
inferred← citeshttps://doi.org/10.1016/j.isci.2026.114733openalex-snapshot
Metabolic, epigenetic, and immune crosstalk in ovarian aging
inferred← citeshttps://doi.org/10.1016/j.jare.2023.11.033openalex-snapshot
New insights on mitochondrial heteroplasmy observed in ovarian diseases
inferred← citeshttps://doi.org/10.1016/j.jep.2023.116424openalex-snapshot
Comparing steamed and wine-stewed Rehmanniae Radix in terms of Yin-nourishing effects via metabolomics and microbiome analysis
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Zuogui pills ameliorate chemotherapy-induced ovarian aging by improving stemness, regulating cell cycle and reducing apoptosis of oogonial stem cells via the Notch1/Nrf2 pathway
inferred← citeshttps://doi.org/10.1016/j.jes.2025.09.049openalex-snapshot
Maternal exposure to N, N-dimethylformamide impairs primordial follicle assembly, follicular development, and oocyte maturation in female offspring
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Reproductive aging: biological pathways and potential interventive strategies
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Long-term treatment of Nicotinamide mononucleotide improved age-related diminished ovary reserve through enhancing the mitophagy level of granulosa cells in mice
inferred← citeshttps://doi.org/10.1016/j.jri.2024.104277openalex-snapshot
Impact of repeated ovarian hyperstimulation on the reproductive function
inferred← citeshttps://doi.org/10.1016/j.jsbmb.2016.12.004openalex-snapshot
New PCOS-like phenotype in older infertile women of likely autoimmune adrenal etiology with high AMH but low androgens
inferred← citeshttps://doi.org/10.1016/j.mad.2024.111913openalex-snapshot
The close relationship between oocyte aging and telomere shortening, and possible interventions for telomere protection
inferred← citeshttps://doi.org/10.1016/j.mce.2020.111073openalex-snapshot
Melatonin alleviates the deterioration of oocytes and hormonal disorders from mice subjected to glyphosate
inferred← citeshttps://doi.org/10.1016/j.mehy.2018.04.011openalex-snapshot
Pathways from epigenomics and glycobiology towards novel biomarkers of addiction and its radical cure
inferred← citeshttps://doi.org/10.1016/j.mito.2024.101845openalex-snapshot
Research progress on mitochondrial damage and repairing in oocytes: A review
inferred← citeshttps://doi.org/10.1016/j.mito.2024.101946openalex-snapshot
PKD regulates mitophagy to prevent oxidative stress and mitochondrial dysfunction during mouse oocyte maturation
inferred← citeshttps://doi.org/10.1016/j.molmed.2018.01.008openalex-snapshot
Untapped Reserves: Controlling Primordial Follicle Growth Activation
inferred← citeshttps://doi.org/10.1016/j.mrfmmm.2016.05.002openalex-snapshot
Chromothripsis and epigenomics complete causality criteria for cannabis- and addiction-connected carcinogenicity, congenital toxicity and heritable genotoxicity
inferred← citeshttps://doi.org/10.1016/j.mrrev.2020.108320openalex-snapshot
Mechanisms of oocyte aneuploidy associated with advanced maternal age
inferred← citeshttps://doi.org/10.1016/j.ogc.2018.07.001openalex-snapshot
Declining Fertility with Reproductive Aging
inferred← citeshttps://doi.org/10.1016/j.phymed.2022.153975openalex-snapshot
Zuogui pills maintain the stemness of oogonial stem cells and alleviate cyclophosphamide-induced ovarian aging through Notch signaling pathway
inferred← citeshttps://doi.org/10.1016/j.phymed.2025.156452openalex-snapshot
Epimedin C promotes mitochondrial transfer and delays thymus atrophy in 4-VCD induced mimetic-menopausal mice
inferred← citeshttps://doi.org/10.1016/j.psj.2022.102033openalex-snapshot
Shudi Erzi San relieves ovary aging in laying hens
inferred← citeshttps://doi.org/10.1016/j.psj.2022.102258openalex-snapshot
