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GPR109A deficiency promotes IL‐33 overproduction and type 2 immune response in food allergy in mice

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1016/j.immuni.2015.07.007openalex-snapshot

Barrier Epithelial Cells and the Control of Type 2 Immunity

inferredcites →https://doi.org/10.1016/j.jaci.2009.05.038openalex-snapshot

Intestinal barrier function: Molecular regulation and disease pathogenesis

inferredcites →https://doi.org/10.1016/j.jaci.2012.08.002openalex-snapshot

IL-33, but not thymic stromal lymphopoietin or IL-25, is central to mite and peanut allergic sensitization

inferredcites →https://doi.org/10.1016/j.jaci.2020.04.024openalex-snapshot

Environmental factors in epithelial barrier dysfunction

inferredcites →https://doi.org/10.1038/nrgastro.2016.187openalex-snapshot

Food allergy and the gut

inferredcites →https://doi.org/10.1073/pnas.1115884109openalex-snapshot

IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G

inferredcites →https://doi.org/10.1146/annurev-immunol-051116-052235openalex-snapshot

Metabolite-Sensing G Protein–Coupled Receptors—Facilitators of Diet-Related Immune Regulation

inferredcites →https://doi.org/10.1681/asn.2019101029openalex-snapshot

Dietary Fiber Protects against Diabetic Nephropathy through Short-Chain Fatty Acid–Mediated Activation of G Protein–Coupled Receptors GPR43 and GPR109A

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4795887openalex-extracted

Cinnamic Acid Improves Skeletal Muscle Hypertrophy and Metabolism Through Activation of Gpr109a/Pka Pathway

inferred← citeshttps://doi.org/10.1002/mnfr.202200300openalex-snapshot

GPR109a Regulates Phenotypic and Functional Alterations in Macrophages and the Progression of Type 1 Diabetes

inferred← citeshttps://doi.org/10.1016/j.apsb.2026.07.046openalex-snapshot

Intestinal epithelial CSE-derived H2S alleviates food allergy via modulating the IL-25/ILC2 axis

inferred← citeshttps://doi.org/10.1016/j.cellimm.2022.104633openalex-snapshot

Manipulating the microbiome to enhance oral tolerance in food allergy

inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.140661openalex-snapshot

Chickpea-resistant starch exhibits bioactive function for alleviating atopic dermatitis via regulating butyrate production

inferred← citeshttps://doi.org/10.1016/j.intimp.2021.108209openalex-snapshot

Effects of IL-33 on 3T3-L1 cells and obese mice models induced by a high-fat diet

inferred← citeshttps://doi.org/10.1016/j.intimp.2023.111428openalex-snapshot

Free fatty acid 3 receptor agonist AR420626 reduces allergic responses in asthma and eczema in mice

inferred← citeshttps://doi.org/10.1016/j.phymed.2025.156851openalex-snapshot

Cinnamic acid-GPR109A pathway improves skeletal muscle hypertrophy and metabolism

inferred← citeshttps://doi.org/10.1038/s41467-023-43622-3openalex-snapshot

Parabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a

inferred← citeshttps://doi.org/10.1039/d4fo03851gopenalex-snapshot

Human milk oligosaccharides and milk fat globule membrane reduce allergic reactions in mice through the modulation of gut microbiota and metabolic functions

inferred← citeshttps://doi.org/10.1039/d4fo04638bopenalex-snapshot

Human milk oligosaccharides 2′-fucosyllactose and 3-fucosyllactose attenuate ovalbumin-induced food allergy through immunoregulation and gut microbiota modulation

inferred← citeshttps://doi.org/10.1039/d5fo04181copenalex-snapshot

A comparative study of human milk oligosaccharides: 6′-sialyllactose enhances gut barrier function and immune homeostasis to alleviate food allergy

inferred← citeshttps://doi.org/10.1111/1541-4337.13097openalex-snapshot

Critical features of an in vitro intestinal absorption model to study the first key aspects underlying food allergen sensitization

inferred← citeshttps://doi.org/10.1111/all.15749openalex-snapshot

An update on recent developments and highlights in food allergy

inferred← citeshttps://doi.org/10.26599/fshw.2022.9250010openalex-snapshot

Milk fat globule membrane supplementation protects against β -lactoglobulininduced food allergy in mice via upregulation of regulatory T cells and enhancement of intestinal barrier in a microbiota-derived short-chain fatty acids manner

inferred← citeshttps://doi.org/10.3390/nu16010092openalex-snapshot

The Role of Gut Microbiota and Leaky Gut in the Pathogenesis of Food Allergy

inferred← citeshttps://doi.org/10.53730/ijhs.v7ns1.15305openalex-snapshot

Allergies: Un updated review article of food allergy

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