Dietary supplementation with astaxanthin alleviates ovarian aging in aged laying hens by enhancing antioxidant capacity and increasing reproductive hormones
inferred← citeshttps://doi.org/10.1016/j.psj.2023.102545openalex-snapshot
Effects of dietary theabrownins on production performance, egg quality, and ovarian function of laying hens with different ages
inferred← citeshttps://doi.org/10.1016/j.psj.2023.102573openalex-snapshot
Supplemental dietary genistein improves the laying performance and antioxidant capacity of Hy-Line brown hens during the late laying period
inferred← citeshttps://doi.org/10.1016/j.psj.2024.104551openalex-snapshot
Age-related calcium signaling disturbance restricted cAMP metabolism and induced ovarian oxidation stress in laying ducks
inferred← citeshttps://doi.org/10.1016/j.psj.2025.105602openalex-snapshot
Spermidine enhances steroidogenesis by elevating eIF5Ahyp level in hierarchical follicular granulosa cells of the goose
inferred← citeshttps://doi.org/10.1016/j.rbmo.2015.09.017openalex-snapshot
Influence of paternal age on ongoing pregnancy rate at eight weeks' gestation in assisted reproduction
inferred← citeshttps://doi.org/10.1016/j.rbmo.2016.04.001openalex-snapshot
Can oocyte quality be augmented?
inferred← citeshttps://doi.org/10.1016/j.rbmo.2018.02.007openalex-snapshot
The role of mitochondrial activity in female fertility and assisted reproductive technologies: overview and current insights
inferred← citeshttps://doi.org/10.1016/j.rbmo.2019.03.205openalex-snapshot
Influence of resveratrol supplementation on IVF–embryo transfer cycle outcomes
inferred← citeshttps://doi.org/10.1016/j.rbmo.2020.01.026openalex-snapshot
Prospective randomized multicentre comparison on sibling oocytes comparing G-Series media system with antioxidants versus standard G-Series media system
inferred← citeshttps://doi.org/10.1016/j.rbmo.2020.04.011openalex-snapshot
Mitochondrial DNA content is not predictive of reproductive competence in euploid blastocysts
inferred← citeshttps://doi.org/10.1016/j.rbmo.2021.08.006openalex-snapshot
Reproductive senescence impairs the energy metabolism of human luteinized granulosa cells
inferred← citeshttps://doi.org/10.1016/j.rbmo.2023.103770openalex-snapshot
Nutritional supplements and IVF: an evidence-based approach
inferred← citeshttps://doi.org/10.1016/j.rbmo.2026.105734openalex-snapshot
Age-related female infertility: aetiological mechanisms and evidence-based and experimental interventions
inferred← citeshttps://doi.org/10.1016/j.rbms.2018.03.001openalex-snapshot
Herbal fertility treatments used in North America from colonial times to 1900, and their potential for improving the success rate of assisted reproductive technology
inferred← citeshttps://doi.org/10.1016/j.redox.2020.101680openalex-snapshot
Micellization of coenzyme Q by the fungicide caspofungin allows for safe intravenous administration to reach extreme supraphysiological concentrations
inferred← citeshttps://doi.org/10.1016/j.reprotox.2018.08.020openalex-snapshot
The influence of in vivo exposure to nonylphenol ethoxylate 10 (NP-10) on the ovarian reserve in a mouse model
inferred← citeshttps://doi.org/10.1016/j.rvsc.2020.07.013openalex-snapshot
Impact of oxidative stress on oocyte competence for in vitro embryo production programs
inferred← citeshttps://doi.org/10.1016/j.semcdb.2024.01.007openalex-snapshot
The role of mitochondrial dynamics in oocyte and early embryo development
inferred← citeshttps://doi.org/10.1016/j.stem.2026.07.013openalex-snapshot
Ovarian aging and systemic health: Mechanisms and emerging intervention strategies
inferred← citeshttps://doi.org/10.1016/j.tcb.2015.12.007openalex-snapshot
Understanding Ubiquinone
inferred← citeshttps://doi.org/10.1016/j.theriogenology.2019.10.011openalex-snapshot
Use of supplemental dietary coenzyme Q10 to improve testicular function and fertilization capacity in aged broiler breeder roosters
inferred← citeshttps://doi.org/10.1016/j.theriogenology.2020.10.009openalex-snapshot
CoQ10 improves meiotic maturation of pig oocytes through enhancing mitochondrial function and suppressing oxidative stress
inferred← citeshttps://doi.org/10.1016/j.theriogenology.2021.08.029openalex-snapshot
Supplementation of the freezing medium with Coenzyme Q10 attenuates oxidative stress and improves function of frozen-thawed giant grouper (Epinephelus lanceolatus) spermatozoa
inferred← citeshttps://doi.org/10.1016/j.theriogenology.2021.11.006openalex-snapshot
The effects of H22 tumor on the quality of oocytes and the development of early embryos from host mice: A single-cell RNA sequencing approach
inferred← citeshttps://doi.org/10.1016/j.theriogenology.2022.08.030openalex-snapshot
Apoptosis and glucocorticoid-related genes mRNA expression is modulated by coenzyme Q10 supplementation during in vitro maturation and vitrification of bovine oocytes and cumulus cells
inferred← citeshttps://doi.org/10.1016/j.theriogenology.2023.03.022openalex-snapshot
Mitochondrial activity and redox status in oocytes from old mice: The interplay between maternal and postovulatory aging
inferred← citeshttps://doi.org/10.1016/j.tibs.2017.06.008openalex-snapshot
Biochemistry of Mitochondrial Coenzyme Q Biosynthesis
inferred← citeshttps://doi.org/10.1016/j.tma.2026.03.001openalex-snapshot
Ubiquinol-mediated NRF2 activation enhances mitochondrial function and attenuates cellular senescence
inferred← citeshttps://doi.org/10.1016/j.yfrne.2026.101234openalex-snapshot
The importance of ovary-immune interactions in the context of age and disease
inferred← citeshttps://doi.org/10.1017/9781009025270.008openalex-snapshot
Optimal IVF Protocols for Women over 40 and Low Functional Ovarian Reserve
inferred← citeshttps://doi.org/10.1017/9781108611633.003openalex-snapshot
Endocrine Control of Reproduction
inferred← citeshttps://doi.org/10.1017/9781108891622.002openalex-snapshot
Individualized Ovarian Stimulation in Patients with Advanced Maternal Age and Premature Ovarian Aging
inferred← citeshttps://doi.org/10.1017/s0967199421000617openalex-snapshot
Coenzyme Q10 ameliorates the quality of mouse oocytes during in vitro culture
inferred← citeshttps://doi.org/10.1017/s2040174421000325openalex-snapshot
Advanced maternal age perturbs mouse embryo development and alters the phenotype of derived embryonic stem cells
inferred← citeshttps://doi.org/10.1038/d41586-022-01642-xopenalex-snapshot
Eggs remodel energy production to protect themselves from harm
inferred← citeshttps://doi.org/10.1038/s41419-020-03183-5openalex-snapshot
Quercetin promotes in vitro maturation of oocytes from humans and aged mice
inferred← citeshttps://doi.org/10.1038/s41422-022-00718-7openalex-snapshot
Unraveling female reproductive senescence to enhance healthy longevity
inferred← citeshttps://doi.org/10.1038/s41514-025-00216-1openalex-snapshot
Ovarian vascular aging: a hidden driver of mid-age female fertility decline
inferred← citeshttps://doi.org/10.1038/s41580-022-00517-3openalex-snapshot
Aneuploidy in mammalian oocytes and the impact of maternal ageing
inferred← citeshttps://doi.org/10.1038/s41590-024-01998-4openalex-snapshot
Novel coenzyme Q6 genetic variant increases susceptibility to pneumococcal disease
inferred← citeshttps://doi.org/10.1038/s41598-017-06372-zopenalex-snapshot
The lipid peroxidation product 4-hydroxynonenal contributes to oxidative stress-mediated deterioration of the ageing oocyte
inferred← citeshttps://doi.org/10.1038/s41598-019-46025-xopenalex-snapshot
Dysfunctional MDR-1 disrupts mitochondrial homeostasis in the oocyte and ovary
inferred← citeshttps://doi.org/10.1038/s41598-019-46459-3openalex-snapshot
Gas6 is a reciprocal regulator of mitophagy during mammalian oocyte maturation
inferred← citeshttps://doi.org/10.1038/s41598-025-29753-1openalex-snapshot
Protective effects of coenzyme Q10 against cyclophosphamide induced ovarian damage in rats
inferred← citeshttps://doi.org/10.1038/s42003-024-06888-xopenalex-snapshot
Maintaining mitochondrial DNA copy number mitigates ROS-induced oocyte decline and female reproductive aging
inferred← citeshttps://doi.org/10.1038/s43587-023-00435-9openalex-snapshot
Follicular communication breakdown in aging ovaries
inferred← citeshttps://doi.org/10.1038/s43587-023-00498-8openalex-snapshot
Polyamine metabolite spermidine rejuvenates oocyte quality by enhancing mitophagy during female reproductive aging
inferred← citeshttps://doi.org/10.1038/s43587-024-00697-xopenalex-snapshot
Rejuvenation of aged oocyte through exposure to young follicular microenvironment
inferred← citeshttps://doi.org/10.1038/s43587-024-00769-yopenalex-snapshot
Hallmarks of female reproductive aging in physiologic aging mice
inferred← citeshttps://doi.org/10.1038/s43587-024-00771-4openalex-snapshot
Emerging therapeutic strategies to mitigate female and male reproductive aging
inferred← citeshttps://doi.org/10.1038/s43587-026-01195-yopenalex-snapshot
Mitochondrial DNA leakage in oocytes activates cGAS-STING signaling to drive ovarian aging
inferred← citeshttps://doi.org/10.1039/d3bm00857fopenalex-snapshot
Synergetic EGCG and coenzyme Q10 DSPC liposome nanoparticles protect against myocardial infarction
inferred← citeshttps://doi.org/10.1039/d3fo02824kopenalex-snapshot
Efficacy of antioxidant supplementation in improving endocrine, hormonal, inflammatory, and metabolic statuses of PCOS: a meta-analysis and systematic review
inferred← citeshttps://doi.org/10.1039/d5fo00344jopenalex-snapshot
Multi-omics analysis reveals the attenuation effect of C-phycocyanin on aging-induced subfertility in female mice
inferred← citeshttps://doi.org/10.1039/d6mh01330aopenalex-snapshot
Bioinspired plant-derived extracellular vesicles enabling dual-targeting therapy for primary ovarian insufficiency
inferred← citeshttps://doi.org/10.1055/s-0035-1567826openalex-snapshot
Autologous Germline Mitochondrial Energy Transfer (AUGMENT) in Human Assisted Reproduction
inferred← citeshttps://doi.org/10.1055/s-0040-1721377openalex-snapshot
The Role of Oocyte Quality in Explaining “Unexplained” Infertility
inferred← citeshttps://doi.org/10.1055/s-0043-1772186openalex-snapshot
Effect of Endometriosis on Cumulus ATP, Number of Mitochondria and Oocyte Maturity in Cumulus Oocyte Complex in Mice
inferred← citeshttps://doi.org/10.1063/5.0150912openalex-snapshot
The performance of Indonesian native breeder hens subjected to the carrot juice supplementation in drinking water
inferred← citeshttps://doi.org/10.1071/rd16223openalex-snapshot
Effect and possible mechanisms of melatonin treatment on the quality and developmental potential of aged bovine oocytes
inferred← citeshttps://doi.org/10.1071/rd18340openalex-snapshot
Maternal age affects oocyte developmental potential at both ends of the age spectrum
inferred← citeshttps://doi.org/10.1080/01443615.2022.2114322openalex-snapshot
The therapeutic effects of coenzyme Q10 on surgically induced endometriosis in Sprague Dawley rats
inferred← citeshttps://doi.org/10.1080/03009734.2020.1751751openalex-snapshot
Adjuvants in IVF—evidence for what works and what does not work
inferred← citeshttps://doi.org/10.1080/13543784.2021.1896701openalex-snapshot
Investigational neuroprotective compounds in clinical trials for retinal disease
inferred← citeshttps://doi.org/10.1080/14647273.2023.2194554openalex-snapshot
The Effect of CoQ10 supplementation on ART treatment and oocyte quality in older women
inferred← citeshttps://doi.org/10.1080/15548627.2017.1390636openalex-snapshot
Piperlongumine restores the balance of autophagy and apoptosis by increasing BCL2 phosphorylation in rotenone-induced Parkinson disease models
inferred← citeshttps://doi.org/10.1080/15548627.2021.1946739openalex-snapshot
RAB7 activity is required for the regulation of mitophagy in oocyte meiosis and oocyte quality control during ovarian aging
inferred← citeshttps://doi.org/10.1080/19396368.2025.2562633openalex-snapshot
Exploring ovarian aging: unraveling the link between mitochondria status and oocyte as a determinant of gamete quality
inferred← citeshttps://doi.org/10.1080/19490976.2023.2295394openalex-snapshot
The influence of the gut microbiome on ovarian aging
inferred← citeshttps://doi.org/10.1086/721148openalex-snapshot
Inverse Lansing Effect: Maternal Age and Provisioning Affecting Daughters’ Longevity and Male Offspring Production
inferred← citeshttps://doi.org/10.1089/ars.2019.7986openalex-snapshot
Autophagy in Female Fertility: A Role in Oxidative Stress and Aging
inferred← citeshttps://doi.org/10.1089/biores.2017.0016openalex-snapshot
Supporting the One-Carbon Cycle Restores Ovarian Reserve in Subfertile Women: Absence of Correlation with Urinary Bisphenol A Concentration
inferred← citeshttps://doi.org/10.1093/biolre/ioaa139openalex-snapshot
Age-related alterations in fertilization-induced Ca2+ oscillations depend on the genetic background of mouse oocytes†
inferred← citeshttps://doi.org/10.1093/biolre/ioab002openalex-snapshot
Toxicant effects on mammalian oocyte mitochondria†
inferred← citeshttps://doi.org/10.1093/biolre/ioac024openalex-snapshot
Oocyte mitochondria—key regulators of oocyte function and potential therapeutic targets for improving fertility
inferred← citeshttps://doi.org/10.1093/biolre/ioae174openalex-snapshot
Pyrroloquinoline-quinone supplementation restores ovarian function and oocyte quality in a mouse model of advanced maternal age
inferred← citeshttps://doi.org/10.1093/biolre/ioaf129openalex-snapshot
Near infrared LED irradiation reverses the declining quality of mice post-ovulatory aging and reproductive aged oocytes
inferred← citeshttps://doi.org/10.1093/biolre/ioaf185openalex-snapshot
A role for the antioxidants coenzyme Q10 and pyrroloquinoline quinone in mitigating obesity-associated reproductive dysfunction
inferred← citeshttps://doi.org/10.1093/biolre/iox004openalex-snapshot
A single nucleotide polymorphism in COQ9 affects mitochondrial and ovarian function and fertility in Holstein cows†
inferred← citeshttps://doi.org/10.1093/biolre/ioy248openalex-snapshot
Alterations in oocyte mitochondrial number and function are related to spindle defects and occur with maternal aging in mice and humans†
inferred← citeshttps://doi.org/10.1093/biolre/ioz149openalex-snapshot
Ascorbic acid and CoQ10 ameliorate the reproductive ability of superoxide dismutase 1-deficient female mice†
inferred← citeshttps://doi.org/10.1093/hropen/hoae074openalex-snapshot
The interplay between mitochondrial DNA genotypes, female infertility, ovarian response, and mutagenesis in oocytes
inferred← citeshttps://doi.org/10.1093/humrep/deaa112openalex-snapshot
Germline nuclear transfer in mice may rescue poor embryo development associated with advanced maternal age and early embryo arrest
inferred← citeshttps://doi.org/10.1093/humrep/deaa300openalex-snapshot
Mitochondria-targeted therapeutics, MitoQ and BGP-15, reverse aging-associated meiotic spindle defects in mouse and human oocytes
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